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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRF2_STAT2_IRF8_IRF1

Z-value: 2.40

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Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Gene Symbol Gene ID Gene Info
IRF2
ENSG00000168310.6 interferon regulatory factor 2
STAT2
ENSG00000170581.9 signal transducer and activator of transcription 2
IRF8
ENSG00000140968.6 interferon regulatory factor 8
IRF1
ENSG00000125347.9 interferon regulatory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF1hg19_v2_chr5_-_131826457_1318265140.882.2e-10Click!
STAT2hg19_v2_chr12_-_56753858_567539300.532.4e-03Click!
IRF8hg19_v2_chr16_+_85942594_859426350.144.7e-01Click!
IRF2hg19_v2_chr4_-_185395672_1853957340.125.3e-01Click!

Activity profile of IRF2_STAT2_IRF8_IRF1 motif

Sorted Z-values of IRF2_STAT2_IRF8_IRF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_39770803 23.15 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr6_+_32821924 15.95 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr1_-_207119738 15.18 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr2_-_7005785 15.17 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr21_+_42733870 12.53 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr6_-_29527702 12.00 ENST00000377050.4
UBD
ubiquitin D
chr1_+_79115503 11.81 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr1_+_79086088 11.02 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr9_-_32526184 10.97 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr10_+_91152303 10.56 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr4_-_169239921 10.25 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr19_-_17516449 10.05 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr1_-_27998689 9.84 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
IFI6
interferon, alpha-inducible protein 6
chr17_+_6659153 8.69 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr1_+_948803 8.56 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr9_-_32526299 8.49 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr10_+_91087651 8.24 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_+_91092241 7.61 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr3_+_187086120 7.09 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr17_+_4643337 6.82 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr7_-_122526799 6.67 ENST00000334010.7
ENST00000313070.7
CADPS2
Ca++-dependent secretion activator 2
chr2_+_7017796 6.17 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr17_+_4643300 6.16 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr20_-_25038804 6.12 ENST00000323482.4
ACSS1
acyl-CoA synthetase short-chain family member 1
chr12_+_6561190 6.02 ENST00000544021.1
ENST00000266556.7
TAPBPL
TAP binding protein-like
chr21_+_42792442 5.69 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr16_-_67970990 5.68 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr17_-_4643114 5.41 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr11_-_63330842 5.35 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr6_+_26365443 5.33 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr5_-_149792295 5.33 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_+_26440700 5.09 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr6_+_32811885 5.02 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr10_+_91174314 4.99 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr22_+_18632666 4.88 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr7_-_122526499 4.87 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr5_-_35938674 4.84 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr17_-_40264692 4.75 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_-_57335280 4.73 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr12_+_113416265 4.59 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr6_-_46889694 4.53 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116
G protein-coupled receptor 116
chr10_+_91061712 4.52 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr4_-_156875003 4.45 ENST00000433477.3
CTSO
cathepsin O
chr9_+_74764340 4.25 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr3_-_49851313 4.19 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr6_+_32811861 4.08 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr6_+_126240442 3.98 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr9_+_74764278 3.95 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr16_-_21289627 3.95 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr8_+_144640477 3.94 ENST00000262580.4
GSDMD
gasdermin D
chr2_+_231191875 3.91 ENST00000444636.1
ENST00000415673.2
ENST00000243810.6
ENST00000396563.4
SP140L
SP140 nuclear body protein-like
chr22_-_36556821 3.86 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr7_+_100728720 3.83 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr16_+_57023406 3.82 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLRC5
NLR family, CARD domain containing 5
chr1_-_151319710 3.73 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr1_+_61542922 3.69 ENST00000407417.3
NFIA
nuclear factor I/A
chr14_-_67981916 3.65 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr7_+_150382781 3.55 ENST00000223293.5
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr11_+_63304273 3.55 ENST00000439013.2
ENST00000255688.3
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr12_-_91574142 3.54 ENST00000547937.1
DCN
decorin
chr19_-_3029011 3.54 ENST00000590536.1
ENST00000587137.1
ENST00000455444.2
ENST00000262953.6
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr2_-_55920952 3.46 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr1_-_60392452 3.45 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr11_-_4414880 3.39 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr6_-_32811771 3.32 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr3_+_97483572 3.31 ENST00000335979.2
ENST00000394206.1
ARL6
ADP-ribosylation factor-like 6
chr6_+_26402465 3.29 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr2_-_231084820 3.17 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr14_-_67955426 3.08 ENST00000554480.1
TMEM229B
transmembrane protein 229B
chr9_+_27109392 3.05 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr12_+_102271129 3.00 ENST00000258534.8
DRAM1
DNA-damage regulated autophagy modulator 1
chr22_-_50765489 2.98 ENST00000413817.3
DENND6B
DENN/MADD domain containing 6B
chr20_-_47894569 2.94 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
ZNFX1
zinc finger, NFX1-type containing 1
chr14_+_94577074 2.94 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr7_-_92777606 2.86 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr8_-_23540402 2.85 ENST00000523261.1
ENST00000380871.4
NKX3-1
NK3 homeobox 1
chr19_+_10196781 2.74 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr6_-_31324943 2.72 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr1_-_89531041 2.71 ENST00000370473.4
GBP1
guanylate binding protein 1, interferon-inducible
chr6_-_32920794 2.67 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr1_-_89488510 2.65 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr21_+_42798094 2.62 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr3_-_114477962 2.61 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_104198377 2.59 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chr2_+_205410516 2.54 ENST00000406610.2
ENST00000462231.1
PARD3B
par-3 family cell polarity regulator beta
chr3_+_122399444 2.53 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr13_-_43566301 2.52 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr12_+_102091400 2.47 ENST00000229266.3
ENST00000549872.1
CHPT1
choline phosphotransferase 1
chr11_+_1874200 2.42 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr6_-_87804815 2.40 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr3_-_114477787 2.39 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_114343039 2.38 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_46996424 2.35 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr6_-_33282163 2.29 ENST00000434618.2
ENST00000456592.2
TAPBP
TAP binding protein (tapasin)
chr3_-_169530574 2.26 ENST00000316515.7
ENST00000522830.1
ENST00000522526.2
LRRC34
leucine rich repeat containing 34
chr6_+_26402517 2.25 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr1_+_236687881 2.22 ENST00000526634.1
LGALS8
lectin, galactoside-binding, soluble, 8
chr2_-_163175133 2.22 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr9_-_33264676 2.17 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr6_-_133119668 2.15 ENST00000275227.4
ENST00000538764.1
SLC18B1
solute carrier family 18, subfamily B, member 1
chr1_+_118148556 2.12 ENST00000369448.3
FAM46C
family with sequence similarity 46, member C
chr1_+_47533160 2.11 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr14_+_91581011 2.11 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr6_-_32821599 2.10 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_+_18284477 2.09 ENST00000407280.3
IFI30
interferon, gamma-inducible protein 30
chr17_+_18380051 2.06 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr11_-_64764435 2.06 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr8_+_143808605 2.03 ENST00000336138.3
THEM6
thioesterase superfamily member 6
chr17_-_43339474 2.02 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr6_+_37400974 2.02 ENST00000455891.1
ENST00000373451.4
CMTR1
cap methyltransferase 1
chr10_-_71169031 2.01 ENST00000373307.1
TACR2
tachykinin receptor 2
chr2_-_231084617 2.01 ENST00000409815.2
SP110
SP110 nuclear body protein
chr16_+_58283814 2.00 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr11_-_4629388 2.00 ENST00000526337.1
ENST00000300747.5
TRIM68
tripartite motif containing 68
chr1_-_150738261 1.99 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr5_-_96143602 1.98 ENST00000443439.2
ENST00000503921.1
ENST00000508227.1
ENST00000507154.1
ERAP1
endoplasmic reticulum aminopeptidase 1
chr9_-_75567962 1.94 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr7_+_134832808 1.94 ENST00000275767.3
TMEM140
transmembrane protein 140
chr3_+_13590619 1.94 ENST00000404922.3
FBLN2
fibulin 2
chr17_+_25958174 1.93 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr3_+_48507210 1.93 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr14_+_91580777 1.93 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr2_+_163175394 1.92 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chrX_-_117107680 1.92 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13
chr1_+_210502238 1.91 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
HHAT
hedgehog acyltransferase
chr17_-_43339453 1.90 ENST00000543122.1
SPATA32
spermatogenesis associated 32
chr14_-_67981870 1.90 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr3_-_172241250 1.89 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr3_+_13590636 1.89 ENST00000295760.7
FBLN2
fibulin 2
chr9_-_33264557 1.89 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr1_-_154580616 1.87 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr1_+_179050512 1.86 ENST00000367627.3
TOR3A
torsin family 3, member A
chr14_-_65438865 1.86 ENST00000267512.5
RAB15
RAB15, member RAS oncogene family
chr1_+_212782012 1.86 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr2_+_231280954 1.84 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chrX_-_117107542 1.81 ENST00000371878.1
KLHL13
kelch-like family member 13
chr12_-_63328817 1.80 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_+_17516531 1.76 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
CTD-2521M24.9
chr17_+_41158742 1.75 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr12_-_121477039 1.73 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr19_-_49371711 1.73 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr7_-_80551671 1.73 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_99573640 1.66 ENST00000411734.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr1_+_241695424 1.61 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_-_138453559 1.60 ENST00000511115.1
PCDH18
protocadherin 18
chr4_-_76944621 1.60 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr3_-_100712352 1.59 ENST00000471714.1
ENST00000284322.5
ABI3BP
ABI family, member 3 (NESH) binding protein
chr18_-_53303123 1.58 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr2_+_231280908 1.57 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr15_-_37392086 1.56 ENST00000561208.1
MEIS2
Meis homeobox 2
chr12_+_12223867 1.55 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr21_-_37451680 1.55 ENST00000399201.1
SETD4
SET domain containing 4
chr3_-_148939835 1.54 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr17_+_76311791 1.54 ENST00000586321.1
AC061992.2
AC061992.2
chr8_+_105352050 1.53 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr5_+_96212185 1.51 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr15_+_71184931 1.51 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr6_-_170599561 1.51 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr11_+_5710919 1.50 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr12_-_121476959 1.50 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr2_-_231084659 1.49 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr19_+_10196981 1.48 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr5_+_125695805 1.48 ENST00000513040.1
GRAMD3
GRAM domain containing 3
chr1_+_174843548 1.48 ENST00000478442.1
ENST00000465412.1
RABGAP1L
RAB GTPase activating protein 1-like
chr14_+_91580732 1.48 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr4_-_682932 1.48 ENST00000404286.2
MFSD7
major facilitator superfamily domain containing 7
chr2_+_102686820 1.47 ENST00000409929.1
ENST00000424272.1
IL1R1
interleukin 1 receptor, type I
chr17_-_38074842 1.47 ENST00000309481.7
GSDMB
gasdermin B
chr7_-_105332084 1.46 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr11_+_27076764 1.45 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_+_140213815 1.44 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr17_-_38074859 1.43 ENST00000520542.1
ENST00000418519.1
ENST00000394179.1
GSDMB
gasdermin B
chr12_-_68696652 1.42 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr13_-_33002151 1.42 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
N4BP2L1
NEDD4 binding protein 2-like 1
chr5_-_124080203 1.41 ENST00000504926.1
ZNF608
zinc finger protein 608
chr3_-_167371740 1.41 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chr6_-_30181133 1.40 ENST00000454678.2
ENST00000434785.1
TRIM26
tripartite motif containing 26
chr3_+_48507621 1.40 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr8_-_145060593 1.38 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr11_+_71710648 1.38 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr8_-_79717750 1.38 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr19_+_11708259 1.38 ENST00000587939.1
ENST00000588174.1
ZNF627
zinc finger protein 627
chr6_-_30181156 1.37 ENST00000418026.1
ENST00000416596.1
ENST00000453195.1
TRIM26
tripartite motif containing 26
chr2_-_220252603 1.37 ENST00000322176.7
ENST00000273075.4
DNPEP
aspartyl aminopeptidase
chr4_-_682960 1.36 ENST00000512249.1
ENST00000515118.1
ENST00000347950.5
MFSD7
major facilitator superfamily domain containing 7
chr11_+_71709938 1.36 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr6_-_33281979 1.35 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr14_+_24605389 1.35 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr5_-_111092930 1.34 ENST00000257435.7
NREP
neuronal regeneration related protein
chr19_+_11708229 1.33 ENST00000361113.5
ZNF627
zinc finger protein 627
chr10_+_92980517 1.32 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr17_-_76975925 1.32 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr4_-_75719896 1.32 ENST00000395743.3
BTC
betacellulin
chr1_+_18807424 1.30 ENST00000400664.1
KLHDC7A
kelch domain containing 7A
chr17_-_33759509 1.28 ENST00000304905.5
SLFN12
schlafen family member 12
chr10_+_114135952 1.27 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_-_146101304 1.26 ENST00000447906.2
OTUD4
OTU domain containing 4
chr13_-_30424821 1.26 ENST00000380680.4
UBL3
ubiquitin-like 3
chr22_+_23487513 1.26 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr16_+_28303804 1.25 ENST00000341901.4
SBK1
SH3 domain binding kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF2_STAT2_IRF8_IRF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 23.1 GO:0036269 swimming behavior(GO:0036269)
5.5 21.8 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
5.1 15.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
3.8 15.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
3.5 10.6 GO:0051097 negative regulation of helicase activity(GO:0051097)
3.4 10.1 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
3.0 15.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
2.4 12.0 GO:0070842 aggresome assembly(GO:0070842)
1.9 20.8 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.8 17.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.6 8.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
1.6 4.7 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
1.6 20.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.5 6.1 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
1.4 11.5 GO:1990504 dense core granule exocytosis(GO:1990504)
1.3 3.9 GO:0035915 pore formation in membrane of other organism(GO:0035915)
1.2 6.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
1.2 3.5 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
1.2 3.5 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.9 10.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.9 0.9 GO:1903991 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.9 3.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.8 9.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.8 2.5 GO:1990108 protein linear deubiquitination(GO:1990108)
0.8 3.3 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.7 5.7 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.7 1.4 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.7 2.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.7 2.0 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.7 2.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.7 5.2 GO:0018377 protein myristoylation(GO:0018377)
0.6 1.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 4.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.5 2.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.5 1.5 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.5 1.5 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.5 1.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5 1.9 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 2.9 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.5 10.9 GO:0072643 interferon-gamma secretion(GO:0072643)
0.5 1.9 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.5 4.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.4 2.2 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.4 2.2 GO:0031296 B cell costimulation(GO:0031296)
0.4 2.6 GO:0030421 defecation(GO:0030421)
0.4 11.9 GO:0035456 response to interferon-beta(GO:0035456)
0.4 1.6 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.4 1.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 2.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 3.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 1.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.3 1.0 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3 34.7 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.3 9.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.3 1.9 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.3 7.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.3 0.6 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 0.9 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.3 4.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 2.0 GO:0080009 mRNA methylation(GO:0080009)
0.3 1.7 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 0.8 GO:0070541 response to platinum ion(GO:0070541)
0.3 3.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 0.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 0.8 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3 2.3 GO:2001023 regulation of response to drug(GO:2001023)
0.3 1.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 4.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.2 GO:0019075 virus maturation(GO:0019075)
0.2 1.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 1.0 GO:2000491 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 0.9 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.2 0.5 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 1.8 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 1.1 GO:0045349 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.2 0.9 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.9 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 0.6 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 7.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 1.0 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 0.8 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 1.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.6 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 2.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 9.7 GO:0032608 interferon-beta production(GO:0032608)
0.2 3.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 4.5 GO:0072189 ureter development(GO:0072189)
0.2 1.0 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 1.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 2.0 GO:0016584 nucleosome positioning(GO:0016584)
0.2 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 0.6 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.2 0.5 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.9 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.9 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.7 GO:0003014 renal system process(GO:0003014)
0.1 1.3 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 3.4 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.7 GO:0034127 detection of lipopolysaccharide(GO:0032497) regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 1.9 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 1.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 6.4 GO:0006536 glutamate metabolic process(GO:0006536)
0.1 2.4 GO:0006968 cellular defense response(GO:0006968)
0.1 0.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 1.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.6 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.9 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 1.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 1.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.4 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.8 GO:0033590 response to cobalamin(GO:0033590)
0.1 3.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.7 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.5 GO:0015692 lead ion transport(GO:0015692)
0.1 0.3 GO:0046968 peptide antigen transport(GO:0046968)
0.1 0.6 GO:0022604 regulation of cell morphogenesis(GO:0022604)
0.1 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.4 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 2.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 3.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 2.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 2.7 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 4.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.7 GO:0015793 glycerol transport(GO:0015793)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.1 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.4 GO:0071220 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 1.0 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 0.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.3 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.7 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.5 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.1 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 10.3 GO:0007286 spermatid development(GO:0007286)
0.1 0.2 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 2.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 1.5 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.6 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 1.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:0021678 third ventricle development(GO:0021678)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0002758 innate immune response-activating signal transduction(GO:0002758)
0.1 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.6 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 2.0 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 2.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.8 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 1.0 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 1.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.7 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0085020 protein K6-linked ubiquitination(GO:0085020) regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 0.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 1.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.9 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.5 GO:0097104 postsynaptic membrane assembly(GO:0097104)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343) behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.3 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.3 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.3 GO:0002778 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:0060926 cardiac pacemaker cell development(GO:0060926) sinoatrial node cell development(GO:0060931)
0.0 1.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 1.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.4 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:1902952 regulation of postsynaptic density protein 95 clustering(GO:1902897) positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0021853 cerebral cortex tangential migration(GO:0021800) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.8 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.4 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.5 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.8 GO:0009988 cell-cell recognition(GO:0009988)
0.0 1.0 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.6 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 2.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 1.7 GO:0007586 digestion(GO:0007586)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:0003341 cilium movement(GO:0003341)
0.0 0.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 30.0 GO:1990111 spermatoproteasome complex(GO:1990111)
3.3 19.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.8 5.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.7 3.3 GO:0005879 axonemal microtubule(GO:0005879)
0.6 1.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.6 4.1 GO:0042825 TAP complex(GO:0042825)
0.5 3.3 GO:0008537 proteasome activator complex(GO:0008537)
0.5 4.2 GO:0030870 Mre11 complex(GO:0030870)
0.4 1.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 1.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 3.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 1.2 GO:0031213 RSF complex(GO:0031213)
0.3 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.3 27.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 0.8 GO:0072534 perineuronal net(GO:0072534)
0.3 3.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.6 GO:0097179 protease inhibitor complex(GO:0097179)
0.3 4.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 3.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 2.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.6 GO:0001534 radial spoke(GO:0001534)
0.2 2.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 11.5 GO:0016235 aggresome(GO:0016235)
0.1 10.4 GO:0005643 nuclear pore(GO:0005643)
0.1 0.3 GO:0000785 chromatin(GO:0000785)
0.1 0.7 GO:0046696 lipopolysaccharide receptor compl