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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HIVEP1

Z-value: 0.89

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Transcription factors associated with HIVEP1

Gene Symbol Gene ID Gene Info
HIVEP1
ENSG00000095951.12 HIVEP zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIVEP1hg19_v2_chr6_+_12012536_12012571-0.374.6e-02Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_73072534 2.35 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr6_+_32605195 2.14 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr12_-_63328817 1.92 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr2_-_216300784 1.77 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr9_-_32526299 1.64 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_+_32407619 1.63 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr11_+_27062272 1.51 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr6_+_32709119 1.35 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr11_+_27062502 1.33 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_-_112970436 1.20 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr9_-_32526184 1.15 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr10_-_100027943 1.13 ENST00000260702.3
LOXL4
lysyl oxidase-like 4
chr14_+_75988768 1.05 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr5_-_149792295 1.03 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr14_+_77648167 1.01 ENST00000554346.1
ENST00000298351.4
TMEM63C
transmembrane protein 63C
chr6_-_32908792 0.98 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr16_+_57392684 0.96 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr14_+_75988851 0.94 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr8_-_101321584 0.89 ENST00000523167.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr19_+_45504688 0.89 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr5_-_35230434 0.89 ENST00000504500.1
PRLR
prolactin receptor
chr14_+_103589789 0.87 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr17_-_39093672 0.78 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr15_-_41522889 0.74 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
EXD1
exonuclease 3'-5' domain containing 1
chr7_+_24324726 0.74 ENST00000405982.1
NPY
neuropeptide Y
chr17_-_53499310 0.71 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr1_-_27339317 0.68 ENST00000289166.5
FAM46B
family with sequence similarity 46, member B
chr2_+_61108771 0.66 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr4_-_76944621 0.65 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr8_-_70747205 0.63 ENST00000260126.4
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr11_+_45792967 0.63 ENST00000378779.2
CTD-2210P24.4
Uncharacterized protein
chr14_-_35873856 0.63 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr4_-_74864386 0.62 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr16_+_31494323 0.60 ENST00000569576.1
ENST00000330498.3
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr9_-_37465396 0.60 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr16_+_2880157 0.59 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr6_+_138188551 0.58 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr15_-_90222642 0.58 ENST00000430628.2
PLIN1
perilipin 1
chr15_-_90222610 0.58 ENST00000300055.5
PLIN1
perilipin 1
chr3_-_187455680 0.58 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr22_+_50919944 0.55 ENST00000395738.2
ADM2
adrenomedullin 2
chr6_-_31324943 0.55 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr3_-_124839648 0.54 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr17_-_46623441 0.53 ENST00000330070.4
HOXB2
homeobox B2
chr17_-_41984835 0.51 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr12_-_72057571 0.51 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr2_+_97481974 0.49 ENST00000377060.3
ENST00000305510.3
CNNM3
cyclin M3
chr19_+_42212526 0.49 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
CEA
CEACAM5
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr6_-_52710893 0.48 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr11_-_17410869 0.48 ENST00000528731.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr19_-_5978090 0.48 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RANBP3
RAN binding protein 3
chr11_+_46316677 0.47 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr22_+_50919995 0.46 ENST00000362068.2
ENST00000395737.1
ADM2
adrenomedullin 2
chr6_+_29910301 0.45 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr12_-_113772835 0.45 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
SLC8B1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr7_-_132261223 0.45 ENST00000423507.2
PLXNA4
plexin A4
chr11_+_65190245 0.45 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr16_-_55909211 0.44 ENST00000520435.1
CES5A
carboxylesterase 5A
chr3_-_58563094 0.44 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr5_+_150591678 0.44 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr9_+_139921916 0.44 ENST00000314330.2
C9orf139
chromosome 9 open reading frame 139
chr16_-_55909255 0.43 ENST00000290567.9
CES5A
carboxylesterase 5A
chr16_-_55909272 0.43 ENST00000319165.9
CES5A
carboxylesterase 5A
chr17_-_78428487 0.43 ENST00000562672.2
CTD-2526A2.2
CTD-2526A2.2
chr12_+_48722763 0.43 ENST00000335017.1
H1FNT
H1 histone family, member N, testis-specific
chr10_+_114133773 0.43 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_+_4387983 0.42 ENST00000397958.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr8_-_10512569 0.42 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr5_+_161112563 0.41 ENST00000274545.5
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr2_-_227050079 0.41 ENST00000423838.1
AC068138.1
AC068138.1
chr17_-_74236382 0.41 ENST00000592271.1
ENST00000319945.6
ENST00000269391.6
RNF157
ring finger protein 157
chr5_+_161112754 0.41 ENST00000523217.1
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr7_+_24323782 0.40 ENST00000242152.2
ENST00000407573.1
NPY
neuropeptide Y
chr19_+_18496957 0.40 ENST00000252809.3
GDF15
growth differentiation factor 15
chr9_-_35103105 0.40 ENST00000452248.2
ENST00000356493.5
STOML2
stomatin (EPB72)-like 2
chr5_+_142149955 0.40 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr5_-_178054014 0.39 ENST00000520957.1
CLK4
CDC-like kinase 4
chr7_-_120498357 0.39 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr21_-_43373999 0.39 ENST00000380486.3
C2CD2
C2 calcium-dependent domain containing 2
chr15_-_55700216 0.39 ENST00000569205.1
CCPG1
cell cycle progression 1
chr12_+_10365404 0.39 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr11_-_8986474 0.39 ENST00000525069.1
TMEM9B
TMEM9 domain family, member B
chr6_-_4079334 0.38 ENST00000492651.1
ENST00000498677.1
ENST00000274673.3
FAM217A
family with sequence similarity 217, member A
chr1_+_111770232 0.38 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr7_-_8302298 0.38 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr1_+_156785425 0.37 ENST00000392302.2
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr11_+_118754475 0.37 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr6_-_29399744 0.37 ENST00000377154.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr19_-_52133588 0.37 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr1_+_111770278 0.37 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr14_-_24664540 0.37 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
TM9SF1
transmembrane 9 superfamily member 1
chr19_+_35225060 0.36 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chr2_-_88427568 0.35 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr19_+_39390587 0.35 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr22_-_50964849 0.35 ENST00000543927.1
ENST00000423348.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr7_+_107110488 0.35 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr20_+_2795626 0.34 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr1_+_156611704 0.34 ENST00000329117.5
BCAN
brevican
chr11_-_64510409 0.34 ENST00000394429.1
ENST00000394428.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_+_37940153 0.34 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr9_+_127054217 0.34 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr14_+_22573582 0.34 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr2_+_5832799 0.34 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr14_+_22771851 0.34 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39
chr16_+_33020496 0.33 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr14_-_106622419 0.33 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr16_-_33647696 0.33 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9
Uncharacterized protein
chr9_-_125693757 0.33 ENST00000373656.3
ZBTB26
zinc finger and BTB domain containing 26
chr6_+_43484760 0.33 ENST00000372389.3
ENST00000372344.2
ENST00000304004.3
ENST00000423780.1
POLR1C
polymerase (RNA) I polypeptide C, 30kDa
chr10_+_13142075 0.32 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr2_-_68694390 0.32 ENST00000377957.3
FBXO48
F-box protein 48
chr1_+_155051305 0.32 ENST00000368408.3
EFNA3
ephrin-A3
chr20_+_2276639 0.32 ENST00000381458.5
TGM3
transglutaminase 3
chr6_-_43484718 0.32 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr4_-_122085469 0.31 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr1_-_156918806 0.31 ENST00000315174.8
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr4_+_39046615 0.31 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr6_-_112115074 0.31 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chrX_+_117861535 0.30 ENST00000371666.3
ENST00000371642.1
IL13RA1
interleukin 13 receptor, alpha 1
chr10_-_93669233 0.30 ENST00000311575.5
FGFBP3
fibroblast growth factor binding protein 3
chr1_+_46640750 0.30 ENST00000372003.1
TSPAN1
tetraspanin 1
chr2_-_27558270 0.30 ENST00000454704.1
GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr17_-_41985096 0.30 ENST00000269095.4
ENST00000523220.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr1_+_41249539 0.30 ENST00000347132.5
ENST00000509682.2
KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr10_+_13142225 0.30 ENST00000378747.3
OPTN
optineurin
chr6_+_29691056 0.29 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr6_+_29691198 0.29 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr10_+_13141585 0.29 ENST00000378764.2
OPTN
optineurin
chr11_-_61735103 0.29 ENST00000529191.1
ENST00000529631.1
ENST00000530019.1
ENST00000529548.1
ENST00000273550.7
FTH1
ferritin, heavy polypeptide 1
chr6_-_43484621 0.29 ENST00000506469.1
ENST00000503972.1
YIPF3
Yip1 domain family, member 3
chr5_+_68389807 0.29 ENST00000380860.4
ENST00000504103.1
ENST00000502979.1
SLC30A5
solute carrier family 30 (zinc transporter), member 5
chr22_+_50986462 0.28 ENST00000395676.2
KLHDC7B
kelch domain containing 7B
chr14_-_106845789 0.28 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr22_-_38380543 0.28 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr3_-_66024213 0.28 ENST00000483466.1
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_161195781 0.28 ENST00000367988.3
TOMM40L
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr19_-_6591113 0.28 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr2_+_61108650 0.27 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_-_67142710 0.27 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr3_+_113775576 0.27 ENST00000485050.1
ENST00000281273.4
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr19_+_39390320 0.27 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr9_-_136344197 0.27 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr21_-_42880075 0.27 ENST00000332149.5
TMPRSS2
transmembrane protease, serine 2
chr7_-_99097863 0.27 ENST00000426306.2
ENST00000337673.6
ZNF394
zinc finger protein 394
chr2_-_43453734 0.27 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr7_+_100318423 0.27 ENST00000252723.2
EPO
erythropoietin
chr11_+_64053005 0.26 ENST00000538032.1
GPR137
G protein-coupled receptor 137
chr3_-_194072019 0.26 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr9_-_14722715 0.26 ENST00000380911.3
CER1
cerberus 1, DAN family BMP antagonist
chr15_+_85923856 0.26 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr3_-_130465604 0.26 ENST00000356763.3
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr9_-_71629010 0.26 ENST00000377276.2
PRKACG
protein kinase, cAMP-dependent, catalytic, gamma
chr1_+_156119466 0.25 ENST00000414683.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_+_64681641 0.25 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr11_+_64052294 0.25 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr6_+_33176265 0.25 ENST00000374656.4
RING1
ring finger protein 1
chr11_-_67276100 0.25 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr4_+_139936905 0.25 ENST00000280614.2
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr20_+_3024266 0.25 ENST00000245983.2
ENST00000359100.2
ENST00000359987.1
GNRH2
gonadotropin-releasing hormone 2
chr3_+_186353756 0.25 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr11_-_35441597 0.25 ENST00000395753.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_+_56116771 0.24 ENST00000568956.1
ZNF865
zinc finger protein 865
chr11_-_72492903 0.24 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr6_-_31239846 0.24 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
HLA-C
major histocompatibility complex, class I, C
chr11_-_8986279 0.24 ENST00000534025.1
TMEM9B
TMEM9 domain family, member B
chr3_-_46069223 0.24 ENST00000309285.3
XCR1
chemokine (C motif) receptor 1
chr3_-_156878540 0.24 ENST00000461804.1
CCNL1
cyclin L1
chr7_+_73442422 0.24 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN
elastin
chr12_+_72056773 0.24 ENST00000308086.2
THAP2
THAP domain containing, apoptosis associated protein 2
chr16_+_53738053 0.24 ENST00000394647.3
FTO
fat mass and obesity associated
chr19_-_50836762 0.24 ENST00000474951.1
ENST00000391818.2
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr17_-_34207295 0.24 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr11_+_64052454 0.24 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr4_+_106816644 0.24 ENST00000506666.1
ENST00000503451.1
NPNT
nephronectin
chr5_+_147443534 0.24 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5
serine peptidase inhibitor, Kazal type 5
chr14_+_103243813 0.23 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr11_-_8985927 0.23 ENST00000528117.1
ENST00000309134.5
TMEM9B
TMEM9 domain family, member B
chr17_+_43209967 0.23 ENST00000431281.1
ENST00000591859.1
ACBD4
acyl-CoA binding domain containing 4
chr11_+_64052944 0.23 ENST00000535675.1
ENST00000543383.1
GPR137
G protein-coupled receptor 137
chr15_+_91411810 0.23 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr11_+_64052692 0.23 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr17_-_56605341 0.22 ENST00000583114.1
SEPT4
septin 4
chr19_+_17416609 0.22 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr3_+_52821841 0.22 ENST00000405128.3
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr1_+_156611960 0.22 ENST00000361588.5
BCAN
brevican
chr12_-_57504069 0.22 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr8_-_17533838 0.22 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr7_+_73442102 0.21 ENST00000445912.1
ENST00000252034.7
ELN
elastin
chr11_+_65292538 0.21 ENST00000270176.5
ENST00000525364.1
ENST00000420247.2
ENST00000533862.1
ENST00000279270.6
ENST00000524944.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chrX_+_78426469 0.21 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr14_-_24616426 0.21 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr7_+_73442487 0.21 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr19_-_55628927 0.21 ENST00000263433.3
ENST00000376393.2
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr3_+_9773409 0.21 ENST00000433861.2
ENST00000424362.1
ENST00000383829.2
ENST00000302054.3
ENST00000420291.1
BRPF1
bromodomain and PHD finger containing, 1
chr3_-_49131013 0.21 ENST00000424300.1
QRICH1
glutamine-rich 1
chr7_-_27213893 0.21 ENST00000283921.4
HOXA10
homeobox A10
chr11_-_75062730 0.21 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr11_+_128761220 0.21 ENST00000529694.1
KCNJ5
potassium inwardly-rectifying channel, subfamily J, member 5
chr1_-_160001737 0.21 ENST00000368090.2
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr12_-_54982300 0.21 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.7 2.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6 1.8 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.3 2.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.6 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.2 1.0 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 0.6 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 1.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.5 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 0.5 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.5 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.6 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 1.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.3 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 1.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 2.1 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.3 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.2 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.4 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.9 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.1 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.1 0.1 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.2 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.9 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.3 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.3 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 3.7 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.9 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.1 GO:0072019 establishment or maintenance of actin cytoskeleton polarity(GO:0030950) carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.1 GO:1904339 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.7 GO:0001525 angiogenesis(GO:0001525)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 1.1 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.5 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.1 GO:1905245 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) negative regulation of neurofibrillary tangle assembly(GO:1902997) regulation of aspartic-type peptidase activity(GO:1905245) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0032914 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690) positive regulation of bone development(GO:1903012)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 1.0 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.0 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.7 GO:1990923 PET complex(GO:1990923)
0.2 2.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.9 GO:0042612 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1 1.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.3 GO:0097444 spine apparatus(GO:0097444)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.8 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.1 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.3 GO:0072687 lateral loop(GO:0043219) meiotic spindle(GO:0072687)
0.0 0.2 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.9 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 5.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.9 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.6 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.6 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.1 GO:0038181 vitamin D binding(GO:0005499) bile acid receptor activity(GO:0038181) vitamin D response element binding(GO:0070644)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 2.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 3.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 3.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex