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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXD10

Z-value: 0.97

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Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
HOXD10
ENSG00000128710.5 homeobox D10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD10hg19_v2_chr2_+_176981307_176981307-0.202.9e-01Click!

Activity profile of HOXD10 motif

Sorted Z-values of HOXD10 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_96211643 2.64 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr4_-_68749745 2.40 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr1_+_152975488 2.37 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr1_-_153113927 2.14 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr4_-_68749699 2.11 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr18_+_29027696 1.87 ENST00000257189.4
DSG3
desmoglein 3
chr10_-_28623368 1.76 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_-_214016314 1.50 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr4_-_47983519 1.49 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr13_+_78109884 1.34 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr8_+_39770803 1.34 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr13_+_78109804 1.32 ENST00000535157.1
SCEL
sciellin
chr7_+_132333553 1.24 ENST00000332558.4
AC009365.3
AC009365.3
chr1_+_62439037 1.18 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr15_+_41549105 1.14 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr18_+_61445007 1.12 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr7_+_76054224 1.08 ENST00000394857.3
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr2_-_161056762 1.07 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr9_-_21142144 1.03 ENST00000380229.2
IFNW1
interferon, omega 1
chr2_-_190044480 0.95 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr6_+_37897735 0.95 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr4_+_40198527 0.94 ENST00000381799.5
RHOH
ras homolog family member H
chr9_+_75263565 0.92 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr12_-_91576561 0.92 ENST00000547568.2
ENST00000552962.1
DCN
decorin
chr2_+_90458201 0.91 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr7_-_111032971 0.91 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr19_-_51456321 0.89 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr12_-_25055177 0.87 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr3_+_169629354 0.86 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr12_+_8309630 0.84 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr6_+_42018614 0.84 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr11_-_19082216 0.83 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr2_+_135011731 0.82 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr12_-_48164812 0.80 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr6_+_147527103 0.79 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr12_-_92536433 0.79 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr14_+_67291158 0.78 ENST00000555456.1
GPHN
gephyrin
chr22_-_50524298 0.75 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_+_57882024 0.74 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr4_+_187148556 0.74 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr2_-_161056802 0.74 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr20_+_59654146 0.74 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr17_-_38938786 0.73 ENST00000301656.3
KRT27
keratin 27
chr14_+_22615942 0.73 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr16_-_20681177 0.71 ENST00000524149.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr2_-_165698662 0.71 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr6_+_20534672 0.70 ENST00000274695.4
ENST00000378624.4
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr4_+_71063641 0.70 ENST00000514097.1
ODAM
odontogenic, ameloblast asssociated
chr1_+_192127578 0.68 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr6_+_166945369 0.67 ENST00000598601.1
Z98049.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr11_+_133938820 0.67 ENST00000299106.4
ENST00000529443.2
JAM3
junctional adhesion molecule 3
chr9_+_75229616 0.67 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr12_-_12674032 0.66 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chrX_+_15808569 0.66 ENST00000380308.3
ENST00000307771.7
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr13_-_47012325 0.65 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr2_+_196313239 0.65 ENST00000413290.1
AC064834.1
AC064834.1
chr10_+_98064085 0.63 ENST00000419175.1
ENST00000371174.2
DNTT
DNA nucleotidylexotransferase
chr10_+_96443378 0.63 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr15_-_55562479 0.63 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr2_-_211341411 0.63 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LANCL1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr8_-_131399110 0.62 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr12_-_10324716 0.61 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr4_-_89951028 0.61 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr3_-_195310802 0.58 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr5_-_135290705 0.58 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr6_-_130543958 0.58 ENST00000437477.2
ENST00000439090.2
SAMD3
sterile alpha motif domain containing 3
chr5_-_39203093 0.55 ENST00000515010.1
FYB
FYN binding protein
chr17_-_2966901 0.55 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr6_+_121756809 0.54 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr11_-_64647144 0.54 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EHD1
EH-domain containing 1
chr4_-_70080449 0.54 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr8_-_101719159 0.54 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr2_+_101437487 0.52 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr5_+_140227357 0.52 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr14_+_51955831 0.51 ENST00000356218.4
FRMD6
FERM domain containing 6
chr12_-_13248598 0.51 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr13_+_114567131 0.50 ENST00000608651.1
GAS6-AS2
GAS6 antisense RNA 2 (head to head)
chr18_+_48918368 0.50 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
RP11-267C16.1
chr6_-_150067696 0.50 ENST00000340413.2
ENST00000367403.3
NUP43
nucleoporin 43kDa
chr3_-_99569821 0.49 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr9_-_74675521 0.49 ENST00000377024.3
C9orf57
chromosome 9 open reading frame 57
chr2_-_86333244 0.49 ENST00000263857.6
ENST00000409681.1
POLR1A
polymerase (RNA) I polypeptide A, 194kDa
chr3_-_37216055 0.49 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr7_-_108168580 0.49 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr9_+_82187487 0.49 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_+_132937820 0.48 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr3_-_27498235 0.48 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr18_+_23713808 0.48 ENST00000415576.2
ENST00000343848.6
ENST00000308268.6
PSMA8
proteasome (prosome, macropain) subunit, alpha type, 8
chr9_-_93405352 0.48 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr12_+_21525818 0.48 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr2_+_102456277 0.47 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr10_+_11047259 0.47 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr15_+_69373184 0.47 ENST00000558147.1
ENST00000440444.1
LINC00277
long intergenic non-protein coding RNA 277
chr7_+_135611542 0.46 ENST00000416501.1
AC015987.2
AC015987.2
chr9_+_82187630 0.46 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_-_49965663 0.46 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4
A kinase (PRKA) anchor protein 4
chr1_+_74701062 0.45 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr7_+_107224364 0.43 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr1_-_95391315 0.43 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr12_-_91546926 0.43 ENST00000550758.1
DCN
decorin
chr3_+_30647994 0.43 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr9_-_4666421 0.43 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr2_+_210444748 0.43 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr8_+_62200509 0.42 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr6_+_27791862 0.42 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chr3_-_120461353 0.42 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chr4_-_76944621 0.41 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr9_-_116163400 0.41 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD
aminolevulinate dehydratase
chr2_+_90211643 0.41 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr22_-_29107919 0.40 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr6_-_137494775 0.40 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
IL22RA2
interleukin 22 receptor, alpha 2
chr8_+_7801144 0.40 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr4_+_166300084 0.40 ENST00000402744.4
CPE
carboxypeptidase E
chrX_-_41449204 0.40 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr4_+_118955500 0.40 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr17_-_38911580 0.40 ENST00000312150.4
KRT25
keratin 25
chr3_+_30648066 0.40 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr2_+_68961934 0.39 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr9_+_34329493 0.39 ENST00000379158.2
ENST00000346365.4
ENST00000379155.5
NUDT2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr16_-_30122717 0.39 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr2_-_29297127 0.39 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr3_-_128206759 0.39 ENST00000430265.2
GATA2
GATA binding protein 2
chr3_+_57881966 0.38 ENST00000495364.1
SLMAP
sarcolemma associated protein
chrX_+_37639302 0.38 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr11_-_130786333 0.38 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr3_+_136676707 0.37 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr12_-_118797475 0.37 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr9_+_82188077 0.37 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_-_53770972 0.37 ENST00000311170.4
VN1R4
vomeronasal 1 receptor 4
chr3_+_186435137 0.37 ENST00000447445.1
KNG1
kininogen 1
chr2_+_68961905 0.37 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr6_-_135375986 0.36 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1L
HBS1-like (S. cerevisiae)
chr5_+_39105358 0.36 ENST00000593965.1
AC008964.1
AC008964.1
chr7_+_106505912 0.36 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_+_117963209 0.36 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr9_+_4839762 0.36 ENST00000448872.2
ENST00000441844.1
RCL1
RNA terminal phosphate cyclase-like 1
chr14_+_22265444 0.35 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr7_+_134551583 0.35 ENST00000435928.1
CALD1
caldesmon 1
chr15_+_71389281 0.35 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr2_+_90273679 0.35 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr2_-_99870744 0.35 ENST00000409238.1
ENST00000423800.1
LYG2
lysozyme G-like 2
chr10_+_116697946 0.35 ENST00000298746.3
TRUB1
TruB pseudouridine (psi) synthase family member 1
chr6_-_25830785 0.34 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chrX_+_12924732 0.34 ENST00000218032.6
ENST00000311912.5
TLR8
toll-like receptor 8
chr19_-_44388116 0.34 ENST00000587539.1
ZNF404
zinc finger protein 404
chr13_+_30510003 0.34 ENST00000400540.1
LINC00544
long intergenic non-protein coding RNA 544
chr12_-_3862245 0.34 ENST00000252322.1
ENST00000440314.2
EFCAB4B
EF-hand calcium binding domain 4B
chr2_-_90538397 0.34 ENST00000443397.3
RP11-685N3.1
Uncharacterized protein
chr1_-_242612779 0.34 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr16_+_30751953 0.33 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr12_-_10022735 0.33 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr8_+_53850991 0.33 ENST00000331251.3
NPBWR1
neuropeptides B/W receptor 1
chr3_+_130569592 0.33 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr17_+_15604513 0.33 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr16_-_15180257 0.32 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr6_-_150067632 0.32 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
NUP43
nucleoporin 43kDa
chr10_+_120967072 0.32 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr7_-_107443652 0.32 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr3_+_140981456 0.32 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr9_+_42671887 0.32 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr12_+_18891045 0.32 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr2_+_157330081 0.32 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr6_-_29324054 0.31 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr9_+_125376948 0.31 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr5_-_64064508 0.31 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr1_-_232598163 0.31 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr12_-_76817036 0.31 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr4_-_153332886 0.31 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chrX_+_37639264 0.30 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr9_-_4666337 0.30 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr16_-_79015739 0.30 ENST00000594986.1
PIH1
HCG1979943; Uncharacterized protein
chr2_+_87565634 0.30 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr1_+_62417957 0.29 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr12_+_48876275 0.28 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr2_-_165424973 0.28 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr18_+_616672 0.28 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chrX_-_154493791 0.27 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chr1_-_155942086 0.27 ENST00000368315.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr6_-_160679905 0.27 ENST00000366953.3
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr8_+_42873548 0.27 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr17_-_10276319 0.27 ENST00000252172.4
ENST00000418404.3
MYH13
myosin, heavy chain 13, skeletal muscle
chr4_-_76928641 0.27 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr15_+_26360970 0.27 ENST00000556159.1
ENST00000557523.1
LINC00929
long intergenic non-protein coding RNA 929
chr2_+_183580954 0.27 ENST00000264065.7
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr6_+_72926145 0.26 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr14_+_72399114 0.26 ENST00000553525.1
ENST00000555571.1
RGS6
regulator of G-protein signaling 6
chr6_-_2751146 0.26 ENST00000268446.5
ENST00000274643.7
MYLK4
myosin light chain kinase family, member 4
chr3_+_196466710 0.26 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr11_+_120973375 0.26 ENST00000264037.2
TECTA
tectorin alpha
chr9_+_70856397 0.25 ENST00000360171.6
CBWD3
COBW domain containing 3
chr5_-_77590480 0.25 ENST00000519295.1
ENST00000255194.6
AP3B1
adaptor-related protein complex 3, beta 1 subunit
chr6_+_36097992 0.25 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr11_+_18433840 0.25 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr16_-_71610985 0.25 ENST00000355962.4
TAT
tyrosine aminotransferase
chr4_+_76481258 0.25 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr11_-_104827425 0.25 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr21_-_27423339 0.25 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr22_+_29469012 0.24 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr5_+_122181128 0.24 ENST00000261369.4
SNX24
sorting nexin 24
chr12_-_91451758 0.24 ENST00000266719.3
KERA
keratocan

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.3 1.3 GO:0036269 swimming behavior(GO:0036269)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 0.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 1.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 0.8 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.3 1.6 GO:0060005 vestibular reflex(GO:0060005)
0.3 0.8 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.7 GO:0018874 benzoate metabolic process(GO:0018874)
0.2 0.8 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 0.4 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.2 1.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 0.5 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 0.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.2 1.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 0.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.9 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.9 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.1 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.4 GO:0070541 response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
0.1 0.7 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.7 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.7 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.4 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.1 1.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.2 GO:0030820 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
0.1 0.5 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 4.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.5 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.1 1.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.2 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 4.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.5 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.5 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 1.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.7 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 3.0 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.5 GO:0051775 response to redox state(GO:0051775)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 1.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 1.8 GO:0045576 mast cell activation(GO:0045576)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 2.8 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.1 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.0 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:1904646 cellular response to beta-amyloid(GO:1904646)
0.0 0.6 GO:0042311 vasodilation(GO:0042311)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.2 2.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 9.3 GO:0001533 cornified envelope(GO:0001533)
0.1 0.9 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 1.6 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.8 GO:0089701 U2AF(GO:0089701)
0.1 0.5 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.7 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0000791 euchromatin(GO:0000791)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.3 0.8 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.8 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.9 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.3 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.1 GO:0032190 manganese ion transmembrane transporter activity(GO:0005384) acrosin binding(GO:0032190)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.4 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.2 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.3 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.5 GO:0031013 troponin I binding(GO:0031013)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.6 GO:0043295 glutathione binding(GO:0043295)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 6.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 3.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis