ISMARA results: IRF2_STAT2_IRF8

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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRF2_STAT2_IRF8_IRF1

Z-value: 2.40

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Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Gene Symbol	Gene ID	Gene Info
IRF2 Ensembl NCBI GeneCards UniProt	ENSG00000168310.6	interferon regulatory factor 2
STAT2 Ensembl NCBI GeneCards UniProt	ENSG00000170581.9	signal transducer and activator of transcription 2
IRF8 Ensembl NCBI GeneCards UniProt	ENSG00000140968.6	interferon regulatory factor 8
IRF1 Ensembl NCBI GeneCards UniProt	ENSG00000125347.9	interferon regulatory factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IRF1	hg19_v2_chr5_-_131826457_131826514	0.88	2.2e-10	Click!
STAT2	hg19_v2_chr12_-_56753858_56753930	0.53	2.4e-03	Click!
IRF8	hg19_v2_chr16_+_85942594_85942635	0.14	4.7e-01	Click!
IRF2	hg19_v2_chr4_-_185395672_185395734	0.12	5.3e-01	Click!

Activity profile of IRF2_STAT2_IRF8_IRF1 motif

Sorted Z-values of IRF2_STAT2_IRF8_IRF1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_39770803 Show fit	23.15	ENST00000518237.1	IDO1 Ensembl NCBI GeneCards UniProt Show fit	indoleamine 2,3-dioxygenase 1
chr6_+_32821924 Show fit	15.95	ENST00000374859.2 ENST00000453265.2	PSMB9 Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, beta type, 9
chr1_-_207119738 Show fit	15.18	ENST00000356495.4	PIGR Ensembl NCBI GeneCards UniProt Show fit	polymeric immunoglobulin receptor
chr2_-_7005785 Show fit	15.17	ENST00000256722.5 ENST00000404168.1 ENST00000458098.1	CMPK2 Ensembl NCBI GeneCards UniProt Show fit	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr21_+_42733870 Show fit	12.53	ENST00000330714.3 ENST00000436410.1 ENST00000435611.1	MX2 Ensembl NCBI GeneCards UniProt Show fit	myxovirus (influenza virus) resistance 2 (mouse)
chr6_-_29527702 Show fit	12.00	ENST00000377050.4	UBD Ensembl NCBI GeneCards UniProt Show fit	ubiquitin D
chr1_+_79115503 Show fit	11.81	ENST00000370747.4 ENST00000438486.1 ENST00000545124.1	IFI44 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein 44
chr1_+_79086088 Show fit	11.02	ENST00000370751.5 ENST00000342282.3	IFI44L Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein 44-like
chr9_-_32526184 Show fit	10.97	ENST00000545044.1 ENST00000379868.1	DDX58 Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr10_+_91152303 Show fit	10.56	ENST00000371804.3	IFIT1 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 1
chr4_-_169239921 Show fit	10.25	ENST00000514995.1 ENST00000393743.3	DDX60 Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr19_-_17516449 Show fit	10.05	ENST00000252593.6	BST2 Ensembl NCBI GeneCards UniProt Show fit	bone marrow stromal cell antigen 2
chr1_-_27998689 Show fit	9.84	ENST00000339145.4 ENST00000362020.4 ENST00000361157.6	IFI6 Ensembl NCBI GeneCards UniProt Show fit	interferon, alpha-inducible protein 6
chr17_+_6659153 Show fit	8.69	ENST00000441631.1 ENST00000438512.1 ENST00000346752.4 ENST00000361842.3	XAF1 Ensembl NCBI GeneCards UniProt Show fit	XIAP associated factor 1
chr1_+_948803 Show fit	8.56	ENST00000379389.4	ISG15 Ensembl NCBI GeneCards UniProt Show fit	ISG15 ubiquitin-like modifier
chr9_-_32526299 Show fit	8.49	ENST00000379882.1 ENST00000379883.2	DDX58 Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr10_+_91087651 Show fit	8.24	ENST00000371818.4	IFIT3 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 3
chr10_+_91092241 Show fit	7.61	ENST00000371811.4	IFIT3 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 3
chr3_+_187086120 Show fit	7.09	ENST00000259030.2	RTP4 Ensembl NCBI GeneCards UniProt Show fit	receptor (chemosensory) transporter protein 4
chr17_+_4643337 Show fit	6.82	ENST00000592813.1	ZMYND15 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, MYND-type containing 15
chr7_-_122526799 Show fit	6.67	ENST00000334010.7 ENST00000313070.7	CADPS2 Ensembl NCBI GeneCards UniProt Show fit	Ca++-dependent secretion activator 2
chr2_+_7017796 Show fit	6.17	ENST00000382040.3	RSAD2 Ensembl NCBI GeneCards UniProt Show fit	radical S-adenosyl methionine domain containing 2
chr17_+_4643300 Show fit	6.16	ENST00000433935.1	ZMYND15 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, MYND-type containing 15
chr20_-_25038804 Show fit	6.12	ENST00000323482.4	ACSS1 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase short-chain family member 1
chr12_+_6561190 Show fit	6.02	ENST00000544021.1 ENST00000266556.7	TAPBPL Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein-like
chr21_+_42792442 Show fit	5.69	ENST00000398600.2	MX1 Ensembl NCBI GeneCards UniProt Show fit	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr16_-_67970990 Show fit	5.68	ENST00000358514.4	PSMB10 Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, beta type, 10
chr17_-_4643114 Show fit	5.41	ENST00000293778.6	CXCL16 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X-C motif) ligand 16
chr11_-_63330842 Show fit	5.35	ENST00000255695.1	HRASLS2 Ensembl NCBI GeneCards UniProt Show fit	HRAS-like suppressor 2
chr6_+_26365443 Show fit	5.33	ENST00000527422.1 ENST00000356386.2 ENST00000396934.3 ENST00000377708.2 ENST00000396948.1 ENST00000508906.2	BTN3A2 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin, subfamily 3, member A2
chr5_-_149792295 Show fit	5.33	ENST00000518797.1 ENST00000524315.1 ENST00000009530.7 ENST00000377795.3	CD74 Ensembl NCBI GeneCards UniProt Show fit	CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_+_26440700 Show fit	5.09	ENST00000494393.1 ENST00000482451.1 ENST00000244519.2 ENST00000339789.4 ENST00000471353.1 ENST00000361232.3 ENST00000487627.1 ENST00000496719.1 ENST00000490254.1 ENST00000487272.1	BTN3A3 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin, subfamily 3, member A3
chr6_+_32811885 Show fit	5.02	ENST00000458296.1 ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1	TAPSAR1 Ensembl NCBI GeneCards UniProt Show fit PSMB9 Ensembl NCBI GeneCards UniProt Show fit	TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9
chr10_+_91174314 Show fit	4.99	ENST00000371795.4	IFIT5 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 5
chr22_+_18632666 Show fit	4.88	ENST00000215794.7	USP18 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 18
chr7_-_122526499 Show fit	4.87	ENST00000412584.2	CADPS2 Ensembl NCBI GeneCards UniProt Show fit	Ca++-dependent secretion activator 2
chr5_-_35938674 Show fit	4.84	ENST00000397366.1 ENST00000513623.1 ENST00000514524.1 ENST00000397367.2	CAPSL Ensembl NCBI GeneCards UniProt Show fit	calcyphosine-like
chr17_-_40264692 Show fit	4.75	ENST00000591220.1 ENST00000251642.3	DHX58 Ensembl NCBI GeneCards UniProt Show fit	DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_-_57335280 Show fit	4.73	ENST00000287156.4	UBE2L6 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2L 6
chr12_+_113416265 Show fit	4.59	ENST00000449768.2	OAS2 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr6_-_46889694 Show fit	4.53	ENST00000283296.7 ENST00000362015.4 ENST00000456426.2	GPR116 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 116
chr10_+_91061712 Show fit	4.52	ENST00000371826.3	IFIT2 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein with tetratricopeptide repeats 2
chr4_-_156875003 Show fit	4.45	ENST00000433477.3	CTSO Ensembl NCBI GeneCards UniProt Show fit	cathepsin O
chr9_+_74764340 Show fit	4.25	ENST00000376986.1 ENST00000358399.3	GDA Ensembl NCBI GeneCards UniProt Show fit	guanine deaminase
chr3_-_49851313 Show fit	4.19	ENST00000333486.3	UBA7 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-like modifier activating enzyme 7
chr6_+_32811861 Show fit	4.08	ENST00000453426.1	TAPSAR1 Ensembl NCBI GeneCards UniProt Show fit	TAP1 and PSMB8 antisense RNA 1
chr6_+_126240442 Show fit	3.98	ENST00000448104.1 ENST00000438495.1 ENST00000444128.1	NCOA7 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 7
chr9_+_74764278 Show fit	3.95	ENST00000238018.4 ENST00000376989.3	GDA Ensembl NCBI GeneCards UniProt Show fit	guanine deaminase
chr16_-_21289627 Show fit	3.95	ENST00000396023.2 ENST00000415987.2	CRYM Ensembl NCBI GeneCards UniProt Show fit	crystallin, mu
chr8_+_144640477 Show fit	3.94	ENST00000262580.4	GSDMD Ensembl NCBI GeneCards UniProt Show fit	gasdermin D
chr2_+_231191875 Show fit	3.91	ENST00000444636.1 ENST00000415673.2 ENST00000243810.6 ENST00000396563.4	SP140L Ensembl NCBI GeneCards UniProt Show fit	SP140 nuclear body protein-like
chr22_-_36556821 Show fit	3.86	ENST00000531095.1 ENST00000397293.2 ENST00000349314.2	APOL3 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L, 3
chr7_+_100728720 Show fit	3.83	ENST00000306085.6 ENST00000412507.1	TRIM56 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 56
chr16_+_57023406 Show fit	3.82	ENST00000262510.6 ENST00000308149.7 ENST00000436936.1	NLRC5 Ensembl NCBI GeneCards UniProt Show fit	NLR family, CARD domain containing 5
chr1_-_151319710 Show fit	3.73	ENST00000290524.4 ENST00000437327.1 ENST00000452513.2 ENST00000368870.2 ENST00000452671.2	RFX5 Ensembl NCBI GeneCards UniProt Show fit	regulatory factor X, 5 (influences HLA class II expression)
chr1_+_61542922 Show fit	3.69	ENST00000407417.3	NFIA Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I/A
chr14_-_67981916 Show fit	3.65	ENST00000357461.2	TMEM229B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 229B
chr7_+_150382781 Show fit	3.55	ENST00000223293.5 ENST00000474605.1	GIMAP2 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 2
chr11_+_63304273 Show fit	3.55	ENST00000439013.2 ENST00000255688.3	RARRES3 Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor responder (tazarotene induced) 3
chr12_-_91574142 Show fit	3.54	ENST00000547937.1	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr19_-_3029011 Show fit	3.54	ENST00000590536.1 ENST00000587137.1 ENST00000455444.2 ENST00000262953.6	TLE2 Ensembl NCBI GeneCards UniProt Show fit	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr2_-_55920952 Show fit	3.46	ENST00000447944.2	PNPT1 Ensembl NCBI GeneCards UniProt Show fit	polyribonucleotide nucleotidyltransferase 1
chr1_-_60392452 Show fit	3.45	ENST00000371204.3	CYP2J2 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450, family 2, subfamily J, polypeptide 2
chr11_-_4414880 Show fit	3.39	ENST00000254436.7 ENST00000543625.1	TRIM21 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 21
chr6_-_32811771 Show fit	3.32	ENST00000395339.3 ENST00000374882.3	PSMB8 Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, beta type, 8
chr3_+_97483572 Show fit	3.31	ENST00000335979.2 ENST00000394206.1	ARL6 Ensembl NCBI GeneCards UniProt Show fit	ADP-ribosylation factor-like 6
chr6_+_26402465 Show fit	3.29	ENST00000476549.2 ENST00000289361.6 ENST00000450085.2 ENST00000425234.2 ENST00000427334.1 ENST00000506698.1	BTN3A1 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin, subfamily 3, member A1
chr2_-_231084820 Show fit	3.17	ENST00000258382.5 ENST00000338556.3	SP110 Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr14_-_67955426 Show fit	3.08	ENST00000554480.1	TMEM229B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 229B
chr9_+_27109392 Show fit	3.05	ENST00000406359.4	TEK Ensembl NCBI GeneCards UniProt Show fit	TEK tyrosine kinase, endothelial
chr12_+_102271129 Show fit	3.00	ENST00000258534.8	DRAM1 Ensembl NCBI GeneCards UniProt Show fit	DNA-damage regulated autophagy modulator 1
chr22_-_50765489 Show fit	2.98	ENST00000413817.3	DENND6B Ensembl NCBI GeneCards UniProt Show fit	DENN/MADD domain containing 6B
chr20_-_47894569 Show fit	2.94	ENST00000371744.1 ENST00000371752.1 ENST00000396105.1	ZNFX1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, NFX1-type containing 1
chr14_+_94577074 Show fit	2.94	ENST00000444961.1 ENST00000448882.1 ENST00000557098.1 ENST00000554800.1 ENST00000556544.1 ENST00000298902.5 ENST00000555819.1 ENST00000557634.1 ENST00000555744.1	IFI27 Ensembl NCBI GeneCards UniProt Show fit	interferon, alpha-inducible protein 27
chr7_-_92777606 Show fit	2.86	ENST00000437805.1 ENST00000446959.1 ENST00000439952.1 ENST00000414791.1 ENST00000446033.1 ENST00000411955.1 ENST00000318238.4	SAMD9L Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 9-like
chr8_-_23540402 Show fit	2.85	ENST00000523261.1 ENST00000380871.4	NKX3-1 Ensembl NCBI GeneCards UniProt Show fit	NK3 homeobox 1
chr19_+_10196781 Show fit	2.74	ENST00000253110.11	C19orf66 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 66
chr6_-_31324943 Show fit	2.72	ENST00000412585.2 ENST00000434333.1	HLA-B Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, B
chr1_-_89531041 Show fit	2.71	ENST00000370473.4	GBP1 Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein 1, interferon-inducible
chr6_-_32920794 Show fit	2.67	ENST00000395305.3 ENST00000395303.3 ENST00000374843.4 ENST00000429234.1	HLA-DMA Ensembl NCBI GeneCards UniProt Show fit XXbac-BPG181M17.5 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DM alpha Uncharacterized protein
chr1_-_89488510 Show fit	2.65	ENST00000564665.1 ENST00000370481.4	GBP3 Ensembl NCBI GeneCards UniProt Show fit	guanylate binding protein 3
chr21_+_42798094 Show fit	2.62	ENST00000398598.3 ENST00000455164.2 ENST00000424365.1	MX1 Ensembl NCBI GeneCards UniProt Show fit	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr3_-_114477962 Show fit	2.61	ENST00000471418.1	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr1_+_104198377 Show fit	2.59	ENST00000370083.4	AMY1A Ensembl NCBI GeneCards UniProt Show fit	amylase, alpha 1A (salivary)
chr2_+_205410516 Show fit	2.54	ENST00000406610.2 ENST00000462231.1	PARD3B Ensembl NCBI GeneCards UniProt Show fit	par-3 family cell polarity regulator beta
chr3_+_122399444 Show fit	2.53	ENST00000474629.2	PARP14 Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 14
chr13_-_43566301 Show fit	2.52	ENST00000398762.3 ENST00000313640.7 ENST00000313624.7	EPSTI1 Ensembl NCBI GeneCards UniProt Show fit	epithelial stromal interaction 1 (breast)
chr12_+_102091400 Show fit	2.47	ENST00000229266.3 ENST00000549872.1	CHPT1 Ensembl NCBI GeneCards UniProt Show fit	choline phosphotransferase 1
chr11_+_1874200 Show fit	2.42	ENST00000311604.3	LSP1 Ensembl NCBI GeneCards UniProt Show fit	lymphocyte-specific protein 1
chr6_-_87804815 Show fit	2.40	ENST00000369582.2	CGA Ensembl NCBI GeneCards UniProt Show fit	glycoprotein hormones, alpha polypeptide
chr3_-_114477787 Show fit	2.39	ENST00000464560.1	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr3_-_114343039 Show fit	2.38	ENST00000481632.1	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr4_-_46996424 Show fit	2.35	ENST00000264318.3	GABRA4 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr6_-_33282163 Show fit	2.29	ENST00000434618.2 ENST00000456592.2	TAPBP Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein (tapasin)
chr3_-_169530574 Show fit	2.26	ENST00000316515.7 ENST00000522830.1 ENST00000522526.2	LRRC34 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 34
chr6_+_26402517 Show fit	2.25	ENST00000414912.2	BTN3A1 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin, subfamily 3, member A1
chr1_+_236687881 Show fit	2.22	ENST00000526634.1	LGALS8 Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 8
chr2_-_163175133 Show fit	2.22	ENST00000421365.2 ENST00000263642.2	IFIH1 Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr9_-_33264676 Show fit	2.17	ENST00000472232.3 ENST00000379704.2	BAG1 Ensembl NCBI GeneCards UniProt Show fit	BCL2-associated athanogene
chr6_-_133119668 Show fit	2.15	ENST00000275227.4 ENST00000538764.1	SLC18B1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 18, subfamily B, member 1
chr1_+_118148556 Show fit	2.12	ENST00000369448.3	FAM46C Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 46, member C
chr1_+_47533160 Show fit	2.11	ENST00000334194.3	CYP4Z1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450, family 4, subfamily Z, polypeptide 1
chr14_+_91581011 Show fit	2.11	ENST00000523894.1 ENST00000522322.1 ENST00000523771.1	C14orf159 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 159
chr6_-_32821599 Show fit	2.10	ENST00000354258.4	TAP1 Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_+_18284477 Show fit	2.09	ENST00000407280.3	IFI30 Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 30
chr17_+_18380051 Show fit	2.06	ENST00000581545.1 ENST00000582333.1 ENST00000328114.6 ENST00000412421.2 ENST00000583322.1 ENST00000584941.1	LGALS9C Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 9C
chr11_-_64764435 Show fit	2.06	ENST00000534177.1 ENST00000301887.4	BATF2 Ensembl NCBI GeneCards UniProt Show fit	basic leucine zipper transcription factor, ATF-like 2
chr8_+_143808605 Show fit	2.03	ENST00000336138.3	THEM6 Ensembl NCBI GeneCards UniProt Show fit	thioesterase superfamily member 6
chr17_-_43339474 Show fit	2.02	ENST00000331780.4	SPATA32 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 32
chr6_+_37400974 Show fit	2.02	ENST00000455891.1 ENST00000373451.4	CMTR1 Ensembl NCBI GeneCards UniProt Show fit	cap methyltransferase 1
chr10_-_71169031 Show fit	2.01	ENST00000373307.1	TACR2 Ensembl NCBI GeneCards UniProt Show fit	tachykinin receptor 2
chr2_-_231084617 Show fit	2.01	ENST00000409815.2	SP110 Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr16_+_58283814 Show fit	2.00	ENST00000443128.2 ENST00000219299.4	CCDC113 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 113
chr11_-_4629388 Show fit	2.00	ENST00000526337.1 ENST00000300747.5	TRIM68 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 68
chr1_-_150738261 Show fit	1.99	ENST00000448301.2 ENST00000368985.3	CTSS Ensembl NCBI GeneCards UniProt Show fit	cathepsin S
chr5_-_96143602 Show fit	1.98	ENST00000443439.2 ENST00000503921.1 ENST00000508227.1 ENST00000507154.1	ERAP1 Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum aminopeptidase 1
chr9_-_75567962 Show fit	1.94	ENST00000297785.3 ENST00000376939.1	ALDH1A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family, member A1
chr7_+_134832808 Show fit	1.94	ENST00000275767.3	TMEM140 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 140
chr3_+_13590619 Show fit	1.94	ENST00000404922.3	FBLN2 Ensembl NCBI GeneCards UniProt Show fit	fibulin 2
chr17_+_25958174 Show fit	1.93	ENST00000313648.6 ENST00000577392.1 ENST00000584661.1 ENST00000413914.2	LGALS9 Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 9
chr3_+_48507210 Show fit	1.93	ENST00000433541.1 ENST00000422277.2 ENST00000436480.2 ENST00000444177.1	TREX1 Ensembl NCBI GeneCards UniProt Show fit	three prime repair exonuclease 1
chr14_+_91580777 Show fit	1.93	ENST00000525393.2 ENST00000428926.2 ENST00000517362.1	C14orf159 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 159
chr2_+_163175394 Show fit	1.92	ENST00000446271.1 ENST00000429691.2	GCA Ensembl NCBI GeneCards UniProt Show fit	grancalcin, EF-hand calcium binding protein
chrX_-_117107680 Show fit	1.92	ENST00000447671.2 ENST00000262820.3	KLHL13 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 13
chr1_+_210502238 Show fit	1.91	ENST00000545154.1 ENST00000537898.1 ENST00000391905.3 ENST00000545781.1 ENST00000261458.3 ENST00000308852.6	HHAT Ensembl NCBI GeneCards UniProt Show fit	hedgehog acyltransferase
chr17_-_43339453 Show fit	1.90	ENST00000543122.1	SPATA32 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 32
chr14_-_67981870 Show fit	1.90	ENST00000555994.1	TMEM229B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 229B
chr3_-_172241250 Show fit	1.89	ENST00000420541.2 ENST00000241261.2	TNFSF10 Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 10
chr3_+_13590636 Show fit	1.89	ENST00000295760.7	FBLN2 Ensembl NCBI GeneCards UniProt Show fit	fibulin 2
chr9_-_33264557 Show fit	1.89	ENST00000473781.1 ENST00000488499.1	BAG1 Ensembl NCBI GeneCards UniProt Show fit	BCL2-associated athanogene
chr1_-_154580616 Show fit	1.87	ENST00000368474.4	ADAR Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase, RNA-specific
chr1_+_179050512 Show fit	1.86	ENST00000367627.3	TOR3A Ensembl NCBI GeneCards UniProt Show fit	torsin family 3, member A
chr14_-_65438865 Show fit	1.86	ENST00000267512.5	RAB15 Ensembl NCBI GeneCards UniProt Show fit	RAB15, member RAS oncogene family
chr1_+_212782012 Show fit	1.86	ENST00000341491.4 ENST00000366985.1	ATF3 Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 3
chr2_+_231280954 Show fit	1.84	ENST00000409824.1 ENST00000409341.1 ENST00000409112.1 ENST00000340126.4 ENST00000341950.4	SP100 Ensembl NCBI GeneCards UniProt Show fit	SP100 nuclear antigen
chrX_-_117107542 Show fit	1.81	ENST00000371878.1	KLHL13 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 13
chr12_-_63328817 Show fit	1.80	ENST00000228705.6	PPM1H Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_+_17516531 Show fit	1.76	ENST00000528911.1 ENST00000528604.1 ENST00000595892.1 ENST00000500836.2 ENST00000598546.1 ENST00000600369.1 ENST00000598356.1 ENST00000594426.1	MVB12A Ensembl NCBI GeneCards UniProt Show fit CTD-2521M24.9 Ensembl NCBI GeneCards UniProt Show fit	multivesicular body subunit 12A CTD-2521M24.9
chr17_+_41158742 Show fit	1.75	ENST00000415816.2 ENST00000438323.2	IFI35 Ensembl NCBI GeneCards UniProt Show fit	interferon-induced protein 35
chr12_-_121477039 Show fit	1.73	ENST00000257570.5	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase-like
chr19_-_49371711 Show fit	1.73	ENST00000355496.5 ENST00000263265.6	PLEKHA4 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr7_-_80551671 Show fit	1.73	ENST00000419255.2 ENST00000544525.1	SEMA3C Ensembl NCBI GeneCards UniProt Show fit	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_99573640 Show fit	1.66	ENST00000411734.1	AZGP1 Ensembl NCBI GeneCards UniProt Show fit	alpha-2-glycoprotein 1, zinc-binding
chr1_+_241695424 Show fit	1.61	ENST00000366558.3 ENST00000366559.4	KMO Ensembl NCBI GeneCards UniProt Show fit	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_-_138453559 Show fit	1.60	ENST00000511115.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr4_-_76944621 Show fit	1.60	ENST00000306602.1	CXCL10 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X-C motif) ligand 10
chr3_-_100712352 Show fit	1.59	ENST00000471714.1 ENST00000284322.5	ABI3BP Ensembl NCBI GeneCards UniProt Show fit	ABI family, member 3 (NESH) binding protein
chr18_-_53303123 Show fit	1.58	ENST00000569357.1 ENST00000565124.1 ENST00000398339.1	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr2_+_231280908 Show fit	1.57	ENST00000427101.2 ENST00000432979.1	SP100 Ensembl NCBI GeneCards UniProt Show fit	SP100 nuclear antigen
chr15_-_37392086 Show fit	1.56	ENST00000561208.1	MEIS2 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 2
chr12_+_12223867 Show fit	1.55	ENST00000308721.5	BCL2L14 Ensembl NCBI GeneCards UniProt Show fit	BCL2-like 14 (apoptosis facilitator)
chr21_-_37451680 Show fit	1.55	ENST00000399201.1	SETD4 Ensembl NCBI GeneCards UniProt Show fit	SET domain containing 4
chr3_-_148939835 Show fit	1.54	ENST00000264613.6	CP Ensembl NCBI GeneCards UniProt Show fit	ceruloplasmin (ferroxidase)
chr17_+_76311791 Show fit	1.54	ENST00000586321.1	AC061992.2 Ensembl NCBI GeneCards UniProt Show fit	AC061992.2
chr8_+_105352050 Show fit	1.53	ENST00000297581.2	DCSTAMP Ensembl NCBI GeneCards UniProt Show fit	dendrocyte expressed seven transmembrane protein
chr5_+_96212185 Show fit	1.51	ENST00000379904.4	ERAP2 Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum aminopeptidase 2
chr15_+_71184931 Show fit	1.51	ENST00000560369.1 ENST00000260382.5	LRRC49 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 49
chr6_-_170599561 Show fit	1.51	ENST00000366756.3	DLL1 Ensembl NCBI GeneCards UniProt Show fit	delta-like 1 (Drosophila)
chr11_+_5710919 Show fit	1.50	ENST00000379965.3 ENST00000425490.1	TRIM22 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 22
chr12_-_121476959 Show fit	1.50	ENST00000339275.5	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase-like
chr2_-_231084659 Show fit	1.49	ENST00000258381.6 ENST00000358662.4 ENST00000455674.1 ENST00000392048.3	SP110 Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr19_+_10196981 Show fit	1.48	ENST00000591813.1	C19orf66 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 66
chr5_+_125695805 Show fit	1.48	ENST00000513040.1	GRAMD3 Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 3
chr1_+_174843548 Show fit	1.48	ENST00000478442.1 ENST00000465412.1	RABGAP1L Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1-like
chr14_+_91580732 Show fit	1.48	ENST00000519019.1 ENST00000523816.1 ENST00000517518.1	C14orf159 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 159
chr4_-_682932 Show fit	1.48	ENST00000404286.2	MFSD7 Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 7
chr2_+_102686820 Show fit	1.47	ENST00000409929.1 ENST00000424272.1	IL1R1 Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor, type I
chr17_-_38074842 Show fit	1.47	ENST00000309481.7	GSDMB Ensembl NCBI GeneCards UniProt Show fit	gasdermin B
chr7_-_105332084 Show fit	1.46	ENST00000472195.1	ATXN7L1 Ensembl NCBI GeneCards UniProt Show fit	ataxin 7-like 1
chr11_+_27076764 Show fit	1.45	ENST00000525090.1	BBOX1 Ensembl NCBI GeneCards UniProt Show fit	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_+_140213815 Show fit	1.44	ENST00000525929.1 ENST00000378125.3	PCDHA7 Ensembl NCBI GeneCards UniProt Show fit	protocadherin alpha 7
chr17_-_38074859 Show fit	1.43	ENST00000520542.1 ENST00000418519.1 ENST00000394179.1	GSDMB Ensembl NCBI GeneCards UniProt Show fit	gasdermin B
chr12_-_68696652 Show fit	1.42	ENST00000539972.1	MDM1 Ensembl NCBI GeneCards UniProt Show fit	Mdm1 nuclear protein homolog (mouse)
chr13_-_33002151 Show fit	1.42	ENST00000495479.1 ENST00000343281.4 ENST00000464470.1 ENST00000380139.4 ENST00000380133.2	N4BP2L1 Ensembl NCBI GeneCards UniProt Show fit	NEDD4 binding protein 2-like 1
chr5_-_124080203 Show fit	1.41	ENST00000504926.1	ZNF608 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 608
chr3_-_167371740 Show fit	1.41	ENST00000466760.1 ENST00000479765.1	WDR49 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 49
chr6_-_30181133 Show fit	1.40	ENST00000454678.2 ENST00000434785.1	TRIM26 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 26
chr3_+_48507621 Show fit	1.40	ENST00000456089.1	TREX1 Ensembl NCBI GeneCards UniProt Show fit	three prime repair exonuclease 1
chr8_-_145060593 Show fit	1.38	ENST00000313059.5 ENST00000524918.1 ENST00000313028.7 ENST00000525773.1	PARP10 Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 10
chr11_+_71710648 Show fit	1.38	ENST00000260049.5	IL18BP Ensembl NCBI GeneCards UniProt Show fit	interleukin 18 binding protein
chr8_-_79717750 Show fit	1.38	ENST00000263851.4 ENST00000379113.2	IL7 Ensembl NCBI GeneCards UniProt Show fit	interleukin 7
chr19_+_11708259 Show fit	1.38	ENST00000587939.1 ENST00000588174.1	ZNF627 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 627
chr6_-_30181156 Show fit	1.37	ENST00000418026.1 ENST00000416596.1 ENST00000453195.1	TRIM26 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 26
chr2_-_220252603 Show fit	1.37	ENST00000322176.7 ENST00000273075.4	DNPEP Ensembl NCBI GeneCards UniProt Show fit	aspartyl aminopeptidase
chr4_-_682960 Show fit	1.36	ENST00000512249.1 ENST00000515118.1 ENST00000347950.5	MFSD7 Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 7
chr11_+_71709938 Show fit	1.36	ENST00000393705.4 ENST00000337131.5 ENST00000531053.1 ENST00000404792.1	IL18BP Ensembl NCBI GeneCards UniProt Show fit	interleukin 18 binding protein
chr6_-_33281979 Show fit	1.35	ENST00000426633.2 ENST00000467025.1	TAPBP Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein (tapasin)
chr14_+_24605389 Show fit	1.35	ENST00000382708.3 ENST00000561435.1	PSME1 Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr5_-_111092930 Show fit	1.34	ENST00000257435.7	NREP Ensembl NCBI GeneCards UniProt Show fit	neuronal regeneration related protein
chr19_+_11708229 Show fit	1.33	ENST00000361113.5	ZNF627 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 627
chr10_+_92980517 Show fit	1.32	ENST00000336126.5	PCGF5 Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 5
chr17_-_76975925 Show fit	1.32	ENST00000591274.1 ENST00000589906.1 ENST00000591778.1 ENST00000589775.2 ENST00000585407.1 ENST00000262776.3	LGALS3BP Ensembl NCBI GeneCards UniProt Show fit	lectin, galactoside-binding, soluble, 3 binding protein
chr4_-_75719896 Show fit	1.32	ENST00000395743.3	BTC Ensembl NCBI GeneCards UniProt Show fit	betacellulin
chr1_+_18807424 Show fit	1.30	ENST00000400664.1	KLHDC7A Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 7A
chr17_-_33759509 Show fit	1.28	ENST00000304905.5	SLFN12 Ensembl NCBI GeneCards UniProt Show fit	schlafen family member 12
chr10_+_114135952 Show fit	1.27	ENST00000356116.1 ENST00000433418.1 ENST00000354273.4	ACSL5 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long-chain family member 5
chr4_-_146101304 Show fit	1.26	ENST00000447906.2	OTUD4 Ensembl NCBI GeneCards UniProt Show fit	OTU domain containing 4
chr13_-_30424821 Show fit	1.26	ENST00000380680.4	UBL3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-like 3
chr22_+_23487513 Show fit	1.26	ENST00000263116.2 ENST00000341989.4	RAB36 Ensembl NCBI GeneCards UniProt Show fit	RAB36, member RAS oncogene family
chr16_+_28303804 Show fit	1.25	ENST00000341901.4	SBK1 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF2_STAT2_IRF8_IRF1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	23.1	GO:0036269	swimming behavior(GO:0036269)
5.5	21.8	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
5.1	15.2	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
3.8	15.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
3.5	10.6	GO:0051097	negative regulation of helicase activity(GO:0051097)
3.4	10.1	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
3.0	15.2	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
2.4	12.0	GO:0070842	aggresome assembly(GO:0070842)
1.9	20.8	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.8	17.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
1.6	8.2	GO:0006145	purine nucleobase catabolic process(GO:0006145)
1.6	4.7	GO:0050822	peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
1.6	20.4	GO:0035457	cellular response to interferon-alpha(GO:0035457)
1.5	6.1	GO:0019542	acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
1.4	11.5	GO:1990504	dense core granule exocytosis(GO:1990504)
1.3	3.9	GO:0035915	pore formation in membrane of other organism(GO:0035915)
1.2	6.2	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
1.2	3.5	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
1.2	3.5	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.9	10.8	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.9	0.9	GO:1903991	positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.9	3.4	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.8	9.3	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.8	2.5	GO:1990108	protein linear deubiquitination(GO:1990108)
0.8	3.3	GO:1903445	intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.7	5.7	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.7	1.4	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.7	2.8	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.7	2.0	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.7	2.7	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.7	5.2	GO:0018377	protein myristoylation(GO:0018377)
0.6	1.9	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5	4.8	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.5	2.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.5	1.5	GO:0034241	macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.5	1.5	GO:0048633	negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.5	1.5	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5	1.9	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5	2.9	GO:2000834	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.5	10.9	GO:0072643	interferon-gamma secretion(GO:0072643)
0.5	1.9	GO:0046725	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.5	4.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.4	2.2	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.4	2.2	GO:0031296	B cell costimulation(GO:0031296)
0.4	2.6	GO:0030421	defecation(GO:0030421)
0.4	11.9	GO:0035456	response to interferon-beta(GO:0035456)
0.4	1.6	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.4	1.9	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.4	2.7	GO:0048014	Tie signaling pathway(GO:0048014)
0.4	1.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.4	3.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4	1.1	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.3	1.0	GO:0032289	central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3	34.7	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.3	9.9	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.3	1.9	GO:0052565	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.3	7.1	GO:0010818	T cell chemotaxis(GO:0010818)
0.3	0.6	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.3	0.9	GO:0071418	cellular response to amine stimulus(GO:0071418)
0.3	4.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.3	2.0	GO:0080009	mRNA methylation(GO:0080009)
0.3	1.7	GO:0003350	pulmonary myocardium development(GO:0003350)
0.3	0.8	GO:0070541	response to platinum ion(GO:0070541)
0.3	3.8	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3	0.8	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3	0.8	GO:0003275	apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3	2.3	GO:2001023	regulation of response to drug(GO:2001023)
0.3	1.3	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.2	4.0	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2	1.2	GO:0019075	virus maturation(GO:0019075)
0.2	1.0	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.2	1.0	GO:2000491	cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	0.7	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.2	0.9	GO:0007402	ganglion mother cell fate determination(GO:0007402)
0.2	0.5	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2	1.8	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2	1.1	GO:0045349	negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.2	0.9	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2	0.9	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.2	0.6	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.2	7.9	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	1.0	GO:0048686	regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2	0.8	GO:0072695	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2	1.0	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.2	1.2	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.2	0.6	GO:1902955	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2	0.6	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2	0.4	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2	2.5	GO:0070327	thyroid hormone transport(GO:0070327)
0.2	9.7	GO:0032608	interferon-beta production(GO:0032608)
0.2	3.5	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.2	4.5	GO:0072189	ureter development(GO:0072189)
0.2	1.0	GO:0070560	protein secretion by platelet(GO:0070560)
0.2	1.0	GO:0038161	prolactin signaling pathway(GO:0038161)
0.2	2.0	GO:0016584	nucleosome positioning(GO:0016584)
0.2	0.3	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2	0.6	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.2	0.5	GO:0070904	L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.2	0.8	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.9	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.1	0.9	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.4	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.1	0.7	GO:0003014	renal system process(GO:0003014)
0.1	1.3	GO:0045345	positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1	0.3	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	3.4	GO:1900115	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.7	GO:0034127	detection of lipopolysaccharide(GO:0032497) regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1	1.9	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.1	0.8	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	1.5	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.1	1.4	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	6.4	GO:0006536	glutamate metabolic process(GO:0006536)
0.1	2.4	GO:0006968	cellular defense response(GO:0006968)
0.1	0.4	GO:0051758	homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1	1.5	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.6	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
0.1	1.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	1.9	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.1	1.8	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.1	1.5	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.8	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.4	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.4	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.1	0.8	GO:0033590	response to cobalamin(GO:0033590)
0.1	3.6	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1	0.5	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1	0.5	GO:0045204	MAPK export from nucleus(GO:0045204)
0.1	0.7	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.1	0.4	GO:0043335	protein unfolding(GO:0043335)
0.1	0.3	GO:0060139	positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1	0.5	GO:0015692	lead ion transport(GO:0015692)
0.1	0.3	GO:0046968	peptide antigen transport(GO:0046968)
0.1	0.6	GO:0022604	regulation of cell morphogenesis(GO:0022604)
0.1	0.1	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
0.1	0.4	GO:0039516	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	2.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.1	3.1	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1	2.6	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.1	0.6	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	2.7	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	4.5	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.1	0.1	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1	0.5	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.2	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1	0.7	GO:0015793	glycerol transport(GO:0015793)
0.1	0.2	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1	0.5	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1	0.6	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.1	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.1	0.2	GO:0007520	myoblast fusion(GO:0007520)
0.1	0.2	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1	0.4	GO:0071220	toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1	0.2	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.1	1.0	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	0.1	GO:0060809	mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1	0.3	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.7	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.8	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1	0.3	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1	1.7	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.7	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.5	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.3	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1	0.5	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.1	1.0	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	0.3	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.6	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1	0.3	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	10.3	GO:0007286	spermatid development(GO:0007286)
0.1	0.2	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1	2.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	0.2	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1	1.5	GO:0006825	copper ion transport(GO:0006825)
0.1	0.4	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.3	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.1	0.6	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	1.4	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.4	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	0.5	GO:0021678	third ventricle development(GO:0021678)
0.1	0.5	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.2	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	0.6	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.4	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.9	GO:0006020	inositol metabolic process(GO:0006020)
0.1	1.0	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.1	0.3	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.3	GO:0002758	innate immune response-activating signal transduction(GO:0002758)
0.1	1.3	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	0.8	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1	0.6	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	2.0	GO:0071711	basement membrane organization(GO:0071711)
0.0	0.6	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.1	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0	0.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	2.4	GO:0006298	mismatch repair(GO:0006298)
0.0	0.8	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.0	1.0	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.3	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0	1.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.2	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.4	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.1	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.0	1.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.2	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.0	0.5	GO:0006228	UTP biosynthetic process(GO:0006228)
0.0	1.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.7	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0	0.5	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.2	GO:0085020	protein K6-linked ubiquitination(GO:0085020) regulation of kinetochore assembly(GO:0090234)
0.0	0.1	GO:0036309	protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0	0.2	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.1	GO:0032242	regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0	0.5	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.0	1.8	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.9	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.2	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.5	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.7	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.6	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.5	GO:0097104	postsynaptic membrane assembly(GO:0097104)
0.0	0.3	GO:0008343	adult feeding behavior(GO:0008343) behavioral response to ethanol(GO:0048149)
0.0	0.3	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	1.3	GO:2001240	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0	0.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.2	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0	0.2	GO:2000121	regulation of removal of superoxide radicals(GO:2000121)
0.0	0.1	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0050918	positive chemotaxis(GO:0050918)
0.0	0.3	GO:0002778	antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.0	1.0	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	1.0	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0071351	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0	0.1	GO:0060926	cardiac pacemaker cell development(GO:0060926) sinoatrial node cell development(GO:0060931)
0.0	1.5	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.3	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.3	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.6	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.1	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0	1.0	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.7	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.2	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.3	GO:0015747	urate transport(GO:0015747)
0.0	0.2	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.6	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	1.0	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.4	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.2	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0	0.5	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.3	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.2	GO:1900038	negative regulation of cellular response to hypoxia(GO:1900038)
0.0	0.4	GO:0002385	mucosal immune response(GO:0002385)
0.0	0.5	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.2	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0	0.5	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.2	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:1902952	regulation of postsynaptic density protein 95 clustering(GO:1902897) positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0	0.1	GO:0021853	cerebral cortex tangential migration(GO:0021800) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.2	GO:1902221	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.6	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.8	GO:0008542	visual learning(GO:0008542)
0.0	0.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.4	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.4	GO:0006458	'de novo' protein folding(GO:0006458)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.9	GO:0051603	proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0	1.3	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.4	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	1.5	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.8	GO:0009988	cell-cell recognition(GO:0009988)
0.0	1.0	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.6	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	2.4	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.3	GO:2001222	regulation of neuron migration(GO:2001222)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.2	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0	0.1	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0	0.1	GO:0045629	positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.3	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	1.7	GO:0007586	digestion(GO:0007586)
0.0	0.7	GO:0006400	tRNA modification(GO:0006400)
0.0	0.6	GO:0003341	cilium movement(GO:0003341)
0.0	0.0	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.7	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.2	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	30.0	GO:1990111	spermatoproteasome complex(GO:1990111)
3.3	19.9	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.8	5.3	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.7	3.3	GO:0005879	axonemal microtubule(GO:0005879)
0.6	1.9	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.6	4.1	GO:0042825	TAP complex(GO:0042825)
0.5	3.3	GO:0008537	proteasome activator complex(GO:0008537)
0.5	4.2	GO:0030870	Mre11 complex(GO:0030870)
0.4	1.9	GO:0044530	supraspliceosomal complex(GO:0044530)
0.3	1.0	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3	3.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.3	1.2	GO:0031213	RSF complex(GO:0031213)
0.3	0.3	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.3	27.6	GO:0035577	azurophil granule membrane(GO:0035577)
0.3	0.8	GO:0072534	perineuronal net(GO:0072534)
0.3	3.8	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	1.6	GO:0097179	protease inhibitor complex(GO:0097179)
0.3	4.5	GO:0008385	IkappaB kinase complex(GO:0008385)
0.2	3.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.2	2.5	GO:0042788	polysomal ribosome(GO:0042788)
0.2	0.6	GO:0001534	radial spoke(GO:0001534)
0.2	2.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.2	11.5	GO:0016235	aggresome(GO:0016235)
0.1	10.4	GO:0005643	nuclear pore(GO:0005643)
0.1	0.3	GO:0000785	chromatin(GO:0000785)
0.1	0.7	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	2.7	GO:0042611	MHC protein complex(GO:0042611)
0.1	1.4	GO:0000439	core TFIIH complex(GO:0000439)
0.1	12.3	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.1	20.3	GO:0032587	ruffle membrane(GO:0032587)
0.1	0.9	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	0.5	GO:0070826	paraferritin complex(GO:0070826)
0.1	1.7	GO:0033391	chromatoid body(GO:0033391)
0.1	0.7	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.7	GO:0071438	invadopodium membrane(GO:0071438)
0.1	9.1	GO:0005811	lipid particle(GO:0005811)
0.1	1.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	0.6	GO:0032009	early phagosome(GO:0032009)
0.1	0.9	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	9.5	GO:0042734	presynaptic membrane(GO:0042734)
0.1	1.9	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	2.3	GO:1902711	GABA-A receptor complex(GO:1902711)
0.1	0.3	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.8	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	1.0	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	5.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	3.8	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	0.8	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.1	1.8	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.3	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.1	0.6	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	1.1	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	1.0	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.0	0.9	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	1.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.9	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	2.7	GO:0097542	ciliary tip(GO:0097542)
0.0	0.7	GO:0000124	SAGA complex(GO:0000124)
0.0	0.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	1.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	3.1	GO:0015030	Cajal body(GO:0015030)
0.0	0.3	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.0	0.2	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.3	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.4	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.0	3.5	GO:0005776	autophagosome(GO:0005776)
0.0	2.5	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0061617	MICOS complex(GO:0061617)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0036398	TCR signalosome(GO:0036398)
0.0	0.7	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.8	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.4	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	7.7	GO:0031965	nuclear membrane(GO:0031965)
0.0	5.9	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	1.0	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.7	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.3	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.3	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	45.8	GO:0005739	mitochondrion(GO:0005739)
0.0	0.6	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.5	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	1.9	GO:0005923	bicellular tight junction(GO:0005923)
0.0	1.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0097447	dendritic tree(GO:0097447)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.6	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.5	GO:0043034	costamere(GO:0043034)
0.0	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:1902560	GMP reductase complex(GO:1902560)
0.0	1.0	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	11.6	GO:0000139	Golgi membrane(GO:0000139)
0.0	0.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	2.2	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.6	GO:0034707	chloride channel complex(GO:0034707)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.7	23.1	GO:0033754	indoleamine 2,3-dioxygenase activity(GO:0033754)
3.8	15.2	GO:0009041	uridylate kinase activity(GO:0009041)
1.9	15.3	GO:0019763	immunoglobulin receptor activity(GO:0019763)
1.7	6.8	GO:0031849	olfactory receptor binding(GO:0031849)
1.3	6.4	GO:0047820	D-glutamate cyclase activity(GO:0047820)
1.3	3.8	GO:0042007	interleukin-18 binding(GO:0042007)
1.2	8.7	GO:0046979	TAP2 binding(GO:0046979)
1.2	6.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.0	30.7	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.0	3.9	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.9	4.4	GO:0042289	MHC class II protein binding(GO:0042289)
0.7	8.6	GO:0031386	protein tag(GO:0031386)
0.7	4.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.6	2.6	GO:0016160	amylase activity(GO:0016160)
0.6	5.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.6	2.5	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.6	12.0	GO:0070628	proteasome binding(GO:0070628)
0.5	3.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.5	2.9	GO:0004882	androgen receptor activity(GO:0004882)
0.5	3.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.4	3.9	GO:1901612	cardiolipin binding(GO:1901612)
0.4	1.3	GO:0008859	exoribonuclease II activity(GO:0008859)
0.4	3.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.4	2.5	GO:0034046	poly(G) binding(GO:0034046)
0.4	2.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.4	1.9	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4	1.9	GO:0048030	disaccharide binding(GO:0048030)
0.4	1.5	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4	1.5	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3	9.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.3	42.0	GO:0003727	single-stranded RNA binding(GO:0003727)
0.3	4.6	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.3	0.9	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.3	1.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.3	1.2	GO:0005151	interleukin-1, Type II receptor binding(GO:0005151)
0.3	2.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.3	1.2	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.3	1.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3	3.4	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	1.0	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2	5.6	GO:0070330	aromatase activity(GO:0070330)
0.2	6.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.2	4.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	0.4	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.2	1.1	GO:0097001	ceramide binding(GO:0097001)
0.2	0.6	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.2	0.8	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.2	1.0	GO:0004925	prolactin receptor activity(GO:0004925)
0.2	1.5	GO:0031996	thioesterase binding(GO:0031996)
0.2	2.5	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.2	1.7	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.2	0.9	GO:0005499	vitamin D binding(GO:0005499)
0.2	0.5	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2	1.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	1.5	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	2.3	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.2	1.0	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.2	0.9	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.2	0.5	GO:0008523	L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2	2.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	0.6	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.4	GO:0051499	D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1	1.9	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	2.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.7	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.1	1.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	1.0	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	0.7	GO:0015254	glycerol channel activity(GO:0015254)
0.1	1.5	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	2.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.8	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	2.6	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.1	3.7	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.6	GO:0042625	ATPase coupled ion transmembrane transporter activity(GO:0042625)
0.1	5.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	4.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	5.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	0.3	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.6	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.2	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
0.1	0.9	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	0.6	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.1	2.8	GO:0005521	lamin binding(GO:0005521)
0.1	0.5	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1	3.4	GO:0004623	phospholipase A2 activity(GO:0004623)
0.1	0.9	GO:0019864	IgG binding(GO:0019864)
0.1	0.5	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1	48.8	GO:0005525	GTP binding(GO:0005525)
0.1	0.2	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1	1.4	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.6	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.7	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	1.0	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.1	1.6	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.5	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
0.1	0.2	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
0.1	0.2	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.1	0.9	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	0.2	GO:0033149	FFAT motif binding(GO:0033149)
0.1	0.6	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	1.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.8	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.1	3.0	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	5.4	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1	1.0	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	0.6	GO:0035325	Toll-like receptor binding(GO:0035325)
0.1	0.4	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	3.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	2.0	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0016608	growth hormone-releasing hormone activity(GO:0016608)
0.1	1.8	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.5	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.0	0.7	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.9	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.9	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	1.3	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.3	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	1.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.4	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.7	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	5.9	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.8	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.5	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.8	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0	0.5	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	3.6	GO:0005518	collagen binding(GO:0005518)
0.0	1.1	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	2.7	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	1.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.7	GO:0002039	p53 binding(GO:0002039)
0.0	0.6	GO:0005549	odorant binding(GO:0005549)
0.0	1.5	GO:0019239	deaminase activity(GO:0019239)
0.0	0.5	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	10.8	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.6	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.3	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	1.1	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.9	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	1.9	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.9	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.7	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0016403	dimethylargininase activity(GO:0016403)
0.0	2.1	GO:0016279	protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	2.1	GO:0003712	transcription cofactor activity(GO:0003712)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.5	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.8	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	3.7	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	1.5	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0	0.5	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	1.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.6	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.2	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.4	GO:0004407	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0	7.1	GO:0001159	core promoter proximal region DNA binding(GO:0001159)
0.0	1.0	GO:0050136	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.9	GO:0030507	spectrin binding(GO:0030507)
0.0	2.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	1.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.6	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	4.3	GO:0016746	transferase activity, transferring acyl groups(GO:0016746)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0031208	POZ domain binding(GO:0031208)
0.0	0.3	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.0	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.6	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.1	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	7.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.4	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.4	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.6	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.3	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	1.2	GO:0032182	ubiquitin-like protein binding(GO:0032182)
0.0	0.4	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.0	0.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0031730	CCR1 chemokine receptor binding(GO:0031726) CCR5 chemokine receptor binding(GO:0031730)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	6.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	1.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	7.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	2.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	7.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	2.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	3.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	2.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.9	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	3.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	1.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	8.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	1.6	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	2.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	2.9	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.9	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.2	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	1.4	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	1.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	2.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.8	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	1.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.9	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.7	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	1.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	2.4	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	2.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	3.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	25.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.1	21.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.0	97.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.6	8.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.6	2.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	8.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	30.9	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.3	14.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3	2.6	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.2	2.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	1.5	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	3.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	4.1	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1	0.8	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.0	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	5.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.0	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.1	1.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	3.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	1.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	2.1	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	2.2	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.1	1.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.8	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.8	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	1.0	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	4.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	2.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.3	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.4	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins

Results for IRF2_STAT2_IRF8_IRF1

Z-value: 2.40

Motif logo

Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Activity-expression correlation:

Activity profile of IRF2_STAT2_IRF8_IRF1 motif

Sorted Z-values of IRF2_STAT2_IRF8_IRF1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF2_STAT2_IRF8_IRF1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: