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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXB3

Z-value: 0.69

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
HOXB3
ENSG00000120093.7 homeobox B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB3hg19_v2_chr17_-_46667594_466676190.461.1e-02Click!

Activity profile of HOXB3 motif

Sorted Z-values of HOXB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_152486950 3.64 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr17_+_62223320 2.52 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr22_+_30792980 1.72 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr4_+_86525299 1.65 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr11_-_107729887 1.60 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr12_+_15699286 1.52 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr3_+_121774202 1.49 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr5_+_150639360 1.46 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr2_+_113816215 1.41 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr6_+_34204642 1.37 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr1_+_62439037 1.33 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr2_+_113816685 1.30 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr11_+_33061543 1.20 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr4_+_144354644 1.19 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr17_+_40610862 1.18 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_-_9683238 1.15 ENST00000571771.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr12_-_123187890 1.15 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr7_-_24797546 1.09 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5
deafness, autosomal dominant 5
chr12_-_123201337 1.07 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_-_10978957 1.06 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr3_+_136537911 1.06 ENST00000393079.3
SLC35G2
solute carrier family 35, member G2
chr3_+_136537816 1.04 ENST00000446465.2
SLC35G2
solute carrier family 35, member G2
chr2_+_28618532 1.04 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr4_-_69111401 1.01 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr8_+_27168988 1.01 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr7_+_142458507 1.00 ENST00000492062.1
PRSS1
protease, serine, 1 (trypsin 1)
chr7_-_100860851 1.00 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr1_+_16090914 0.97 ENST00000441801.2
FBLIM1
filamin binding LIM protein 1
chr19_-_36001113 0.97 ENST00000434389.1
DMKN
dermokine
chr8_+_22132847 0.90 ENST00000521356.1
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr22_-_30234218 0.87 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr8_-_49833978 0.87 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr2_-_112237835 0.85 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr11_-_118135160 0.83 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr2_+_105050794 0.82 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chrX_+_138612889 0.82 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr10_+_6779326 0.82 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr22_-_29107919 0.82 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr14_+_56584414 0.78 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr9_+_135937365 0.75 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr17_-_8113542 0.74 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr2_+_90077680 0.74 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr2_-_70780572 0.74 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr8_-_49834299 0.72 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr21_-_27423339 0.72 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr21_+_43823983 0.71 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr2_+_87769459 0.71 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr12_+_22778116 0.71 ENST00000538218.1
ETNK1
ethanolamine kinase 1
chr14_+_32798547 0.71 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr1_-_197115818 0.69 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr14_+_32798462 0.68 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr15_-_55562479 0.68 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr6_+_53883708 0.68 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chr6_+_47666275 0.68 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr9_+_125133315 0.67 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr5_+_115177178 0.67 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chrX_+_43515467 0.66 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr4_+_5526883 0.66 ENST00000195455.2
C4orf6
chromosome 4 open reading frame 6
chrX_+_85969626 0.65 ENST00000484479.1
DACH2
dachshund homolog 2 (Drosophila)
chr8_+_7801144 0.65 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr12_-_8088871 0.65 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr8_+_7783859 0.63 ENST00000400120.3
ZNF705B
zinc finger protein 705B
chr17_-_57229155 0.62 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr12_+_56521840 0.62 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr9_+_134165063 0.62 ENST00000372264.3
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr19_+_7895074 0.62 ENST00000270530.4
EVI5L
ecotropic viral integration site 5-like
chr2_-_101925055 0.62 ENST00000295317.3
RNF149
ring finger protein 149
chr19_-_3557570 0.61 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr6_+_130339710 0.61 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr2_+_143635222 0.60 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr9_+_124329336 0.60 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr3_-_185538849 0.59 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_209602156 0.59 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205HG
MIR205 host gene (non-protein coding)
chr15_-_55563072 0.58 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr2_+_143635067 0.58 ENST00000264170.4
KYNU
kynureninase
chr19_+_11071546 0.58 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr7_-_111032971 0.58 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr14_-_106494587 0.57 ENST00000390597.2
IGHV2-5
immunoglobulin heavy variable 2-5
chr17_-_27418537 0.57 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr10_-_4285923 0.57 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr7_+_129015484 0.56 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr11_+_65554493 0.56 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr19_+_50270219 0.55 ENST00000354293.5
ENST00000359032.5
AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr4_+_5527117 0.55 ENST00000505296.1
C4orf6
chromosome 4 open reading frame 6
chr19_+_9296279 0.55 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr12_+_20848486 0.54 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr5_-_22853429 0.54 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr15_-_101835110 0.53 ENST00000560496.1
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr2_+_65215604 0.53 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_+_160542870 0.53 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chrX_-_21676442 0.53 ENST00000379499.2
KLHL34
kelch-like family member 34
chr6_+_160542821 0.53 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr12_+_128399965 0.52 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr11_-_63439013 0.51 ENST00000398868.3
ATL3
atlastin GTPase 3
chr3_-_151047327 0.51 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr1_+_161691353 0.51 ENST00000367948.2
FCRLB
Fc receptor-like B
chr7_-_99277610 0.50 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr1_-_201140673 0.50 ENST00000367333.2
TMEM9
transmembrane protein 9
chr12_-_22063787 0.49 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr14_-_23058063 0.49 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1
defender against cell death 1
chr16_+_12059091 0.48 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr4_-_120243545 0.48 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr2_+_29336855 0.47 ENST00000404424.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr1_-_109935819 0.47 ENST00000538502.1
SORT1
sortilin 1
chr12_-_10022735 0.46 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr7_-_121944491 0.46 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr8_-_7243080 0.46 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr8_-_13134045 0.46 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr4_+_87515454 0.46 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr1_-_67266939 0.45 ENST00000304526.2
INSL5
insulin-like 5
chr2_+_187371440 0.45 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr16_+_12059050 0.44 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr3_+_114012819 0.44 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr3_+_121902511 0.43 ENST00000490131.1
CASR
calcium-sensing receptor
chr2_+_234637754 0.43 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_89999259 0.41 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr10_-_135379132 0.41 ENST00000343131.5
SYCE1
synaptonemal complex central element protein 1
chr1_+_155006300 0.41 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr18_-_44181442 0.40 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr1_-_207226313 0.40 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr4_-_109541539 0.40 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr3_+_43732362 0.39 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr1_+_46972668 0.39 ENST00000371956.4
ENST00000360032.3
DMBX1
diencephalon/mesencephalon homeobox 1
chr4_+_40198527 0.38 ENST00000381799.5
RHOH
ras homolog family member H
chr18_+_61554932 0.38 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_-_104827425 0.38 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr20_-_55100981 0.38 ENST00000243913.4
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr1_+_12834984 0.38 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr8_-_42623747 0.37 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr12_-_118797475 0.36 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr1_+_207226574 0.36 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr11_-_104817919 0.36 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chrX_+_37208540 0.35 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1
TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr19_+_43919058 0.35 ENST00000598265.1
TEX101
testis expressed 101
chr7_-_99764907 0.35 ENST00000413800.1
GAL3ST4
galactose-3-O-sulfotransferase 4
chr9_+_5231413 0.35 ENST00000239316.4
INSL4
insulin-like 4 (placenta)
chr11_+_63273811 0.35 ENST00000340246.5
LGALS12
lectin, galactoside-binding, soluble, 12
chr9_+_125132803 0.34 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_11682790 0.34 ENST00000389825.3
ENST00000381483.2
GREB1
growth regulation by estrogen in breast cancer 1
chr19_-_17366257 0.33 ENST00000594059.1
AC010646.3
Uncharacterized protein
chr12_+_112563303 0.33 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr4_-_8873531 0.33 ENST00000400677.3
HMX1
H6 family homeobox 1
chr6_-_82957433 0.33 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr4_+_123300121 0.32 ENST00000446706.1
ENST00000296513.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr2_+_138722028 0.32 ENST00000280096.5
HNMT
histamine N-methyltransferase
chrX_-_77225135 0.32 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr2_+_234545092 0.31 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr3_-_164796269 0.31 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr1_+_202317815 0.31 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr2_-_89160770 0.31 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr5_-_108063949 0.31 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr12_+_112563335 0.30 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr12_-_91451758 0.30 ENST00000266719.3
KERA
keratocan
chr17_+_48624450 0.30 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20
spermatogenesis associated 20
chr14_-_24711470 0.30 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr1_-_52870104 0.29 ENST00000371568.3
ORC1
origin recognition complex, subunit 1
chr8_-_30670384 0.28 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr12_+_20848377 0.28 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr2_+_27498289 0.28 ENST00000296097.3
ENST00000420191.1
DNAJC5G
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr9_+_470288 0.28 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr12_+_8309630 0.28 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr4_-_52883786 0.28 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chrX_+_37208521 0.28 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr4_-_10686475 0.27 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr3_+_97887544 0.27 ENST00000356526.2
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chr18_+_55888767 0.27 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr18_-_21891460 0.26 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr4_+_119199864 0.26 ENST00000602414.1
ENST00000602520.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr11_+_95523621 0.25 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr10_-_22292613 0.25 ENST00000376980.3
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr15_+_92006567 0.25 ENST00000554333.1
RP11-661P17.1
RP11-661P17.1
chr19_+_48949030 0.25 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr6_+_26501449 0.25 ENST00000244513.6
BTN1A1
butyrophilin, subfamily 1, member A1
chr6_+_26204825 0.25 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr19_+_49990811 0.25 ENST00000391857.4
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr2_+_196313239 0.24 ENST00000413290.1
AC064834.1
AC064834.1
chr17_+_46970134 0.24 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_+_74846230 0.24 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr8_+_22132810 0.24 ENST00000356766.6
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr17_-_33390667 0.24 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr15_-_101835414 0.24 ENST00000254193.6
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr2_+_89184868 0.24 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr1_+_186265399 0.23 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr3_-_151034734 0.23 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr17_+_46970178 0.23 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr9_-_132383055 0.23 ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr3_-_105588231 0.23 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr2_-_88125471 0.23 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr2_+_44502597 0.23 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr11_+_55578854 0.22 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr7_+_26331541 0.22 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr14_-_94942577 0.22 ENST00000424550.2
ENST00000337425.5
ENST00000546329.1
SERPINA9
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
chr4_+_119199904 0.22 ENST00000602483.1
ENST00000602819.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr8_-_141810634 0.22 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr16_-_2837949 0.21 ENST00000570702.1
PRSS33
protease, serine, 33
chr12_-_6740802 0.21 ENST00000431922.1
LPAR5
lysophosphatidic acid receptor 5
chr17_+_46970127 0.20 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chrX_-_102757802 0.20 ENST00000372633.1
RAB40A
RAB40A, member RAS oncogene family
chr1_+_197237352 0.20 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1
crumbs homolog 1 (Drosophila)
chr4_-_164534657 0.19 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 1.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 1.5 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.4 1.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 2.7 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.3 1.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 1.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 1.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.3 0.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3 1.0 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 1.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 0.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 1.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.6 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 0.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 0.6 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 1.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 1.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 1.1 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.7 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.8 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.5 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.6 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.6 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.6 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.4 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 1.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.2 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.9 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.4 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.1 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 1.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 1.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.7 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.7 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.1 GO:1904956 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 1.3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.5 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 2.0 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.9 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.0 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990923 PET complex(GO:1990923)
0.4 1.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 0.6 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.2 0.6 GO:1990032 parallel fiber(GO:1990032)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.7 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.5 GO:0043229 intracellular organelle(GO:0043229)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.6 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0012505 endomembrane system(GO:0012505)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 1.7 GO:0008431 vitamin E binding(GO:0008431)
0.3 1.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 1.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3 1.1 GO:0034584 piRNA binding(GO:0034584)
0.3 1.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.3 1.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 1.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 0.6 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 1.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.8 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.8 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 1.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0030395 lactose binding(GO:0030395)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.8 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.1 1.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.4 GO:0031489 myosin V binding(GO:0031489)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 1.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 5.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 4.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway