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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for HNF4G
Z-value: 1.28
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Transcription factors associated with HNF4G
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HNF4G | hg19_v2_chr8_+_76452097_76452126 | 0.71 | 9.5e-06 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_41356347 Show fit | 14.45 |
ENST00000301141.5
|
cytochrome P450, family 2, subfamily A, polypeptide 6 |
|
| chr4_-_7044657 Show fit | 7.25 |
ENST00000310085.4
|
coiled-coil domain containing 96 |
|
| chr19_-_41388657 Show fit | 6.70 |
ENST00000301146.4
ENST00000291764.3 |
cytochrome P450, family 2, subfamily A, polypeptide 7 |
|
| chr21_+_42688657 Show fit | 6.66 |
ENST00000357985.2
|
family with sequence similarity 3, member B |
|
| chr5_+_94727048 Show fit | 6.59 |
ENST00000283357.5
|
family with sequence similarity 81, member B |
|
| chr4_-_16077741 Show fit | 6.36 |
ENST00000447510.2
ENST00000540805.1 ENST00000539194.1 |
prominin 1 |
|
| chr9_-_112970436 Show fit | 5.91 |
ENST00000400613.4
|
chromosome 9 open reading frame 152 |
|
| chr19_+_41594377 Show fit | 5.71 |
ENST00000330436.3
|
cytochrome P450, family 2, subfamily A, polypeptide 13 |
|
| chr14_+_105952648 Show fit | 5.67 |
ENST00000330233.7
|
cysteine-rich protein 1 (intestinal) |
|
| chr4_+_165675197 Show fit | 5.61 |
ENST00000515485.1
|
RP11-294O2.2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HNF4G
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.9 | 19.6 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 0.6 | 12.6 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 1.9 | 9.7 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.8 | 9.2 | GO:1904977 | lymphatic endothelial cell migration(GO:1904977) |
| 0.1 | 7.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 1.6 | 6.4 | GO:2000768 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 1.1 | 5.7 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 1.1 | 5.4 | GO:0009804 | coumarin metabolic process(GO:0009804) |
| 0.9 | 5.1 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 1.6 | 4.8 | GO:0033214 | iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 14.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 8.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 7.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.4 | 6.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 6.0 | GO:0030315 | T-tubule(GO:0030315) |
| 1.0 | 4.8 | GO:0098536 | deuterosome(GO:0098536) |
| 0.7 | 4.8 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 0.1 | 3.8 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 3.8 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 3.5 | GO:0001772 | immunological synapse(GO:0001772) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 32.8 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.1 | 7.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 7.0 | GO:0019003 | GDP binding(GO:0019003) |
| 0.6 | 6.5 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.1 | 6.2 | GO:0042805 | actinin binding(GO:0042805) |
| 0.3 | 5.7 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 5.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.9 | 5.2 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.1 | 5.1 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 4.8 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 8.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 5.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 4.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 2.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 2.2 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 1.6 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.5 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 1.5 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 1.4 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 25.8 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.2 | 8.1 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 6.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 3.9 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 3.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 3.4 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 3.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 3.1 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 3.0 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.2 | 2.3 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |