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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HMX2

Z-value: 0.49

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Transcription factors associated with HMX2

Gene Symbol Gene ID Gene Info
HMX2
ENSG00000188816.3 H6 family homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX2hg19_v2_chr10_+_124907638_1249076600.212.5e-01Click!

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_146781153 0.69 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr6_-_27858570 0.65 ENST00000359303.2
HIST1H3J
histone cluster 1, H3j
chr1_-_111174054 0.65 ENST00000369770.3
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr1_+_209878182 0.61 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr18_+_42260861 0.56 ENST00000282030.5
SETBP1
SET binding protein 1
chr9_+_27109392 0.56 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr17_-_29641084 0.55 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr19_+_58144529 0.50 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr7_+_123241908 0.50 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr1_-_110933611 0.48 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr6_+_151561085 0.44 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr6_-_26199471 0.44 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr10_-_121296045 0.41 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr7_-_7680601 0.38 ENST00000396682.2
RPA3
replication protein A3, 14kDa
chr4_-_39034542 0.37 ENST00000344606.6
TMEM156
transmembrane protein 156
chr19_+_15852203 0.36 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr2_+_211342432 0.36 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr10_+_32873190 0.34 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr8_+_77318769 0.34 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr1_+_33546714 0.32 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC
arginine decarboxylase
chr10_-_7513904 0.32 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr2_+_158114051 0.32 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr21_-_34185944 0.31 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr13_+_24144509 0.31 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr4_-_168155169 0.30 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr15_+_41056255 0.30 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr12_+_81471816 0.30 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr15_+_41056218 0.30 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr1_-_151804314 0.29 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr6_+_26124373 0.29 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr17_-_15469590 0.29 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr4_-_138453606 0.28 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr1_-_110933663 0.28 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr17_+_67498538 0.28 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chrX_+_105937068 0.28 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr3_+_122785895 0.28 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr5_-_114961673 0.27 ENST00000333314.3
TMED7-TICAM2
TMED7-TICAM2 readthrough
chr8_-_93978309 0.27 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr6_+_25652501 0.26 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chr1_+_99127225 0.25 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr11_+_122753391 0.25 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr21_+_31768348 0.25 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr19_-_36001113 0.25 ENST00000434389.1
DMKN
dermokine
chr11_+_7618413 0.24 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_205290865 0.23 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr6_+_25754927 0.23 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr6_-_51952367 0.23 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr3_-_108836977 0.23 ENST00000232603.5
MORC1
MORC family CW-type zinc finger 1
chr10_-_61900762 0.23 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_153979315 0.23 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr8_-_93978333 0.22 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr8_-_93978346 0.22 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chr6_-_151773232 0.22 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr7_+_97361218 0.22 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr17_-_295730 0.22 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr3_-_121379739 0.21 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr11_-_74442430 0.21 ENST00000376332.3
CHRDL2
chordin-like 2
chr4_+_25915822 0.21 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr7_-_84569561 0.20 ENST00000439105.1
AC074183.4
AC074183.4
chr4_+_25915896 0.20 ENST00000514384.1
SMIM20
small integral membrane protein 20
chrX_+_71996972 0.20 ENST00000334036.5
DMRTC1B
DMRT-like family C1B
chr2_-_160654745 0.20 ENST00000259053.4
ENST00000429078.2
CD302
CD302 molecule
chr19_+_9361606 0.19 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr6_-_26199499 0.19 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr7_+_5920429 0.19 ENST00000242104.5
OCM
oncomodulin
chr18_+_45778672 0.18 ENST00000600091.1
AC091150.1
HCG1818186; Uncharacterized protein
chr17_-_38821373 0.18 ENST00000394052.3
KRT222
keratin 222
chr12_+_47473369 0.18 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr4_-_70518941 0.18 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr11_-_327537 0.17 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr4_-_120243545 0.17 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr9_-_116102562 0.17 ENST00000374193.4
ENST00000465979.1
WDR31
WD repeat domain 31
chr9_-_116102530 0.17 ENST00000374195.3
ENST00000341761.4
WDR31
WD repeat domain 31
chr5_+_169659950 0.17 ENST00000593851.1
C5orf58
chromosome 5 open reading frame 58
chr3_+_75955817 0.16 ENST00000487694.3
ENST00000602589.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr7_-_87856303 0.16 ENST00000394641.3
SRI
sorcin
chr7_-_87856280 0.16 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr10_-_95241951 0.16 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr6_-_26124138 0.16 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr11_-_101000445 0.16 ENST00000534013.1
PGR
progesterone receptor
chr3_+_173116225 0.16 ENST00000457714.1
NLGN1
neuroligin 1
chr17_-_29641104 0.16 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr18_-_24765248 0.16 ENST00000580774.1
ENST00000284224.8
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr2_+_108994633 0.16 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr17_-_73663168 0.16 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr2_+_24272543 0.16 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr12_-_72057571 0.15 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr1_-_67266939 0.15 ENST00000304526.2
INSL5
insulin-like 5
chr21_+_17909594 0.15 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chrX_+_79675965 0.14 ENST00000308293.5
FAM46D
family with sequence similarity 46, member D
chr14_-_20801427 0.14 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr19_-_52674896 0.14 ENST00000322146.8
ENST00000597065.1
ZNF836
zinc finger protein 836
chr10_-_99205607 0.14 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr4_-_26492076 0.14 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chr15_+_67835517 0.14 ENST00000395476.2
MAP2K5
mitogen-activated protein kinase kinase 5
chr5_+_3596168 0.14 ENST00000302006.3
IRX1
iroquois homeobox 1
chr1_+_70820451 0.14 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chr7_-_14880892 0.14 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr17_-_73663245 0.14 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr19_-_52674696 0.14 ENST00000597252.1
ZNF836
zinc finger protein 836
chr7_+_77325738 0.13 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr6_+_64345698 0.13 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHF3
PHD finger protein 3
chr1_+_64669294 0.13 ENST00000371077.5
UBE2U
ubiquitin-conjugating enzyme E2U (putative)
chr1_-_109935819 0.13 ENST00000538502.1
SORT1
sortilin 1
chr7_+_75024903 0.12 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chrX_+_36053908 0.12 ENST00000378660.2
CHDC2
calponin homology domain containing 2
chr15_+_54305101 0.12 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C
unc-13 homolog C (C. elegans)
chr4_-_155511887 0.12 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr12_+_133614119 0.12 ENST00000327668.7
ZNF84
zinc finger protein 84
chr3_-_46249878 0.12 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chr13_+_27998681 0.12 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr8_-_93978357 0.12 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK
triple QxxK/R motif containing
chr7_-_77325545 0.11 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L-AS1
RSBN1L antisense RNA 1
chr10_-_115613828 0.11 ENST00000361384.2
DCLRE1A
DNA cross-link repair 1A
chr6_+_26199737 0.11 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chrX_+_134478706 0.11 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
ZNF449
zinc finger protein 449
chr4_-_48782259 0.11 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr12_-_112279694 0.11 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1
MAPKAPK5 antisense RNA 1
chr14_+_65381079 0.11 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
CHURC1
FNTB
CHURC1-FNTB
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr12_-_10151773 0.11 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr2_+_1417228 0.11 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO
thyroid peroxidase
chr14_+_57857262 0.11 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr5_+_119867159 0.11 ENST00000505123.1
PRR16
proline rich 16
chr1_+_109102652 0.10 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr13_-_46756351 0.10 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr9_-_111882195 0.10 ENST00000374586.3
TMEM245
transmembrane protein 245
chr2_-_201374781 0.10 ENST00000359878.3
ENST00000409157.1
KCTD18
potassium channel tetramerization domain containing 18
chr10_-_49813090 0.10 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr5_-_22853429 0.10 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr5_+_150404904 0.10 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr12_+_10163231 0.10 ENST00000396502.1
ENST00000338896.5
CLEC12B
C-type lectin domain family 12, member B
chr6_-_106773491 0.10 ENST00000360666.4
ATG5
autophagy related 5
chr9_-_98784042 0.09 ENST00000412122.2
LINC00092
long intergenic non-protein coding RNA 92
chr6_-_46293378 0.09 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr2_-_190044480 0.09 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr5_-_58295712 0.09 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_37962018 0.09 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr19_+_41281416 0.09 ENST00000597140.1
MIA
melanoma inhibitory activity
chr14_-_50864006 0.09 ENST00000216378.2
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr3_+_111697843 0.09 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr16_-_21663919 0.09 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr1_-_108231101 0.09 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr11_-_40315640 0.08 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_-_44384291 0.08 ENST00000324394.6
ZNF404
zinc finger protein 404
chrX_+_36254051 0.08 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr12_-_122985067 0.08 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr17_+_54230819 0.08 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr1_+_144151520 0.08 ENST00000369372.4
NBPF8
neuroblastoma breakpoint family, member 8
chr20_-_47804894 0.08 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chr12_+_107712173 0.08 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr1_-_202858227 0.08 ENST00000367262.3
RABIF
RAB interacting factor
chr10_-_95242044 0.07 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr3_+_119013185 0.07 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr6_+_148663729 0.07 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr5_+_61602055 0.07 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr12_-_49463753 0.07 ENST00000301068.6
RHEBL1
Ras homolog enriched in brain like 1
chr4_+_76649797 0.07 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr15_-_40074996 0.07 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr14_+_32798462 0.06 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr14_+_32798547 0.06 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr6_-_116833500 0.06 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr14_+_31091511 0.06 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
SCFD1
sec1 family domain containing 1
chr20_+_33104199 0.06 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
DYNLRB1
dynein, light chain, roadblock-type 1
chr17_+_8243154 0.05 ENST00000328248.2
ENST00000584943.1
ODF4
outer dense fiber of sperm tails 4
chr12_-_13248598 0.05 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr4_-_69817481 0.05 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr3_+_145782358 0.05 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr17_+_28268623 0.05 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr3_-_187009798 0.05 ENST00000337774.5
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr19_+_52772821 0.04 ENST00000439461.1
ZNF766
zinc finger protein 766
chr8_-_101571964 0.04 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46
ankyrin repeat domain 46
chr12_+_128399917 0.04 ENST00000544645.1
LINC00507
long intergenic non-protein coding RNA 507
chr11_-_128894053 0.04 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr20_+_42136308 0.04 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr12_+_26164645 0.04 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_-_2751146 0.04 ENST00000268446.5
ENST00000274643.7
MYLK4
myosin light chain kinase family, member 4
chr22_+_39795746 0.03 ENST00000216160.6
ENST00000331454.3
TAB1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr2_+_106468204 0.03 ENST00000425756.1
ENST00000393349.2
NCK2
NCK adaptor protein 2
chr14_+_50291993 0.03 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr12_+_125811162 0.03 ENST00000299308.3
TMEM132B
transmembrane protein 132B
chr12_-_71182695 0.03 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_-_134326009 0.03 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr7_+_39125365 0.03 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chr9_+_99690592 0.03 ENST00000354649.3
NUTM2G
NUT family member 2G
chr9_+_12693336 0.03 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr4_-_100212132 0.03 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr13_-_38172863 0.03 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr1_-_115259337 0.03 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr6_-_135271219 0.03 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr1_-_217804377 0.03 ENST00000366935.3
ENST00000366934.3
GPATCH2
G patch domain containing 2
chr2_+_27255806 0.03 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chrX_+_1710484 0.03 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr12_+_25205568 0.02 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr10_-_101945771 0.02 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr4_+_90823130 0.02 ENST00000508372.1
MMRN1
multimerin 1
chr3_+_156799587 0.02 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr2_-_151344172 0.02 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr15_+_69857515 0.02 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr13_+_21714913 0.02 ENST00000450573.1
ENST00000467636.1
SAP18
Sin3A-associated protein, 18kDa
chr13_+_49551020 0.02 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:2000619 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0070884 calcineurin-NFAT signaling cascade(GO:0033173) regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.6 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.4 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation