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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for HOXC10_HOXD13
Z-value: 1.22
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Transcription factors associated with HOXC10_HOXD13
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXC10
|
ENSG00000180818.4 | homeobox C10 |
|
HOXD13
|
ENSG00000128714.5 | homeobox D13 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXD13 | hg19_v2_chr2_+_176957619_176957619 | 0.80 | 1.1e-07 | Click! |
| HOXC10 | hg19_v2_chr12_+_54378923_54378970 | 0.05 | 7.9e-01 | Click! |
Activity profile of HOXC10_HOXD13 motif
Sorted Z-values of HOXC10_HOXD13 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_216300784 | 9.49 |
ENST00000421182.1
ENST00000432072.2 ENST00000323926.6 ENST00000336916.4 ENST00000357867.4 ENST00000359671.1 ENST00000346544.3 ENST00000345488.5 ENST00000357009.2 ENST00000446046.1 ENST00000356005.4 ENST00000443816.1 ENST00000426059.1 ENST00000354785.4 |
FN1
|
fibronectin 1 |
| chr5_+_7654057 | 8.13 |
ENST00000537121.1
|
ADCY2
|
adenylate cyclase 2 (brain) |
| chr12_-_52779433 | 7.99 |
ENST00000257951.3
|
KRT84
|
keratin 84 |
| chr1_+_84630645 | 6.61 |
ENST00000394839.2
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr1_+_116654376 | 5.69 |
ENST00000369500.3
|
MAB21L3
|
mab-21-like 3 (C. elegans) |
| chr2_-_190044480 | 5.59 |
ENST00000374866.3
|
COL5A2
|
collagen, type V, alpha 2 |
| chr1_-_152386732 | 5.03 |
ENST00000271835.3
|
CRNN
|
cornulin |
| chr20_+_37554955 | 4.25 |
ENST00000217429.4
|
FAM83D
|
family with sequence similarity 83, member D |
| chr2_-_216878305 | 4.14 |
ENST00000263268.6
|
MREG
|
melanoregulin |
| chr7_+_134464376 | 4.08 |
ENST00000454108.1
ENST00000361675.2 |
CALD1
|
caldesmon 1 |
| chr4_+_169013666 | 3.73 |
ENST00000359299.3
|
ANXA10
|
annexin A10 |
| chr1_+_152957707 | 3.72 |
ENST00000368762.1
|
SPRR1A
|
small proline-rich protein 1A |
| chr7_-_41742697 | 3.63 |
ENST00000242208.4
|
INHBA
|
inhibin, beta A |
| chrX_-_73072534 | 3.61 |
ENST00000429829.1
|
XIST
|
X inactive specific transcript (non-protein coding) |
| chr7_+_134464414 | 3.43 |
ENST00000361901.2
|
CALD1
|
caldesmon 1 |
| chr17_-_39553844 | 3.43 |
ENST00000251645.2
|
KRT31
|
keratin 31 |
| chr4_-_69111401 | 3.39 |
ENST00000332644.5
|
TMPRSS11B
|
transmembrane protease, serine 11B |
| chr4_+_69313145 | 3.36 |
ENST00000305363.4
|
TMPRSS11E
|
transmembrane protease, serine 11E |
| chr4_-_48018580 | 2.98 |
ENST00000514170.1
|
CNGA1
|
cyclic nucleotide gated channel alpha 1 |
| chr2_+_158114051 | 2.93 |
ENST00000259056.4
|
GALNT5
|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) |
| chr8_-_49834299 | 2.93 |
ENST00000396822.1
|
SNAI2
|
snail family zinc finger 2 |
| chr1_+_153003671 | 2.92 |
ENST00000307098.4
|
SPRR1B
|
small proline-rich protein 1B |
| chr17_-_39526052 | 2.90 |
ENST00000251646.3
|
KRT33B
|
keratin 33B |
| chr6_+_34204642 | 2.79 |
ENST00000347617.6
ENST00000401473.3 ENST00000311487.5 ENST00000447654.1 ENST00000395004.3 |
HMGA1
|
high mobility group AT-hook 1 |
| chr1_+_84630053 | 2.75 |
ENST00000394838.2
ENST00000370682.3 ENST00000432111.1 |
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chrX_-_107682702 | 2.75 |
ENST00000372216.4
|
COL4A6
|
collagen, type IV, alpha 6 |
| chr15_-_80263506 | 2.75 |
ENST00000335661.6
|
BCL2A1
|
BCL2-related protein A1 |
| chr18_-_12656715 | 2.74 |
ENST00000462226.1
ENST00000497844.2 ENST00000309836.5 ENST00000453447.2 |
SPIRE1
|
spire-type actin nucleation factor 1 |
| chr3_-_52090461 | 2.67 |
ENST00000296483.6
ENST00000495880.1 |
DUSP7
|
dual specificity phosphatase 7 |
| chr14_-_72458326 | 2.65 |
ENST00000542853.1
|
AC005477.1
|
AC005477.1 |
| chr9_+_105757590 | 2.65 |
ENST00000374798.3
ENST00000487798.1 |
CYLC2
|
cylicin, basic protein of sperm head cytoskeleton 2 |
| chr21_+_39644214 | 2.56 |
ENST00000438657.1
|
KCNJ15
|
potassium inwardly-rectifying channel, subfamily J, member 15 |
| chr12_-_95510743 | 2.56 |
ENST00000551521.1
|
FGD6
|
FYVE, RhoGEF and PH domain containing 6 |
| chr8_+_31497271 | 2.47 |
ENST00000520407.1
|
NRG1
|
neuregulin 1 |
| chr4_-_39033963 | 2.47 |
ENST00000381938.3
|
TMEM156
|
transmembrane protein 156 |
| chr1_+_209859510 | 2.42 |
ENST00000367028.2
ENST00000261465.1 |
HSD11B1
|
hydroxysteroid (11-beta) dehydrogenase 1 |
| chr7_+_134551583 | 2.39 |
ENST00000435928.1
|
CALD1
|
caldesmon 1 |
| chr4_-_68749699 | 2.36 |
ENST00000545541.1
|
TMPRSS11D
|
transmembrane protease, serine 11D |
| chr1_-_205419053 | 2.35 |
ENST00000367154.1
|
LEMD1
|
LEM domain containing 1 |
| chr1_+_62439037 | 2.30 |
ENST00000545929.1
|
INADL
|
InaD-like (Drosophila) |
| chr17_-_38859996 | 2.28 |
ENST00000264651.2
|
KRT24
|
keratin 24 |
| chr1_+_32042105 | 2.19 |
ENST00000457433.2
ENST00000441210.2 |
TINAGL1
|
tubulointerstitial nephritis antigen-like 1 |
| chr1_+_32042131 | 2.15 |
ENST00000271064.7
ENST00000537531.1 |
TINAGL1
|
tubulointerstitial nephritis antigen-like 1 |
| chr21_+_39644305 | 2.14 |
ENST00000398930.1
|
KCNJ15
|
potassium inwardly-rectifying channel, subfamily J, member 15 |
| chr12_-_91539918 | 2.12 |
ENST00000548218.1
|
DCN
|
decorin |
| chr6_+_12290586 | 2.11 |
ENST00000379375.5
|
EDN1
|
endothelin 1 |
| chr7_+_134576317 | 2.08 |
ENST00000424922.1
ENST00000495522.1 |
CALD1
|
caldesmon 1 |
| chr8_+_42873548 | 2.07 |
ENST00000533338.1
ENST00000534420.1 |
HOOK3
RP11-598P20.5
|
hook microtubule-tethering protein 3 Uncharacterized protein |
| chr1_+_17559776 | 2.03 |
ENST00000537499.1
ENST00000413717.2 ENST00000536552.1 |
PADI1
|
peptidyl arginine deiminase, type I |
| chr21_+_39644395 | 2.03 |
ENST00000398934.1
|
KCNJ15
|
potassium inwardly-rectifying channel, subfamily J, member 15 |
| chr4_+_86525299 | 2.02 |
ENST00000512201.1
|
ARHGAP24
|
Rho GTPase activating protein 24 |
| chr21_+_39644172 | 1.99 |
ENST00000398932.1
|
KCNJ15
|
potassium inwardly-rectifying channel, subfamily J, member 15 |
| chr2_+_210444142 | 1.98 |
ENST00000360351.4
ENST00000361559.4 |
MAP2
|
microtubule-associated protein 2 |
| chr9_-_95640218 | 1.98 |
ENST00000395506.3
ENST00000375495.3 ENST00000332591.6 |
ZNF484
|
zinc finger protein 484 |
| chr21_-_28217721 | 1.95 |
ENST00000284984.3
|
ADAMTS1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| chr20_+_58179582 | 1.89 |
ENST00000371015.1
ENST00000395639.4 |
PHACTR3
|
phosphatase and actin regulator 3 |
| chr11_-_107729887 | 1.88 |
ENST00000525815.1
|
SLC35F2
|
solute carrier family 35, member F2 |
| chr20_+_62327996 | 1.88 |
ENST00000369996.1
|
TNFRSF6B
|
tumor necrosis factor receptor superfamily, member 6b, decoy |
| chr6_-_27114577 | 1.85 |
ENST00000356950.1
ENST00000396891.4 |
HIST1H2BK
|
histone cluster 1, H2bk |
| chr12_+_130646999 | 1.82 |
ENST00000539839.1
ENST00000229030.4 |
FZD10
|
frizzled family receptor 10 |
| chr18_+_34124507 | 1.82 |
ENST00000591635.1
|
FHOD3
|
formin homology 2 domain containing 3 |
| chr17_-_39140549 | 1.82 |
ENST00000377755.4
|
KRT40
|
keratin 40 |
| chr11_-_128392085 | 1.80 |
ENST00000526145.2
ENST00000531611.1 ENST00000319397.6 ENST00000345075.4 ENST00000535549.1 |
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| chr7_+_80275953 | 1.80 |
ENST00000538969.1
ENST00000544133.1 ENST00000433696.2 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr7_+_40174565 | 1.78 |
ENST00000309930.5
ENST00000401647.2 ENST00000335693.4 ENST00000413931.1 ENST00000416370.1 ENST00000540834.1 |
C7orf10
|
succinylCoA:glutarate-CoA transferase |
| chr20_+_3776371 | 1.75 |
ENST00000245960.5
|
CDC25B
|
cell division cycle 25B |
| chr1_-_9129735 | 1.74 |
ENST00000377424.4
|
SLC2A5
|
solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| chr20_+_42984330 | 1.69 |
ENST00000316673.4
ENST00000609795.1 ENST00000457232.1 ENST00000609262.1 |
HNF4A
|
hepatocyte nuclear factor 4, alpha |
| chr3_+_57875738 | 1.68 |
ENST00000417128.1
ENST00000438794.1 |
SLMAP
|
sarcolemma associated protein |
| chr2_-_208031943 | 1.63 |
ENST00000421199.1
ENST00000457962.1 |
KLF7
|
Kruppel-like factor 7 (ubiquitous) |
| chr7_+_80275752 | 1.62 |
ENST00000419819.2
|
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr19_+_35634146 | 1.61 |
ENST00000586063.1
ENST00000270310.2 ENST00000588265.1 |
FXYD7
|
FXYD domain containing ion transport regulator 7 |
| chr13_-_103719196 | 1.60 |
ENST00000245312.3
|
SLC10A2
|
solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| chr12_-_30887948 | 1.59 |
ENST00000433722.2
|
CAPRIN2
|
caprin family member 2 |
| chr15_+_67418047 | 1.57 |
ENST00000540846.2
|
SMAD3
|
SMAD family member 3 |
| chr7_+_134576151 | 1.57 |
ENST00000393118.2
|
CALD1
|
caldesmon 1 |
| chr17_+_7211656 | 1.54 |
ENST00000416016.2
|
EIF5A
|
eukaryotic translation initiation factor 5A |
| chr8_+_52730143 | 1.53 |
ENST00000415643.1
|
AC090186.1
|
Uncharacterized protein |
| chr7_-_50860565 | 1.51 |
ENST00000403097.1
|
GRB10
|
growth factor receptor-bound protein 10 |
| chr11_+_63606373 | 1.50 |
ENST00000402010.2
ENST00000315032.8 ENST00000377809.4 ENST00000413835.2 ENST00000377810.3 |
MARK2
|
MAP/microtubule affinity-regulating kinase 2 |
| chr7_+_80275621 | 1.49 |
ENST00000426978.1
ENST00000432207.1 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr7_-_76255444 | 1.47 |
ENST00000454397.1
|
POMZP3
|
POM121 and ZP3 fusion |
| chr12_+_93096619 | 1.46 |
ENST00000397833.3
|
C12orf74
|
chromosome 12 open reading frame 74 |
| chr16_+_55600580 | 1.44 |
ENST00000457326.2
|
CAPNS2
|
calpain, small subunit 2 |
| chr8_-_125486755 | 1.42 |
ENST00000499418.2
ENST00000530778.1 |
RNF139-AS1
|
RNF139 antisense RNA 1 (head to head) |
| chr6_-_27775694 | 1.40 |
ENST00000377401.2
|
HIST1H2BL
|
histone cluster 1, H2bl |
| chr1_-_155880672 | 1.40 |
ENST00000609492.1
ENST00000368322.3 |
RIT1
|
Ras-like without CAAX 1 |
| chr18_+_61445007 | 1.38 |
ENST00000447428.1
ENST00000546027.1 |
SERPINB7
|
serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
| chr4_-_68749745 | 1.38 |
ENST00000283916.6
|
TMPRSS11D
|
transmembrane protease, serine 11D |
| chr21_-_31859755 | 1.38 |
ENST00000334055.3
|
KRTAP19-2
|
keratin associated protein 19-2 |
| chr2_+_210444748 | 1.38 |
ENST00000392194.1
|
MAP2
|
microtubule-associated protein 2 |
| chr11_+_69924639 | 1.37 |
ENST00000538023.1
ENST00000398543.2 |
ANO1
|
anoctamin 1, calcium activated chloride channel |
| chr19_+_1440838 | 1.34 |
ENST00000594262.1
|
AC027307.3
|
Uncharacterized protein |
| chr12_-_8814669 | 1.34 |
ENST00000535411.1
ENST00000540087.1 |
MFAP5
|
microfibrillar associated protein 5 |
| chr18_-_5396271 | 1.33 |
ENST00000579951.1
|
EPB41L3
|
erythrocyte membrane protein band 4.1-like 3 |
| chr12_+_93096759 | 1.32 |
ENST00000544406.2
|
C12orf74
|
chromosome 12 open reading frame 74 |
| chr1_-_237167718 | 1.32 |
ENST00000464121.2
|
MT1HL1
|
metallothionein 1H-like 1 |
| chr14_-_51027838 | 1.28 |
ENST00000555216.1
|
MAP4K5
|
mitogen-activated protein kinase kinase kinase kinase 5 |
| chr10_-_24770632 | 1.27 |
ENST00000596413.1
|
AL353583.1
|
AL353583.1 |
| chr3_+_57882024 | 1.27 |
ENST00000494088.1
|
SLMAP
|
sarcolemma associated protein |
| chr11_-_7961141 | 1.27 |
ENST00000360759.3
|
OR10A3
|
olfactory receptor, family 10, subfamily A, member 3 |
| chr4_+_48018781 | 1.26 |
ENST00000295461.5
|
NIPAL1
|
NIPA-like domain containing 1 |
| chr1_+_52682052 | 1.25 |
ENST00000371591.1
|
ZFYVE9
|
zinc finger, FYVE domain containing 9 |
| chr15_-_75017711 | 1.24 |
ENST00000567032.1
ENST00000564596.1 ENST00000566503.1 ENST00000395049.4 ENST00000395048.2 ENST00000379727.3 |
CYP1A1
|
cytochrome P450, family 1, subfamily A, polypeptide 1 |
| chr9_+_125133315 | 1.22 |
ENST00000223423.4
ENST00000362012.2 |
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chr17_-_39646116 | 1.22 |
ENST00000328119.6
|
KRT36
|
keratin 36 |
| chr20_+_16729003 | 1.21 |
ENST00000246081.2
|
OTOR
|
otoraplin |
| chr1_-_9129631 | 1.20 |
ENST00000377414.3
|
SLC2A5
|
solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| chr5_+_39105358 | 1.19 |
ENST00000593965.1
|
AC008964.1
|
AC008964.1 |
| chr2_+_33359687 | 1.18 |
ENST00000402934.1
ENST00000404525.1 ENST00000407925.1 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr7_+_1727755 | 1.15 |
ENST00000424383.2
|
ELFN1
|
extracellular leucine-rich repeat and fibronectin type III domain containing 1 |
| chr1_-_43919573 | 1.14 |
ENST00000372432.1
ENST00000372425.4 ENST00000583037.1 |
HYI
|
hydroxypyruvate isomerase (putative) |
| chr15_+_41549105 | 1.13 |
ENST00000560965.1
|
CHP1
|
calcineurin-like EF-hand protein 1 |
| chrX_+_99899180 | 1.13 |
ENST00000373004.3
|
SRPX2
|
sushi-repeat containing protein, X-linked 2 |
| chr15_-_55541227 | 1.13 |
ENST00000566877.1
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr2_+_33359646 | 1.11 |
ENST00000390003.4
ENST00000418533.2 |
LTBP1
|
latent transforming growth factor beta binding protein 1 |
| chr17_-_39507064 | 1.11 |
ENST00000007735.3
|
KRT33A
|
keratin 33A |
| chr1_-_43919346 | 1.09 |
ENST00000372430.3
ENST00000372433.1 ENST00000372434.1 ENST00000486909.1 |
HYI
|
hydroxypyruvate isomerase (putative) |
| chr2_-_238322800 | 1.06 |
ENST00000392004.3
ENST00000433762.1 ENST00000347401.3 ENST00000353578.4 ENST00000346358.4 ENST00000392003.2 |
COL6A3
|
collagen, type VI, alpha 3 |
| chr1_+_74701062 | 1.06 |
ENST00000326637.3
|
TNNI3K
|
TNNI3 interacting kinase |
| chr9_+_131084846 | 1.06 |
ENST00000608951.1
|
COQ4
|
coenzyme Q4 |
| chr11_-_5537920 | 1.05 |
ENST00000380184.1
|
UBQLNL
|
ubiquilin-like |
| chr19_+_48497962 | 1.05 |
ENST00000596043.1
ENST00000597519.1 |
ELSPBP1
|
epididymal sperm binding protein 1 |
| chr17_-_39637392 | 1.05 |
ENST00000246639.2
ENST00000393989.1 |
KRT35
|
keratin 35 |
| chr3_+_160394940 | 1.03 |
ENST00000320767.2
|
ARL14
|
ADP-ribosylation factor-like 14 |
| chr9_-_21305312 | 1.03 |
ENST00000259555.4
|
IFNA5
|
interferon, alpha 5 |
| chr16_-_80926457 | 1.02 |
ENST00000563626.1
ENST00000562231.1 |
RP11-314O13.1
|
RP11-314O13.1 |
| chr2_+_101591314 | 1.02 |
ENST00000450763.1
|
NPAS2
|
neuronal PAS domain protein 2 |
| chr1_-_9129598 | 1.01 |
ENST00000535586.1
|
SLC2A5
|
solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| chr2_-_165424973 | 1.00 |
ENST00000543549.1
|
GRB14
|
growth factor receptor-bound protein 14 |
| chr11_-_2158507 | 0.99 |
ENST00000381392.1
ENST00000381395.1 ENST00000418738.2 |
IGF2
|
insulin-like growth factor 2 (somatomedin A) |
| chr19_+_48497901 | 0.98 |
ENST00000339841.2
|
ELSPBP1
|
epididymal sperm binding protein 1 |
| chr12_-_18243119 | 0.98 |
ENST00000538724.1
ENST00000229002.2 |
RERGL
|
RERG/RAS-like |
| chr18_+_21032781 | 0.98 |
ENST00000339486.3
|
RIOK3
|
RIO kinase 3 |
| chr4_+_54966198 | 0.97 |
ENST00000326902.2
ENST00000503800.1 |
GSX2
|
GS homeobox 2 |
| chr22_-_50524298 | 0.97 |
ENST00000311597.5
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr9_+_75229616 | 0.97 |
ENST00000340019.3
|
TMC1
|
transmembrane channel-like 1 |
| chr6_-_111888474 | 0.96 |
ENST00000368735.1
|
TRAF3IP2
|
TRAF3 interacting protein 2 |
| chr17_-_53809473 | 0.95 |
ENST00000575734.1
|
TMEM100
|
transmembrane protein 100 |
| chr9_+_125132803 | 0.93 |
ENST00000540753.1
|
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chr1_+_192127578 | 0.92 |
ENST00000367460.3
|
RGS18
|
regulator of G-protein signaling 18 |
| chr7_-_92747269 | 0.92 |
ENST00000446617.1
ENST00000379958.2 |
SAMD9
|
sterile alpha motif domain containing 9 |
| chr17_-_39538550 | 0.92 |
ENST00000394001.1
|
KRT34
|
keratin 34 |
| chr7_-_36634181 | 0.90 |
ENST00000538464.1
|
AOAH
|
acyloxyacyl hydrolase (neutrophil) |
| chr17_+_61086917 | 0.90 |
ENST00000424789.2
ENST00000389520.4 |
TANC2
|
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| chr12_-_91576561 | 0.89 |
ENST00000547568.2
ENST00000552962.1 |
DCN
|
decorin |
| chr12_-_52715179 | 0.89 |
ENST00000293670.3
|
KRT83
|
keratin 83 |
| chr17_+_17082842 | 0.88 |
ENST00000579361.1
|
MPRIP
|
myosin phosphatase Rho interacting protein |
| chr7_+_134430212 | 0.88 |
ENST00000436461.2
|
CALD1
|
caldesmon 1 |
| chr5_+_135496675 | 0.88 |
ENST00000507637.1
|
SMAD5
|
SMAD family member 5 |
| chr15_-_89764929 | 0.88 |
ENST00000268125.5
|
RLBP1
|
retinaldehyde binding protein 1 |
| chr4_+_71248795 | 0.87 |
ENST00000304915.3
|
SMR3B
|
submaxillary gland androgen regulated protein 3B |
| chr8_-_60031762 | 0.87 |
ENST00000361421.1
|
TOX
|
thymocyte selection-associated high mobility group box |
| chr14_-_107170409 | 0.85 |
ENST00000390633.2
|
IGHV1-69
|
immunoglobulin heavy variable 1-69 |
| chr2_-_238323007 | 0.85 |
ENST00000295550.4
|
COL6A3
|
collagen, type VI, alpha 3 |
| chr11_+_64001962 | 0.84 |
ENST00000309422.2
|
VEGFB
|
vascular endothelial growth factor B |
| chr6_+_130339710 | 0.83 |
ENST00000526087.1
ENST00000533560.1 ENST00000361794.2 |
L3MBTL3
|
l(3)mbt-like 3 (Drosophila) |
| chr14_+_73706308 | 0.83 |
ENST00000554301.1
ENST00000555445.1 |
PAPLN
|
papilin, proteoglycan-like sulfated glycoprotein |
| chr11_-_19082216 | 0.83 |
ENST00000329773.2
|
MRGPRX2
|
MAS-related GPR, member X2 |
| chr6_+_53948328 | 0.82 |
ENST00000370876.2
|
MLIP
|
muscular LMNA-interacting protein |
| chr6_+_42584847 | 0.80 |
ENST00000372883.3
|
UBR2
|
ubiquitin protein ligase E3 component n-recognin 2 |
| chr2_+_183580954 | 0.80 |
ENST00000264065.7
|
DNAJC10
|
DnaJ (Hsp40) homolog, subfamily C, member 10 |
| chr6_-_100442077 | 0.80 |
ENST00000281806.2
ENST00000369212.2 |
MCHR2
|
melanin-concentrating hormone receptor 2 |
| chr12_+_71833756 | 0.79 |
ENST00000536515.1
ENST00000540815.2 |
LGR5
|
leucine-rich repeat containing G protein-coupled receptor 5 |
| chr6_-_108145499 | 0.76 |
ENST00000369020.3
ENST00000369022.2 |
SCML4
|
sex comb on midleg-like 4 (Drosophila) |
| chr12_-_18243075 | 0.76 |
ENST00000536890.1
|
RERGL
|
RERG/RAS-like |
| chr13_+_109248500 | 0.76 |
ENST00000356711.2
|
MYO16
|
myosin XVI |
| chr19_-_10420459 | 0.75 |
ENST00000403352.1
ENST00000403903.3 |
ZGLP1
|
zinc finger, GATA-like protein 1 |
| chr21_+_17792672 | 0.75 |
ENST00000602620.1
|
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr12_-_91576750 | 0.75 |
ENST00000228329.5
ENST00000303320.3 ENST00000052754.5 |
DCN
|
decorin |
| chr7_-_27205136 | 0.75 |
ENST00000396345.1
ENST00000343483.6 |
HOXA9
|
homeobox A9 |
| chr5_+_95997769 | 0.74 |
ENST00000338252.3
ENST00000508830.1 |
CAST
|
calpastatin |
| chrX_+_65384052 | 0.74 |
ENST00000336279.5
ENST00000458621.1 |
HEPH
|
hephaestin |
| chr3_-_51813009 | 0.73 |
ENST00000398780.3
|
IQCF6
|
IQ motif containing F6 |
| chr12_-_117799446 | 0.73 |
ENST00000317775.6
ENST00000344089.3 |
NOS1
|
nitric oxide synthase 1 (neuronal) |
| chr3_-_37216055 | 0.72 |
ENST00000336686.4
|
LRRFIP2
|
leucine rich repeat (in FLII) interacting protein 2 |
| chr10_+_90354503 | 0.72 |
ENST00000531458.1
|
LIPJ
|
lipase, family member J |
| chr8_+_128426535 | 0.71 |
ENST00000465342.2
|
POU5F1B
|
POU class 5 homeobox 1B |
| chr19_+_10397648 | 0.71 |
ENST00000340992.4
ENST00000393717.2 |
ICAM4
|
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| chr13_-_46626847 | 0.71 |
ENST00000242848.4
ENST00000282007.3 |
ZC3H13
|
zinc finger CCCH-type containing 13 |
| chr2_+_105050794 | 0.71 |
ENST00000429464.1
ENST00000414442.1 ENST00000447380.1 |
AC013402.2
|
long intergenic non-protein coding RNA 1102 |
| chr20_-_50722183 | 0.71 |
ENST00000371523.4
|
ZFP64
|
ZFP64 zinc finger protein |
| chr1_+_192544857 | 0.71 |
ENST00000367459.3
ENST00000469578.2 |
RGS1
|
regulator of G-protein signaling 1 |
| chr6_-_10415470 | 0.70 |
ENST00000379604.2
ENST00000379613.3 |
TFAP2A
|
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| chr7_-_142139783 | 0.70 |
ENST00000390374.3
|
TRBV7-6
|
T cell receptor beta variable 7-6 |
| chr16_+_2285817 | 0.70 |
ENST00000564065.1
|
DNASE1L2
|
deoxyribonuclease I-like 2 |
| chr8_+_77593448 | 0.70 |
ENST00000521891.2
|
ZFHX4
|
zinc finger homeobox 4 |
| chr1_-_161207875 | 0.69 |
ENST00000512372.1
ENST00000437437.2 ENST00000442691.2 ENST00000412844.2 ENST00000428574.2 ENST00000505005.1 ENST00000508740.1 ENST00000508387.1 ENST00000504010.1 ENST00000511676.1 ENST00000502985.1 ENST00000367981.3 ENST00000515621.1 ENST00000511944.1 ENST00000511748.1 ENST00000367984.4 ENST00000367985.3 |
NR1I3
|
nuclear receptor subfamily 1, group I, member 3 |
| chr9_+_82187487 | 0.69 |
ENST00000435650.1
ENST00000414465.1 ENST00000376537.4 ENST00000376534.4 |
TLE4
|
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) |
| chr10_-_29923893 | 0.69 |
ENST00000355867.4
|
SVIL
|
supervillin |
| chr3_+_101546827 | 0.68 |
ENST00000461724.1
ENST00000483180.1 ENST00000394054.2 |
NFKBIZ
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
| chr7_+_141490017 | 0.68 |
ENST00000247883.4
|
TAS2R5
|
taste receptor, type 2, member 5 |
| chr12_-_95044309 | 0.67 |
ENST00000261226.4
|
TMCC3
|
transmembrane and coiled-coil domain family 3 |
| chr8_+_31496809 | 0.67 |
ENST00000518104.1
ENST00000519301.1 |
NRG1
|
neuregulin 1 |
| chr1_-_242162375 | 0.67 |
ENST00000357246.3
|
MAP1LC3C
|
microtubule-associated protein 1 light chain 3 gamma |
| chr16_+_86612112 | 0.66 |
ENST00000320241.3
|
FOXL1
|
forkhead box L1 |
| chrX_+_65382433 | 0.66 |
ENST00000374727.3
|
HEPH
|
hephaestin |
| chr14_+_22356029 | 0.66 |
ENST00000390437.2
|
TRAV12-2
|
T cell receptor alpha variable 12-2 |
| chr9_+_36572851 | 0.65 |
ENST00000298048.2
ENST00000538311.1 ENST00000536987.1 ENST00000545008.1 ENST00000536860.1 ENST00000536329.1 ENST00000541717.1 ENST00000543751.1 |
MELK
|
maternal embryonic leucine zipper kinase |
| chr4_-_52883786 | 0.64 |
ENST00000343457.3
|
LRRC66
|
leucine rich repeat containing 66 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC10_HOXD13
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.5 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
| 1.9 | 5.6 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 1.3 | 9.4 | GO:0097338 | response to clozapine(GO:0097338) |
| 1.2 | 3.6 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 1.0 | 2.9 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.7 | 4.9 | GO:2000334 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.7 | 2.1 | GO:0060585 | regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
| 0.6 | 8.1 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
| 0.6 | 2.8 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.5 | 3.8 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.5 | 8.0 | GO:0035878 | nail development(GO:0035878) |
| 0.5 | 3.4 | GO:0032445 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.4 | 3.1 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.4 | 1.2 | GO:0018894 | dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449) |
| 0.4 | 2.0 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.4 | 2.7 | GO:0040038 | polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649) |
| 0.3 | 1.4 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.3 | 1.6 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.3 | 2.1 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.2 | 1.0 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.2 | 1.5 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.2 | 0.7 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.2 | 1.0 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
| 0.2 | 2.3 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 1.8 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.2 | 1.8 | GO:0030578 | PML body organization(GO:0030578) |
| 0.2 | 3.3 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.2 | 0.7 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.2 | 1.7 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.2 | 0.6 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
| 0.2 | 0.4 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 0.2 | 1.5 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 0.6 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.2 | 1.1 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.2 | 0.7 | GO:0003404 | optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409) |
| 0.2 | 0.7 | GO:0003335 | corneocyte development(GO:0003335) |
| 0.2 | 0.3 | GO:0014916 | regulation of lung blood pressure(GO:0014916) |
| 0.2 | 1.3 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 22.9 | GO:0070268 | cornification(GO:0070268) |
| 0.2 | 1.0 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.2 | 0.5 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 0.2 | 0.8 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.2 | 2.7 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.2 | 1.8 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.2 | 7.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.2 | 1.4 | GO:0015705 | iodide transport(GO:0015705) |
| 0.1 | 0.4 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 0.1 | 0.7 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.1 | 0.9 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.1 | 0.4 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.1 | 1.1 | GO:0070885 | positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
| 0.1 | 0.6 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.1 | 0.8 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.1 | 1.3 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.1 | 0.5 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
| 0.1 | 0.7 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
| 0.1 | 0.4 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.1 | 0.6 | GO:0001757 | somite specification(GO:0001757) |
| 0.1 | 1.0 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.1 | 0.9 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.1 | 0.5 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.1 | 0.1 | GO:0008078 | mesoderm migration involved in gastrulation(GO:0007509) mesodermal cell migration(GO:0008078) |
| 0.1 | 0.5 | GO:0036292 | DNA rewinding(GO:0036292) |
| 0.1 | 1.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 2.4 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.1 | 0.9 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.1 | 4.3 | GO:0032402 | melanosome transport(GO:0032402) |
| 0.1 | 1.5 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.1 | 3.1 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.1 | 1.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 1.9 | GO:0060347 | heart trabecula formation(GO:0060347) |
| 0.1 | 0.7 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.1 | 2.1 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.1 | 0.3 | GO:1900158 | positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.1 | 0.5 | GO:0030047 | actin modification(GO:0030047) |
| 0.1 | 1.3 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 1.9 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.1 | 1.3 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 1.3 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.1 | 1.0 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.1 | 0.3 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.1 | 0.3 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.1 | 0.3 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.1 | 0.3 | GO:0097045 | phosphatidylserine exposure on blood platelet(GO:0097045) |
| 0.1 | 0.6 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.1 | 0.2 | GO:0090293 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 0.1 | 0.4 | GO:0032571 | response to vitamin K(GO:0032571) bone regeneration(GO:1990523) |
| 0.1 | 0.2 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) |
| 0.1 | 0.2 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.1 | 0.9 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 3.8 | GO:1902808 | positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.1 | 0.5 | GO:0003383 | apical constriction(GO:0003383) |
| 0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.1 | 0.8 | GO:0019720 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.1 | 0.2 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.1 | 0.6 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.1 | 2.6 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.1 | 0.4 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.1 | 0.8 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 1.0 | GO:0051775 | response to redox state(GO:0051775) |
| 0.1 | 2.0 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.1 | 0.3 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.1 | 0.3 | GO:0090107 | regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.1 | 0.3 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.1 | 0.9 | GO:0086069 | bundle of His cell to Purkinje myocyte communication(GO:0086069) |
| 0.1 | 0.3 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 0.3 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.1 | 1.0 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 0.1 | 0.3 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 0.1 | 0.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.1 | 1.0 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.1 | 0.6 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.1 | 0.4 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) |
| 0.1 | 0.1 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 0.1 | 0.3 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
| 0.1 | 0.4 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.1 | 0.5 | GO:0060750 | epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) |
| 0.1 | 1.4 | GO:1901663 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.1 | 0.2 | GO:1903970 | negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) |
| 0.1 | 0.2 | GO:0048340 | paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) |
| 0.1 | 0.4 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.1 | 1.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 0.5 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.1 | 0.2 | GO:0002590 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) |
| 0.1 | 1.0 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.1 | 0.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 1.6 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.1 | 0.3 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.1 | 0.2 | GO:0035992 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.0 | 0.2 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.0 | 0.2 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.0 | 0.1 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.0 | 0.6 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.0 | 0.3 | GO:0060992 | guanine metabolic process(GO:0046098) response to fungicide(GO:0060992) |
| 0.0 | 0.1 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 0.0 | 0.1 | GO:0003186 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) tricuspid valve morphogenesis(GO:0003186) |
| 0.0 | 0.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 0.1 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.0 | 0.3 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 0.0 | 0.3 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.0 | 0.1 | GO:0038033 | positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) |
| 0.0 | 0.2 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.0 | 0.5 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 0.1 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
| 0.0 | 0.5 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 1.7 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.0 | 0.2 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.0 | 0.4 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.0 | 0.4 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.2 | GO:0070375 | ERK5 cascade(GO:0070375) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.0 | 0.2 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.0 | 0.5 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 0.1 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 0.0 | 0.8 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
| 0.0 | 0.3 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.0 | 0.1 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.0 | 0.6 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.0 | 0.1 | GO:0048867 | ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867) |
| 0.0 | 0.1 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.9 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.0 | 0.1 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.0 | 0.7 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.2 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) |
| 0.0 | 0.3 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.0 | 0.2 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.0 | 0.5 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.0 | 0.2 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.0 | 0.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.1 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.0 | 0.9 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.1 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.0 | 0.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.3 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
| 0.0 | 2.9 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.2 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.0 | 1.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.5 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168) |
| 0.0 | 1.3 | GO:0097435 | fibril organization(GO:0097435) |
| 0.0 | 0.4 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.0 | 1.4 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 1.0 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.0 | 0.3 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.0 | 0.7 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 0.8 | GO:0031061 | negative regulation of histone methylation(GO:0031061) |
| 0.0 | 0.4 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.0 | 2.6 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.7 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.0 | 0.2 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
| 0.0 | 0.1 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.0 | 0.4 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.0 | 0.5 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
| 0.0 | 1.5 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 0.6 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 1.0 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
| 0.0 | 0.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.2 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.0 | 0.1 | GO:0045726 | positive regulation of integrin biosynthetic process(GO:0045726) |
| 0.0 | 0.2 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.0 | 2.2 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.1 | GO:0035905 | N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.0 | 0.1 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 0.2 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.0 | 0.3 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 0.6 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 0.8 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.6 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.0 | 2.3 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.6 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 0.2 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.0 | 0.3 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.0 | 2.9 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 0.1 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 0.0 | 0.1 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.0 | 0.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.6 | GO:0002931 | response to ischemia(GO:0002931) |
| 0.0 | 0.2 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.0 | 0.3 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.5 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 9.2 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 0.1 | GO:0070778 | L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712) |
| 0.0 | 0.8 | GO:0048599 | oocyte development(GO:0048599) |
| 0.0 | 0.1 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.0 | 0.1 | GO:0018211 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.2 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.4 | GO:1905145 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.0 | 0.2 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.0 | 0.2 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 1.1 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.0 | 0.8 | GO:0032873 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 0.0 | 0.5 | GO:0003091 | renal water homeostasis(GO:0003091) |
| 0.0 | 1.3 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 2.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 1.8 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 1.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.5 | GO:0070423 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) |
| 0.0 | 0.3 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.0 | 0.2 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
| 0.0 | 0.1 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.0 | 0.3 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 0.3 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.1 | GO:0042355 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 0.3 | GO:0015992 | proton transport(GO:0015992) |
| 0.0 | 0.1 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.0 | 0.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.8 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 1.1 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.0 | 0.3 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392) |
| 0.0 | 4.0 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.0 | 0.3 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.0 | 0.2 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.0 | 2.1 | GO:0009408 | response to heat(GO:0009408) |
| 0.0 | 0.8 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.0 | 0.2 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.5 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.4 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.0 | 0.3 | GO:0006839 | mitochondrial transport(GO:0006839) |
| 0.0 | 0.6 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 0.1 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 0.0 | 0.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.8 | GO:0021549 | cerebellum development(GO:0021549) |
| 0.0 | 0.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.1 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
| 0.0 | 1.4 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.0 | 0.2 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.6 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 1.2 | 3.6 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 1.0 | 14.4 | GO:0030478 | actin cap(GO:0030478) |
| 0.9 | 2.6 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.8 | 3.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.7 | 9.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.5 | 2.1 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.4 | 9.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.4 | 5.2 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.4 | 2.8 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.3 | 1.2 | GO:0031417 | NatC complex(GO:0031417) |
| 0.3 | 2.1 | GO:0070695 | FHF complex(GO:0070695) |
| 0.3 | 7.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.3 | 3.4 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.3 | 0.8 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.2 | 0.7 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.2 | 1.5 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.2 | 0.6 | GO:0000806 | Y chromosome(GO:0000806) |
| 0.2 | 1.6 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.2 | 4.3 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.2 | 3.0 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 1.2 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.2 | 0.7 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 3.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.7 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.1 | 1.3 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 24.3 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 4.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.8 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.1 | 1.5 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 4.5 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 5.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.4 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 0.4 | GO:0005600 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.1 | 1.0 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 1.1 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.1 | 0.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.1 | 1.0 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.1 | 0.9 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 0.6 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 3.4 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 1.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 3.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 4.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.3 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 0.5 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 0.1 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.0 | 0.5 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.5 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.5 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.0 | 0.2 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.0 | 0.1 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 0.6 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.3 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.9 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.7 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.3 | GO:0031410 | cytoplasmic vesicle(GO:0031410) |
| 0.0 | 4.2 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 2.3 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.1 | GO:0097679 | other organism cytoplasm(GO:0097679) |
| 0.0 | 0.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.8 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 0.4 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 0.1 | GO:0044214 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.0 | 0.2 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 0.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.6 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.2 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.4 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.9 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.2 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 1.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.5 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.0 | 0.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.0 | 0.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.2 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 1.3 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 2.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 0.2 | GO:0043296 | bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160) |
| 0.0 | 0.1 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 2.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 3.0 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 1.1 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.3 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 1.0 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 0.2 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.5 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.0 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.0 | 2.3 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.9 | 13.2 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.8 | 4.9 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.8 | 2.4 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.5 | 2.2 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.5 | 1.1 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.5 | 9.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.5 | 3.4 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.5 | 8.7 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.5 | 8.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.5 | 2.3 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.4 | 13.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.4 | 2.1 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.4 | 2.0 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.4 | 2.2 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.3 | 1.6 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.3 | 1.6 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.3 | 3.1 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.3 | 0.9 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 0.3 | 1.2 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.3 | 1.4 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.2 | 1.2 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 0.2 | 3.0 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.2 | 1.3 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.2 | 2.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 0.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 2.2 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.2 | 2.8 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.2 | 0.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.2 | 0.7 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.2 | 3.6 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.2 | 9.5 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 1.5 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.1 | 0.6 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 0.8 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 0.4 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.1 | 0.9 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 0.1 | 1.2 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 3.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.4 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 4.9 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 0.8 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 2.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.4 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.1 | 0.7 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 1.8 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 0.7 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.1 | 0.4 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.1 | 0.5 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.1 | 0.3 | GO:0061752 | telomeric repeat-containing RNA binding(GO:0061752) |
| 0.1 | 0.9 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 0.3 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.1 | 3.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 0.3 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.1 | 0.9 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.1 | 0.2 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 0.1 | 1.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 0.5 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.1 | 1.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 8.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.3 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.1 | 1.0 | GO:0089720 | caspase binding(GO:0089720) |
| 0.1 | 1.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.2 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.1 | 0.2 | GO:0001181 | transcription factor activity, core RNA polymerase I binding(GO:0001181) |
| 0.1 | 0.2 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.1 | 0.3 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.1 | 0.6 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 0.5 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 1.0 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.1 | 0.5 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.1 | 0.5 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 1.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 1.3 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 0.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.1 | 0.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.1 | 0.4 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.1 | 0.4 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 4.2 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 1.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 0.2 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.1 | 0.8 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.1 | 0.3 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.1 | 0.2 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.1 | 1.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 2.5 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 0.4 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 0.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.1 | 0.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.0 | 1.9 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.1 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.1 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.0 | 0.5 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.0 | 5.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.6 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.0 | 0.3 | GO:0016615 | malate dehydrogenase activity(GO:0016615) |
| 0.0 | 1.6 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 3.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 1.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 1.1 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 2.2 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.3 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.0 | 0.5 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.0 | 0.3 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.0 | 0.8 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.0 | 0.5 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.1 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.0 | 0.3 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.0 | 0.1 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.0 | 0.1 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.0 | 0.2 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.0 | 0.9 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.0 | 0.4 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 1.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.0 | 0.6 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 0.1 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.0 | 0.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 1.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 5.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.2 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.0 | 0.1 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.0 | 0.3 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.6 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.6 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 0.3 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 0.0 | 0.2 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.0 | 0.2 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.0 | 3.8 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.2 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.0 | 1.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.4 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.2 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.5 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.3 | GO:0016918 | retinal binding(GO:0016918) |
| 0.0 | 0.3 | GO:0015085 | calcium-transporting ATPase activity(GO:0005388) calcium ion transmembrane transporter activity(GO:0015085) |
| 0.0 | 6.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 2.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.3 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.1 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.7 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 4.5 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 2.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.4 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.4 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.0 | 0.1 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.0 | 0.1 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 0.0 | 0.3 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 2.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.9 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.2 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.1 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.2 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.0 | 0.1 | GO:0001595 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.0 | 0.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.4 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.1 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.0 | 0.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.3 | GO:0042166 | acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166) |
| 0.0 | 0.2 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.4 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 0.4 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 0.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 18.6 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.3 | 8.1 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.2 | 9.4 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.2 | 9.5 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 1.8 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 4.7 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.1 | 2.8 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 2.6 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.1 | 5.4 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 4.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 5.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 4.8 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 0.8 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 1.8 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 15.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 3.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.7 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 3.1 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 0.9 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 2.7 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 1.0 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.7 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 0.5 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.8 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 0.3 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.3 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.2 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.9 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 1.1 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 1.0 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.3 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.1 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.7 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.3 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 0.3 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.8 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.4 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.6 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.3 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 0.7 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.1 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 0.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 1.3 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.2 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.6 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.2 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.7 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.6 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.7 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.1 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.4 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.6 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.1 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 8.1 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.4 | 1.6 | REACTOME BILE ACID AND BILE SALT METABOLISM | Genes involved in Bile acid and bile salt metabolism |
| 0.3 | 9.4 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.3 | 2.8 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.3 | 9.4 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.2 | 15.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 8.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.2 | 2.7 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.2 | 3.4 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 1.9 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 9.5 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 3.3 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 3.4 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 1.5 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 3.0 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 4.0 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 1.4 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.1 | 1.8 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 1.2 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 2.4 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 0.5 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 1.8 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.1 | 2.2 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 6.9 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 2.1 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.8 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 1.3 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 1.0 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.1 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 0.0 | 0.7 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.0 | 0.6 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 0.3 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 0.9 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.2 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.0 | 0.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.7 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.2 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 0.1 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.0 | 0.5 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.1 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.0 | 1.2 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.6 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.4 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.4 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.3 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.5 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.6 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.6 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 1.2 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.7 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 2.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.3 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.2 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 0.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 1.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.4 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 0.4 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 3.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.1 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.7 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 1.3 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.3 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 1.0 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |