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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRX2

Z-value: 0.43

Motif logo

Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
ENSG00000170561.8 iroquois homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX2hg19_v2_chr5_-_2751762_2751784-0.115.5e-01Click!

Activity profile of IRX2 motif

Sorted Z-values of IRX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_112565703 1.10 ENST00000488794.1
CD200 receptor 1-like
chr16_+_82068830 1.02 ENST00000199936.4
hydroxysteroid (17-beta) dehydrogenase 2
chr10_-_28270795 0.87 ENST00000545014.1
armadillo repeat containing 4
chr22_-_36013368 0.87 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr5_+_36608422 0.84 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_88117683 0.81 ENST00000369562.4
UPF0704 protein C6orf165
chr19_+_13134772 0.78 ENST00000587760.1
ENST00000585575.1
nuclear factor I/X (CCAAT-binding transcription factor)
chr13_+_35516390 0.78 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
neurobeachin
chr14_+_75536280 0.74 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr14_+_75536335 0.68 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
zinc finger, C2HC-type containing 1C
chr4_-_70505358 0.63 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UDP glucuronosyltransferase 2 family, polypeptide A2
chrX_-_117119243 0.62 ENST00000539496.1
ENST00000469946.1
kelch-like family member 13
chr17_+_7761301 0.61 ENST00000332439.4
ENST00000570446.1
cytochrome b5 domain containing 1
chr10_+_134150835 0.61 ENST00000432555.2
leucine rich repeat containing 27
chr3_-_151102529 0.58 ENST00000302632.3
purinergic receptor P2Y, G-protein coupled, 12
chr4_+_69681710 0.56 ENST00000265403.7
ENST00000458688.2
UDP glucuronosyltransferase 2 family, polypeptide B10
chr11_+_103907308 0.56 ENST00000302259.3
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr17_+_7761013 0.56 ENST00000571846.1
cytochrome b5 domain containing 1
chr5_+_156696362 0.55 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr2_+_159651821 0.53 ENST00000309950.3
ENST00000409042.1
death associated protein-like 1
chr13_-_46679185 0.53 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr13_-_46679144 0.52 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr4_-_38806404 0.48 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
toll-like receptor 1
chr10_+_127661942 0.47 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr10_-_100027943 0.45 ENST00000260702.3
lysyl oxidase-like 4
chr8_+_94767072 0.41 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
transmembrane protein 67
chr17_+_56232494 0.40 ENST00000268912.5
olfactory receptor, family 4, subfamily D, member 1
chr10_+_70320413 0.40 ENST00000373644.4
tet methylcytosine dioxygenase 1
chr3_-_113160334 0.37 ENST00000393845.2
ENST00000295868.2
WD repeat domain 52
chr7_-_105332084 0.36 ENST00000472195.1
ataxin 7-like 1
chr15_-_45670924 0.36 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr12_-_112450915 0.35 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
transmembrane protein 116
chr3_-_167371740 0.35 ENST00000466760.1
ENST00000479765.1
WD repeat domain 49
chr4_+_83821835 0.34 ENST00000302236.5
THAP domain containing 9
chr6_-_53013620 0.33 ENST00000259803.7
glial cells missing homolog 1 (Drosophila)
chr11_+_6866883 0.33 ENST00000299454.4
ENST00000379831.2
olfactory receptor, family 10, subfamily A, member 5
chr5_+_147258266 0.30 ENST00000296694.4
secretoglobin, family 3A, member 2
chrX_-_21676442 0.30 ENST00000379499.2
kelch-like family member 34
chr3_-_114343768 0.29 ENST00000393785.2
zinc finger and BTB domain containing 20
chr1_-_54405773 0.28 ENST00000371376.1
heat shock protein family B (small), member 11
chr1_-_207095324 0.27 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr1_-_92371839 0.27 ENST00000370399.2
transforming growth factor, beta receptor III
chr2_+_133874577 0.26 ENST00000596384.1
HCG2006742; Protein LOC100996685
chr4_-_168155417 0.26 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr18_-_53070913 0.25 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr3_+_108541545 0.25 ENST00000295756.6
T cell receptor associated transmembrane adaptor 1
chr7_-_130598059 0.25 ENST00000432045.2
microRNA 29a
chrX_+_9431324 0.24 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr8_+_81397876 0.24 ENST00000430430.1
zinc finger and BTB domain containing 10
chr8_+_24151553 0.23 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr1_+_166958346 0.23 ENST00000367872.4
maelstrom spermatogenic transposon silencer
chr1_-_151148492 0.23 ENST00000295314.4
tropomodulin 4 (muscle)
chr2_-_233877912 0.23 ENST00000264051.3
neuronal guanine nucleotide exchange factor
chr10_+_46997926 0.22 ENST00000374314.4
G protein regulated inducer of neurite outgrowth 2
chr22_+_23046750 0.22 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr10_+_96522361 0.22 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr17_-_26127525 0.22 ENST00000313735.6
nitric oxide synthase 2, inducible
chr1_+_166958497 0.22 ENST00000367870.2
maelstrom spermatogenic transposon silencer
chr1_-_151148442 0.21 ENST00000441701.1
ENST00000416280.2
tropomodulin 4 (muscle)
chr15_-_20193370 0.21 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr4_+_189060573 0.20 ENST00000332517.3
tripartite motif family-like 1
chr16_-_4401258 0.20 ENST00000577031.1
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr22_+_29168652 0.19 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chr7_+_150065278 0.17 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr3_-_186262166 0.17 ENST00000307944.5
crystallin, gamma S
chr14_+_62462541 0.17 ENST00000430451.2
synaptotagmin XVI
chr12_+_40787194 0.16 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr14_+_50999744 0.16 ENST00000441560.2
atlastin GTPase 1
chr1_-_207095212 0.16 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr6_+_30908747 0.15 ENST00000462446.1
ENST00000304311.2
diffuse panbronchiolitis critical region 1
chr4_+_88896819 0.14 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr11_+_98891797 0.14 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
contactin 5
chr19_-_35719609 0.14 ENST00000324675.3
family with sequence similarity 187, member B
chr3_-_194072019 0.14 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chrX_-_24045303 0.13 ENST00000328046.8
kelch-like family member 15
chr11_-_110561721 0.12 ENST00000357139.3
Rho GTPase activating protein 20
chr17_+_44590076 0.12 ENST00000333412.3
leucine rich repeat containing 37, member A2
chr9_-_13175823 0.12 ENST00000545857.1
multiple PDZ domain protein
chrX_+_150869023 0.11 ENST00000448324.1
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chrX_-_118739835 0.11 ENST00000542113.1
ENST00000304449.5
NFKB repressing factor
chr10_+_90660832 0.11 ENST00000371924.1
STAM binding protein-like 1
chr14_-_75536182 0.11 ENST00000555463.1
acylphosphatase 1, erythrocyte (common) type
chrX_+_148855726 0.11 ENST00000370416.4
heat shock transcription factor family, X linked 1
chr19_-_38720294 0.11 ENST00000412732.1
ENST00000456296.1
D4, zinc and double PHD fingers family 1
chr3_-_58419537 0.10 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
pyruvate dehydrogenase (lipoamide) beta
chr5_-_94417314 0.10 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr3_-_11645925 0.10 ENST00000413604.1
vestigial like 4 (Drosophila)
chrX_-_148676974 0.10 ENST00000524178.1
heat shock transcription factor family, X linked 2
chr1_-_157811588 0.09 ENST00000368174.4
CD5 molecule-like
chr4_-_153332886 0.09 ENST00000603841.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_-_107770794 0.09 ENST00000205386.4
ENST00000418464.1
ENST00000388781.3
ENST00000388780.3
ENST00000414450.2
laminin, beta 4
chr15_-_44486632 0.09 ENST00000484674.1
FERM domain containing 5
chr17_-_27054952 0.09 ENST00000580518.1
TLC domain containing 1
chr11_+_77532233 0.09 ENST00000525409.1
adipogenesis associated, Mth938 domain containing
chr15_+_44580955 0.09 ENST00000345795.2
ENST00000360824.3
cancer susceptibility candidate 4
chr14_+_52327109 0.09 ENST00000335281.4
guanine nucleotide binding protein (G protein), gamma 2
chr2_-_3504587 0.08 ENST00000415131.1
acireductone dioxygenase 1
chr3_+_132843652 0.08 ENST00000508711.1
transmembrane protein 108
chr17_-_2614927 0.08 ENST00000435359.1
clustered mitochondria (cluA/CLU1) homolog
chr18_+_5748793 0.08 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
chr1_+_206317450 0.08 ENST00000358184.2
ENST00000361052.3
ENST00000360218.2
cathepsin E
chr1_-_238649319 0.07 ENST00000400946.2
long intergenic non-protein coding RNA 1139
chr6_-_27841289 0.07 ENST00000355981.2
histone cluster 1, H4l
chr2_-_46844242 0.07 ENST00000281382.6
phosphatidylinositol glycan anchor biosynthesis, class F
chr5_+_167913450 0.07 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chrX_-_100129320 0.07 ENST00000372966.3
NADPH oxidase 1
chr14_+_23790655 0.07 ENST00000397276.2
poly(A) binding protein, nuclear 1
chr1_+_204839959 0.06 ENST00000404076.1
neurofascin
chr19_-_38720354 0.06 ENST00000416611.1
D4, zinc and double PHD fingers family 1
chr4_+_119606523 0.06 ENST00000388822.5
ENST00000506780.1
ENST00000508801.1
methyltransferase like 14
chr6_+_13272904 0.06 ENST00000379335.3
ENST00000379329.1
phosphatase and actin regulator 1
chr12_+_66218212 0.06 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
high mobility group AT-hook 2
chr2_-_98280383 0.06 ENST00000289228.5
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr12_+_32655110 0.06 ENST00000546442.1
ENST00000583694.1
FYVE, RhoGEF and PH domain containing 4
chr7_-_33140498 0.06 ENST00000448915.1
retinitis pigmentosa 9 (autosomal dominant)
chr2_-_46844159 0.06 ENST00000474980.1
ENST00000306465.4
phosphatidylinositol glycan anchor biosynthesis, class F
chr10_+_102672712 0.05 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
family with sequence similarity 178, member A
chr9_-_35812236 0.05 ENST00000340291.2
sperm associated antigen 8
chr1_+_215747118 0.05 ENST00000448333.1
potassium channel tetramerization domain containing 3
chr12_-_112856623 0.05 ENST00000551291.2
ribosomal protein L6
chr11_-_118305921 0.04 ENST00000532619.1
RP11-770J1.4
chr2_-_70520539 0.04 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr10_+_1095416 0.04 ENST00000358220.1
WD repeat domain 37
chr8_-_124428569 0.04 ENST00000521903.1
ATPase family, AAA domain containing 2
chr2_-_109605663 0.04 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
ectodysplasin A receptor
chr9_+_35792151 0.04 ENST00000342694.2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr17_+_37856299 0.04 ENST00000269571.5
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr1_+_67673297 0.04 ENST00000425614.1
ENST00000395227.1
interleukin 23 receptor
chr4_+_159131630 0.04 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
transmembrane protein 144
chr20_+_56136136 0.04 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chrX_+_19373700 0.04 ENST00000379804.1
pyruvate dehydrogenase (lipoamide) alpha 1
chr4_-_80247162 0.03 ENST00000286794.4
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr8_-_86253888 0.03 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr3_+_31574189 0.03 ENST00000295770.2
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr8_+_40018977 0.03 ENST00000520487.1
RP11-470M17.2
chr8_+_67104323 0.03 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
long intergenic non-protein coding RNA 967
chr16_+_69373323 0.03 ENST00000254940.5
NIP7, nucleolar pre-rRNA processing protein
chr8_+_81397846 0.03 ENST00000379091.4
zinc finger and BTB domain containing 10
chr5_-_39364586 0.03 ENST00000263408.4
complement component 9
chr18_+_50278430 0.02 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
deleted in colorectal carcinoma
chr2_+_46844290 0.02 ENST00000238892.3
cysteine-rich PDZ-binding protein
chr13_+_28519343 0.02 ENST00000381026.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr12_+_53773944 0.02 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr17_+_74075263 0.02 ENST00000334586.5
ENST00000392503.2
zinc activated ligand-gated ion channel
chr20_-_31592113 0.02 ENST00000420875.1
ENST00000375519.2
ENST00000375523.3
ENST00000356173.3
Sad1 and UNC84 domain containing 5
chr12_-_91505608 0.02 ENST00000266718.4
lumican
chr1_+_29138654 0.02 ENST00000234961.2
opioid receptor, delta 1
chr16_+_21244986 0.01 ENST00000311620.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr1_+_113010056 0.01 ENST00000369686.5
wingless-type MMTV integration site family, member 2B
chr19_-_29704448 0.01 ENST00000304863.4
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr9_-_113100088 0.01 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
thioredoxin domain containing 8 (spermatozoa)
chr4_-_83821676 0.01 ENST00000355196.2
ENST00000507676.1
ENST00000506495.1
ENST00000507051.1
SEC31 homolog A (S. cerevisiae)
chr17_-_5322786 0.00 ENST00000225696.4
nucleoporin 88kDa
chr1_+_152691998 0.00 ENST00000368775.2
chromosome 1 open reading frame 68
chr19_+_3762645 0.00 ENST00000330133.4
mitochondrial ribosomal protein L54
chr4_+_187187337 0.00 ENST00000492972.2
coagulation factor XI
chr3_+_46616017 0.00 ENST00000542931.1
teratocarcinoma-derived growth factor 1
chr18_+_55018044 0.00 ENST00000324000.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_138721850 0.00 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 0.5 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.9 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284) positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.4 GO:0030849 autosome(GO:0030849)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics