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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HSF1

Z-value: 0.81

Motif logo

Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.6 heat shock transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg19_v2_chr8_+_145515263_145515299-0.441.5e-02Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_33041378 5.13 ENST00000428995.1
major histocompatibility complex, class II, DP alpha 1
chr20_+_31870927 4.45 ENST00000253354.1
BPI fold containing family B, member 1
chr19_-_55672037 4.29 ENST00000588076.1
dynein, axonemal, assembly factor 3
chr20_+_18794370 3.39 ENST00000377428.2
SCP2 sterol-binding domain containing 1
chr6_-_32557610 3.03 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr7_-_99573677 3.01 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr6_-_32498046 3.00 ENST00000374975.3
major histocompatibility complex, class II, DR beta 5
chr7_-_99573640 2.84 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr9_+_127615733 2.80 ENST00000373574.1
WD repeat domain 38
chr2_+_132286754 2.74 ENST00000434330.1
coiled-coil domain containing 74A
chr5_+_156696362 2.73 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr2_+_26624775 2.17 ENST00000288710.2
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr18_-_71815051 2.17 ENST00000582526.1
ENST00000419743.2
F-box protein 15
chr18_-_71814999 2.15 ENST00000269500.5
F-box protein 15
chr7_-_5821225 2.03 ENST00000416985.1
ring finger protein 216
chr6_+_32605195 1.97 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr3_+_42947600 1.92 ENST00000328199.6
ENST00000541208.1
zinc finger protein 662
chr2_-_238499303 1.90 ENST00000409576.1
RAB17, member RAS oncogene family
chr9_-_138391692 1.87 ENST00000429260.2
chromosome 9 open reading frame 116
chr2_+_85981008 1.80 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr13_-_26625169 1.75 ENST00000319420.3
shisa family member 2
chr2_+_106682103 1.72 ENST00000238044.3
chromosome 2 open reading frame 40
chr1_-_60539405 1.67 ENST00000450089.2
chromosome 1 open reading frame 87
chr2_-_27851843 1.66 ENST00000324364.3
coiled-coil domain containing 121
chr7_-_138347897 1.66 ENST00000288513.5
SVOP-like
chr1_-_60539422 1.62 ENST00000371201.3
chromosome 1 open reading frame 87
chr14_-_106926724 1.60 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr5_+_131630117 1.58 ENST00000200652.3
solute carrier family 22 (organic cation/zwitterion transporter), member 4
chr19_-_6720686 1.57 ENST00000245907.6
complement component 3
chr1_-_151345159 1.50 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
selenium binding protein 1
chr2_-_238499131 1.47 ENST00000538644.1
RAB17, member RAS oncogene family
chr4_+_55524085 1.43 ENST00000412167.2
ENST00000288135.5
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr3_-_107941230 1.34 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr12_+_111051832 1.33 ENST00000550703.2
ENST00000551590.1
tectonic family member 1
chr5_-_110062384 1.29 ENST00000429839.2
transmembrane protein 232
chr12_+_111051902 1.26 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
tectonic family member 1
chr3_+_160473996 1.21 ENST00000498165.1
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr22_-_36556821 1.20 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
apolipoprotein L, 3
chr6_+_32605134 1.19 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr10_+_114133773 1.19 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr4_-_84030996 1.15 ENST00000411416.2
placenta-specific 8
chr3_-_46506358 1.14 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr5_-_110062349 1.13 ENST00000511883.2
ENST00000455884.2
transmembrane protein 232
chr21_-_43735446 1.13 ENST00000398431.2
trefoil factor 3 (intestinal)
chr4_+_106816644 1.09 ENST00000506666.1
ENST00000503451.1
nephronectin
chr15_-_72490114 1.08 ENST00000309731.7
GRAM domain containing 2
chr4_+_76932326 1.07 ENST00000513353.1
ENST00000341029.5
ADP-ribosyltransferase 3
chrX_-_73072534 1.01 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr5_-_101632153 1.00 ENST00000310954.6
solute carrier organic anion transporter family, member 4C1
chr2_-_202316260 1.00 ENST00000332624.3
trafficking protein, kinesin binding 2
chr7_+_100728720 0.99 ENST00000306085.6
ENST00000412507.1
tripartite motif containing 56
chr1_+_212782012 0.99 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr12_+_93772326 0.98 ENST00000550056.1
ENST00000549992.1
ENST00000548662.1
ENST00000547014.1
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr2_+_109403193 0.96 ENST00000412964.2
ENST00000295124.4
coiled-coil domain containing 138
chr1_+_47489240 0.92 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr10_-_116444371 0.92 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr3_-_46506563 0.91 ENST00000231751.4
lactotransferrin
chr1_-_173638976 0.90 ENST00000333279.2
ankyrin repeat domain 45
chr2_+_102624977 0.88 ENST00000441002.1
interleukin 1 receptor, type II
chr2_+_241564655 0.87 ENST00000407714.1
G protein-coupled receptor 35
chr6_+_32811861 0.87 ENST00000453426.1
TAP1 and PSMB8 antisense RNA 1
chr1_-_114302086 0.85 ENST00000369604.1
ENST00000357783.2
putative homeodomain transcription factor 1
chr16_-_18468926 0.84 ENST00000545114.1
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr6_-_52705641 0.82 ENST00000370989.2
glutathione S-transferase alpha 5
chr7_-_6010263 0.82 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
radial spoke head 10 homolog B (Chlamydomonas)
chr9_+_33025209 0.81 ENST00000330899.4
ENST00000544625.1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr19_-_4559814 0.81 ENST00000586582.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr6_-_46620522 0.81 ENST00000275016.2
cytochrome P450, family 39, subfamily A, polypeptide 1
chr7_+_6793740 0.79 ENST00000403107.1
ENST00000404077.1
ENST00000435395.1
ENST00000418406.1
radial spoke head 10 homolog B2 (Chlamydomonas)
chr10_+_63422695 0.78 ENST00000330194.2
ENST00000389639.3
chromosome 10 open reading frame 107
chr3_-_187454281 0.77 ENST00000232014.4
B-cell CLL/lymphoma 6
chr9_-_88715044 0.76 ENST00000388711.3
ENST00000466178.1
golgi membrane protein 1
chr21_+_45148735 0.76 ENST00000327574.4
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_+_212738676 0.75 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr6_+_32811885 0.75 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr9_+_74764340 0.74 ENST00000376986.1
ENST00000358399.3
guanine deaminase
chr9_-_34372830 0.74 ENST00000379142.3
KIAA1161
chrX_+_49020121 0.74 ENST00000415364.1
ENST00000376338.3
ENST00000425285.1
MAGI family member, X-linked
chr2_+_27274506 0.74 ENST00000451003.1
ENST00000323064.8
ENST00000360131.4
ATP/GTP binding protein-like 5
chr18_+_44526786 0.73 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chr12_+_119772502 0.73 ENST00000536742.1
ENST00000327554.2
coiled-coil domain containing 60
chr11_+_10471836 0.73 ENST00000444303.2
adenosine monophosphate deaminase 3
chrX_+_49020882 0.71 ENST00000454342.1
MAGI family member, X-linked
chr20_-_44455976 0.71 ENST00000372555.3
troponin C type 2 (fast)
chr1_+_152635854 0.70 ENST00000368784.1
late cornified envelope 2D
chr19_-_7766991 0.70 ENST00000597921.1
ENST00000346664.5
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr7_-_102715263 0.70 ENST00000379305.3
F-box and leucine-rich repeat protein 13
chr11_-_89956227 0.69 ENST00000457199.2
ENST00000530765.1
cysteine and histidine-rich domain (CHORD) containing 1
chr19_+_47813110 0.68 ENST00000355085.3
complement component 5a receptor 1
chr3_+_93698974 0.67 ENST00000535334.1
ENST00000478400.1
ENST00000303097.7
ENST00000394222.3
ENST00000471138.1
ENST00000539730.1
ADP-ribosylation factor-like 13B
chr7_+_107301065 0.67 ENST00000265715.3
solute carrier family 26 (anion exchanger), member 4
chr11_-_26593677 0.67 ENST00000527569.1
mucin 15, cell surface associated
chrX_-_112084043 0.66 ENST00000304758.1
angiomotin
chr3_+_119421849 0.66 ENST00000273390.5
ENST00000463700.1
MYCBP-associated, testis expressed 1
chr1_+_15256230 0.66 ENST00000376028.4
ENST00000400798.2
kazrin, periplakin interacting protein
chr14_+_75988768 0.66 ENST00000286639.6
basic leucine zipper transcription factor, ATF-like
chr1_+_202830876 0.65 ENST00000456105.2
RP11-480I12.7
chr22_-_29196546 0.64 ENST00000403532.3
ENST00000216037.6
X-box binding protein 1
chr19_-_50311896 0.64 ENST00000529634.2
fuzzy planar cell polarity protein
chr6_-_52926539 0.64 ENST00000350082.5
ENST00000356971.3
intestinal cell (MAK-like) kinase
chrX_-_7895755 0.64 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr4_-_25865159 0.64 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_-_101321584 0.63 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr12_-_76742183 0.63 ENST00000393262.3
Bardet-Biedl syndrome 10
chr2_+_190722119 0.62 ENST00000452382.1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr11_-_105892937 0.61 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr10_-_13544945 0.60 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr9_-_100395756 0.60 ENST00000341170.4
ENST00000354801.2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr17_+_7608511 0.60 ENST00000226091.2
ephrin-B3
chr2_+_85766280 0.60 ENST00000306434.3
methionine adenosyltransferase II, alpha
chr19_+_42806250 0.60 ENST00000598490.1
ENST00000341747.3
proline rich 19
chr3_+_56591184 0.59 ENST00000422222.1
ENST00000394672.3
ENST00000326595.7
coiled-coil domain containing 66
chr10_+_15001430 0.59 ENST00000407572.1
meiosis/spermiogenesis associated 1
chr17_+_7590734 0.59 ENST00000457584.2
WD repeat containing, antisense to TP53
chr11_+_77184416 0.59 ENST00000598970.1
DKFZP434E1119
chr11_-_89956461 0.59 ENST00000320585.6
cysteine and histidine-rich domain (CHORD) containing 1
chrX_-_48776292 0.58 ENST00000376509.4
pim-2 oncogene
chr9_-_86432547 0.58 ENST00000376365.3
ENST00000376371.2
G kinase anchoring protein 1
chr6_+_29910301 0.57 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr17_+_72427477 0.56 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr9_-_97356075 0.55 ENST00000375337.3
fructose-1,6-bisphosphatase 2
chr15_-_42186248 0.53 ENST00000320955.6
spectrin, beta, non-erythrocytic 5
chr11_+_123986069 0.53 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
von Willebrand factor A domain containing 5A
chr2_+_233527443 0.53 ENST00000410095.1
EF-hand domain family, member D1
chr11_-_86383650 0.52 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr22_+_35776828 0.52 ENST00000216117.8
heme oxygenase (decycling) 1
chr19_+_3762645 0.52 ENST00000330133.4
mitochondrial ribosomal protein L54
chr2_+_217524323 0.52 ENST00000456764.1
insulin-like growth factor binding protein 2, 36kDa
chr10_-_62332357 0.51 ENST00000503366.1
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_101443476 0.51 ENST00000327230.4
ENST00000494050.1
centrosomal protein 97kDa
chr2_+_103089756 0.50 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr21_-_43346790 0.50 ENST00000329623.7
C2 calcium-dependent domain containing 2
chr1_+_166958497 0.49 ENST00000367870.2
maelstrom spermatogenic transposon silencer
chr6_-_131949200 0.49 ENST00000539158.1
ENST00000368058.1
mediator complex subunit 23
chr7_+_150065278 0.49 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr1_+_156117149 0.48 ENST00000435124.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr9_-_139922726 0.48 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr15_-_82338460 0.48 ENST00000558133.1
ENST00000329713.4
mex-3 RNA binding family member B
chr9_-_116102562 0.48 ENST00000374193.4
ENST00000465979.1
WD repeat domain 31
chr17_+_72426891 0.48 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr2_+_219247021 0.48 ENST00000539932.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr12_+_6898638 0.47 ENST00000011653.4
CD4 molecule
chr17_-_3595181 0.47 ENST00000552050.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr3_-_39234074 0.47 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
xin actin-binding repeat containing 1
chr1_-_27682962 0.47 ENST00000486046.1
mitogen-activated protein kinase kinase kinase 6
chr21_+_42733870 0.47 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
myxovirus (influenza virus) resistance 2 (mouse)
chr8_-_56685859 0.46 ENST00000523423.1
ENST00000523073.1
ENST00000519784.1
ENST00000434581.2
ENST00000519780.1
ENST00000521229.1
ENST00000522576.1
ENST00000523180.1
ENST00000522090.1
transmembrane protein 68
chr19_-_2740036 0.46 ENST00000586572.1
ENST00000269740.4
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr6_-_39282329 0.45 ENST00000373231.4
potassium channel, subfamily K, member 17
chr17_+_76227391 0.45 ENST00000586400.1
ENST00000421688.1
ENST00000374946.3
transmembrane protein 235
chr12_-_55042140 0.45 ENST00000293371.6
ENST00000456047.2
dermcidin
chr14_+_22694606 0.45 ENST00000390463.3
T cell receptor alpha variable 36/delta variable 7
chr14_-_21493123 0.45 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr1_+_28261492 0.44 ENST00000373894.3
sphingomyelin phosphodiesterase, acid-like 3B
chr3_-_183735651 0.44 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr4_-_48136217 0.43 ENST00000264316.4
TXK tyrosine kinase
chr17_+_73996987 0.43 ENST00000588812.1
ENST00000448471.1
cyclin-dependent kinase 3
chr2_-_96701722 0.43 ENST00000434632.1
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr4_-_48082192 0.43 ENST00000507351.1
TXK tyrosine kinase
chr3_-_52931557 0.43 ENST00000504329.1
ENST00000355083.5
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr11_+_60050026 0.43 ENST00000395016.3
membrane-spanning 4-domains, subfamily A, member 4A
chr1_+_15632231 0.42 ENST00000375997.4
ENST00000524761.1
ENST00000375995.3
ENST00000401090.2
forkhead-associated (FHA) phosphopeptide binding domain 1
chr12_+_93772402 0.42 ENST00000546925.1
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr1_+_28261621 0.42 ENST00000549094.1
sphingomyelin phosphodiesterase, acid-like 3B
chr9_-_116102530 0.42 ENST00000374195.3
ENST00000341761.4
WD repeat domain 31
chr22_-_17680472 0.42 ENST00000330232.4
cat eye syndrome chromosome region, candidate 1
chr19_+_50338234 0.41 ENST00000593767.1
mediator complex subunit 25
chr8_-_38386175 0.41 ENST00000437935.2
ENST00000358138.1
chromosome 8 open reading frame 86
chr11_-_107328527 0.40 ENST00000282251.5
ENST00000433523.1
CWF19-like 2, cell cycle control (S. pombe)
chr5_+_178450753 0.40 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
zinc finger protein 879
chr2_-_218867711 0.40 ENST00000446903.1
tensin 1
chr19_+_37342547 0.40 ENST00000331800.4
ENST00000586646.1
zinc finger protein 345
chr17_+_53342311 0.39 ENST00000226067.5
hepatic leukemia factor
chr19_-_47922750 0.39 ENST00000331559.5
Meis homeobox 3
chr7_+_5919458 0.39 ENST00000416608.1
oncomodulin
chr20_-_23669590 0.39 ENST00000217423.3
cystatin S
chr5_+_122110691 0.38 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chrX_+_108779870 0.38 ENST00000372107.1
nuclear transport factor 2-like export factor 2
chr6_-_116575226 0.38 ENST00000420283.1
TSPY-like 4
chr9_-_88714421 0.38 ENST00000388712.3
golgi membrane protein 1
chr1_-_10856694 0.37 ENST00000377022.3
ENST00000344008.5
castor zinc finger 1
chr19_+_3762703 0.37 ENST00000589174.1
mitochondrial ribosomal protein L54
chr4_-_104021009 0.37 ENST00000509245.1
ENST00000296424.4
3-hydroxybutyrate dehydrogenase, type 2
chr20_-_23807358 0.37 ENST00000304725.2
cystatin SA
chr6_-_131949305 0.36 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
mediator complex subunit 23
chrX_+_130192216 0.36 ENST00000276211.5
Rho GTPase activating protein 36
chr16_-_88770019 0.36 ENST00000541206.2
ring finger protein 166
chr17_+_4634705 0.36 ENST00000575284.1
ENST00000573708.1
ENST00000293777.5
mediator complex subunit 11
chr3_-_125775629 0.36 ENST00000383598.2
solute carrier family 41, member 3
chr17_+_71228793 0.36 ENST00000426147.2
chromosome 17 open reading frame 80
chr17_-_34313685 0.35 ENST00000435911.2
ENST00000586216.1
ENST00000394509.4
chemokine (C-C motif) ligand 14
chr13_+_50571155 0.35 ENST00000420995.2
ENST00000378182.3
ENST00000356017.4
ENST00000457662.2
tripartite motif containing 13
chr1_-_224517823 0.35 ENST00000469968.1
ENST00000436927.1
ENST00000469075.1
ENST00000488718.1
ENST00000482491.1
ENST00000340871.4
ENST00000492281.1
ENST00000361463.3
ENST00000391875.2
ENST00000461546.1
nuclear VCP-like
chr6_+_31795506 0.34 ENST00000375650.3
heat shock 70kDa protein 1B
chr18_+_13611763 0.34 ENST00000585931.1
low density lipoprotein receptor class A domain containing 4
chrX_-_67653614 0.34 ENST00000355520.5
oligophrenin 1
chr10_+_103348031 0.34 ENST00000370151.4
ENST00000370147.1
ENST00000370148.2
deleted in primary ciliary dyskinesia homolog (mouse)
chr10_-_53459319 0.34 ENST00000331173.4
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr1_-_156918806 0.34 ENST00000315174.8
Rho guanine nucleotide exchange factor (GEF) 11
chr12_+_51632638 0.34 ENST00000549732.2
DAZ associated protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 1.4 GO:0070662 mast cell proliferation(GO:0070662)
0.7 2.0 GO:0033212 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.7 3.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.6 3.0 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.6 1.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.6 4.4 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.5 1.6 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.4 1.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.4 1.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 2.6 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.3 1.0 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 2.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.1 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.3 0.8 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 1.4 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.7 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.2 0.9 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 0.6 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.2 1.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 0.8 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 0.6 GO:0032203 telomere formation via telomerase(GO:0032203)
0.2 0.8 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 5.9 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 6.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 0.6 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 0.5 GO:0070839 divalent metal ion export(GO:0070839)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.9 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.9 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.3 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.3 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.5 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.1 0.7 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.2 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 0.3 GO:0071529 cementum mineralization(GO:0071529)
0.1 1.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.4 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 1.7 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.2 GO:0051168 nuclear export(GO:0051168)
0.1 0.5 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 0.3 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.9 GO:0015705 iodide transport(GO:0015705)
0.1 11.7 GO:0031295 T cell costimulation(GO:0031295)
0.1 2.2 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.3 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.3 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.5 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 1.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.7 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 0.2 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.7 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.8 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 1.6 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 0.3 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.5 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:0043335 protein unfolding(GO:0043335)
0.1 0.5 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 0.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 1.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.2 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0021678 third ventricle development(GO:0021678)
0.0 0.5 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.4 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 3.1 GO:0032608 interferon-beta production(GO:0032608)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0072525 pyridine-containing compound biosynthetic process(GO:0072525)
0.0 0.1 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.0 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.7 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.1 GO:1901142 insulin metabolic process(GO:1901142)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.2 GO:0051085 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 2.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.3 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.6 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0046668 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.5 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0042138 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0060021 palate development(GO:0060021)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.6 GO:0007140 male meiosis(GO:0007140)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.0 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 4.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.5 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 14.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 1.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 1.8 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.2 0.7 GO:0001534 radial spoke(GO:0001534)
0.2 1.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 0.5 GO:0030849 autosome(GO:0030849)
0.1 1.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 2.6 GO:0036038 MKS complex(GO:0036038)
0.1 1.3 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.7 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 0.6 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.9 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 1.6 GO:0042629 mast cell granule(GO:0042629)
0.0 3.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.9 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 2.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0000793 condensed chromosome kinetochore(GO:0000777) condensed chromosome, centromeric region(GO:0000779) condensed chromosome(GO:0000793)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 1.6 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.3 5.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.3 0.8 GO:0031403 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.2 1.4 GO:0052843 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 0.7 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.2 6.6 GO:0042605 peptide antigen binding(GO:0042605)
0.2 0.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.9 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.5 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.2 1.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 1.5 GO:0008430 selenium binding(GO:0008430)
0.1 0.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.8 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.8 GO:0019863 IgE binding(GO:0019863)
0.1 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036) dynactin binding(GO:0034452)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 1.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 1.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0042623 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled(GO:0042623) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.8 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.9 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins