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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for HSF4

Z-value: 0.58

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Transcription factors associated with HSF4

Gene Symbol Gene ID Gene Info
HSF4
ENSG00000102878.11 heat shock transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF4hg19_v2_chr16_+_67198683_671987150.202.9e-01Click!

Activity profile of HSF4 motif

Sorted Z-values of HSF4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_74137374 3.26 ENST00000322957.6
FOXJ1
forkhead box J1
chr18_-_71815051 2.65 ENST00000582526.1
ENST00000419743.2
FBXO15
F-box protein 15
chr18_-_71814999 2.64 ENST00000269500.5
FBXO15
F-box protein 15
chr19_-_55672037 2.48 ENST00000588076.1
DNAAF3
dynein, axonemal, assembly factor 3
chr1_-_60539405 1.93 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr1_-_60539422 1.91 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr1_-_173638976 1.42 ENST00000333279.2
ANKRD45
ankyrin repeat domain 45
chr2_-_238499303 1.40 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr5_+_140602904 1.21 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr20_+_18794370 1.20 ENST00000377428.2
SCP2D1
SCP2 sterol-binding domain containing 1
chr5_-_13944652 1.13 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr1_-_26633067 1.11 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11
UBX domain protein 11
chr7_-_56119156 1.10 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr11_-_122932730 1.09 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr7_-_56118981 1.04 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH
phosphoserine phosphatase
chr11_-_122933043 1.00 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8
heat shock 70kDa protein 8
chr13_-_31736027 0.99 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr9_+_33025209 0.99 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr19_-_6720686 0.98 ENST00000245907.6
C3
complement component 3
chr11_-_89956461 0.97 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr19_+_859654 0.94 ENST00000592860.1
CFD
complement factor D (adipsin)
chr11_-_89956227 0.93 ENST00000457199.2
ENST00000530765.1
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr1_+_27248203 0.93 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr13_-_31736132 0.89 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr7_-_56119238 0.87 ENST00000275605.3
ENST00000395471.3
PSPH
phosphoserine phosphatase
chr10_-_62332357 0.86 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr16_-_18468926 0.80 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr1_+_212782012 0.79 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr3_+_101443476 0.77 ENST00000327230.4
ENST00000494050.1
CEP97
centrosomal protein 97kDa
chr11_-_108408895 0.76 ENST00000443411.1
ENST00000533052.1
EXPH5
exophilin 5
chr10_+_131265443 0.73 ENST00000306010.7
MGMT
O-6-methylguanine-DNA methyltransferase
chr4_+_76932326 0.71 ENST00000513353.1
ENST00000341029.5
ART3
ADP-ribosyltransferase 3
chr2_-_238499131 0.71 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr14_-_102553371 0.70 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr9_+_74764340 0.67 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr19_-_51893827 0.65 ENST00000574814.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr13_-_31736478 0.62 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr9_+_74764278 0.60 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr8_+_37594185 0.60 ENST00000518586.1
ENST00000335171.6
ENST00000521644.1
ERLIN2
ER lipid raft associated 2
chr4_-_25865159 0.60 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_+_33474826 0.59 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr17_+_33474860 0.59 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr19_+_859425 0.56 ENST00000327726.6
CFD
complement factor D (adipsin)
chr15_+_41952591 0.53 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr14_-_61124977 0.52 ENST00000554986.1
SIX1
SIX homeobox 1
chr5_-_70272055 0.47 ENST00000514857.2
NAIP
NLR family, apoptosis inhibitory protein
chr5_+_140501581 0.46 ENST00000194152.1
PCDHB4
protocadherin beta 4
chr1_+_44679159 0.45 ENST00000315913.5
ENST00000372289.2
DMAP1
DNA methyltransferase 1 associated protein 1
chr1_+_44679113 0.44 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1
DNA methyltransferase 1 associated protein 1
chr2_+_85766280 0.44 ENST00000306434.3
MAT2A
methionine adenosyltransferase II, alpha
chr19_+_6135646 0.44 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr11_+_112046190 0.43 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr5_-_140053152 0.43 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr16_-_28937027 0.43 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr5_-_10249990 0.40 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chr18_+_9136758 0.39 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr7_-_100493744 0.38 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr5_+_56469843 0.38 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr9_-_88715044 0.37 ENST00000388711.3
ENST00000466178.1
GOLM1
golgi membrane protein 1
chr6_+_44215603 0.37 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr21_+_44394620 0.36 ENST00000291547.5
PKNOX1
PBX/knotted 1 homeobox 1
chr9_-_88714421 0.36 ENST00000388712.3
GOLM1
golgi membrane protein 1
chr16_+_14844670 0.35 ENST00000553201.1
NPIPA2
nuclear pore complex interacting protein family, member A2
chr19_-_52133588 0.34 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr20_-_43589109 0.33 ENST00000372813.3
TOMM34
translocase of outer mitochondrial membrane 34
chr15_+_96869165 0.33 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_-_27472198 0.31 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU
clusterin
chr4_-_159644507 0.31 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr6_+_29910301 0.30 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr18_-_19284724 0.30 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr5_+_56469775 0.30 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr1_+_154966058 0.30 ENST00000392487.1
LENEP
lens epithelial protein
chrX_-_102942961 0.29 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2
mortality factor 4 like 2
chr16_-_68034470 0.29 ENST00000412757.2
DPEP2
dipeptidase 2
chr17_+_73996987 0.29 ENST00000588812.1
ENST00000448471.1
CDK3
cyclin-dependent kinase 3
chr16_-_23568651 0.28 ENST00000563232.1
ENST00000563459.1
ENST00000449606.1
EARS2
glutamyl-tRNA synthetase 2, mitochondrial
chr15_+_44092784 0.28 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr13_-_31191642 0.27 ENST00000405805.1
HMGB1
high mobility group box 1
chr2_-_69180012 0.27 ENST00000481498.1
GKN2
gastrokine 2
chr5_+_133706865 0.27 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr22_+_29168652 0.27 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr9_-_13279406 0.26 ENST00000546205.1
MPDZ
multiple PDZ domain protein
chr11_+_193065 0.26 ENST00000342878.2
SCGB1C1
secretoglobin, family 1C, member 1
chr2_+_198365095 0.26 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr16_+_76587314 0.26 ENST00000563764.1
RP11-58C22.1
Uncharacterized protein
chrX_+_108780062 0.26 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr11_+_65266507 0.25 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr5_-_133706695 0.25 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr22_+_29664248 0.25 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWSR1
EWS RNA-binding protein 1
chr22_-_24181174 0.24 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr18_+_57567180 0.24 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr8_-_37594944 0.24 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chrX_-_102943022 0.23 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr12_+_49121213 0.23 ENST00000548380.1
LINC00935
long intergenic non-protein coding RNA 935
chrX_-_39923656 0.22 ENST00000413905.1
BCOR
BCL6 corepressor
chr20_+_19867150 0.22 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chrX_+_108779870 0.21 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr2_-_69180083 0.21 ENST00000328895.4
GKN2
gastrokine 2
chr2_-_68479614 0.21 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr4_-_6383594 0.21 ENST00000335585.5
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr3_+_130612803 0.20 ENST00000510168.1
ENST00000508532.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr13_-_41593425 0.20 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chrX_-_55515635 0.20 ENST00000500968.3
USP51
ubiquitin specific peptidase 51
chr1_-_53704157 0.19 ENST00000371466.4
ENST00000371470.3
MAGOH
mago-nashi homolog, proliferation-associated (Drosophila)
chr17_-_61850894 0.19 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr11_-_1587166 0.19 ENST00000331588.4
DUSP8
dual specificity phosphatase 8
chr6_-_76782371 0.19 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr16_-_8955570 0.19 ENST00000567554.1
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr22_+_17082732 0.18 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr20_+_36149602 0.18 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr2_+_203130439 0.18 ENST00000264279.5
NOP58
NOP58 ribonucleoprotein
chr11_-_111781554 0.18 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr2_+_198365122 0.17 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr16_-_8955601 0.17 ENST00000569398.1
ENST00000568968.1
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr19_+_50354462 0.17 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chrX_-_154563889 0.17 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr11_-_62457371 0.17 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr8_+_37594130 0.17 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2
ER lipid raft associated 2
chr19_+_2269485 0.17 ENST00000582888.4
ENST00000602676.2
ENST00000322297.4
ENST00000583542.4
OAZ1
ornithine decarboxylase antizyme 1
chr15_+_79165222 0.17 ENST00000559930.1
MORF4L1
mortality factor 4 like 1
chr16_+_28875126 0.16 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr22_+_41253080 0.16 ENST00000541156.1
ENST00000414396.1
ENST00000357137.4
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr11_+_65770227 0.16 ENST00000527348.1
BANF1
barrier to autointegration factor 1
chr15_-_86338100 0.16 ENST00000536947.1
KLHL25
kelch-like family member 25
chr11_-_47869865 0.15 ENST00000530326.1
ENST00000532747.1
NUP160
nucleoporin 160kDa
chr15_+_79165112 0.15 ENST00000426013.2
MORF4L1
mortality factor 4 like 1
chr14_-_23388338 0.15 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23
RNA binding motif protein 23
chr19_+_50354393 0.15 ENST00000391842.1
PTOV1
prostate tumor overexpressed 1
chr15_+_79165151 0.15 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr19_+_50354430 0.15 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr19_-_49565254 0.15 ENST00000593537.1
NTF4
neurotrophin 4
chr18_+_13611763 0.15 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr21_-_40720974 0.13 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr11_-_47870019 0.13 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr17_+_78194205 0.13 ENST00000573809.1
ENST00000361193.3
ENST00000574967.1
ENST00000576126.1
ENST00000411502.3
ENST00000546047.2
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr1_+_196743912 0.13 ENST00000367425.4
CFHR3
complement factor H-related 3
chr11_+_65769946 0.13 ENST00000533166.1
BANF1
barrier to autointegration factor 1
chr17_-_54911250 0.13 ENST00000575658.1
ENST00000397861.2
C17orf67
chromosome 17 open reading frame 67
chr5_+_56469939 0.12 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr20_-_23669590 0.12 ENST00000217423.3
CST4
cystatin S
chr14_-_23540747 0.12 ENST00000555566.1
ENST00000338631.6
ENST00000557515.1
ENST00000397341.3
ACIN1
apoptotic chromatin condensation inducer 1
chr12_-_9885888 0.12 ENST00000327839.3
CLECL1
C-type lectin-like 1
chr19_+_782755 0.11 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr1_-_156252590 0.11 ENST00000361813.5
ENST00000368267.5
SMG5
SMG5 nonsense mediated mRNA decay factor
chr8_+_140943416 0.11 ENST00000507535.3
C8orf17
chromosome 8 open reading frame 17
chrX_+_150345054 0.10 ENST00000218316.3
GPR50
G protein-coupled receptor 50
chr11_+_20385666 0.10 ENST00000532081.1
ENST00000531058.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr11_+_65769550 0.10 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1
barrier to autointegration factor 1
chr1_+_196857144 0.09 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chrX_-_107225600 0.09 ENST00000302917.1
TEX13B
testis expressed 13B
chr12_+_65563329 0.09 ENST00000308330.2
LEMD3
LEM domain containing 3
chr19_+_751122 0.09 ENST00000215582.6
MISP
mitotic spindle positioning
chr21_+_45148735 0.09 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr21_-_40720995 0.09 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr5_+_118690466 0.09 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr16_+_68119764 0.08 ENST00000570212.1
ENST00000562926.1
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_-_69664586 0.08 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr1_-_99470368 0.08 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr14_+_63671105 0.08 ENST00000316754.3
RHOJ
ras homolog family member J
chr2_-_97405775 0.08 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr15_-_86338134 0.08 ENST00000337975.5
KLHL25
kelch-like family member 25
chr3_+_39509163 0.08 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr3_+_186501336 0.08 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2
eukaryotic translation initiation factor 4A2
chrX_+_15767971 0.07 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr22_+_29664305 0.07 ENST00000414183.2
ENST00000333395.6
ENST00000455726.1
ENST00000332035.6
EWSR1
EWS RNA-binding protein 1
chr19_-_49567124 0.07 ENST00000301411.3
NTF4
neurotrophin 4
chr2_-_208989225 0.07 ENST00000264376.4
CRYGD
crystallin, gamma D
chr1_+_156308245 0.07 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr21_+_44394742 0.07 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr14_-_68141535 0.07 ENST00000554659.1
VTI1B
vesicle transport through interaction with t-SNAREs 1B
chr16_+_29789561 0.06 ENST00000400752.4
ZG16
zymogen granule protein 16
chr11_+_63953691 0.06 ENST00000543847.1
STIP1
stress-induced-phosphoprotein 1
chr11_+_63953587 0.06 ENST00000305218.4
ENST00000538945.1
STIP1
stress-induced-phosphoprotein 1
chrX_-_152989798 0.06 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr8_-_120605194 0.06 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_+_123095155 0.06 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr8_-_57359131 0.06 ENST00000518974.1
ENST00000523051.1
ENST00000518770.1
ENST00000451791.2
PENK
proenkephalin
chr5_+_133707252 0.05 ENST00000506787.1
ENST00000507277.1
UBE2B
ubiquitin-conjugating enzyme E2B
chr17_+_34087888 0.05 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
C17orf50
chromosome 17 open reading frame 50
chr7_+_56119323 0.05 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
CCT6A
chaperonin containing TCP1, subunit 6A (zeta 1)
chr2_-_27362263 0.05 ENST00000432962.1
ENST00000335524.3
C2orf53
chromosome 2 open reading frame 53
chr11_-_10590238 0.05 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr5_+_446253 0.05 ENST00000315013.5
EXOC3
exocyst complex component 3
chr19_+_41509851 0.04 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr1_+_156308403 0.04 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr11_-_10590118 0.04 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr13_+_31191920 0.04 ENST00000255304.4
USPL1
ubiquitin specific peptidase like 1
chr7_-_26240357 0.03 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr19_-_42721819 0.03 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2
death effector domain containing 2
chr20_+_5451845 0.03 ENST00000430097.2
RP5-828H9.1
RP5-828H9.1
chr6_-_127837739 0.02 ENST00000368268.2
SOGA3
SOGA family member 3
chr8_+_143916217 0.02 ENST00000220940.1
GML
glycosylphosphatidylinositol anchored molecule like
chr7_+_5919458 0.02 ENST00000416608.1
OCM
oncomodulin
chr11_-_47870091 0.02 ENST00000526870.1
NUP160
nucleoporin 160kDa
chr1_-_182369751 0.02 ENST00000367565.1
TEDDM1
transmembrane epididymal protein 1
chr4_-_22517620 0.02 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr20_-_23731569 0.01 ENST00000304749.2
CST1
cystatin SN
chr6_-_106773291 0.01 ENST00000343245.3
ATG5
autophagy related 5
chr11_+_20385231 0.01 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr11_-_134123142 0.01 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.6 1.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 2.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 2.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.3 1.0 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.3 3.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.3 0.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.3 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 3.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.9 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.7 GO:0043335 protein unfolding(GO:0043335)
0.1 0.4 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.5 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.8 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 3.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.3 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.1 0.4 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.3 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.1 1.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.7 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.3 GO:0034486 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.0 0.8 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 5.1 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.3 0.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.9 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 2.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 5.0 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 3.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 2.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.3 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.7 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 3.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.3 GO:0019239 deaminase activity(GO:0019239)
0.0 2.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 3.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC