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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXC13

Z-value: 0.79

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
ENSG00000123364.3 homeobox C13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_54332636-0.561.5e-03Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_88117683 2.41 ENST00000369562.4
UPF0704 protein C6orf165
chr1_-_47407097 2.04 ENST00000457840.2
cytochrome P450, family 4, subfamily A, polypeptide 11
chr1_-_109656439 1.96 ENST00000369949.4
chromosome 1 open reading frame 194
chr13_-_20077417 1.75 ENST00000382978.1
ENST00000400230.2
ENST00000255310.6
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr15_+_71228826 1.59 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
leucine rich repeat containing 49
chr10_+_51549498 1.53 ENST00000358559.2
ENST00000298239.6
microseminoprotein, beta-
chr4_+_70861647 1.19 ENST00000246895.4
ENST00000381060.2
statherin
chr15_+_71184931 1.16 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr4_-_147866960 1.15 ENST00000513335.1
tetratricopeptide repeat domain 29
chr15_+_71185148 1.08 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr17_-_39165366 1.06 ENST00000391588.1
keratin associated protein 3-1
chr4_-_150736962 0.98 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
chr1_+_246887349 0.97 ENST00000366510.3
saccharopine dehydrogenase (putative)
chr7_-_69062391 0.95 ENST00000436600.2
RP5-942I16.1
chr6_+_19837592 0.88 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr17_-_39140549 0.87 ENST00000377755.4
keratin 40
chr7_+_138915102 0.84 ENST00000486663.1
ubinuclein 2
chr4_+_95679072 0.83 ENST00000515059.1
bone morphogenetic protein receptor, type IB
chr12_-_91539918 0.83 ENST00000548218.1
decorin
chr19_+_38085731 0.82 ENST00000589117.1
zinc finger protein 540
chr6_+_127898312 0.81 ENST00000329722.7
chromosome 6 open reading frame 58
chr4_-_148605265 0.81 ENST00000541232.1
ENST00000322396.6
protein arginine methyltransferase 10 (putative)
chr6_-_46922659 0.79 ENST00000265417.7
G protein-coupled receptor 116
chr18_-_10748498 0.79 ENST00000579949.1
piezo-type mechanosensitive ion channel component 2
chr14_-_68000442 0.78 ENST00000554278.1
transmembrane protein 229B
chr6_-_33041378 0.75 ENST00000428995.1
major histocompatibility complex, class II, DP alpha 1
chr1_+_171107241 0.75 ENST00000236166.3
flavin containing monooxygenase 6 pseudogene
chr1_+_47533160 0.72 ENST00000334194.3
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr5_-_41261540 0.72 ENST00000263413.3
complement component 6
chr7_-_92777606 0.70 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr2_+_89986318 0.65 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr6_-_76782371 0.65 ENST00000369950.3
ENST00000369963.3
interphotoreceptor matrix proteoglycan 1
chr18_-_74839891 0.65 ENST00000581878.1
myelin basic protein
chr17_+_3118915 0.64 ENST00000304094.1
olfactory receptor, family 1, subfamily A, member 1
chr1_-_149832704 0.64 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
histone cluster 2, H4b
chr5_+_140248518 0.63 ENST00000398640.2
protocadherin alpha 11
chr3_+_129159039 0.62 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
intraflagellar transport 122 homolog (Chlamydomonas)
chr5_+_140180635 0.61 ENST00000522353.2
ENST00000532566.2
protocadherin alpha 3
chrX_-_38186775 0.61 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
retinitis pigmentosa GTPase regulator
chr12_-_89413456 0.61 ENST00000500381.2
RP11-13A1.1
chr1_+_43766642 0.59 ENST00000372476.3
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr9_+_137979506 0.57 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
olfactomedin 1
chr11_+_118175132 0.57 ENST00000361763.4
CD3e molecule, epsilon (CD3-TCR complex)
chr15_-_78538025 0.57 ENST00000560817.1
acyl-CoA synthetase bubblegum family member 1
chr11_+_101785727 0.57 ENST00000263468.8
KIAA1377
chr6_-_112080256 0.56 ENST00000462856.2
ENST00000229471.4
FYN oncogene related to SRC, FGR, YES
chr17_+_17685422 0.56 ENST00000395774.1
retinoic acid induced 1
chr8_+_101170563 0.56 ENST00000520508.1
ENST00000388798.2
sperm associated antigen 1
chr10_-_13544945 0.55 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr1_+_149804218 0.52 ENST00000610125.1
histone cluster 2, H4a
chr6_-_49681235 0.52 ENST00000339139.4
cysteine-rich secretory protein 2
chr6_-_11807277 0.51 ENST00000379415.2
androgen-dependent TFPI-regulating protein
chr6_-_32784687 0.50 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr15_-_76304731 0.48 ENST00000394907.3
neuregulin 4
chr1_+_166958346 0.48 ENST00000367872.4
maelstrom spermatogenic transposon silencer
chr1_-_198990166 0.48 ENST00000427439.1
RP11-16L9.3
chr9_-_88715044 0.48 ENST00000388711.3
ENST00000466178.1
golgi membrane protein 1
chr5_-_79287060 0.47 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
metaxin 3
chr6_-_52628271 0.47 ENST00000493422.1
glutathione S-transferase alpha 2
chr9_-_32526299 0.46 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_+_70894130 0.45 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
histatin 3
chr17_-_10707410 0.45 ENST00000581851.1
long intergenic non-protein coding RNA 675
chr12_-_13248598 0.43 ENST00000337630.6
ENST00000545699.1
germ cell associated 1
chr7_+_6797288 0.42 ENST00000433859.2
ENST00000359718.3
radial spoke head 10 homolog B2 (Chlamydomonas)
chr1_+_174844645 0.42 ENST00000486220.1
RAB GTPase activating protein 1-like
chr4_+_70146217 0.42 ENST00000335568.5
ENST00000511240.1
UDP glucuronosyltransferase 2 family, polypeptide B28
chr9_-_139137648 0.42 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr6_-_130031358 0.41 ENST00000368149.2
Rho GTPase activating protein 18
chr8_+_118147498 0.40 ENST00000519688.1
ENST00000456015.2
solute carrier family 30 (zinc transporter), member 8
chr17_-_28257080 0.40 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
slingshot protein phosphatase 2
chr17_-_2415169 0.39 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
methyltransferase like 16
chr3_-_123339343 0.39 ENST00000578202.1
myosin light chain kinase
chr3_-_123339418 0.38 ENST00000583087.1
myosin light chain kinase
chr5_-_180076580 0.38 ENST00000502649.1
fms-related tyrosine kinase 4
chr9_+_86238016 0.38 ENST00000530832.1
ENST00000405990.3
ENST00000376417.4
ENST00000376419.4
idnK, gluconokinase homolog (E. coli)
chr17_+_35732955 0.38 ENST00000300618.4
chromosome 17 open reading frame 78
chr12_-_9360966 0.37 ENST00000261336.2
pregnancy-zone protein
chr1_+_179050512 0.37 ENST00000367627.3
torsin family 3, member A
chr1_+_174128639 0.36 ENST00000251507.4
RAB GTPase activating protein 1-like
chr3_+_148508845 0.36 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr2_+_61372226 0.36 ENST00000426997.1
chromosome 2 open reading frame 74
chr5_+_110409012 0.36 ENST00000379706.4
thymic stromal lymphopoietin
chr7_-_152373216 0.35 ENST00000359321.1
X-ray repair complementing defective repair in Chinese hamster cells 2
chr3_+_148545586 0.34 ENST00000282957.4
ENST00000468341.1
carboxypeptidase B1 (tissue)
chr9_+_21967137 0.34 ENST00000441769.2
chromosome 9 open reading frame 53
chr9_-_88714421 0.34 ENST00000388712.3
golgi membrane protein 1
chr7_+_80275621 0.34 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr10_-_113943447 0.34 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
glycerol-3-phosphate acyltransferase, mitochondrial
chr5_+_101569696 0.33 ENST00000597120.1
AC008948.1
chr1_+_174128536 0.33 ENST00000357444.6
ENST00000367689.3
RAB GTPase activating protein 1-like
chr7_+_80275752 0.33 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr15_-_44069741 0.32 ENST00000319359.3
elongation factor RNA polymerase II-like 3
chr14_-_24911868 0.32 ENST00000554698.1
short chain dehydrogenase/reductase family 39U, member 1
chr19_-_35719609 0.32 ENST00000324675.3
family with sequence similarity 187, member B
chr17_+_35732916 0.31 ENST00000586700.1
chromosome 17 open reading frame 78
chr13_+_34392200 0.31 ENST00000434425.1
replication factor C (activator 1) 3, 38kDa
chr18_-_24722995 0.31 ENST00000581714.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr3_-_195310802 0.31 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr5_-_74532696 0.31 ENST00000506364.2
ENST00000274361.3
ankyrin repeat domain 31
chr8_-_95274536 0.30 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr6_+_88182643 0.30 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr15_-_58571445 0.30 ENST00000558231.1
aldehyde dehydrogenase 1 family, member A2
chr7_+_80275953 0.29 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr11_+_49050504 0.29 ENST00000332682.7
tripartite motif containing 49B
chr8_-_10512569 0.29 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr11_+_30252549 0.28 ENST00000254122.3
ENST00000417547.1
follicle stimulating hormone, beta polypeptide
chr10_+_118187379 0.28 ENST00000369230.3
pancreatic lipase-related protein 3
chr2_-_177502254 0.28 ENST00000339037.3
long intergenic non-protein coding RNA 1116
chr8_+_77318769 0.27 ENST00000518732.1
long intergenic non-protein coding RNA 1111
chr9_-_74675521 0.27 ENST00000377024.3
chromosome 9 open reading frame 57
chr1_-_112106556 0.27 ENST00000443498.1
adenosine A3 receptor
chr3_-_51909600 0.26 ENST00000446461.1
IQ motif containing F5
chr19_-_11456905 0.26 ENST00000588560.1
ENST00000592952.1
transmembrane protein 205
chr1_-_86174065 0.25 ENST00000370574.3
ENST00000431532.2
zinc finger, HIT-type containing 6
chr17_-_46806540 0.25 ENST00000290295.7
homeobox B13
chr19_-_11456872 0.25 ENST00000586218.1
transmembrane protein 205
chr16_-_2379688 0.25 ENST00000567910.1
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_+_7011509 0.25 ENST00000377296.3
Uncharacterized protein
chr19_+_3762645 0.25 ENST00000330133.4
mitochondrial ribosomal protein L54
chr16_+_16481598 0.24 ENST00000327792.5
nuclear pore complex interacting protein family, member A7
chr19_-_11457082 0.24 ENST00000587948.1
transmembrane protein 205
chr19_+_38085768 0.24 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
zinc finger protein 540
chr19_-_11456722 0.24 ENST00000354882.5
transmembrane protein 205
chr19_-_11457162 0.24 ENST00000590482.1
transmembrane protein 205
chr17_+_29664830 0.24 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr4_+_170581213 0.24 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr11_-_104480019 0.24 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chr12_-_4647606 0.23 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
chromosome 12 open reading frame 4
chr6_+_20534672 0.22 ENST00000274695.4
ENST00000378624.4
CDK5 regulatory subunit associated protein 1-like 1
chr5_-_58571935 0.22 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr22_+_23101182 0.21 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr14_-_50065882 0.21 ENST00000539688.1
Full-length cDNA clone CS0DK012YO09 of HeLa cells of Homo sapiens (human); Uncharacterized protein
chr8_+_95565947 0.21 ENST00000523011.1
RP11-267M23.4
chrX_+_139791917 0.20 ENST00000607004.1
ENST00000370535.3
long intergenic non-protein coding RNA 632
chr19_-_38085633 0.20 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
zinc finger protein 571
chr14_-_106963409 0.20 ENST00000390621.2
immunoglobulin heavy variable 1-45
chrX_-_135338503 0.20 ENST00000370663.5
MAP7 domain containing 3
chr5_+_5140436 0.20 ENST00000511368.1
ENST00000274181.7
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr14_-_50319482 0.20 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
nuclear export mediator factor
chr1_-_112106578 0.20 ENST00000369717.4
adenosine A3 receptor
chr18_-_52989525 0.20 ENST00000457482.3
transcription factor 4
chr5_+_42756903 0.19 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr14_-_50319758 0.19 ENST00000298310.5
nuclear export mediator factor
chr8_+_133879193 0.19 ENST00000377869.1
ENST00000220616.4
thyroglobulin
chr2_+_103035102 0.19 ENST00000264260.2
interleukin 18 receptor accessory protein
chr3_+_122513642 0.19 ENST00000261038.5
disrupted in renal carcinoma 2
chr1_-_85097431 0.19 ENST00000327308.3
chromosome 1 open reading frame 180
chr12_-_54689532 0.19 ENST00000540264.2
ENST00000312156.4
nuclear factor, erythroid 2
chr19_+_16999654 0.18 ENST00000248076.3
coagulation factor II (thrombin) receptor-like 3
chr2_-_234475380 0.18 ENST00000443711.2
ENST00000251722.6
ubiquitin specific peptidase 40
chr1_-_153123345 0.17 ENST00000368748.4
small proline-rich protein 2G
chr13_-_95131923 0.17 ENST00000377028.5
ENST00000446125.1
dopachrome tautomerase
chr1_-_168464875 0.17 ENST00000422253.1
RP5-968D22.3
chr10_+_18240834 0.17 ENST00000377371.3
ENST00000539911.1
solute carrier family 39 (zinc transporter), member 12
chr12_-_9885888 0.17 ENST00000327839.3
C-type lectin-like 1
chr2_-_225811747 0.17 ENST00000409592.3
dedicator of cytokinesis 10
chr22_-_19435209 0.17 ENST00000546308.1
ENST00000541063.1
ENST00000399568.1
ENST00000333059.5
histone cell cycle regulator
chromosome 22 open reading frame 39
chr4_+_48485341 0.16 ENST00000273861.4
solute carrier family 10, member 4
chrX_+_133733457 0.16 ENST00000440614.1
RP11-308B5.2
chr19_-_6279932 0.16 ENST00000252674.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr9_-_5304432 0.16 ENST00000416837.1
ENST00000308420.3
relaxin 2
chr5_-_169725231 0.16 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr21_+_43823983 0.16 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr3_-_46037299 0.16 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chr10_-_48055018 0.16 ENST00000426610.2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2C
chr6_-_150217195 0.15 ENST00000532335.1
retinoic acid early transcript 1E
chr7_+_23749767 0.15 ENST00000355870.3
serine/threonine kinase 31
chr7_+_23749945 0.15 ENST00000354639.3
ENST00000531170.1
ENST00000444333.2
ENST00000428484.1
serine/threonine kinase 31
chr5_+_134181625 0.15 ENST00000394976.3
chromosome 5 open reading frame 24
chr1_-_89591749 0.15 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr21_+_25801041 0.15 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr9_-_2844058 0.14 ENST00000397885.2
KIAA0020
chr8_+_1993152 0.14 ENST00000262113.4
myomesin 2
chr8_+_1993173 0.14 ENST00000523438.1
myomesin 2
chr7_-_4877677 0.14 ENST00000538469.1
Ras association and DIL domains
chr6_-_51952418 0.14 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr2_+_27498289 0.14 ENST00000296097.3
ENST00000420191.1
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
chr17_+_19091325 0.13 ENST00000584923.1
small nucleolar RNA, C/D box 3A
chr4_+_110749143 0.13 ENST00000317735.4
retinal pigment epithelium-derived rhodopsin homolog
chr17_+_43861680 0.13 ENST00000314537.5
corticotropin releasing hormone receptor 1
chr1_+_90460661 0.13 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
zinc finger protein 326
chr15_+_77224045 0.12 ENST00000320963.5
ENST00000394883.3
reticulocalbin 2, EF-hand calcium binding domain
chr15_+_77223960 0.12 ENST00000394885.3
reticulocalbin 2, EF-hand calcium binding domain
chr7_-_64023441 0.12 ENST00000309683.6
zinc finger protein 680
chrX_+_49687216 0.12 ENST00000376088.3
chloride channel, voltage-sensitive 5
chr16_-_72206034 0.12 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr5_+_150020214 0.12 ENST00000307662.4
synaptopodin
chr1_+_222886694 0.11 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BRO1 domain and CAAX motif containing
chr12_-_52828147 0.11 ENST00000252245.5
keratin 75
chr8_-_86290333 0.11 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr20_+_36946029 0.11 ENST00000417318.1
bactericidal/permeability-increasing protein
chr11_+_62037622 0.11 ENST00000227918.2
ENST00000525380.1
secretoglobin, family 2A, member 2
chr10_+_18240814 0.11 ENST00000377374.4
solute carrier family 39 (zinc transporter), member 12
chr9_+_103947311 0.10 ENST00000395056.2
Lipid phosphate phosphatase-related protein type 1
chr20_-_52687059 0.10 ENST00000371435.2
ENST00000395961.3
breast carcinoma amplified sequence 1
chr2_-_223520770 0.10 ENST00000536361.1
phenylalanyl-tRNA synthetase, beta subunit
chr2_-_86850949 0.10 ENST00000237455.4
ring finger protein 103
chr14_+_37641012 0.10 ENST00000556667.1
SLC25A21 antisense RNA 1
chr22_+_39916558 0.10 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr3_+_185080908 0.10 ENST00000265026.3
mitogen-activated protein kinase kinase kinase 13

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0003095 pressure natriuresis(GO:0003095)
0.2 0.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 0.9 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.2 0.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 0.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 1.0 GO:0072564 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.4 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.6 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.2 GO:0046541 saliva secretion(GO:0046541)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.6 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.4 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.8 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.0 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.6 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030849 autosome(GO:0030849)
0.1 0.3 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.4 1.8 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.4 1.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.2 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.6 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.0 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis