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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HNF4A

Z-value: 0.51

Motif logo

Transcription factors associated with HNF4A

Gene Symbol Gene ID Gene Info
ENSG00000101076.12 hepatocyte nuclear factor 4 alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ahg19_v2_chr20_+_42984330_42984445-0.154.2e-01Click!

Activity profile of HNF4A motif

Sorted Z-values of HNF4A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_61513146 1.78 ENST00000430431.1
long intergenic non-protein coding RNA 948
chr20_-_7921090 1.61 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr10_-_61513201 1.51 ENST00000414264.1
ENST00000594536.1
long intergenic non-protein coding RNA 948
chr19_+_41594377 1.29 ENST00000330436.3
cytochrome P450, family 2, subfamily A, polypeptide 13
chr2_-_28113217 1.18 ENST00000444339.2
ribokinase
chr11_+_60467047 1.03 ENST00000300226.2
membrane-spanning 4-domains, subfamily A, member 8
chr12_+_56075330 1.03 ENST00000394252.3
methyltransferase like 7B
chr2_-_159313214 0.88 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
coiled-coil domain containing 148
chr6_+_116937636 0.82 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
radial spoke head 4 homolog A (Chlamydomonas)
chr10_-_17171817 0.70 ENST00000377833.4
cubilin (intrinsic factor-cobalamin receptor)
chr19_+_4639514 0.69 ENST00000327473.4
tumor necrosis factor, alpha-induced protein 8-like 1
chr16_-_16317321 0.65 ENST00000205557.7
ENST00000575728.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr10_+_96522361 0.61 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr5_-_16509101 0.56 ENST00000399793.2
family with sequence similarity 134, member B
chr1_-_177939348 0.56 ENST00000464631.2
SEC16 homolog B (S. cerevisiae)
chr17_+_7591639 0.51 ENST00000396463.2
WD repeat containing, antisense to TP53
chr17_+_7591747 0.50 ENST00000534050.1
WD repeat containing, antisense to TP53
chr11_+_63137251 0.50 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr14_+_23352374 0.50 ENST00000267396.4
ENST00000536884.1
RAS (RAD and GEM)-like GTP binding 2
chr10_+_96698406 0.48 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chr2_+_241544834 0.48 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
G protein-coupled receptor 35
chr1_-_43751230 0.40 ENST00000523677.1
chromosome 1 open reading frame 210
chr7_+_120628731 0.39 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr2_+_74648848 0.39 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WD repeat domain 54
chr10_+_96443204 0.33 ENST00000339022.5
cytochrome P450, family 2, subfamily C, polypeptide 18
chr15_-_41120896 0.33 ENST00000299174.5
ENST00000427255.2
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr14_-_76447336 0.31 ENST00000556285.1
transforming growth factor, beta 3
chr17_-_38256973 0.30 ENST00000246672.3
nuclear receptor subfamily 1, group D, member 1
chr16_+_19429018 0.30 ENST00000542583.2
transmembrane channel-like 5
chr1_-_197036364 0.30 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr11_+_118868830 0.30 ENST00000334418.1
coiled-coil domain containing 84
chr10_+_96443378 0.30 ENST00000285979.6
cytochrome P450, family 2, subfamily C, polypeptide 18
chr1_-_155270770 0.29 ENST00000392414.3
pyruvate kinase, liver and RBC
chr19_+_45449301 0.28 ENST00000591597.1
apolipoprotein C-II
chr14_-_76447494 0.28 ENST00000238682.3
transforming growth factor, beta 3
chr5_+_79950463 0.28 ENST00000265081.6
mutS homolog 3
chr14_+_100485712 0.28 ENST00000544450.2
Enah/Vasp-like
chr11_-_123756334 0.27 ENST00000528595.1
ENST00000375026.2
transmembrane protein 225
chrX_+_38211777 0.26 ENST00000039007.4
ornithine carbamoyltransferase
chr1_+_196857144 0.26 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr2_+_219433281 0.25 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr11_+_1856034 0.25 ENST00000341958.3
synaptotagmin VIII
chr20_-_44485835 0.25 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
acyl-CoA thioesterase 8
chr12_-_39837192 0.24 ENST00000361961.3
ENST00000395670.3
kinesin family member 21A
chr22_-_31063782 0.24 ENST00000404885.1
ENST00000403268.1
ENST00000407308.1
ENST00000342474.4
ENST00000334679.3
dual specificity phosphatase 18
chr2_-_219433014 0.24 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr11_+_1855645 0.24 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr3_-_194072019 0.23 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chr9_-_116065551 0.23 ENST00000297894.5
ring finger protein 183
chr17_-_7082668 0.21 ENST00000573083.1
ENST00000574388.1
asialoglycoprotein receptor 1
chr16_-_3350614 0.21 ENST00000268674.2
tigger transposable element derived 7
chr19_-_10687907 0.21 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr1_+_78511586 0.21 ENST00000370759.3
GIPC PDZ domain containing family, member 2
chr11_-_10315741 0.20 ENST00000256190.8
SET binding factor 2
chr3_-_158390282 0.20 ENST00000264265.3
latexin
chr5_-_35048047 0.19 ENST00000231420.6
alanine--glyoxylate aminotransferase 2
chr11_-_64660916 0.19 ENST00000413053.1
microRNA 194-2
chr19_-_48867291 0.19 ENST00000435956.3
transmembrane protein 143
chr3_+_123813509 0.19 ENST00000460856.1
ENST00000240874.3
kalirin, RhoGEF kinase
chr11_-_32456891 0.19 ENST00000452863.3
Wilms tumor 1
chr1_+_6508100 0.18 ENST00000461727.1
espin
chr20_+_57875457 0.18 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
endothelin 3
chr6_+_46761118 0.18 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr17_+_4675175 0.18 ENST00000270560.3
transmembrane 4 L six family member 5
chr1_+_43855560 0.17 ENST00000562955.1
seizure threshold 2 homolog (mouse)
chr6_-_86099898 0.17 ENST00000455071.1
RP11-30P6.6
chr9_+_27109133 0.17 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr10_-_116444371 0.16 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr6_+_30131318 0.16 ENST00000376688.1
tripartite motif containing 15
chr1_+_241695424 0.16 ENST00000366558.3
ENST00000366559.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_-_120225600 0.15 ENST00000399075.4
chromosome 4 open reading frame 3
chr2_+_159313452 0.15 ENST00000389757.3
ENST00000389759.3
plakophilin 4
chr2_-_62733476 0.15 ENST00000335390.5
transmembrane protein 17
chr6_-_31926629 0.15 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chr16_+_24857162 0.15 ENST00000347898.3
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr16_-_88752889 0.15 ENST00000332281.5
snail family zinc finger 3
chr13_+_50656307 0.14 ENST00000378180.4
deleted in lymphocytic leukemia 1 (non-protein coding)
chr1_-_177939041 0.14 ENST00000308284.6
SEC16 homolog B (S. cerevisiae)
chr1_-_60392452 0.14 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr16_+_24857552 0.14 ENST00000568579.1
ENST00000567758.1
ENST00000569071.1
ENST00000539472.1
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr1_+_180601139 0.14 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr19_-_48867171 0.14 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
transmembrane protein 143
chr10_-_96829246 0.14 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr16_+_24857309 0.14 ENST00000565769.1
ENST00000449109.2
ENST00000424767.2
ENST00000545376.1
ENST00000569520.1
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr20_+_56136136 0.14 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr14_+_77648167 0.13 ENST00000554346.1
ENST00000298351.4
transmembrane protein 63C
chr22_+_25003606 0.13 ENST00000432867.1
gamma-glutamyltransferase 1
chr17_+_27369918 0.13 ENST00000323372.4
pipecolic acid oxidase
chr17_+_41857793 0.13 ENST00000449302.3
chromosome 17 open reading frame 105
chr11_-_73720276 0.13 ENST00000348534.4
uncoupling protein 3 (mitochondrial, proton carrier)
chr3_+_63897605 0.13 ENST00000487717.1
ataxin 7
chr6_+_30130969 0.12 ENST00000376694.4
tripartite motif containing 15
chr5_+_133842243 0.12 ENST00000515627.2
AC005355.2
chr6_+_31982539 0.12 ENST00000435363.2
ENST00000425700.2
complement component 4B (Chido blood group)
chrX_+_118108571 0.11 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr19_+_46806856 0.11 ENST00000300862.3
hypoxia inducible factor 3, alpha subunit
chr19_+_45449228 0.11 ENST00000252490.4
apolipoprotein C-II
chr2_+_219433588 0.11 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr3_+_108541545 0.11 ENST00000295756.6
T cell receptor associated transmembrane adaptor 1
chr9_+_139839686 0.11 ENST00000371634.2
complement component 8, gamma polypeptide
chr7_-_37956409 0.11 ENST00000436072.2
secreted frizzled-related protein 4
chr3_+_108541608 0.10 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chrX_+_66764375 0.10 ENST00000374690.3
androgen receptor
chr1_-_15911510 0.10 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chr15_-_73925651 0.10 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
neuroplastin
chr20_-_3644046 0.10 ENST00000290417.2
ENST00000319242.3
GDNF family receptor alpha 4
chr12_+_109273806 0.10 ENST00000228476.3
ENST00000547768.1
D-amino-acid oxidase
chr1_+_241695670 0.10 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr17_+_77704681 0.10 ENST00000328313.5
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr20_+_57875658 0.10 ENST00000371025.3
endothelin 3
chr9_+_139839711 0.09 ENST00000224181.3
complement component 8, gamma polypeptide
chr2_-_21266935 0.09 ENST00000233242.1
apolipoprotein B
chr6_-_29343068 0.09 ENST00000396806.3
olfactory receptor, family 12, subfamily D, member 3
chr12_+_56114189 0.09 ENST00000548082.1
retinol dehydrogenase 5 (11-cis/9-cis)
chr11_-_61658853 0.09 ENST00000525588.1
ENST00000540820.1
fatty acid desaturase 3
chr8_+_104831554 0.09 ENST00000408894.2
regulating synaptic membrane exocytosis 2
chr2_-_11810284 0.09 ENST00000306928.5
neurotensin receptor 2
chr3_+_124303539 0.09 ENST00000428018.2
kalirin, RhoGEF kinase
chr13_+_76334498 0.08 ENST00000534657.1
LIM domain 7
chr6_+_31949801 0.08 ENST00000428956.2
ENST00000498271.1
complement component 4A (Rodgers blood group)
chr17_+_4853442 0.08 ENST00000522301.1
enolase 3 (beta, muscle)
chr19_-_10687983 0.08 ENST00000587069.1
adaptor-related protein complex 1, mu 2 subunit
chr15_+_81489213 0.08 ENST00000559383.1
ENST00000394660.2
interleukin 16
chr3_-_187009798 0.08 ENST00000337774.5
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr17_+_44039704 0.08 ENST00000420682.2
ENST00000415613.2
ENST00000571987.1
ENST00000574436.1
ENST00000431008.3
microtubule-associated protein tau
chr22_+_25003568 0.08 ENST00000447416.1
gamma-glutamyltransferase 1
chr12_-_46384334 0.08 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SR-related CTD-associated factor 11
chrX_+_65382433 0.08 ENST00000374727.3
hephaestin
chr11_+_64073699 0.07 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr12_+_56114151 0.07 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
retinol dehydrogenase 5 (11-cis/9-cis)
chr19_-_12886327 0.07 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
hook microtubule-tethering protein 2
chr3_-_124653579 0.07 ENST00000478191.1
ENST00000311075.3
mucin 13, cell surface associated
chr3_+_63898275 0.07 ENST00000538065.1
ataxin 7
chr3_-_49851313 0.07 ENST00000333486.3
ubiquitin-like modifier activating enzyme 7
chr10_+_70320413 0.07 ENST00000373644.4
tet methylcytosine dioxygenase 1
chr6_+_43028182 0.07 ENST00000394058.1
kinesin light chain 4
chr3_+_123813543 0.07 ENST00000360013.3
kalirin, RhoGEF kinase
chr19_-_10687948 0.06 ENST00000592285.1
adaptor-related protein complex 1, mu 2 subunit
chr17_+_61554413 0.06 ENST00000538928.1
ENST00000290866.4
ENST00000428043.1
angiotensin I converting enzyme
chrX_+_118108601 0.06 ENST00000371628.3
LON peptidase N-terminal domain and ring finger 3
chr5_-_32444828 0.06 ENST00000265069.8
zinc finger RNA binding protein
chr1_+_100435315 0.05 ENST00000370155.3
ENST00000465289.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr11_-_45939374 0.05 ENST00000533151.1
ENST00000241041.3
peroxisomal biogenesis factor 16
chr7_+_45928079 0.05 ENST00000468955.1
insulin-like growth factor binding protein 1
chr14_+_23790655 0.05 ENST00000397276.2
poly(A) binding protein, nuclear 1
chr20_+_57875758 0.05 ENST00000395654.3
endothelin 3
chr15_+_22382382 0.05 ENST00000328795.4
olfactory receptor, family 4, subfamily N, member 4
chr1_+_94883991 0.05 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr3_+_46538981 0.05 ENST00000296142.3
receptor (chemosensory) transporter protein 3
chr5_+_72469014 0.05 ENST00000296776.5
transmembrane protein 174
chr19_-_7698599 0.05 ENST00000311069.5
Purkinje cell protein 2
chr10_-_103815874 0.05 ENST00000370033.4
ENST00000311122.5
chromosome 10 open reading frame 76
chr12_+_67663056 0.05 ENST00000545606.1
cullin-associated and neddylation-dissociated 1
chr18_+_54318616 0.05 ENST00000254442.3
WD repeat domain 7
chr14_+_23790690 0.04 ENST00000556821.1
poly(A) binding protein, nuclear 1
chr13_+_52586517 0.04 ENST00000523764.1
ENST00000521508.1
ALG11, alpha-1,2-mannosyltransferase
chr9_-_27005686 0.04 ENST00000380055.5
leucine rich repeat containing 19
chr19_+_39881951 0.04 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
mediator complex subunit 29
chr7_+_45927956 0.04 ENST00000275525.3
ENST00000457280.1
insulin-like growth factor binding protein 1
chr17_+_41052808 0.04 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
glucose-6-phosphatase, catalytic subunit
chr18_+_54318566 0.04 ENST00000589935.1
ENST00000357574.3
WD repeat domain 7
chr9_-_15307200 0.04 ENST00000506891.1
ENST00000541445.1
ENST00000512701.2
ENST00000380850.4
ENST00000297615.5
ENST00000355694.2
tetratricopeptide repeat domain 39B
chr19_+_45449266 0.04 ENST00000592257.1
apolipoprotein C-II
chr1_-_43855479 0.04 ENST00000290663.6
ENST00000372457.4
mediator complex subunit 8
chr15_+_50716576 0.04 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
ubiquitin specific peptidase 8
chr3_-_141868357 0.04 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
transcription factor Dp-2 (E2F dimerization partner 2)
chr20_+_36661910 0.04 ENST00000373433.4
regulation of nuclear pre-mRNA domain containing 1B
chr6_+_143999072 0.04 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
phosphatase and actin regulator 2
chr6_-_149806105 0.04 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
zinc finger CCCH-type containing 12D
chr15_-_100273544 0.04 ENST00000409796.1
ENST00000545021.1
ENST00000344791.2
ENST00000332728.4
ENST00000450512.1
LysM, putative peptidoglycan-binding, domain containing 4
chr16_-_87970122 0.03 ENST00000309893.2
carbonic anhydrase VA, mitochondrial
chr17_-_2614927 0.03 ENST00000435359.1
clustered mitochondria (cluA/CLU1) homolog
chr13_+_76334567 0.03 ENST00000321797.8
LIM domain 7
chr12_-_7125770 0.03 ENST00000261407.4
lysophosphatidylcholine acyltransferase 3
chr1_-_161208013 0.03 ENST00000515452.1
ENST00000367983.4
nuclear receptor subfamily 1, group I, member 3
chr19_-_39881777 0.03 ENST00000595564.1
ENST00000221265.3
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr1_-_41131326 0.03 ENST00000372684.3
regulating synaptic membrane exocytosis 3
chr2_+_10442993 0.03 ENST00000423674.1
ENST00000307845.3
hippocalcin-like 1
chr20_+_44486246 0.03 ENST00000255152.2
ENST00000454862.2
zinc finger, SWIM-type containing 3
chr13_+_76334795 0.03 ENST00000526202.1
ENST00000465261.2
LIM domain 7
chr6_-_33385854 0.03 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr6_-_33385823 0.03 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr6_+_80341000 0.03 ENST00000369838.4
SH3 domain binding glutamic acid-rich protein like 2
chr15_-_101142401 0.03 ENST00000314742.8
lines homolog (Drosophila)
chr6_-_33385655 0.03 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr11_-_73720122 0.02 ENST00000426995.2
uncoupling protein 3 (mitochondrial, proton carrier)
chr5_-_42811986 0.02 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr2_-_219134822 0.02 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr12_-_51422017 0.02 ENST00000394904.3
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr14_+_64680854 0.02 ENST00000458046.2
spectrin repeat containing, nuclear envelope 2
chr10_+_52152766 0.02 ENST00000596442.1
Uncharacterized protein
chr1_-_161207953 0.02 ENST00000367982.4
nuclear receptor subfamily 1, group I, member 3
chr10_+_104404218 0.02 ENST00000302424.7
tripartite motif containing 8
chr7_+_192969 0.02 ENST00000313766.5
family with sequence similarity 20, member C
chr12_-_21757774 0.02 ENST00000261195.2
glycogen synthase 2 (liver)
chr6_+_31926857 0.02 ENST00000375394.2
ENST00000544581.1
superkiller viralicidic activity 2-like (S. cerevisiae)
chr1_-_167059830 0.02 ENST00000367868.3
glycoprotein A33 (transmembrane)
chr2_-_179914760 0.02 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
coiled-coil domain containing 141
chr8_+_96037205 0.02 ENST00000396124.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_+_121163538 0.02 ENST00000242592.4
acyl-CoA dehydrogenase, C-2 to C-3 short chain

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.2 1.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.2 1.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.6 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.2 1.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.2 1.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.3 GO:0070859 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.3 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.3 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.7 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.9 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
0.0 0.0 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0001534 radial spoke(GO:0001534)
0.1 0.3 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 2.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 3.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0000406 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 1.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.0 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism