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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HOXD11_HOXA11

Z-value: 0.87

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Transcription factors associated with HOXD11_HOXA11

Gene Symbol Gene ID Gene Info
HOXD11
ENSG00000128713.11 homeobox D11
HOXA11
ENSG00000005073.5 homeobox A11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD11hg19_v2_chr2_+_176972000_1769720250.251.9e-01Click!
HOXA11hg19_v2_chr7_-_27224795_27224840,
hg19_v2_chr7_-_27224842_27224872		-0.154.2e-01Click!

Activity profile of HOXD11_HOXA11 motif

Sorted Z-values of HOXD11_HOXA11 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_216300784 2.57 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr21_-_31869451 2.15 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr20_+_30102231 2.03 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chr10_+_118187379 1.94 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr2_+_158114051 1.85 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr4_+_169013666 1.78 ENST00000359299.3
ANXA10
annexin A10
chr5_-_39270725 1.69 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr4_-_68749699 1.68 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr11_+_76745385 1.61 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr1_+_62439037 1.59 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr6_+_12290586 1.56 ENST00000379375.5
EDN1
endothelin 1
chr7_-_41742697 1.53 ENST00000242208.4
INHBA
inhibin, beta A
chr12_-_25055177 1.48 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr5_+_7654057 1.45 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr4_-_68749745 1.39 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr9_-_21305312 1.25 ENST00000259555.4
IFNA5
interferon, alpha 5
chr10_+_102222798 1.20 ENST00000343737.5
WNT8B
wingless-type MMTV integration site family, member 8B
chr8_-_125486755 1.20 ENST00000499418.2
ENST00000530778.1
RNF139-AS1
RNF139 antisense RNA 1 (head to head)
chr7_+_134464376 1.20 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr21_-_31859755 1.15 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr7_+_134464414 1.14 ENST00000361901.2
CALD1
caldesmon 1
chr13_-_103719196 1.12 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_138915102 1.10 ENST00000486663.1
UBN2
ubinuclein 2
chrX_-_73072534 1.09 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr3_+_140981456 1.00 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr8_+_118147498 0.99 ENST00000519688.1
ENST00000456015.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr12_-_95510743 0.99 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr19_-_53636125 0.98 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
ZNF415
zinc finger protein 415
chr18_-_12656715 0.91 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr2_+_31456874 0.89 ENST00000541626.1
EHD3
EH-domain containing 3
chr7_+_80275953 0.87 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr9_+_12693336 0.87 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr7_+_79998864 0.86 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr17_+_7211656 0.86 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr20_+_37554955 0.85 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr4_+_86525299 0.84 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr5_+_148521381 0.83 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr2_-_31440377 0.83 ENST00000444918.2
ENST00000403897.3
CAPN14
calpain 14
chr7_+_40174565 0.80 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10
succinylCoA:glutarate-CoA transferase
chr10_-_103599591 0.78 ENST00000348850.5
KCNIP2
Kv channel interacting protein 2
chr9_+_105757590 0.74 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr19_-_10420459 0.74 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr18_-_5396271 0.74 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr1_+_84630645 0.71 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_103998439 0.71 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr8_+_66955648 0.70 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr1_+_153004800 0.69 ENST00000392661.3
SPRR1B
small proline-rich protein 1B
chr17_-_39646116 0.69 ENST00000328119.6
KRT36
keratin 36
chr8_+_52730143 0.69 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr14_-_51027838 0.69 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_-_190044480 0.68 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr7_-_37026108 0.67 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chrX_+_135252050 0.67 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr15_-_22448819 0.66 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr9_+_21967137 0.65 ENST00000441769.2
C9orf53
chromosome 9 open reading frame 53
chr8_-_91095099 0.64 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr12_+_130646999 0.64 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr15_-_80263506 0.64 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr4_-_156787425 0.63 ENST00000537611.2
ASIC5
acid-sensing (proton-gated) ion channel family member 5
chr2_-_216878305 0.63 ENST00000263268.6
MREG
melanoregulin
chr7_+_141811539 0.62 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chr2_+_89986318 0.61 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr4_-_76928641 0.61 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr14_+_73706308 0.61 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr14_-_72458326 0.61 ENST00000542853.1
AC005477.1
AC005477.1
chr3_-_141747950 0.61 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chrX_+_135251783 0.59 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr19_-_54618650 0.59 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr4_-_47983519 0.58 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr13_-_46679144 0.58 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr2_-_209010874 0.58 ENST00000260988.4
CRYGB
crystallin, gamma B
chr2_-_214013353 0.57 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_152386732 0.57 ENST00000271835.3
CRNN
cornulin
chr4_+_41258786 0.56 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr10_-_96829246 0.56 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr3_+_111630451 0.56 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr7_-_80141328 0.55 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr6_-_27114577 0.55 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr12_-_30887948 0.55 ENST00000433722.2
CAPRIN2
caprin family member 2
chr3_-_185270342 0.55 ENST00000424591.2
LIPH
lipase, member H
chr1_+_73771844 0.55 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chr14_-_57272366 0.55 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chrX_+_135251835 0.55 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr13_-_46679185 0.54 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr9_-_114521783 0.54 ENST00000394779.3
ENST00000394777.4
C9orf84
chromosome 9 open reading frame 84
chr7_+_134576317 0.53 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr3_-_37216055 0.53 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr16_-_21663950 0.53 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr8_+_77318769 0.53 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr6_+_152011628 0.53 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr12_-_62586543 0.52 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr1_+_154401791 0.52 ENST00000476006.1
IL6R
interleukin 6 receptor
chr6_-_27775694 0.51 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr12_+_1800179 0.51 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr12_-_6579833 0.51 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr6_+_153071925 0.51 ENST00000367244.3
ENST00000367243.3
VIP
vasoactive intestinal peptide
chr3_-_178984759 0.50 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr2_+_33359646 0.50 ENST00000390003.4
ENST00000418533.2
LTBP1
latent transforming growth factor beta binding protein 1
chr2_+_28618532 0.49 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr19_-_54619006 0.49 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr17_-_39553844 0.49 ENST00000251645.2
KRT31
keratin 31
chr11_+_35201826 0.49 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr8_-_131399110 0.49 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr11_+_63606373 0.48 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr2_+_33359687 0.48 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr20_-_46415341 0.47 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr6_-_35109145 0.47 ENST00000373974.4
ENST00000244645.3
TCP11
t-complex 11, testis-specific
chr7_+_26591441 0.47 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2
AC004947.2
chr3_+_16306837 0.47 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr1_+_948803 0.47 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr17_-_39203519 0.47 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr4_-_100065419 0.47 ENST00000504125.1
ENST00000505590.1
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr17_+_9728828 0.47 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr14_+_57671888 0.46 ENST00000391612.1
AL391152.1
AL391152.1
chr12_-_52828147 0.45 ENST00000252245.5
KRT75
keratin 75
chr1_+_70876926 0.45 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr11_-_107729887 0.45 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr13_-_46626847 0.44 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr4_+_187148556 0.44 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr9_-_134145880 0.44 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr19_-_19626351 0.44 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr12_-_52779433 0.43 ENST00000257951.3
KRT84
keratin 84
chr12_-_71148357 0.43 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr4_-_39033963 0.43 ENST00000381938.3
TMEM156
transmembrane protein 156
chr7_+_139529040 0.43 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr11_-_125648690 0.43 ENST00000436890.2
ENST00000358524.3
PATE2
prostate and testis expressed 2
chr21_-_31864275 0.43 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr2_+_234602305 0.43 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr10_-_115904361 0.43 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr17_+_58018269 0.42 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr16_-_21663919 0.42 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr12_-_71148413 0.42 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr6_+_42584847 0.42 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr17_+_17082842 0.42 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chrX_-_18690210 0.41 ENST00000379984.3
RS1
retinoschisin 1
chr9_-_28670283 0.41 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr6_+_12007963 0.41 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr2_+_37571717 0.40 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr3_+_100328433 0.40 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr17_-_71410794 0.40 ENST00000424778.1
SDK2
sidekick cell adhesion molecule 2
chr15_-_58571445 0.40 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr11_-_3663212 0.40 ENST00000397067.3
ART5
ADP-ribosyltransferase 5
chr4_-_39979576 0.40 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr1_-_168464875 0.40 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr7_-_80551671 0.40 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_173600514 0.39 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_+_139528952 0.39 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr2_+_37571845 0.39 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr4_-_174320687 0.39 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr17_-_40575535 0.39 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr9_+_5450503 0.39 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chr2_+_29336855 0.38 ENST00000404424.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr20_-_5426332 0.38 ENST00000420529.1
LINC00658
long intergenic non-protein coding RNA 658
chr16_+_20775358 0.38 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr2_+_207024306 0.38 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr15_+_35270552 0.37 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr4_+_144354644 0.37 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr8_+_97597148 0.37 ENST00000521590.1
SDC2
syndecan 2
chr1_-_242162375 0.37 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr3_+_157827841 0.37 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1
arginine/serine-rich coiled-coil 1
chr9_+_125132803 0.37 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr18_+_45778672 0.37 ENST00000600091.1
AC091150.1
HCG1818186; Uncharacterized protein
chr14_+_56584414 0.37 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr6_+_26199737 0.36 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr3_-_99569821 0.36 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr13_+_53030107 0.36 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr13_-_47012325 0.36 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr6_-_131321863 0.36 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_-_164796269 0.36 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr1_-_167059830 0.36 ENST00000367868.3
GPA33
glycoprotein A33 (transmembrane)
chr9_-_21995249 0.35 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_+_90098606 0.35 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr18_+_11981547 0.35 ENST00000588927.1
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr17_-_55911970 0.35 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chrX_+_99899180 0.34 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr15_+_52155001 0.34 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr8_+_31497271 0.34 ENST00000520407.1
NRG1
neuregulin 1
chr3_+_149191723 0.34 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr9_+_75229616 0.34 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr4_-_69111401 0.34 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr4_+_187187098 0.34 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr10_-_90712520 0.34 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr15_-_99789736 0.34 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr9_+_116263778 0.34 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr3_-_108476231 0.34 ENST00000295755.6
RETNLB
resistin like beta
chr5_-_119740532 0.34 ENST00000569928.1
RP11-574H6.1
RP11-574H6.1
chr15_-_66797172 0.34 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4
ribosomal protein L4
chr9_+_77112244 0.33 ENST00000376896.3
RORB
RAR-related orphan receptor B
chr15_+_91411810 0.33 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chrX_-_40506766 0.33 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
CXorf38
chromosome X open reading frame 38
chr20_+_58713514 0.33 ENST00000432910.1
RP5-1043L13.1
RP5-1043L13.1
chr3_-_27498235 0.32 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr5_-_22853429 0.32 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr22_+_23248512 0.32 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr12_+_101988627 0.32 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr20_-_7921090 0.32 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chrX_+_73164167 0.32 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr17_+_54230819 0.32 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr7_-_72992865 0.32 ENST00000452475.1
TBL2
transducin (beta)-like 2
chr1_+_52682052 0.31 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.5 1.6 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 1.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3 0.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 1.7 GO:0072564 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 1.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.6 GO:0007412 axon target recognition(GO:0007412)
0.2 0.5 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.5 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.9 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 1.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.5 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.6 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.3 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.7 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.7 GO:0097338 response to clozapine(GO:0097338)
0.1 1.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.4 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.5 GO:0046098 guanine metabolic process(GO:0046098)
0.1 2.0 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.7 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.1 GO:1902908 regulation of melanosome transport(GO:1902908) regulation of melanosome organization(GO:1903056)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.9 GO:1900378 regulation of melanin biosynthetic process(GO:0048021) positive regulation of melanin biosynthetic process(GO:0048023) regulation of secondary metabolite biosynthetic process(GO:1900376) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.3 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.9 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.5 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.4 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.5 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 0.7 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.5 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.2 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.2 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.2 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 0.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.4 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 1.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 7.1 GO:0031424 keratinization(GO:0031424)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.3 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0009642 response to light intensity(GO:0009642)
0.0 0.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.4 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 1.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:1903978 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.0 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.8 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.6 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 1.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 1.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.7 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.3 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 1.9 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.6 GO:0048599 oocyte development(GO:0048599)
0.0 0.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.5 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.6 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.0 GO:0042223 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 2.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.4 1.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.7 GO:0033150 cytoskeletal calyx(GO:0033150)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 2.9 GO:0030478 actin cap(GO:0030478)
0.2 0.9 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.9 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.5 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.0 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 6.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.0 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.5 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 1.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 0.8 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 0.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 1.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 1.5 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.5 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.2 0.5 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 0.7 GO:0005503 all-trans retinal binding(GO:0005503)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 3.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.4 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.4 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.5 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 2.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550) phosphotransferase activity, phosphate group as acceptor(GO:0016776) nucleobase-containing compound kinase activity(GO:0019205)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.6 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0022853 active ion transmembrane transporter activity(GO:0022853)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 2.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 2.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN