Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for HOXA2_HOXB1

Z-value: 0.59

Motif logo

logo of logo of

Transcription factors associated with HOXA2_HOXB1

Gene Symbol Gene ID Gene Info
HOXA2
ENSG00000105996.5 homeobox A2
HOXB1
ENSG00000120094.6 homeobox B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA2hg19_v2_chr7_-_27142290_271424300.106.2e-01Click!
HOXB1hg19_v2_chr17_-_46608272_46608385-0.057.8e-01Click!

Activity profile of HOXA2_HOXB1 motif

Sorted Z-values of HOXA2_HOXB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_151561085 2.71 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_151561506 2.49 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_2162162 1.36 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_-_190044480 1.26 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_-_111782484 1.12 ENST00000533971.1
CRYAB
crystallin, alpha B
chr15_-_74501360 1.05 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr1_-_205391178 1.05 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr4_-_90757364 0.88 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr11_-_111782696 0.87 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr3_-_51813009 0.85 ENST00000398780.3
IQCF6
IQ motif containing F6
chr4_-_90756769 0.80 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr17_+_37824700 0.77 ENST00000581428.1
PNMT
phenylethanolamine N-methyltransferase
chr17_-_46623441 0.74 ENST00000330070.4
HOXB2
homeobox B2
chr10_-_79397202 0.73 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_79397316 0.72 ENST00000372421.5
ENST00000457953.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_100995540 0.70 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chr1_-_182641367 0.66 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr12_+_21168630 0.66 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chrX_-_30993201 0.62 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr10_-_79397479 0.59 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_+_37824217 0.56 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr12_+_7023491 0.56 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr15_-_64673630 0.55 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr17_+_37824411 0.54 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr19_-_51512804 0.52 ENST00000594211.1
ENST00000376832.4
KLK9
kallikrein-related peptidase 9
chr8_-_143961236 0.50 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
CYP11B1
cytochrome P450, family 11, subfamily B, polypeptide 1
chr5_+_167181917 0.49 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr17_+_7758374 0.43 ENST00000301599.6
ENST00000574668.1
TMEM88
transmembrane protein 88
chr1_-_43833628 0.42 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr17_+_39975544 0.42 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr15_-_95870310 0.42 ENST00000508732.2
CTD-2536I1.1
CTD-2536I1.1
chr7_-_143956815 0.40 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr17_+_39975455 0.40 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr1_-_182642017 0.40 ENST00000367557.4
ENST00000258302.4
RGS8
regulator of G-protein signaling 8
chr10_-_100995603 0.39 ENST00000370552.3
ENST00000370549.1
HPSE2
heparanase 2
chr11_+_57365150 0.38 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr7_-_144107320 0.37 ENST00000483238.1
ENST00000467773.1
NOBOX
NOBOX oogenesis homeobox
chr2_-_154335300 0.36 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr12_+_101988627 0.36 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr9_+_132099158 0.35 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr10_-_98945515 0.34 ENST00000371070.4
SLIT1
slit homolog 1 (Drosophila)
chr17_-_27418537 0.34 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr12_-_15038779 0.33 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr9_-_127269661 0.32 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr20_+_52105495 0.32 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr12_+_57610562 0.31 ENST00000349394.5
NXPH4
neurexophilin 4
chr14_+_68189190 0.29 ENST00000539142.1
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr11_-_126870655 0.29 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr16_+_30080857 0.28 ENST00000565355.1
ALDOA
aldolase A, fructose-bisphosphate
chr12_+_101988774 0.28 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr7_-_86595190 0.28 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chrX_+_99899180 0.26 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr17_+_36584662 0.25 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr1_+_178062855 0.25 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr22_-_39151463 0.25 ENST00000405510.1
ENST00000433561.1
SUN2
Sad1 and UNC84 domain containing 2
chr2_-_197226875 0.24 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr9_+_124329336 0.24 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr3_+_189507432 0.24 ENST00000354600.5
TP63
tumor protein p63
chr3_+_189507523 0.23 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr7_-_150864635 0.23 ENST00000297537.4
GBX1
gastrulation brain homeobox 1
chr12_-_28124903 0.23 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr10_-_105615164 0.22 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr1_+_243419306 0.22 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8
serologically defined colon cancer antigen 8
chr18_+_56887381 0.22 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
GRP
gastrin-releasing peptide
chr7_-_27170352 0.21 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr17_+_43239191 0.21 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr14_-_81893734 0.21 ENST00000555447.1
STON2
stonin 2
chr17_-_37353950 0.21 ENST00000394310.3
ENST00000394303.3
ENST00000344140.5
CACNB1
calcium channel, voltage-dependent, beta 1 subunit
chr15_-_64673665 0.20 ENST00000300035.4
KIAA0101
KIAA0101
chr5_-_179045199 0.20 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr8_+_143530791 0.19 ENST00000517894.1
BAI1
brain-specific angiogenesis inhibitor 1
chr12_+_56414851 0.18 ENST00000547167.1
IKZF4
IKAROS family zinc finger 4 (Eos)
chr1_+_68150744 0.15 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr8_-_67874805 0.15 ENST00000563496.1
TCF24
transcription factor 24
chr17_-_1588101 0.14 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
PRPF8
pre-mRNA processing factor 8
chr7_+_20370746 0.14 ENST00000222573.4
ITGB8
integrin, beta 8
chr5_+_162864575 0.13 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr12_-_28125638 0.13 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr5_+_145826867 0.13 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr17_-_57229155 0.13 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr8_+_23386557 0.13 ENST00000523930.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr19_+_35849723 0.13 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr16_+_25703274 0.12 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr2_+_242089833 0.12 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr7_-_14029283 0.11 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr17_+_79495397 0.11 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr10_+_24755416 0.11 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr9_-_73029540 0.11 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr4_-_102267953 0.11 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_+_150264555 0.10 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr15_-_74501310 0.10 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr9_-_36276966 0.10 ENST00000543356.2
ENST00000396594.3
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr3_+_148545586 0.10 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr20_+_42574317 0.10 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr3_+_150264458 0.09 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr19_+_13051206 0.09 ENST00000586760.1
CALR
calreticulin
chr10_-_98945677 0.09 ENST00000266058.4
ENST00000371041.3
SLIT1
slit homolog 1 (Drosophila)
chr6_+_33387830 0.09 ENST00000293748.5
SYNGAP1
synaptic Ras GTPase activating protein 1
chr6_+_33388013 0.09 ENST00000449372.2
SYNGAP1
synaptic Ras GTPase activating protein 1
chr10_+_18689637 0.09 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr7_-_14029515 0.08 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr17_+_48609903 0.08 ENST00000268933.3
EPN3
epsin 3
chr12_+_57482877 0.08 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr1_-_109584768 0.07 ENST00000357672.3
WDR47
WD repeat domain 47
chr7_-_100881109 0.07 ENST00000308344.5
CLDN15
claudin 15
chr7_+_26591441 0.07 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2
AC004947.2
chr8_+_23386305 0.07 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr7_-_27142290 0.07 ENST00000222718.5
HOXA2
homeobox A2
chr12_-_86650077 0.07 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr20_+_34802295 0.07 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_68961934 0.07 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr12_+_10658489 0.07 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr6_+_50061315 0.06 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr1_-_108507631 0.06 ENST00000527011.1
ENST00000370056.4
VAV3
vav 3 guanine nucleotide exchange factor
chr1_-_109584716 0.06 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WDR47
WD repeat domain 47
chr2_-_145277882 0.06 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2
chr1_-_109584608 0.06 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr12_-_57472522 0.05 ENST00000379391.3
ENST00000300128.4
TMEM194A
transmembrane protein 194A
chr9_-_101471479 0.05 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr2_+_68961905 0.05 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr6_-_112575912 0.04 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chrX_-_110655391 0.04 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chrX_+_41583408 0.04 ENST00000302548.4
GPR82
G protein-coupled receptor 82
chr20_+_34742650 0.04 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr7_-_27135591 0.04 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr14_+_22985251 0.03 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr19_+_52074502 0.03 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175
zinc finger protein 175
chr20_+_30467600 0.02 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr9_+_113431059 0.02 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr12_-_88423164 0.02 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr9_-_26947453 0.02 ENST00000397292.3
PLAA
phospholipase A2-activating protein
chr15_+_48009541 0.01 ENST00000536845.2
ENST00000558816.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr9_-_73477826 0.01 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr3_+_191046810 0.00 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr6_+_29426230 0.00 ENST00000442615.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr12_-_58135903 0.00 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr2_-_49381572 0.00 ENST00000454032.1
ENST00000304421.4
FSHR
follicle stimulating hormone receptor
chrX_-_45629661 0.00 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr16_-_49890016 0.00 ENST00000563137.2
ZNF423
zinc finger protein 423
chrX_-_47509887 0.00 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1
ELK1, member of ETS oncogene family
chr14_-_21516590 0.00 ENST00000555026.1
NDRG2
NDRG family member 2
chrY_+_26997726 0.00 ENST00000382296.2
DAZ4
deleted in azoospermia 4
chr11_+_68228186 0.00 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3
protein phosphatase 6, regulatory subunit 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA2_HOXB1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 5.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.7 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 0.8 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 0.8 GO:0021569 rhombomere 3 development(GO:0021569)
0.2 1.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 2.0 GO:0034465 response to carbon monoxide(GO:0034465)
0.2 1.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 2.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 0.3 GO:0007538 primary sex determination(GO:0007538)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.5 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 1.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0019230 proprioception(GO:0019230)
0.0 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.3 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.8 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 5.1 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.3 1.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 5.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.1 GO:0030305 heparanase activity(GO:0030305)
0.3 2.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 0.5 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.6 GO:0031432 titin binding(GO:0031432)
0.0 1.2 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis