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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXC11

Z-value: 0.51

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Transcription factors associated with HOXC11

Gene Symbol Gene ID Gene Info
HOXC11
ENSG00000123388.4 homeobox C11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC11hg19_v2_chr12_+_54366894_54366922-0.319.2e-02Click!

Activity profile of HOXC11 motif

Sorted Z-values of HOXC11 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_148521381 1.78 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr9_-_124989804 1.24 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr9_-_124976185 1.24 ENST00000464484.2
LHX6
LIM homeobox 6
chr9_-_124976154 1.23 ENST00000482062.1
LHX6
LIM homeobox 6
chr14_-_57272366 1.08 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr20_+_58179582 0.71 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr8_+_26435359 0.68 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr9_-_124990680 0.66 ENST00000541397.2
ENST00000560485.1
LHX6
LIM homeobox 6
chr2_+_228678550 0.60 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr7_-_93519471 0.59 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr4_+_169013666 0.57 ENST00000359299.3
ANXA10
annexin A10
chr1_-_204135450 0.55 ENST00000272190.8
ENST00000367195.2
REN
renin
chr1_+_209878182 0.55 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_+_75229616 0.55 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr13_+_109248500 0.53 ENST00000356711.2
MYO16
myosin XVI
chr15_+_67418047 0.51 ENST00000540846.2
SMAD3
SMAD family member 3
chr6_+_12290586 0.49 ENST00000379375.5
EDN1
endothelin 1
chr1_+_209859510 0.49 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr7_-_41742697 0.48 ENST00000242208.4
INHBA
inhibin, beta A
chr3_-_37216055 0.48 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr14_-_25479811 0.47 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr6_+_31683117 0.42 ENST00000375825.3
ENST00000375824.1
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr10_+_17271266 0.38 ENST00000224237.5
VIM
vimentin
chr4_+_144354644 0.34 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr12_-_52779433 0.34 ENST00000257951.3
KRT84
keratin 84
chr19_-_19626351 0.33 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr12_-_95510743 0.33 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr2_-_190044480 0.31 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr14_+_73706308 0.31 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr17_-_41739283 0.29 ENST00000393661.2
ENST00000318579.4
MEOX1
mesenchyme homeobox 1
chr7_+_134464414 0.29 ENST00000361901.2
CALD1
caldesmon 1
chr7_+_134464376 0.28 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chrX_-_107682702 0.28 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr1_-_237167718 0.28 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr7_+_35756092 0.27 ENST00000458087.3
AC018647.3
AC018647.3
chr19_+_1440838 0.27 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr7_-_81399411 0.27 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_94147385 0.27 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr3_-_51813009 0.26 ENST00000398780.3
IQCF6
IQ motif containing F6
chr14_-_57277163 0.25 ENST00000555006.1
OTX2
orthodenticle homeobox 2
chr1_-_9129598 0.25 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr10_-_24770632 0.25 ENST00000596413.1
AL353583.1
AL353583.1
chr1_-_9129895 0.24 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr2_+_27440229 0.24 ENST00000264705.4
ENST00000403525.1
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr8_+_42873548 0.24 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr2_+_158114051 0.24 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr6_+_88054530 0.23 ENST00000388923.4
C6orf163
chromosome 6 open reading frame 163
chr21_-_31869451 0.22 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr16_-_2314222 0.21 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr2_+_210444142 0.21 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr12_-_28124903 0.21 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr11_+_64001962 0.21 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr19_-_19626838 0.20 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr1_+_12524965 0.20 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr8_-_21669826 0.18 ENST00000517328.1
GFRA2
GDNF family receptor alpha 2
chrX_+_99899180 0.18 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr9_+_82188077 0.18 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_-_20053741 0.17 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chrX_+_65382433 0.17 ENST00000374727.3
HEPH
hephaestin
chr8_-_18666360 0.17 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr15_+_69854027 0.16 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr1_+_26485511 0.16 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr14_-_72458326 0.16 ENST00000542853.1
AC005477.1
AC005477.1
chr19_-_36233332 0.15 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr1_-_9129735 0.15 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_-_123201337 0.15 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_+_130646999 0.15 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr2_-_136678123 0.15 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr18_-_12656715 0.15 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr8_+_26150628 0.15 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chrX_+_65384052 0.14 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr18_+_61223393 0.14 ENST00000269491.1
ENST00000382768.1
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr11_+_63606373 0.14 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr1_+_46152886 0.14 ENST00000372025.4
TMEM69
transmembrane protein 69
chr17_-_46690839 0.14 ENST00000498634.2
HOXB8
homeobox B8
chr20_+_42984330 0.14 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr1_+_66999268 0.14 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr22_-_30642782 0.13 ENST00000249075.3
LIF
leukemia inhibitory factor
chr11_+_34663913 0.13 ENST00000532302.1
EHF
ets homologous factor
chr3_+_15045419 0.13 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr15_+_49715293 0.13 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr19_-_45927622 0.13 ENST00000300853.3
ENST00000589165.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chrX_+_65384182 0.12 ENST00000441993.2
ENST00000419594.1
HEPH
hephaestin
chr11_-_102576537 0.12 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr6_-_41703952 0.12 ENST00000358871.2
ENST00000403298.4
TFEB
transcription factor EB
chr14_-_57277178 0.12 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr7_+_22766766 0.12 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr12_-_18243075 0.12 ENST00000536890.1
RERGL
RERG/RAS-like
chr7_-_81399355 0.11 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_12677714 0.11 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_+_52682052 0.11 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr1_-_242162375 0.11 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr3_+_89156674 0.11 ENST00000336596.2
EPHA3
EPH receptor A3
chr6_-_137815524 0.11 ENST00000367734.2
OLIG3
oligodendrocyte transcription factor 3
chr9_+_82187630 0.10 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_+_82187487 0.10 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_+_1800179 0.10 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr1_+_110993795 0.10 ENST00000271331.3
PROK1
prokineticin 1
chr7_-_27205136 0.10 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr17_-_79876010 0.09 ENST00000328666.6
SIRT7
sirtuin 7
chr1_-_9129631 0.09 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_+_70219052 0.09 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr11_-_132813566 0.09 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr20_+_4702548 0.08 ENST00000305817.2
PRND
prion protein 2 (dublet)
chr18_-_48351743 0.08 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO
maestro
chr2_+_176987088 0.08 ENST00000249499.6
HOXD9
homeobox D9
chr18_+_29769978 0.08 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr9_+_95736758 0.08 ENST00000337352.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr16_-_18466642 0.07 ENST00000541810.1
ENST00000531453.2
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr1_-_152131703 0.07 ENST00000316073.3
RPTN
repetin
chr12_-_18243119 0.07 ENST00000538724.1
ENST00000229002.2
RERGL
RERG/RAS-like
chr16_+_16429787 0.07 ENST00000331436.4
ENST00000541593.1
AC138969.4
Protein PKD1P1
chr6_+_15246501 0.07 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chrX_+_65382381 0.07 ENST00000519389.1
HEPH
hephaestin
chr2_-_207023918 0.07 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr22_+_41697520 0.07 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr2_-_50574856 0.07 ENST00000342183.5
NRXN1
neurexin 1
chr16_+_16472912 0.07 ENST00000530217.2
NPIPA7
nuclear pore complex interacting protein family, member A7
chr1_-_200379180 0.06 ENST00000294740.3
ZNF281
zinc finger protein 281
chr1_-_200379129 0.06 ENST00000367353.1
ZNF281
zinc finger protein 281
chr7_-_27169801 0.06 ENST00000511914.1
HOXA4
homeobox A4
chr12_-_24102576 0.05 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
SOX5
SRY (sex determining region Y)-box 5
chr1_-_113160826 0.05 ENST00000538187.1
ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr14_-_101295407 0.05 ENST00000596284.1
AL117190.2
AL117190.2
chr6_+_132873832 0.05 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr1_+_229440129 0.05 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr11_-_5537920 0.05 ENST00000380184.1
UBQLNL
ubiquilin-like
chr10_+_115614370 0.05 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr6_-_64029879 0.05 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr8_+_104831472 0.05 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr2_+_208423891 0.05 ENST00000448277.1
ENST00000457101.1
CREB1
cAMP responsive element binding protein 1
chr3_+_16306837 0.04 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr15_+_36887069 0.04 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr7_-_122840015 0.04 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr8_-_57123815 0.04 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr3_-_71294304 0.04 ENST00000498215.1
FOXP1
forkhead box P1
chr11_+_34664014 0.04 ENST00000527935.1
EHF
ets homologous factor
chr7_-_81399438 0.04 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr18_+_63417864 0.04 ENST00000536984.2
CDH7
cadherin 7, type 2
chr16_-_21431078 0.04 ENST00000458643.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr18_-_52989217 0.03 ENST00000570287.2
TCF4
transcription factor 4
chr14_-_51027838 0.03 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr16_+_15031300 0.03 ENST00000328085.6
NPIPA1
nuclear pore complex interacting protein family, member A1
chr18_+_3252206 0.03 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr18_+_3252265 0.03 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_109204909 0.03 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_-_88119580 0.03 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr20_-_56285595 0.03 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr2_-_40739501 0.03 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_+_148545586 0.03 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr7_-_151217166 0.03 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr13_-_74708372 0.02 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr2_-_176046391 0.02 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr4_-_163085107 0.02 ENST00000379164.4
FSTL5
follistatin-like 5
chr10_+_47894023 0.02 ENST00000358474.5
FAM21B
family with sequence similarity 21, member B
chr1_+_62439037 0.02 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr9_+_105757590 0.02 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr7_-_108209897 0.02 ENST00000313516.5
THAP5
THAP domain containing 5
chr12_-_54071181 0.02 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chrX_+_105192423 0.02 ENST00000540278.1
NRK
Nik related kinase
chr2_-_166930131 0.02 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr19_-_39924349 0.02 ENST00000602153.1
RPS16
ribosomal protein S16
chr8_+_134203273 0.01 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr5_+_145718587 0.01 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr5_-_82969405 0.00 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr3_+_63428982 0.00 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr3_-_45838011 0.00 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr3_-_79816965 0.00 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr12_-_71148413 0.00 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 0.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 0.5 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.7 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0 1.0 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 1.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.7 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins