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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HNF1A_HNF1B

Z-value: 0.95

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
ENSG00000135100.13 HNF1 homeobox A
ENSG00000108753.8 HNF1 homeobox B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF1Ahg19_v2_chr12_+_121416437_121416479-0.393.1e-02Click!

Activity profile of HNF1A_HNF1B motif

Sorted Z-values of HNF1A_HNF1B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_110723134 4.26 ENST00000510800.1
ENST00000512148.1
complement factor I
chr4_-_110723194 4.25 ENST00000394635.3
complement factor I
chr4_-_110723335 3.89 ENST00000394634.2
complement factor I
chrX_-_15619076 2.66 ENST00000252519.3
angiotensin I converting enzyme 2
chr19_+_50016610 2.57 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr5_-_35195338 2.46 ENST00000509839.1
prolactin receptor
chr3_-_74570291 1.83 ENST00000263665.6
contactin 3 (plasmacytoma associated)
chr20_-_7921090 1.74 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr17_-_202579 1.68 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
rabphilin 3A-like (without C2 domains)
chr16_+_20775358 1.66 ENST00000440284.2
acyl-CoA synthetase medium-chain family member 3
chr17_+_4692230 1.63 ENST00000331264.7
glycolipid transfer protein domain containing 2
chr19_+_50016411 1.62 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr7_+_141695671 1.52 ENST00000497673.1
ENST00000475668.2
maltase-glucoamylase (alpha-glucosidase)
chr7_+_141695633 1.51 ENST00000549489.2
maltase-glucoamylase (alpha-glucosidase)
chr22_+_31003133 1.49 ENST00000405742.3
transcobalamin II
chr6_-_29013017 1.47 ENST00000377175.1
olfactory receptor, family 2, subfamily W, member 1
chr22_+_31003190 1.44 ENST00000407817.3
transcobalamin II
chr14_-_94854926 1.36 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr7_-_50633078 1.36 ENST00000444124.2
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr8_-_95220775 1.35 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr22_-_32651326 1.35 ENST00000266086.4
solute carrier family 5 (glucose activated ion channel), member 4
chr22_+_31002779 1.34 ENST00000215838.3
transcobalamin II
chr1_+_162351503 1.29 ENST00000458626.2
chromosome 1 open reading frame 226
chr13_+_96085847 1.23 ENST00000376873.3
claudin 10
chr1_+_18807424 1.18 ENST00000400664.1
kelch domain containing 7A
chrX_-_105282712 1.08 ENST00000372563.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr12_+_109785708 1.01 ENST00000310903.5
myosin IH
chr17_+_26800756 1.00 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_+_35732955 0.99 ENST00000300618.4
chromosome 17 open reading frame 78
chr17_+_26800648 0.99 ENST00000545060.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_+_35732916 0.97 ENST00000586700.1
chromosome 17 open reading frame 78
chr17_+_26800296 0.93 ENST00000444914.3
ENST00000314669.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr22_-_30968813 0.92 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
galactose-3-O-sulfotransferase 1
chr13_-_103719196 0.91 ENST00000245312.3
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr17_+_68071458 0.88 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_68071389 0.86 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr16_+_21244986 0.81 ENST00000311620.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr3_-_157221380 0.80 ENST00000468233.1
ventricular zone expressed PH domain-containing 1
chr12_-_91574142 0.78 ENST00000547937.1
decorin
chr9_-_123812542 0.76 ENST00000223642.1
complement component 5
chr3_-_157221357 0.73 ENST00000494677.1
ventricular zone expressed PH domain-containing 1
chr5_-_61031495 0.72 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
chr1_+_104293028 0.72 ENST00000370079.3
amylase, alpha 1C (salivary)
chr16_-_55909255 0.70 ENST00000290567.9
carboxylesterase 5A
chr16_-_55909272 0.70 ENST00000319165.9
carboxylesterase 5A
chr16_-_55909211 0.70 ENST00000520435.1
carboxylesterase 5A
chr6_-_25930819 0.69 ENST00000360488.3
solute carrier family 17, member 2
chr6_-_25930904 0.64 ENST00000377850.3
solute carrier family 17, member 2
chr1_-_197036364 0.63 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr17_-_26733179 0.63 ENST00000440501.1
ENST00000321666.5
solute carrier family 46 (folate transporter), member 1
chr2_-_228244013 0.62 ENST00000304568.3
transmembrane 4 L six family member 20
chr8_-_87242589 0.61 ENST00000419776.2
ENST00000297524.3
solute carrier family 7 (anionic amino acid transporter), member 13
chr6_+_126070726 0.61 ENST00000368364.3
hes-related family bHLH transcription factor with YRPW motif 2
chr6_-_52628271 0.59 ENST00000493422.1
glutathione S-transferase alpha 2
chr6_-_51952418 0.57 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr1_-_168464875 0.57 ENST00000422253.1
RP5-968D22.3
chr16_-_57831914 0.56 ENST00000421376.2
kinesin family member C3
chr4_-_76944621 0.55 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr2_-_55920952 0.55 ENST00000447944.2
polyribonucleotide nucleotidyltransferase 1
chr1_+_104159999 0.55 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr10_+_45406627 0.54 ENST00000389583.4
transmembrane protein 72
chr6_+_54172653 0.54 ENST00000370869.3
tubulointerstitial nephritis antigen
chr6_-_51952367 0.52 ENST00000340994.4
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr2_+_38177575 0.49 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr10_-_61495760 0.48 ENST00000395347.1
solute carrier family 16, member 9
chr4_-_100212132 0.48 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr4_+_3443614 0.47 ENST00000382774.3
ENST00000511533.1
HGF activator
chr6_+_12717892 0.47 ENST00000379350.1
phosphatase and actin regulator 1
chr6_-_154751629 0.47 ENST00000424998.1
CNKSR family member 3
chr8_-_108510224 0.45 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr6_+_54173227 0.45 ENST00000259782.4
ENST00000370864.3
tubulointerstitial nephritis antigen
chr8_-_70745575 0.45 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr2_+_133174147 0.45 ENST00000329321.3
G protein-coupled receptor 39
chr11_-_65149422 0.44 ENST00000526432.1
ENST00000527174.1
solute carrier family 25, member 45
chr3_+_183948161 0.44 ENST00000426955.2
von Willebrand factor A domain containing 5B2
chr4_+_155484155 0.43 ENST00000509493.1
fibrinogen beta chain
chr4_-_70518941 0.42 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr2_-_158300556 0.42 ENST00000264192.3
cytohesin 1 interacting protein
chr3_-_137834436 0.41 ENST00000327532.2
ENST00000467030.1
DAZ interacting zinc finger protein 1-like
chr8_+_104892639 0.40 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr15_-_99057551 0.40 ENST00000558256.1
family with sequence similarity 169, member B
chr22_-_30970560 0.39 ENST00000402369.1
ENST00000406361.1
galactose-3-O-sulfotransferase 1
chr5_-_111093167 0.39 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr3_-_164796269 0.38 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr17_+_1646130 0.37 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr7_-_155601766 0.37 ENST00000430104.1
sonic hedgehog
chr1_+_207277590 0.37 ENST00000367070.3
complement component 4 binding protein, alpha
chr12_+_20963647 0.36 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr14_+_39703112 0.36 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr2_+_115219171 0.36 ENST00000409163.1
dipeptidyl-peptidase 10 (non-functional)
chr5_+_140571902 0.35 ENST00000239446.4
protocadherin beta 10
chr4_+_71494461 0.35 ENST00000396073.3
enamelin
chr6_+_131571535 0.34 ENST00000474850.2
A kinase (PRKA) anchor protein 7
chr16_-_69385681 0.34 ENST00000288025.3
transmembrane emp24 protein transport domain containing 6
chr12_+_20963632 0.33 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr19_+_41305085 0.33 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr17_+_79953310 0.31 ENST00000582355.2
alveolar soft part sarcoma chromosome region, candidate 1
chr11_+_46740730 0.31 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr1_-_42630389 0.31 ENST00000357001.2
guanylate cyclase activator 2A (guanylin)
chr8_+_21911054 0.31 ENST00000519850.1
ENST00000381470.3
dematin actin binding protein
chr4_-_1166954 0.31 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
spondin 2, extracellular matrix protein
chr9_-_94712434 0.31 ENST00000375708.3
receptor tyrosine kinase-like orphan receptor 2
chr19_+_11350278 0.31 ENST00000252453.8
chromosome 19 open reading frame 80
chr6_+_47624172 0.30 ENST00000507065.1
ENST00000296862.1
G protein-coupled receptor 111
chr16_-_57831676 0.30 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
kinesin family member C3
chr2_-_88427568 0.30 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr8_-_17752996 0.29 ENST00000381841.2
ENST00000427924.1
fibrinogen-like 1
chr9_+_130860583 0.29 ENST00000373064.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr1_-_110284384 0.27 ENST00000540225.1
glutathione S-transferase mu 3 (brain)
chr1_+_119911425 0.27 ENST00000361035.4
ENST00000325945.3
hydroxyacid oxidase 2 (long chain)
chr3_-_49466686 0.27 ENST00000273598.3
ENST00000436744.2
nicolin 1
chr6_-_25874440 0.27 ENST00000361703.6
ENST00000397060.4
solute carrier family 17 (organic anion transporter), member 3
chr11_+_560956 0.27 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr9_+_130860810 0.26 ENST00000433501.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr14_-_57960545 0.26 ENST00000526336.1
ENST00000216445.3
chromosome 14 open reading frame 105
chr12_-_8693469 0.25 ENST00000545274.1
ENST00000446457.2
C-type lectin domain family 4, member E
chr12_+_40787194 0.24 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr5_-_10761206 0.24 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr5_+_67586465 0.24 ENST00000336483.5
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_+_186383741 0.24 ENST00000232003.4
histidine-rich glycoprotein
chr12_-_39837192 0.22 ENST00000361961.3
ENST00000395670.3
kinesin family member 21A
chr7_-_47579188 0.21 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
tensin 3
chr12_+_100867486 0.21 ENST00000548884.1
nuclear receptor subfamily 1, group H, member 4
chr1_+_36789335 0.21 ENST00000373137.2
RP11-268J15.5
chr3_+_185431080 0.20 ENST00000296270.1
chromosome 3 open reading frame 65
chr2_-_47572105 0.20 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr3_-_169587621 0.20 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
leucine rich repeat containing 31
chr12_+_60058458 0.20 ENST00000548610.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr16_+_20775024 0.19 ENST00000289416.5
acyl-CoA synthetase medium-chain family member 3
chr11_-_117695449 0.19 ENST00000292079.2
FXYD domain containing ion transport regulator 2
chr12_+_100897130 0.19 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
nuclear receptor subfamily 1, group H, member 4
chr10_-_38146510 0.19 ENST00000395867.3
zinc finger protein 248
chr4_+_100495864 0.18 ENST00000265517.5
ENST00000422897.2
microsomal triglyceride transfer protein
chr11_-_128894053 0.18 ENST00000392657.3
Rho GTPase activating protein 32
chr4_-_987164 0.17 ENST00000398520.2
solute carrier family 26 (anion exchanger), member 1
chr2_-_162931052 0.17 ENST00000360534.3
dipeptidyl-peptidase 4
chr19_-_49565254 0.17 ENST00000593537.1
neurotrophin 4
chr6_-_116833500 0.17 ENST00000356128.4
trafficking protein particle complex 3-like
chr11_+_2405833 0.16 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr12_-_91546926 0.16 ENST00000550758.1
decorin
chr20_+_43029911 0.16 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
hepatocyte nuclear factor 4, alpha
chr22_-_38506619 0.15 ENST00000332536.5
ENST00000381669.3
BAI1-associated protein 2-like 2
chr16_-_15474904 0.15 ENST00000534094.1
nuclear pore complex interacting protein family, member A5
chr14_+_21156915 0.15 ENST00000397990.4
ENST00000555597.1
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_+_234668894 0.15 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_-_6098770 0.14 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr4_+_187187337 0.14 ENST00000492972.2
coagulation factor XI
chr14_+_95027772 0.14 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr9_+_82186872 0.13 ENST00000376544.3
ENST00000376520.4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr10_-_128359074 0.13 ENST00000544758.1
chromosome 10 open reading frame 90
chr4_+_159443090 0.13 ENST00000343542.5
ENST00000470033.1
relaxin/insulin-like family peptide receptor 1
chr11_+_64358686 0.13 ENST00000473690.1
solute carrier family 22 (organic anion/urate transporter), member 12
chr10_+_111765562 0.12 ENST00000360162.3
adducin 3 (gamma)
chr4_-_74486109 0.12 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr12_-_76879852 0.12 ENST00000548341.1
oxysterol binding protein-like 8
chr17_+_41052808 0.11 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
glucose-6-phosphatase, catalytic subunit
chr18_+_5748793 0.11 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
chr19_-_42133420 0.11 ENST00000221954.2
ENST00000600925.1
carcinoembryonic antigen-related cell adhesion molecule 4
chr11_-_111649015 0.11 ENST00000529841.1
RP11-108O10.2
chr6_-_161085291 0.11 ENST00000316300.5
lipoprotein, Lp(a)
chr11_-_83393457 0.11 ENST00000404783.3
discs, large homolog 2 (Drosophila)
chr4_-_74486347 0.11 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr3_+_180319918 0.10 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
tetratricopeptide repeat domain 14
chr3_+_66271410 0.10 ENST00000336733.6
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr13_+_27825706 0.10 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
ribosomal protein L21
chr2_+_109223595 0.10 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr4_-_166034029 0.10 ENST00000306480.6
transmembrane protein 192
chr4_+_74269956 0.10 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr17_+_48823896 0.10 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr10_-_52645379 0.09 ENST00000395489.2
APOBEC1 complementation factor
chr5_+_140772381 0.09 ENST00000398604.2
protocadherin gamma subfamily A, 8
chr3_+_75955817 0.09 ENST00000487694.3
ENST00000602589.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr6_+_25754927 0.09 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr1_-_159684371 0.08 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
C-reactive protein, pentraxin-related
chr7_-_87856280 0.08 ENST00000490437.1
ENST00000431660.1
sorcin
chr8_-_87755878 0.08 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chr7_-_87856303 0.08 ENST00000394641.3
sorcin
chr7_+_152456829 0.08 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ARP3 actin-related protein 3 homolog B (yeast)
chr16_-_20587599 0.08 ENST00000566384.1
ENST00000565232.1
ENST00000567001.1
ENST00000565322.1
ENST00000569344.1
ENST00000329697.6
ENST00000414188.2
ENST00000568882.1
acyl-CoA synthetase medium-chain family member 2B
chrX_+_36254051 0.07 ENST00000378657.4
chromosome X open reading frame 30
chr10_-_72648541 0.07 ENST00000299299.3
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr10_-_52645416 0.07 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
APOBEC1 complementation factor
chr11_+_20620946 0.07 ENST00000525748.1
solute carrier family 6 (neurotransmitter transporter), member 5
chr22_+_32439019 0.07 ENST00000266088.4
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_+_24590560 0.07 ENST00000558325.1
RP11-468E2.6
chr12_+_100867694 0.07 ENST00000392986.3
ENST00000549996.1
nuclear receptor subfamily 1, group H, member 4
chr2_+_234637754 0.07 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_+_42873548 0.07 ENST00000533338.1
ENST00000534420.1
hook microtubule-tethering protein 3
Uncharacterized protein
chr9_+_82186682 0.06 ENST00000376552.2
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_+_76540386 0.06 ENST00000328299.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr4_-_102267953 0.06 ENST00000523694.2
ENST00000507176.1
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_107596910 0.05 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chr2_+_234526272 0.05 ENST00000373450.4
UDP glucuronosyltransferase 1 family, polypeptide A8
chr16_+_89696692 0.05 ENST00000261615.4
dipeptidase 1 (renal)
chr20_+_57414743 0.05 ENST00000313949.7
GNAS complex locus
chr16_+_20462783 0.05 ENST00000574251.1
ENST00000576361.1
ENST00000417235.2
ENST00000573854.1
ENST00000424070.1
ENST00000536134.1
ENST00000219054.6
ENST00000575690.1
ENST00000571894.1
acyl-CoA synthetase medium-chain family member 2A
chr18_-_48346415 0.05 ENST00000431965.2
ENST00000436348.2
maestro
chr3_+_107318157 0.05 ENST00000406780.1
bobby sox homolog (Drosophila)
chr2_+_234627424 0.04 ENST00000373409.3
UDP glucuronosyltransferase 1 family, polypeptide A4
chr12_-_102874378 0.04 ENST00000456098.1
insulin-like growth factor 1 (somatomedin C)

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0000023 maltose metabolic process(GO:0000023)
0.5 2.7 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.5 4.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.5 1.4 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.4 4.3 GO:0015889 cobalamin transport(GO:0015889)
0.4 2.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.3 1.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.3 0.8 GO:1904106 protein localization to microvillus(GO:1904106)
0.2 0.6 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 1.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.5 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.2 0.6 GO:0051958 methotrexate transport(GO:0051958)
0.2 0.5 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 13.2 GO:0030449 regulation of complement activation(GO:0030449)
0.1 1.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 1.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950) regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.0 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 1.3 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.5 GO:0015866 ADP transport(GO:0015866)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.5 GO:0006069 ethanol oxidation(GO:0006069)
0.0 1.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 1.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.4 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 2.3 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.6 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 2.0 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.9 GO:0005915 zonula adherens(GO:0005915)
0.1 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0036028 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 2.5 GO:0031904 endosome lumen(GO:0031904)
0.0 2.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 4.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0034358 protein-lipid complex(GO:0032994) plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 2.8 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.9 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0019770 IgG receptor activity(GO:0019770)
1.0 2.9 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.9 3.6 GO:0016160 amylase activity(GO:0016160)
0.7 2.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5 2.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 4.3 GO:0031419 cobalamin binding(GO:0031419)
0.4 2.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.3 1.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.2 2.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 13.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 0.6 GO:0015350 methotrexate transporter activity(GO:0015350)
0.2 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.2 1.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.1 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.9 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.5 12.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis