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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRF7

Z-value: 0.83

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Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
IRF7
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_6157280.019.4e-01Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_39770803 4.18 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr1_-_207119738 2.44 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr16_-_21289627 2.40 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr4_+_70861647 2.25 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chr6_+_32821924 1.97 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr6_-_29527702 1.96 ENST00000377050.4
UBD
ubiquitin D
chr10_+_51549498 1.96 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr5_+_96212185 1.87 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr5_+_96211643 1.87 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr1_+_79115503 1.84 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr7_+_106685079 1.74 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_+_948803 1.74 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr12_-_91574142 1.67 ENST00000547937.1
DCN
decorin
chr12_-_10282836 1.47 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr9_-_32526299 1.39 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr10_-_21435488 1.36 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113
chromosome 10 open reading frame 113
chr11_+_27062272 1.33 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_-_16921601 1.32 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3
anterior gradient 3
chr7_+_80275621 1.31 ENST00000426978.1
ENST00000432207.1
CD36
CD36 molecule (thrombospondin receptor)
chr4_-_100356844 1.29 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_46889694 1.29 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116
G protein-coupled receptor 116
chr12_+_6561190 1.27 ENST00000544021.1
ENST00000266556.7
TAPBPL
TAP binding protein-like
chr4_-_169239921 1.23 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr9_-_75567962 1.21 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_+_26036093 1.15 ENST00000374329.1
MAN1C1
mannosidase, alpha, class 1C, member 1
chr12_+_102091400 1.15 ENST00000229266.3
ENST00000549872.1
CHPT1
choline phosphotransferase 1
chr9_-_32526184 1.13 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr12_-_10282681 1.10 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr12_-_10282742 1.10 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr10_+_91061712 1.06 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chrX_-_71526741 0.94 ENST00000454225.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr4_-_100356551 0.92 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_+_41614909 0.92 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr10_-_1246317 0.90 ENST00000381305.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr12_-_10324716 0.90 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr1_-_108743471 0.88 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr13_-_86373536 0.87 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr14_-_81408063 0.83 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr14_-_54420133 0.82 ENST00000559501.1
ENST00000558984.1
BMP4
bone morphogenetic protein 4
chr10_+_91152303 0.82 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr5_+_140254884 0.80 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr1_-_150738261 0.79 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr17_+_53343577 0.79 ENST00000573945.1
HLF
hepatic leukemia factor
chr7_+_80231466 0.77 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr7_+_5919458 0.77 ENST00000416608.1
OCM
oncomodulin
chr4_-_138453559 0.77 ENST00000511115.1
PCDH18
protocadherin 18
chr7_-_122526799 0.76 ENST00000334010.7
ENST00000313070.7
CADPS2
Ca++-dependent secretion activator 2
chr17_-_46623441 0.76 ENST00000330070.4
HOXB2
homeobox B2
chr2_-_231084820 0.73 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr5_+_140261703 0.73 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr12_-_91573132 0.72 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr2_-_231084617 0.71 ENST00000409815.2
SP110
SP110 nuclear body protein
chr11_-_57335280 0.71 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr17_+_4643337 0.70 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr6_+_26365443 0.70 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr6_+_26402465 0.69 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr9_+_74764340 0.68 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr20_-_25038804 0.68 ENST00000323482.4
ACSS1
acyl-CoA synthetase short-chain family member 1
chrX_+_9431324 0.67 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr2_-_231084659 0.66 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr8_+_143808605 0.66 ENST00000336138.3
THEM6
thioesterase superfamily member 6
chr5_+_156696362 0.66 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr9_-_21995249 0.65 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr6_-_32821599 0.65 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_-_61495760 0.65 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr17_-_4643114 0.65 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr19_-_17516449 0.64 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr12_-_92536433 0.64 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr17_-_39165366 0.63 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr6_+_26440700 0.63 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr16_+_19179549 0.63 ENST00000355377.2
ENST00000568115.1
SYT17
synaptotagmin XVII
chrX_+_72667090 0.63 ENST00000373514.2
CDX4
caudal type homeobox 4
chr2_-_37899323 0.62 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr6_+_131958436 0.62 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr10_+_91092241 0.61 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr4_-_25865159 0.61 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr11_-_111794446 0.60 ENST00000527950.1
CRYAB
crystallin, alpha B
chr22_-_36556821 0.60 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr1_-_227505289 0.59 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr14_-_23288930 0.59 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_91572278 0.58 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr12_+_113344582 0.58 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_-_38806404 0.58 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr6_+_26402517 0.58 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr17_+_4643300 0.57 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr6_-_154751629 0.57 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr19_-_53466095 0.56 ENST00000391786.2
ENST00000434371.2
ENST00000357666.4
ENST00000438970.2
ENST00000270457.4
ENST00000535506.1
ENST00000444460.2
ENST00000457013.2
ZNF816
zinc finger protein 816
chr5_-_35938674 0.56 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr20_+_48884002 0.55 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr9_-_21995300 0.55 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr10_-_1246300 0.55 ENST00000381310.3
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr20_-_46415341 0.55 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr11_+_63304273 0.55 ENST00000439013.2
ENST00000255688.3
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr5_-_96143602 0.55 ENST00000443439.2
ENST00000503921.1
ENST00000508227.1
ENST00000507154.1
ERAP1
endoplasmic reticulum aminopeptidase 1
chr12_-_51402984 0.54 ENST00000545993.2
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr12_+_7167980 0.53 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr2_+_204801471 0.53 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr3_-_141747950 0.53 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_7005785 0.53 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_-_190446759 0.52 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr10_+_91087651 0.52 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr12_+_11802753 0.52 ENST00000396373.4
ETV6
ets variant 6
chr12_+_25205446 0.52 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr17_+_41158742 0.51 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr12_-_91576561 0.51 ENST00000547568.2
ENST00000552962.1
DCN
decorin
chr2_+_102721023 0.50 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chrX_+_51486481 0.50 ENST00000340438.4
GSPT2
G1 to S phase transition 2
chr14_+_91581011 0.50 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr1_+_79086088 0.50 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr14_-_70883708 0.49 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr1_-_227505826 0.49 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr1_-_104239076 0.49 ENST00000370080.3
AMY1B
amylase, alpha 1B (salivary)
chr5_-_146461027 0.49 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr14_+_91580708 0.49 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chrX_+_9217932 0.48 ENST00000432442.1
GS1-519E5.1
GS1-519E5.1
chr12_-_51422017 0.48 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr11_-_2906979 0.47 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr20_-_46415297 0.47 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr6_+_20534672 0.46 ENST00000274695.4
ENST00000378624.4
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr12_-_91576750 0.46 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN
decorin
chr3_-_121740969 0.46 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr13_-_43566301 0.46 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr6_+_147527103 0.46 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr15_-_89764929 0.46 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr12_+_25205568 0.45 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr14_+_91580777 0.45 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr17_+_6659153 0.45 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr10_+_91174314 0.45 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr8_-_23540402 0.45 ENST00000523261.1
ENST00000380871.4
NKX3-1
NK3 homeobox 1
chr11_+_46402482 0.45 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr19_+_13134772 0.44 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_151483855 0.43 ENST00000427934.2
ENST00000271636.7
CGN
cingulin
chr16_-_67970990 0.43 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_25205666 0.43 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr3_+_187086120 0.42 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr11_+_46402583 0.42 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr16_-_4850471 0.42 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi homolog (Drosophila)
chr3_-_49851313 0.42 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr17_+_68100989 0.42 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_-_47735918 0.42 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr16_-_69385681 0.41 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr12_-_7245125 0.41 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr14_-_67981916 0.41 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chrX_+_80457442 0.41 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr11_+_71710648 0.41 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr10_+_94608245 0.40 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr5_+_140501581 0.40 ENST00000194152.1
PCDHB4
protocadherin beta 4
chr11_+_71710973 0.40 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr1_+_156338993 0.40 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr12_-_59314246 0.40 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr4_-_76944621 0.40 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr3_-_187455680 0.39 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr6_-_711395 0.39 ENST00000606285.1
RP11-532F6.3
RP11-532F6.3
chr9_-_20622478 0.39 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr9_-_33264676 0.39 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr17_-_40346477 0.39 ENST00000593209.1
ENST00000587427.1
ENST00000588352.1
ENST00000414034.3
ENST00000590249.1
GHDC
GH3 domain containing
chr22_-_36635684 0.39 ENST00000358502.5
APOL2
apolipoprotein L, 2
chrX_+_44732757 0.39 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A
lysine (K)-specific demethylase 6A
chr16_-_4852915 0.38 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chrX_+_135388147 0.38 ENST00000394141.1
GPR112
G protein-coupled receptor 112
chr12_+_102271129 0.38 ENST00000258534.8
DRAM1
DNA-damage regulated autophagy modulator 1
chr7_-_122526499 0.38 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr11_+_46402297 0.38 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr2_-_97405775 0.38 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr3_+_113251143 0.38 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr9_-_33264557 0.38 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr10_+_114169299 0.37 ENST00000369410.3
ACSL5
acyl-CoA synthetase long-chain family member 5
chr3_+_122399444 0.37 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr1_-_157014865 0.37 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr8_-_17752996 0.37 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr3_-_194393206 0.37 ENST00000265245.5
LSG1
large 60S subunit nuclear export GTPase 1
chr13_-_103719196 0.37 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr1_+_211500129 0.37 ENST00000427925.2
ENST00000261464.5
TRAF5
TNF receptor-associated factor 5
chr20_-_47894569 0.36 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
ZNFX1
zinc finger, NFX1-type containing 1
chr10_+_123923205 0.36 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr1_+_211499957 0.36 ENST00000336184.2
TRAF5
TNF receptor-associated factor 5
chr17_-_40264692 0.36 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr7_-_92777606 0.36 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr6_-_160147925 0.36 ENST00000535561.1
SOD2
superoxide dismutase 2, mitochondrial
chr12_-_81763127 0.36 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr11_-_63330842 0.35 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr6_-_29324054 0.35 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr17_-_76975925 0.35 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr10_-_52383644 0.35 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr15_+_96875657 0.35 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_+_134331550 0.35 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM
2,3-bisphosphoglycerate mutase
chr2_-_152589670 0.35 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr2_+_99771418 0.35 ENST00000393473.2
ENST00000393477.3
ENST00000393474.3
ENST00000340066.1
ENST00000393471.2
ENST00000449211.1
ENST00000434566.1
ENST00000410042.1
LIPT1
MRPL30
lipoyltransferase 1
39S ribosomal protein L30, mitochondrial
chr10_+_94590910 0.34 ENST00000371547.4
EXOC6
exocyst complex component 6
chr7_+_121513143 0.34 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr6_-_33282163 0.34 ENST00000434618.2
ENST00000456592.2
TAPBP
TAP binding protein (tapasin)
chr7_-_16505440 0.34 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr1_+_61330931 0.34 ENST00000371191.1
NFIA
nuclear factor I/A
chr5_+_121297650 0.34 ENST00000339397.4
SRFBP1
serum response factor binding protein 1
chrX_+_77154935 0.33 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr1_-_182361327 0.33 ENST00000331872.6
ENST00000311223.5
GLUL
glutamate-ammonia ligase
chr13_-_33002151 0.33 ENST00000495479.1
ENST00000343281.4
ENST00000464470.1
ENST00000380139.4
ENST00000380133.2
N4BP2L1
NEDD4 binding protein 2-like 1
chr3_+_29322437 0.33 ENST00000434693.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr2_-_191878162 0.33 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr15_+_45021183 0.33 ENST00000559390.1
TRIM69
tripartite motif containing 69

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0036269 swimming behavior(GO:0036269)
0.7 2.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.7 2.8 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.5 2.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 1.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4 2.0 GO:0070842 aggresome assembly(GO:0070842)
0.3 1.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 1.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 0.9 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.3 2.1 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 3.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 2.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.7 GO:0071105 response to interleukin-11(GO:0071105)
0.3 4.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 0.8 GO:0048391 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.3 0.8 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 1.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 0.8 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 1.5 GO:0030421 defecation(GO:0030421)
0.2 1.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 0.6 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.2 0.6 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 1.0 GO:0015692 lead ion transport(GO:0015692)
0.2 0.8 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 0.6 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 0.7 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 0.5 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 3.7 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.2 2.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.7 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.2 2.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 0.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.6 GO:0009956 radial pattern formation(GO:0009956)
0.1 2.2 GO:0046541 saliva secretion(GO:0046541)
0.1 0.9 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.9 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.5 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.1 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 1.2 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.2 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) meiotic recombination checkpoint(GO:0051598)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 2.0 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.3 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.4 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.4 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 1.1 GO:0015866 ADP transport(GO:0015866)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0021546 rhombomere development(GO:0021546)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0003133 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 1.0 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.0 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.0 0.5 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 1.7 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0014897 physiological muscle hypertrophy(GO:0003298) cardiac muscle hypertrophy(GO:0003300) physiological cardiac muscle hypertrophy(GO:0003301) striated muscle hypertrophy(GO:0014897) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 3.6 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0072716 response to actinomycin D(GO:0072716)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.2 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.0 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.5 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.1 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.8 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 3.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 4.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.0 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 0.8 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.8 GO:0042825 TAP complex(GO:0042825)
0.1 1.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.3 GO:0031213 RSF complex(GO:0031213)
0.1 0.2 GO:0036029 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.8 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 0.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 4.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 2.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.5 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.5 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.7 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.7 2.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.6 2.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.6 2.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 1.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.3 1.7 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.3 2.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 2.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 1.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 1.0 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 1.4 GO:0046979 TAP2 binding(GO:0046979)
0.2 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 3.7 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 0.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.6 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 1.7 GO:0031386 protein tag(GO:0031386)
0.1 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.7 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 2.0 GO:0070628 proteasome binding(GO:0070628)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.4 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.1 0.4 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 4.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 4.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.9 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0019237 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 4.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 4.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 5.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis