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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXA4

Z-value: 0.45

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Transcription factors associated with HOXA4

Gene Symbol Gene ID Gene Info
HOXA4
ENSG00000197576.9 homeobox A4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA4hg19_v2_chr7_-_27170352_27170418-0.479.6e-03Click!

Activity profile of HOXA4 motif

Sorted Z-values of HOXA4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39211463 1.21 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr10_+_77056134 1.03 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr2_+_128403720 0.70 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr2_+_128403439 0.69 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr9_+_75263565 0.64 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr11_-_69633792 0.59 ENST00000334134.2
FGF3
fibroblast growth factor 3
chr19_+_45409011 0.54 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr2_-_69098566 0.52 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr4_+_84457250 0.49 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr4_+_84457529 0.48 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr3_+_159557637 0.47 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr10_-_92681033 0.45 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr8_-_95449155 0.44 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr8_+_22424551 0.42 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chrX_+_41548220 0.41 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr8_-_10512569 0.41 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chrX_+_41548259 0.40 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr12_+_29376592 0.40 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr12_+_29376673 0.40 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr1_-_42384343 0.39 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr11_-_5364809 0.39 ENST00000300773.2
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr9_-_113761720 0.37 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr1_-_100643765 0.37 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr11_+_128563652 0.35 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_+_56521840 0.35 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr18_-_658244 0.34 ENST00000585033.1
ENST00000323813.3
C18orf56
chromosome 18 open reading frame 56
chr17_-_10452929 0.33 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr2_-_190927447 0.33 ENST00000260950.4
MSTN
myostatin
chr5_+_69321074 0.32 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B
small EDRK-rich factor 1B (centromeric)
chr2_+_54683419 0.31 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr7_+_7811992 0.31 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr5_+_66254698 0.31 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_-_67138015 0.31 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr3_-_178984759 0.30 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr7_+_144052381 0.29 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr11_+_128563948 0.29 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_66536248 0.29 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr2_-_105030466 0.28 ENST00000449772.1
AC068535.3
AC068535.3
chr17_+_37894570 0.28 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr19_-_51220176 0.28 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chrX_+_37639302 0.27 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr4_-_152147579 0.27 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chr12_-_86650045 0.27 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_+_12938541 0.26 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr1_+_151739131 0.25 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr8_+_39792474 0.25 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr7_-_29234802 0.25 ENST00000449801.1
ENST00000409850.1
CPVL
carboxypeptidase, vitellogenic-like
chr11_+_5372738 0.25 ENST00000380219.1
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr5_+_152870734 0.25 ENST00000521843.2
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr11_+_112832133 0.24 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr10_-_69455873 0.23 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr3_+_137490748 0.23 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr10_-_105845674 0.23 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr2_-_145278475 0.22 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr19_+_12949251 0.22 ENST00000251472.4
MAST1
microtubule associated serine/threonine kinase 1
chr1_+_28586006 0.22 ENST00000253063.3
SESN2
sestrin 2
chr15_+_51669444 0.22 ENST00000396399.2
GLDN
gliomedin
chr12_+_106976678 0.21 ENST00000392842.1
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr5_+_152870287 0.21 ENST00000340592.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr7_-_14026123 0.20 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr16_+_6533380 0.20 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr9_-_113341985 0.20 ENST00000374469.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr10_-_101825151 0.20 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr14_+_37131058 0.20 ENST00000361487.6
PAX9
paired box 9
chr15_+_90744533 0.20 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr9_+_87284622 0.20 ENST00000395882.1
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr1_-_12677714 0.19 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr17_-_10325261 0.19 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr17_+_54230819 0.18 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr12_+_72058130 0.18 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr10_-_106240032 0.17 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr11_+_12766583 0.17 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_-_116447283 0.15 ENST00000452729.1
ENST00000243222.4
COL10A1
collagen, type X, alpha 1
chr11_-_62313090 0.15 ENST00000528508.1
ENST00000533365.1
AHNAK
AHNAK nucleoprotein
chr12_-_91398796 0.15 ENST00000261172.3
ENST00000551767.1
EPYC
epiphycan
chr7_+_107110488 0.15 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr13_-_84456527 0.15 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr18_-_28742813 0.15 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr17_-_56082455 0.14 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr7_-_14026063 0.14 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chrX_+_37639264 0.14 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr9_-_113342160 0.13 ENST00000401783.2
ENST00000374461.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr19_-_42806919 0.13 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr1_+_214161272 0.13 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chr5_+_60933634 0.13 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr7_-_14029283 0.12 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr18_+_3247779 0.12 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_-_14028488 0.12 ENST00000405358.4
ETV1
ets variant 1
chrX_-_55024967 0.12 ENST00000545676.1
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr11_-_13517565 0.12 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr22_+_26138108 0.11 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
MYO18B
myosin XVIIIB
chr12_-_11091862 0.11 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr11_+_112046190 0.11 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr10_-_95462265 0.11 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
FRA10AC1
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr13_-_46716969 0.10 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_121311966 0.10 ENST00000338040.4
FBXO40
F-box protein 40
chr2_-_43453734 0.10 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr15_+_75080883 0.10 ENST00000567571.1
CSK
c-src tyrosine kinase
chr5_+_133562095 0.10 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr6_-_117150198 0.09 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr2_+_53994927 0.08 ENST00000295304.4
CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
chr16_+_86229728 0.08 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr5_+_152870106 0.08 ENST00000285900.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr1_+_155658849 0.07 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
DAP3
death associated protein 3
chrX_-_119445306 0.07 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr18_+_28956740 0.07 ENST00000308128.4
ENST00000359747.4
DSG4
desmoglein 4
chr5_-_1882858 0.07 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr15_+_80351977 0.06 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr3_-_57233966 0.06 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr16_+_7382745 0.06 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_+_77593448 0.06 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr9_+_44867571 0.05 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr14_+_45605157 0.05 ENST00000542564.2
FANCM
Fanconi anemia, complementation group M
chr12_+_53818855 0.05 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr8_-_67090825 0.05 ENST00000276571.3
CRH
corticotropin releasing hormone
chr21_+_17909594 0.05 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chrX_-_119445263 0.05 ENST00000309720.5
TMEM255A
transmembrane protein 255A
chr8_-_139926236 0.05 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr11_-_40315640 0.04 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr6_+_50681541 0.04 ENST00000008391.3
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr17_-_39538550 0.04 ENST00000394001.1
KRT34
keratin 34
chr12_+_53848549 0.04 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr18_-_70532906 0.04 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr8_-_99954788 0.04 ENST00000523601.1
STK3
serine/threonine kinase 3
chr5_+_66300446 0.04 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr15_+_80351910 0.04 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr5_+_147582387 0.04 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr7_+_100273736 0.04 ENST00000412215.1
ENST00000393924.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chrX_+_134654540 0.03 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr21_+_17443521 0.03 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr10_-_33623310 0.03 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr21_+_17442799 0.03 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_+_152011628 0.03 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr2_+_177015950 0.03 ENST00000306324.3
HOXD4
homeobox D4
chr7_-_130598059 0.02 ENST00000432045.2
MIR29B1
microRNA 29a
chr11_+_22688150 0.02 ENST00000454584.2
GAS2
growth arrest-specific 2
chr13_-_53422640 0.02 ENST00000338862.4
ENST00000377942.3
PCDH8
protocadherin 8
chr21_+_17443434 0.02 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr2_-_80531824 0.02 ENST00000295057.3
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr12_+_27677085 0.02 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr8_-_141774467 0.02 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr3_+_108855558 0.01 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
RP11-59E19.1
chr14_-_80697396 0.01 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr4_-_109541539 0.01 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr8_+_77593474 0.01 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr18_+_13612613 0.00 ENST00000586765.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr1_+_81771806 0.00 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr2_-_80531399 0.00 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.3 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.3 GO:0050894 determination of affect(GO:0050894)
0.1 1.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0071314 negative regulation of glucagon secretion(GO:0070093) cellular response to cocaine(GO:0071314) positive regulation of corticosterone secretion(GO:2000854)
0.0 0.6 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.5 GO:0044308 axonal spine(GO:0044308)
0.1 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.3 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.4 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation