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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRF9

Z-value: 0.95

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Transcription factors associated with IRF9

Gene Symbol Gene ID Gene Info
IRF9
ENSG00000213928.4 interferon regulatory factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF9hg19_v2_chr14_+_24630465_246305310.077.1e-01Click!

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_42733870 6.98 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr2_-_7005785 4.82 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr9_-_32526184 4.49 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_+_79115503 4.41 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr17_+_6659153 4.32 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr1_-_207119738 4.27 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr21_+_42798094 3.84 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr1_-_150738261 3.57 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr19_-_17516449 3.07 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr8_+_39770803 2.99 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr12_-_121477039 2.60 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr1_+_79086088 2.50 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr9_-_32526299 2.50 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_46889694 2.24 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
GPR116
G protein-coupled receptor 116
chr12_-_121476959 2.23 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr9_+_74764340 2.10 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr11_-_86383157 2.02 ENST00000393324.3
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr1_+_948803 1.87 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr4_-_169239921 1.85 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr7_+_100728720 1.78 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr11_-_86383650 1.69 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr6_-_31324943 1.68 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr9_+_74764278 1.53 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr11_-_57335280 1.52 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr10_+_91092241 1.50 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr14_-_67981916 1.44 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr3_+_187086120 1.40 ENST00000259030.2
RTP4
receptor (chemosensory) transporter protein 4
chr2_-_55920952 1.39 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr12_-_121476750 1.26 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr3_-_46037299 1.17 ENST00000296137.2
FYCO1
FYVE and coiled-coil domain containing 1
chr4_-_75719896 1.10 ENST00000395743.3
BTC
betacellulin
chr19_-_12807395 1.08 ENST00000587955.1
FBXW9
F-box and WD repeat domain containing 9
chr10_+_91061712 0.99 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr17_-_40264692 0.98 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr6_+_126240442 0.93 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr10_+_91174314 0.91 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr2_-_152146385 0.91 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr14_-_67981870 0.87 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr9_-_33264557 0.86 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr19_-_12807422 0.82 ENST00000380339.3
ENST00000544494.1
ENST00000393261.3
FBXW9
F-box and WD repeat domain containing 9
chr1_+_241695424 0.81 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_+_7017796 0.80 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr3_-_121379739 0.80 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr22_+_18632666 0.78 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr7_+_134832808 0.75 ENST00000275767.3
TMEM140
transmembrane protein 140
chr9_-_33264676 0.74 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr1_+_236687881 0.69 ENST00000526634.1
LGALS8
lectin, galactoside-binding, soluble, 8
chr2_+_205410516 0.67 ENST00000406610.2
ENST00000462231.1
PARD3B
par-3 family cell polarity regulator beta
chr6_+_6588902 0.64 ENST00000230568.4
LY86
lymphocyte antigen 86
chr12_-_56753858 0.64 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr3_-_146262637 0.63 ENST00000472349.1
ENST00000342435.4
PLSCR1
phospholipid scramblase 1
chr11_-_4414880 0.61 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr1_-_154580616 0.60 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr8_-_27941380 0.59 ENST00000413272.2
ENST00000341513.6
NUGGC
nuclear GTPase, germinal center associated
chr19_+_17516531 0.59 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
CTD-2521M24.9
chr6_+_37400974 0.59 ENST00000455891.1
ENST00000373451.4
CMTR1
cap methyltransferase 1
chr2_+_163175394 0.57 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr4_-_76944621 0.55 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_-_33282163 0.55 ENST00000434618.2
ENST00000456592.2
TAPBP
TAP binding protein (tapasin)
chr5_-_137911049 0.53 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr3_-_146262293 0.51 ENST00000448205.1
PLSCR1
phospholipid scramblase 1
chr7_-_105332084 0.51 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr3_-_146262428 0.51 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr3_+_122399444 0.50 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr9_+_70971815 0.50 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr2_-_220252603 0.48 ENST00000322176.7
ENST00000273075.4
DNPEP
aspartyl aminopeptidase
chr3_-_146262352 0.48 ENST00000462666.1
PLSCR1
phospholipid scramblase 1
chr9_-_21995249 0.47 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr9_-_21995300 0.45 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr19_+_10196981 0.44 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr17_+_38296576 0.44 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr4_+_146402925 0.44 ENST00000302085.4
SMAD1
SMAD family member 1
chr13_-_43566301 0.41 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr3_-_146262365 0.39 ENST00000448787.2
PLSCR1
phospholipid scramblase 1
chr3_-_142166846 0.36 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr12_+_113344582 0.33 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_163175133 0.31 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr3_-_146262488 0.24 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr16_+_28875126 0.24 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr6_-_8102714 0.23 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr3_-_141747439 0.23 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_-_33281979 0.23 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr6_-_33282024 0.23 ENST00000475304.1
ENST00000489157.1
TAPBP
TAP binding protein (tapasin)
chr9_+_102668915 0.21 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr15_+_45003675 0.15 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr1_+_162602244 0.13 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr1_+_241695670 0.12 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr18_-_67624160 0.09 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr6_-_82462425 0.09 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr3_-_141747459 0.08 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_-_95297534 0.08 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr17_+_78234625 0.08 ENST00000508628.2
ENST00000582970.1
ENST00000456466.1
ENST00000319921.4
RNF213
ring finger protein 213
chr10_+_115439282 0.07 ENST00000369321.2
ENST00000345633.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr2_-_152118352 0.06 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr10_+_115439630 0.06 ENST00000369318.3
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr10_+_115439699 0.06 ENST00000369315.1
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr15_+_74287035 0.06 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
PML
promyelocytic leukemia
chr1_-_182558374 0.05 ENST00000367559.3
ENST00000539397.1
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr6_-_110736742 0.05 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chr16_-_15736881 0.05 ENST00000540441.2
KIAA0430
KIAA0430
chr17_-_4167142 0.04 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr4_-_100140331 0.03 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr1_+_110993795 0.03 ENST00000271331.3
PROK1
prokineticin 1
chr20_+_61436146 0.02 ENST00000290291.6
OGFR
opioid growth factor receptor
chr10_-_7513904 0.01 ENST00000420395.1
RP5-1031D4.2
RP5-1031D4.2
chr3_-_27764190 0.01 ENST00000537516.1
EOMES
eomesodermin
chr13_+_50070077 0.00 ENST00000378319.3
ENST00000426879.1
PHF11
PHD finger protein 11
chr15_-_26108355 0.00 ENST00000356865.6
ATP10A
ATPase, class V, type 10A

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.6 4.8 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
1.0 3.1 GO:1901253 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
1.0 10.8 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.9 4.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.7 3.0 GO:0036269 swimming behavior(GO:0036269)
0.7 3.6 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.7 2.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.5 1.4 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.4 3.7 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 3.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.0 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.3 2.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 0.8 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 0.6 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 2.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 1.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.9 GO:0045354 negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.2 0.6 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.7 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 4.3 GO:0035456 response to interferon-beta(GO:0035456)
0.1 3.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.6 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.9 GO:2000111 senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 5.5 GO:0034340 response to type I interferon(GO:0034340)
0.1 0.3 GO:0019075 virus maturation(GO:0019075)
0.1 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.5 GO:0010819 regulation of T cell chemotaxis(GO:0010819) positive regulation of cAMP-mediated signaling(GO:0043950) regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 1.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.7 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0036021 endolysosome lumen(GO:0036021)
0.5 3.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.4 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 7.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 6.7 GO:0005643 nuclear pore(GO:0005643)
0.0 7.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0009041 uridylate kinase activity(GO:0009041)
1.0 3.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.6 3.7 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.5 4.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.3 1.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 2.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.4 GO:0034046 poly(G) binding(GO:0034046)
0.2 1.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 2.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.7 GO:0031386 protein tag(GO:0031386)
0.1 1.0 GO:0046979 TAP2 binding(GO:0046979)
0.1 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 3.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 11.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.6 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 3.1 GO:0019239 deaminase activity(GO:0019239)
0.1 1.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 10.8 GO:0008017 microtubule binding(GO:0008017)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 4.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 6.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 23.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 3.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling