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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXC12_HOXD12

Z-value: 1.43

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
HOXC12
ENSG00000123407.3 homeobox C12
HOXD12
ENSG00000170178.5 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD12hg19_v2_chr2_+_176964458_176964540-0.422.2e-02Click!
HOXC12hg19_v2_chr12_+_54348618_543486930.029.2e-01Click!

Activity profile of HOXC12_HOXD12 motif

Sorted Z-values of HOXC12_HOXD12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrY_+_2709527 24.01 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chrY_+_2709906 9.47 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr19_-_55677999 6.02 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3
dynein, axonemal, assembly factor 3
chr11_-_102668879 5.33 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr7_+_6797288 4.67 ENST00000433859.2
ENST00000359718.3
RSPH10B2
radial spoke head 10 homolog B2 (Chlamydomonas)
chr3_-_19975665 4.46 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr7_-_6006768 4.46 ENST00000441023.2
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr19_-_55677920 3.99 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr17_+_11501748 3.36 ENST00000262442.4
ENST00000579828.1
DNAH9
dynein, axonemal, heavy chain 9
chr1_-_47407097 2.95 ENST00000457840.2
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr3_+_63638339 2.80 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr1_+_171060018 2.63 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
FMO3
flavin containing monooxygenase 3
chr12_-_71551652 2.51 ENST00000546561.1
TSPAN8
tetraspanin 8
chr9_-_124976185 2.49 ENST00000464484.2
LHX6
LIM homeobox 6
chr8_+_101170563 2.45 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chr9_-_124976154 2.41 ENST00000482062.1
LHX6
LIM homeobox 6
chr8_-_33370607 2.30 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr3_-_172241250 2.21 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr7_+_152456904 2.14 ENST00000537264.1
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr11_-_107328527 1.96 ENST00000282251.5
ENST00000433523.1
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr13_-_24895566 1.92 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr4_-_16085340 1.81 ENST00000508167.1
PROM1
prominin 1
chr6_-_49681235 1.80 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr5_+_159656437 1.76 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr15_+_71185148 1.73 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr15_+_71184931 1.68 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr4_-_16085314 1.67 ENST00000510224.1
PROM1
prominin 1
chr1_+_228870824 1.61 ENST00000366691.3
RHOU
ras homolog family member U
chr1_-_246670519 1.59 ENST00000388985.4
ENST00000490107.1
SMYD3
SET and MYND domain containing 3
chr17_-_28257080 1.54 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr1_+_63989004 1.54 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr7_+_154720173 1.51 ENST00000397551.2
PAXIP1-AS2
PAXIP1 antisense RNA 2
chr14_+_65016620 1.50 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr2_-_86564776 1.48 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr7_+_138818490 1.48 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
TTC26
tetratricopeptide repeat domain 26
chr17_-_34890732 1.47 ENST00000268852.9
MYO19
myosin XIX
chr15_+_81426588 1.46 ENST00000286732.4
C15orf26
chromosome 15 open reading frame 26
chr3_+_32737027 1.45 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr7_+_138915102 1.44 ENST00000486663.1
UBN2
ubinuclein 2
chr5_-_146833485 1.42 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr7_-_130080977 1.41 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr12_-_95945246 1.40 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr11_+_71900572 1.40 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr6_-_110011718 1.38 ENST00000532976.1
AK9
adenylate kinase 9
chr8_-_144699668 1.35 ENST00000425753.2
TSTA3
tissue specific transplantation antigen P35B
chr8_+_1993173 1.32 ENST00000523438.1
MYOM2
myomesin 2
chr7_+_152456829 1.32 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ACTR3B
ARP3 actin-related protein 3 homolog B (yeast)
chr22_+_29168652 1.30 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr8_+_1993152 1.29 ENST00000262113.4
MYOM2
myomesin 2
chr11_+_101785727 1.24 ENST00000263468.8
KIAA1377
KIAA1377
chr7_+_90339169 1.22 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr8_-_144699628 1.19 ENST00000529048.1
ENST00000529064.1
TSTA3
tissue specific transplantation antigen P35B
chr17_-_34890759 1.19 ENST00000431794.3
MYO19
myosin XIX
chr4_-_141348999 1.17 ENST00000325617.5
CLGN
calmegin
chr19_-_44905741 1.15 ENST00000591679.1
ENST00000544719.2
ENST00000330997.4
ENST00000585868.1
ENST00000588212.1
ZNF285
CTC-512J12.6
zinc finger protein 285
Uncharacterized protein
chr1_-_216978709 1.15 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr2_+_55746746 1.12 ENST00000406691.3
ENST00000349456.4
ENST00000407816.3
ENST00000403007.3
CCDC104
coiled-coil domain containing 104
chr3_+_132036207 1.08 ENST00000336375.5
ENST00000495911.1
ACPP
acid phosphatase, prostate
chr17_+_19091325 1.06 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr6_+_32812568 1.05 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr19_-_48752812 1.03 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr18_-_53253112 1.03 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr2_-_73460334 1.03 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr2_+_39103103 1.02 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN2
MORN repeat containing 2
chr4_+_70894130 1.01 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr1_+_100818009 1.01 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr8_-_12668962 1.01 ENST00000534827.1
RP11-252C15.1
RP11-252C15.1
chr12_+_4758264 1.00 ENST00000266544.5
NDUFA9
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr11_+_7618413 1.00 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_+_21387491 0.99 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr18_-_53253323 0.99 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr22_-_20307532 0.99 ENST00000405465.3
ENST00000248879.3
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr5_-_146833222 0.99 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr19_-_48753104 0.98 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr2_+_170335924 0.95 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5
RP11-724O16.1
Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr11_+_36616044 0.95 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chr11_-_5255861 0.94 ENST00000380299.3
HBD
hemoglobin, delta
chr14_+_31028348 0.93 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr5_-_76383133 0.91 ENST00000255198.2
ZBED3
zinc finger, BED-type containing 3
chr8_-_38008783 0.90 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr5_+_93954039 0.87 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr19_+_49496705 0.87 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr4_+_146539415 0.85 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr5_+_140254884 0.84 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr7_+_150065278 0.84 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr4_-_123843597 0.82 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr8_-_42065187 0.80 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr7_+_138145145 0.79 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr4_-_110723134 0.79 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr12_+_14956506 0.78 ENST00000330828.2
C12orf60
chromosome 12 open reading frame 60
chr4_-_95264008 0.78 ENST00000295256.5
HPGDS
hematopoietic prostaglandin D synthase
chr19_-_48753028 0.77 ENST00000522431.1
CARD8
caspase recruitment domain family, member 8
chr19_-_23941680 0.76 ENST00000402377.3
ZNF681
zinc finger protein 681
chr12_-_88535747 0.76 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr5_+_140227048 0.74 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr8_-_42065075 0.73 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr19_+_21265028 0.73 ENST00000291770.7
ZNF714
zinc finger protein 714
chrX_-_77582980 0.73 ENST00000373304.3
CYSLTR1
cysteinyl leukotriene receptor 1
chr2_+_61372226 0.72 ENST00000426997.1
C2orf74
chromosome 2 open reading frame 74
chr19_-_48759119 0.72 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
CARD8
caspase recruitment domain family, member 8
chr8_+_107738240 0.71 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr7_-_99149715 0.71 ENST00000449309.1
FAM200A
family with sequence similarity 200, member A
chr5_-_146781153 0.71 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr19_+_49497121 0.71 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr11_-_104480019 0.69 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr19_+_49496782 0.69 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr6_-_31681839 0.69 ENST00000409239.1
ENST00000461287.1
LY6G6E
XXbac-BPG32J3.20
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr20_-_45142154 0.68 ENST00000347606.4
ENST00000457685.2
ZNF334
zinc finger protein 334
chr11_-_67275542 0.67 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr16_+_66914264 0.65 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr10_-_113943447 0.65 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr19_+_58281014 0.65 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
ZNF586
zinc finger protein 586
chr5_-_176433693 0.64 ENST00000507513.1
ENST00000511320.1
UIMC1
ubiquitin interaction motif containing 1
chr2_+_138721850 0.62 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr1_+_171750776 0.62 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13
methyltransferase like 13
chr15_+_66797455 0.61 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr9_+_2029019 0.60 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr18_-_19283649 0.58 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr19_+_38085731 0.58 ENST00000589117.1
ZNF540
zinc finger protein 540
chr2_-_70475730 0.58 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr17_-_34890665 0.57 ENST00000586007.1
MYO19
myosin XIX
chr19_-_22018966 0.56 ENST00000599906.1
ENST00000354959.4
ZNF43
zinc finger protein 43
chr17_-_7232585 0.56 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr11_-_796197 0.56 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_-_237416181 0.56 ENST00000409907.3
IQCA1
IQ motif containing with AAA domain 1
chr16_+_20818020 0.55 ENST00000564274.1
ENST00000563068.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr5_+_140213815 0.54 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr15_+_66797627 0.53 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr17_+_71228740 0.53 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr2_-_201753717 0.53 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr5_-_157603408 0.52 ENST00000522769.1
CTC-436K13.5
CTC-436K13.5
chr3_+_138327417 0.52 ENST00000338446.4
FAIM
Fas apoptotic inhibitory molecule
chr1_+_219347203 0.51 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr11_+_22696314 0.51 ENST00000532398.1
ENST00000433790.1
GAS2
growth arrest-specific 2
chr12_-_59175485 0.51 ENST00000550678.1
ENST00000552201.1
RP11-767I20.1
RP11-767I20.1
chr3_+_138327542 0.50 ENST00000360570.3
ENST00000393035.2
FAIM
Fas apoptotic inhibitory molecule
chr13_-_79233314 0.50 ENST00000282003.6
RNF219
ring finger protein 219
chr4_-_39367949 0.50 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr5_-_176433582 0.49 ENST00000506128.1
UIMC1
ubiquitin interaction motif containing 1
chr10_+_51549498 0.48 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr20_-_21378666 0.48 ENST00000351817.4
NKX2-4
NK2 homeobox 4
chr5_-_156569754 0.47 ENST00000420343.1
MED7
mediator complex subunit 7
chr19_+_13858593 0.47 ENST00000221554.8
CCDC130
coiled-coil domain containing 130
chr17_-_34890709 0.47 ENST00000544606.1
MYO19
myosin XIX
chr12_-_31743901 0.47 ENST00000354285.4
DENND5B
DENN/MADD domain containing 5B
chr2_-_201753859 0.47 ENST00000409361.1
ENST00000392283.4
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr3_-_108672742 0.47 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr16_+_67906919 0.46 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr14_-_39901618 0.46 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr2_+_201754050 0.46 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr2_-_201753980 0.46 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr11_-_5173599 0.46 ENST00000328942.1
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr4_-_156298087 0.45 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr9_+_91933726 0.44 ENST00000534113.2
SECISBP2
SECIS binding protein 2
chr10_-_52383644 0.44 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr11_-_32457075 0.44 ENST00000448076.3
WT1
Wilms tumor 1
chr22_+_18893736 0.44 ENST00000331444.6
DGCR6
DiGeorge syndrome critical region gene 6
chr14_-_70826438 0.43 ENST00000389912.6
COX16
COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr2_-_152146385 0.43 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr14_+_55494323 0.43 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr1_+_146714291 0.42 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr7_+_35756186 0.42 ENST00000430518.1
AC018647.3
AC018647.3
chr19_+_21579908 0.41 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr19_-_48753064 0.41 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
CARD8
caspase recruitment domain family, member 8
chr2_+_138722028 0.41 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr4_-_69536346 0.40 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr15_-_55657428 0.40 ENST00000568543.1
CCPG1
cell cycle progression 1
chr1_+_166958497 0.40 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr10_-_70287231 0.40 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr3_-_179322416 0.39 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr12_+_70219052 0.39 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr9_+_137979506 0.39 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr1_+_158975744 0.39 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr3_+_179322481 0.38 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr3_+_137906109 0.38 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8
armadillo repeat containing 8
chr8_-_92053212 0.38 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr7_-_112758589 0.38 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
LINC00998
long intergenic non-protein coding RNA 998
chr22_+_22676808 0.38 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr7_+_138145076 0.37 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr12_+_108525517 0.37 ENST00000332082.4
WSCD2
WSC domain containing 2
chr19_-_14945933 0.37 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr10_+_6625605 0.37 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr3_-_179322436 0.36 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr15_+_72410629 0.36 ENST00000340912.4
ENST00000544171.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr16_+_16484691 0.36 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr9_+_134065506 0.36 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr17_-_60883993 0.36 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr7_+_64838712 0.36 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr19_-_38085633 0.36 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr2_+_201754135 0.36 ENST00000409357.1
ENST00000409129.2
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr19_-_45996465 0.35 ENST00000430715.2
RTN2
reticulon 2
chr1_+_219347186 0.35 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr7_+_141811539 0.35 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chr11_+_60048004 0.35 ENST00000532114.1
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr4_-_100140331 0.34 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr11_-_26593677 0.34 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr3_-_56502375 0.34 ENST00000288221.6
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr8_+_77318769 0.34 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr2_+_132160448 0.34 ENST00000437751.1
AC073869.19
long intergenic non-protein coding RNA 1120
chr10_+_24755416 0.34 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.8 2.5 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.8 3.3 GO:0003095 pressure natriuresis(GO:0003095)
0.5 1.4 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.5 1.4 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.5 2.3 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.4 4.9 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 12.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.3 1.0 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.3 2.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 0.9 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.2 3.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2 0.9 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.2 31.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 1.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 1.0 GO:0001692 histamine metabolic process(GO:0001692)
0.2 1.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.2 1.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 0.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 5.3 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 3.1 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 2.2 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1 0.7 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 0.7 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 3.3 GO:0003341 cilium movement(GO:0003341)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 3.0 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 0.8 GO:0048793 pronephros development(GO:0048793)
0.1 0.3 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.1 3.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.4 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.5 GO:0031639 plasminogen activation(GO:0031639)
0.1 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.5 GO:0035973 aggrephagy(GO:0035973)
0.1 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.9 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 1.0 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.9 GO:0015671 oxygen transport(GO:0015671)
0.0 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 1.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.6 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 1.5 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 1.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 1.0 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.0 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.0 0.1 GO:0071038 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 33.5 GO:0005844 polysome(GO:0005844)
0.3 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.1 GO:1990423 RZZ complex(GO:1990423)
0.2 1.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 3.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 2.3 GO:0097255 R2TP complex(GO:0097255)
0.2 3.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 3.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.9 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 2.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0060091 kinocilium(GO:0060091)
0.1 1.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 0.2 GO:0030849 autosome(GO:0030849)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 3.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 3.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.0 3.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.7 GO:0002102 podosome(GO:0002102)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.7 3.9 GO:0032089 NACHT domain binding(GO:0032089)
0.4 3.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.4 32.7 GO:0019843 rRNA binding(GO:0019843)
0.4 1.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 2.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 1.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 1.0 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.3 2.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3 3.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 0.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 1.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 2.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 3.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.7 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.8 GO:0032052 bile acid binding(GO:0032052)
0.1 0.3 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 2.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 3.5 GO:0042805 actinin binding(GO:0042805)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 2.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.2 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0019784 SUMO-specific protease activity(GO:0016929) NEDD8-specific protease activity(GO:0019784)
0.0 1.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 2.4 GO:0016853 isomerase activity(GO:0016853)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.3 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 32.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 5.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 6.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 4.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis