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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HMX1

Z-value: 0.64

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Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
HMX1
ENSG00000215612.5 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX1hg19_v2_chr4_-_8873531_88735430.212.6e-01Click!

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_21494654 2.16 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr2_+_106682103 2.09 ENST00000238044.3
C2orf40
chromosome 2 open reading frame 40
chr2_+_106682135 1.73 ENST00000437659.1
C2orf40
chromosome 2 open reading frame 40
chr16_-_776431 1.42 ENST00000293889.6
CCDC78
coiled-coil domain containing 78
chr18_-_45935663 1.16 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
ZBTB7C
zinc finger and BTB domain containing 7C
chr1_-_46598371 1.10 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr1_-_46598284 1.08 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr20_+_44098346 1.04 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr13_+_25254545 1.03 ENST00000218548.6
ATP12A
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr5_+_156693159 0.98 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_+_156693091 0.95 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr13_+_35516390 0.94 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr19_-_14316980 0.92 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr3_-_107941209 0.84 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr3_+_69788576 0.80 ENST00000352241.4
ENST00000448226.2
MITF
microphthalmia-associated transcription factor
chr22_-_18923655 0.74 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
PRODH
proline dehydrogenase (oxidase) 1
chr13_+_25254693 0.73 ENST00000381946.3
ATP12A
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
chr2_-_27712583 0.72 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr11_-_110561721 0.68 ENST00000357139.3
ARHGAP20
Rho GTPase activating protein 20
chr22_-_29196030 0.68 ENST00000405219.3
XBP1
X-box binding protein 1
chr17_-_72709050 0.64 ENST00000583937.1
ENST00000301573.9
ENST00000326165.6
ENST00000469092.1
CD300LF
CD300 molecule-like family member f
chr16_-_70712229 0.61 ENST00000562883.2
MTSS1L
metastasis suppressor 1-like
chr1_-_177133818 0.61 ENST00000424564.2
ENST00000361833.2
ASTN1
astrotactin 1
chr5_-_81046922 0.60 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr2_-_46769694 0.60 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr22_-_29196546 0.58 ENST00000403532.3
ENST00000216037.6
XBP1
X-box binding protein 1
chr20_+_44098385 0.56 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr17_-_6947225 0.54 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11
solute carrier family 16, member 11
chr19_+_41305330 0.54 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr9_+_976964 0.54 ENST00000190165.2
DMRT3
doublesex and mab-3 related transcription factor 3
chr1_-_110052302 0.52 ENST00000369864.4
ENST00000369862.1
AMIGO1
adhesion molecule with Ig-like domain 1
chr12_-_15374343 0.52 ENST00000256953.2
ENST00000546331.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chr19_+_41305627 0.51 ENST00000593525.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr3_-_107941230 0.51 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr8_-_17270809 0.51 ENST00000180173.5
ENST00000521857.1
MTMR7
myotubularin related protein 7
chr19_+_41305740 0.50 ENST00000596517.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr19_+_41305612 0.49 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_-_233352531 0.49 ENST00000304546.1
ECEL1
endothelin converting enzyme-like 1
chr14_+_56585048 0.49 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr17_-_72968809 0.49 ENST00000530857.1
ENST00000425042.2
HID1
HID1 domain containing
chr16_+_30210552 0.48 ENST00000338971.5
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr12_+_8234807 0.48 ENST00000339754.5
NECAP1
NECAP endocytosis associated 1
chr16_+_30212378 0.47 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_28996364 0.47 ENST00000564277.1
LAT
linker for activation of T cells
chr12_+_41831485 0.46 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr1_+_9648921 0.46 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
TMEM201
transmembrane protein 201
chr19_+_41305085 0.46 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr11_+_6502675 0.45 ENST00000254616.6
ENST00000530751.1
TIMM10B
translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr4_-_141348789 0.44 ENST00000414773.1
CLGN
calmegin
chr7_-_19184929 0.44 ENST00000275461.3
FERD3L
Fer3-like bHLH transcription factor
chr19_+_41305406 0.43 ENST00000406058.2
ENST00000593726.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr4_-_141348999 0.42 ENST00000325617.5
CLGN
calmegin
chr19_+_38085731 0.42 ENST00000589117.1
ZNF540
zinc finger protein 540
chr7_-_37488834 0.41 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr17_-_47755436 0.41 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP
speckle-type POZ protein
chr1_+_156338993 0.39 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr13_-_97646604 0.39 ENST00000298440.1
ENST00000543457.1
ENST00000541038.1
OXGR1
oxoglutarate (alpha-ketoglutarate) receptor 1
chr20_-_3140490 0.38 ENST00000449731.1
ENST00000380266.3
UBOX5
FASTKD5
U-box domain containing 5
FAST kinase domains 5
chr7_-_105332084 0.38 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr16_+_29472707 0.37 ENST00000565290.1
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr1_-_217311090 0.37 ENST00000493603.1
ENST00000366940.2
ESRRG
estrogen-related receptor gamma
chr5_-_81046841 0.36 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr16_-_70713928 0.36 ENST00000576338.1
MTSS1L
metastasis suppressor 1-like
chr3_-_192445289 0.36 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr8_+_145726472 0.36 ENST00000528430.1
PPP1R16A
protein phosphatase 1, regulatory subunit 16A
chr15_-_58306295 0.36 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr15_+_33010175 0.34 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr5_-_81046904 0.34 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr17_-_27278445 0.34 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr1_-_207095324 0.33 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr19_-_45579762 0.33 ENST00000303809.2
ZNF296
zinc finger protein 296
chr20_-_22559211 0.33 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr2_+_204801471 0.33 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr17_-_27278304 0.32 ENST00000577226.1
PHF12
PHD finger protein 12
chr11_+_66624527 0.32 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr18_-_47721447 0.32 ENST00000285039.7
MYO5B
myosin VB
chr17_+_40440481 0.32 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr5_+_10353780 0.32 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr16_+_67226019 0.31 ENST00000379378.3
E2F4
E2F transcription factor 4, p107/p130-binding
chr4_-_122854193 0.31 ENST00000513531.1
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr9_+_100000717 0.31 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180
coiled-coil domain containing 180
chr11_+_1411503 0.29 ENST00000526678.1
BRSK2
BR serine/threonine kinase 2
chr16_+_56385290 0.29 ENST00000564727.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr7_-_156685841 0.29 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chrX_+_13587712 0.29 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr8_-_75233563 0.27 ENST00000342232.4
JPH1
junctophilin 1
chr22_-_39268192 0.27 ENST00000216083.6
CBX6
chromobox homolog 6
chr22_-_38349552 0.27 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23
chromosome 22 open reading frame 23
chr17_-_62097904 0.27 ENST00000583366.1
ICAM2
intercellular adhesion molecule 2
chr18_-_56940611 0.27 ENST00000256852.7
ENST00000334889.3
RAX
retina and anterior neural fold homeobox
chr9_-_140082983 0.26 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr6_-_2245892 0.25 ENST00000380815.4
GMDS
GDP-mannose 4,6-dehydratase
chr20_-_35374456 0.25 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG3
NDRG family member 3
chr21_-_40685504 0.25 ENST00000380800.3
BRWD1
bromodomain and WD repeat domain containing 1
chr1_-_28241226 0.24 ENST00000373912.3
ENST00000373909.3
RPA2
replication protein A2, 32kDa
chr1_-_207095212 0.23 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr12_+_125478241 0.23 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr7_-_127032363 0.23 ENST00000393312.1
ZNF800
zinc finger protein 800
chr16_+_28996416 0.23 ENST00000395456.2
ENST00000454369.2
LAT
linker for activation of T cells
chr1_-_28241024 0.23 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chr17_-_42298201 0.23 ENST00000527034.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr12_+_70133152 0.22 ENST00000550536.1
ENST00000362025.5
RAB3IP
RAB3A interacting protein
chr16_+_19535133 0.22 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr16_+_19535235 0.22 ENST00000565376.2
ENST00000396208.2
CCP110
centriolar coiled coil protein 110kDa
chr19_+_41313017 0.22 ENST00000595621.1
ENST00000595051.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr16_-_20753114 0.22 ENST00000396083.2
THUMPD1
THUMP domain containing 1
chr8_-_26724784 0.22 ENST00000380573.3
ADRA1A
adrenoceptor alpha 1A
chr11_+_61129456 0.22 ENST00000278826.6
TMEM138
transmembrane protein 138
chr15_+_89346699 0.22 ENST00000558207.1
ACAN
aggrecan
chr8_+_145438870 0.21 ENST00000527931.1
FAM203B
family with sequence similarity 203, member B
chr17_-_41132010 0.21 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1
PTGES3L-AARSD1 readthrough
chr4_-_151936865 0.21 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr6_+_2246023 0.20 ENST00000530833.1
ENST00000525811.1
ENST00000534441.1
ENST00000533653.1
ENST00000534468.1
GMDS-AS1
GMDS antisense RNA 1 (head to head)
chr10_-_99531709 0.20 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr15_+_89402148 0.20 ENST00000560601.1
ACAN
aggrecan
chr1_-_109940550 0.20 ENST00000256637.6
SORT1
sortilin 1
chr15_+_89346657 0.20 ENST00000439576.2
ACAN
aggrecan
chr11_+_43702322 0.20 ENST00000395700.4
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr16_-_49315731 0.20 ENST00000219197.6
CBLN1
cerebellin 1 precursor
chrX_+_22050546 0.20 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr8_+_38854368 0.19 ENST00000466936.1
ADAM9
ADAM metallopeptidase domain 9
chr6_+_33043703 0.19 ENST00000418931.2
ENST00000535465.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr20_-_41818536 0.19 ENST00000373193.3
ENST00000373198.4
ENST00000373201.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chrX_-_71933888 0.19 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1
phosphorylase kinase, alpha 1 (muscle)
chr20_+_30640004 0.19 ENST00000520553.1
ENST00000518730.1
ENST00000375852.2
HCK
hemopoietic cell kinase
chr7_-_16844611 0.19 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr2_+_46769798 0.18 ENST00000238738.4
RHOQ
ras homolog family member Q
chr13_-_84456527 0.18 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr3_-_156534754 0.18 ENST00000472943.1
ENST00000473352.1
LINC00886
long intergenic non-protein coding RNA 886
chr2_-_220435963 0.18 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr5_+_141016508 0.18 ENST00000444782.1
ENST00000521367.1
ENST00000297164.3
RELL2
RELT-like 2
chr2_-_24583314 0.18 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
ITSN2
intersectin 2
chr12_-_55378452 0.18 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr9_+_137967268 0.17 ENST00000371799.4
ENST00000277415.11
OLFM1
olfactomedin 1
chr5_+_141016969 0.17 ENST00000518856.1
RELL2
RELT-like 2
chr19_+_34895289 0.17 ENST00000246535.3
PDCD2L
programmed cell death 2-like
chr11_+_59522837 0.17 ENST00000437946.2
STX3
syntaxin 3
chr15_-_41166414 0.17 ENST00000220507.4
RHOV
ras homolog family member V
chr5_-_24645078 0.17 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr11_-_76155700 0.17 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr14_+_63671577 0.17 ENST00000555125.1
RHOJ
ras homolog family member J
chr16_-_18937726 0.17 ENST00000389467.3
ENST00000446231.2
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr22_-_39268308 0.17 ENST00000407418.3
CBX6
chromobox homolog 6
chr14_+_58666824 0.16 ENST00000254286.4
ACTR10
actin-related protein 10 homolog (S. cerevisiae)
chr8_+_121137333 0.16 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1
collagen, type XIV, alpha 1
chr5_+_139027877 0.16 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr21_-_40685477 0.16 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr6_-_10882174 0.16 ENST00000379491.4
GCM2
glial cells missing homolog 2 (Drosophila)
chr14_-_101034407 0.16 ENST00000443071.2
ENST00000557378.1
BEGAIN
brain-enriched guanylate kinase-associated
chr2_-_220436248 0.16 ENST00000265318.4
OBSL1
obscurin-like 1
chrX_+_53123314 0.16 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5
long intergenic non-protein coding RNA 1155
chr16_+_11038403 0.16 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr20_+_60813535 0.16 ENST00000358053.2
ENST00000313733.3
ENST00000439951.2
OSBPL2
oxysterol binding protein-like 2
chr20_-_41818373 0.16 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr7_-_150675372 0.16 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_-_85930246 0.16 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr19_+_496454 0.16 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr11_-_19223523 0.15 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr12_+_100867694 0.15 ENST00000392986.3
ENST00000549996.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr11_+_59522900 0.15 ENST00000529177.1
STX3
syntaxin 3
chr1_-_197744322 0.15 ENST00000235453.4
DENND1B
DENN/MADD domain containing 1B
chr17_+_79989500 0.15 ENST00000306897.4
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr17_-_8151353 0.15 ENST00000315684.8
CTC1
CTS telomere maintenance complex component 1
chr3_-_67705006 0.15 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
SUCLG2
succinate-CoA ligase, GDP-forming, beta subunit
chr17_+_79679299 0.15 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr6_+_2245982 0.15 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS-AS1
GMDS antisense RNA 1 (head to head)
chr20_+_30639991 0.14 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
HCK
hemopoietic cell kinase
chr14_-_103523745 0.14 ENST00000361246.2
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr1_-_33168336 0.14 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr16_+_15528332 0.14 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr6_+_20403997 0.14 ENST00000535432.1
E2F3
E2F transcription factor 3
chr6_-_89927151 0.14 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr1_-_197744390 0.14 ENST00000367396.3
DENND1B
DENN/MADD domain containing 1B
chr13_-_38443860 0.14 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4
transient receptor potential cation channel, subfamily C, member 4
chr9_-_26892765 0.14 ENST00000520187.1
ENST00000333916.5
CAAP1
caspase activity and apoptosis inhibitor 1
chr17_+_79679369 0.14 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr3_+_49711777 0.14 ENST00000442186.1
ENST00000438011.1
ENST00000457042.1
APEH
acylaminoacyl-peptide hydrolase
chr16_+_28996572 0.13 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT
linker for activation of T cells
chr4_+_86396265 0.13 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr4_-_151936416 0.13 ENST00000510413.1
ENST00000507224.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr12_+_7060432 0.13 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_8102714 0.13 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr19_-_10697895 0.13 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr17_+_42836329 0.13 ENST00000200557.6
ADAM11
ADAM metallopeptidase domain 11
chr2_-_175462934 0.13 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr1_-_54405773 0.13 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr16_+_29984962 0.13 ENST00000308893.4
TAOK2
TAO kinase 2
chr19_+_38085768 0.13 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
ZNF540
zinc finger protein 540
chr14_-_51561784 0.13 ENST00000360392.4
TRIM9
tripartite motif containing 9
chr20_+_49348081 0.13 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr19_-_18385221 0.13 ENST00000595654.2
ENST00000593659.1
ENST00000599528.1
KIAA1683
KIAA1683
chr22_-_24093267 0.13 ENST00000341976.3
ZNF70
zinc finger protein 70
chr1_+_202431859 0.12 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr14_+_105781048 0.12 ENST00000458164.2
ENST00000447393.1
PACS2
phosphofurin acidic cluster sorting protein 2
chr16_+_11038345 0.12 ENST00000409790.1
CLEC16A
C-type lectin domain family 16, member A
chr10_-_7708918 0.12 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr4_-_54457783 0.12 ENST00000263925.7
ENST00000512247.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chrX_-_153285251 0.12 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr17_-_47755338 0.12 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chr9_-_130616915 0.11 ENST00000344849.3
ENG
endoglin

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 1.3 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.2 3.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 3.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 0.6 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.2 1.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 1.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.7 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 1.0 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.3 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 0.3 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.5 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.3 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 1.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.3 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.8 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.2 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 2.1 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 1.9 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.5 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.4 GO:0033504 floor plate development(GO:0033504)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.4 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.3 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0021894 regulation of neuron maturation(GO:0014041) cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0090027 negative regulation of SMAD protein import into nucleus(GO:0060392) negative regulation of monocyte chemotaxis(GO:0090027)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.5 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.4 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.3 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.6 GO:0090662 ATP hydrolysis coupled proton transport(GO:0015991) phagosome acidification(GO:0090383) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.5 GO:0003016 respiratory system process(GO:0003016)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.4 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.2 GO:1900038 negative regulation of vascular permeability(GO:0043116) negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 1.4 GO:0098536 deuterosome(GO:0098536)
0.2 0.7 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.5 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 1.4 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 2.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.3 1.6 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 3.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 0.6 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 0.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 2.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 1.0 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.6 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0055131 phosphorelay sensor kinase activity(GO:0000155) C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1