Project

Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

Navigation
Downloads

Results for IRX2

Z-value: 0.43

Motif logo

logo of

Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.8 iroquois homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX2hg19_v2_chr5_-_2751762_2751784-0.115.5e-01Click!

Activity profile of IRX2 motif

Sorted Z-values of IRX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_112565703 1.10 ENST00000488794.1
CD200R1L
CD200 receptor 1-like
chr16_+_82068830 1.02 ENST00000199936.4
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr10_-_28270795 0.87 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr22_-_36013368 0.87 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr5_+_36608422 0.84 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_88117683 0.81 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr19_+_13134772 0.78 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr13_+_35516390 0.78 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr14_+_75536280 0.74 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr14_+_75536335 0.68 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr4_-_70505358 0.63 ENST00000457664.2
ENST00000604629.1
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chrX_-_117119243 0.62 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr17_+_7761301 0.61 ENST00000332439.4
ENST00000570446.1
CYB5D1
cytochrome b5 domain containing 1
chr10_+_134150835 0.61 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr3_-_151102529 0.58 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr4_+_69681710 0.56 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr11_+_103907308 0.56 ENST00000302259.3
DDI1
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr17_+_7761013 0.56 ENST00000571846.1
CYB5D1
cytochrome b5 domain containing 1
chr5_+_156696362 0.55 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_159651821 0.53 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr13_-_46679185 0.53 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr13_-_46679144 0.52 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr4_-_38806404 0.48 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr10_+_127661942 0.47 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr10_-_100027943 0.45 ENST00000260702.3
LOXL4
lysyl oxidase-like 4
chr8_+_94767072 0.41 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67
transmembrane protein 67
chr17_+_56232494 0.40 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr10_+_70320413 0.40 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr3_-_113160334 0.37 ENST00000393845.2
ENST00000295868.2
WDR52
WD repeat domain 52
chr7_-_105332084 0.36 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr15_-_45670924 0.36 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr12_-_112450915 0.35 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
TMEM116
transmembrane protein 116
chr3_-_167371740 0.35 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chr4_+_83821835 0.34 ENST00000302236.5
THAP9
THAP domain containing 9
chr6_-_53013620 0.33 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr11_+_6866883 0.33 ENST00000299454.4
ENST00000379831.2
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chr5_+_147258266 0.30 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chrX_-_21676442 0.30 ENST00000379499.2
KLHL34
kelch-like family member 34
chr3_-_114343768 0.29 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_54405773 0.28 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr1_-_207095324 0.27 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr1_-_92371839 0.27 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr2_+_133874577 0.26 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr4_-_168155417 0.26 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr18_-_53070913 0.25 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr3_+_108541545 0.25 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr7_-_130598059 0.25 ENST00000432045.2
MIR29B1
microRNA 29a
chrX_+_9431324 0.24 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr8_+_81397876 0.24 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr8_+_24151553 0.23 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr1_+_166958346 0.23 ENST00000367872.4
MAEL
maelstrom spermatogenic transposon silencer
chr1_-_151148492 0.23 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr2_-_233877912 0.23 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr10_+_46997926 0.22 ENST00000374314.4
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr22_+_23046750 0.22 ENST00000390307.2
IGLV3-22
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr10_+_96522361 0.22 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr17_-_26127525 0.22 ENST00000313735.6
NOS2
nitric oxide synthase 2, inducible
chr1_+_166958497 0.22 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr1_-_151148442 0.21 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr15_-_20193370 0.21 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr4_+_189060573 0.20 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr16_-_4401258 0.20 ENST00000577031.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr22_+_29168652 0.19 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr7_+_150065278 0.17 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr3_-_186262166 0.17 ENST00000307944.5
CRYGS
crystallin, gamma S
chr14_+_62462541 0.17 ENST00000430451.2
SYT16
synaptotagmin XVI
chr12_+_40787194 0.16 ENST00000425730.2
ENST00000454784.4
MUC19
mucin 19, oligomeric
chr14_+_50999744 0.16 ENST00000441560.2
ATL1
atlastin GTPase 1
chr1_-_207095212 0.16 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr6_+_30908747 0.15 ENST00000462446.1
ENST00000304311.2
DPCR1
diffuse panbronchiolitis critical region 1
chr4_+_88896819 0.14 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr11_+_98891797 0.14 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
CNTN5
contactin 5
chr19_-_35719609 0.14 ENST00000324675.3
FAM187B
family with sequence similarity 187, member B
chr3_-_194072019 0.14 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chrX_-_24045303 0.13 ENST00000328046.8
KLHL15
kelch-like family member 15
chr11_-_110561721 0.12 ENST00000357139.3
ARHGAP20
Rho GTPase activating protein 20
chr17_+_44590076 0.12 ENST00000333412.3
LRRC37A2
leucine rich repeat containing 37, member A2
chr9_-_13175823 0.12 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chrX_+_150869023 0.11 ENST00000448324.1
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chrX_-_118739835 0.11 ENST00000542113.1
ENST00000304449.5
NKRF
NFKB repressing factor
chr10_+_90660832 0.11 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr14_-_75536182 0.11 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chrX_+_148855726 0.11 ENST00000370416.4
HSFX1
heat shock transcription factor family, X linked 1
chr19_-_38720294 0.11 ENST00000412732.1
ENST00000456296.1
DPF1
D4, zinc and double PHD fingers family 1
chr3_-_58419537 0.10 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr5_-_94417314 0.10 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr3_-_11645925 0.10 ENST00000413604.1
VGLL4
vestigial like 4 (Drosophila)
chrX_-_148676974 0.10 ENST00000524178.1
HSFX2
heat shock transcription factor family, X linked 2
chr1_-_157811588 0.09 ENST00000368174.4
CD5L
CD5 molecule-like
chr4_-_153332886 0.09 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_-_107770794 0.09 ENST00000205386.4
ENST00000418464.1
ENST00000388781.3
ENST00000388780.3
ENST00000414450.2
LAMB4
laminin, beta 4
chr15_-_44486632 0.09 ENST00000484674.1
FRMD5
FERM domain containing 5
chr17_-_27054952 0.09 ENST00000580518.1
TLCD1
TLC domain containing 1
chr11_+_77532233 0.09 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr15_+_44580955 0.09 ENST00000345795.2
ENST00000360824.3
CASC4
cancer susceptibility candidate 4
chr14_+_52327109 0.09 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr2_-_3504587 0.08 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr3_+_132843652 0.08 ENST00000508711.1
TMEM108
transmembrane protein 108
chr17_-_2614927 0.08 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr18_+_5748793 0.08 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
RP11-945C19.1
chr1_+_206317450 0.08 ENST00000358184.2
ENST00000361052.3
ENST00000360218.2
CTSE
cathepsin E
chr1_-_238649319 0.07 ENST00000400946.2
RP11-371I1.2
long intergenic non-protein coding RNA 1139
chr6_-_27841289 0.07 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr2_-_46844242 0.07 ENST00000281382.6
PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
chr5_+_167913450 0.07 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chrX_-_100129320 0.07 ENST00000372966.3
NOX1
NADPH oxidase 1
chr14_+_23790655 0.07 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr1_+_204839959 0.06 ENST00000404076.1
NFASC
neurofascin
chr19_-_38720354 0.06 ENST00000416611.1
DPF1
D4, zinc and double PHD fingers family 1
chr4_+_119606523 0.06 ENST00000388822.5
ENST00000506780.1
ENST00000508801.1
METTL14
methyltransferase like 14
chr6_+_13272904 0.06 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr12_+_66218212 0.06 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr2_-_98280383 0.06 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr12_+_32655110 0.06 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_-_33140498 0.06 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr2_-_46844159 0.06 ENST00000474980.1
ENST00000306465.4
PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
chr10_+_102672712 0.05 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr9_-_35812236 0.05 ENST00000340291.2
SPAG8
sperm associated antigen 8
chr1_+_215747118 0.05 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr12_-_112856623 0.05 ENST00000551291.2
RPL6
ribosomal protein L6
chr11_-_118305921 0.04 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr2_-_70520539 0.04 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr10_+_1095416 0.04 ENST00000358220.1
WDR37
WD repeat domain 37
chr8_-_124428569 0.04 ENST00000521903.1
ATAD2
ATPase family, AAA domain containing 2
chr2_-_109605663 0.04 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr9_+_35792151 0.04 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr17_+_37856299 0.04 ENST00000269571.5
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr1_+_67673297 0.04 ENST00000425614.1
ENST00000395227.1
IL23R
interleukin 23 receptor
chr4_+_159131630 0.04 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr20_+_56136136 0.04 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chrX_+_19373700 0.04 ENST00000379804.1
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr4_-_80247162 0.03 ENST00000286794.4
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr8_-_86253888 0.03 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr3_+_31574189 0.03 ENST00000295770.2
STT3B
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr8_+_40018977 0.03 ENST00000520487.1
RP11-470M17.2
RP11-470M17.2
chr8_+_67104323 0.03 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
LINC00967
long intergenic non-protein coding RNA 967
chr16_+_69373323 0.03 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr8_+_81397846 0.03 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr5_-_39364586 0.03 ENST00000263408.4
C9
complement component 9
chr18_+_50278430 0.02 ENST00000578080.1
ENST00000582875.1
ENST00000412726.1
DCC
deleted in colorectal carcinoma
chr2_+_46844290 0.02 ENST00000238892.3
CRIPT
cysteine-rich PDZ-binding protein
chr13_+_28519343 0.02 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr12_+_53773944 0.02 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr17_+_74075263 0.02 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr20_-_31592113 0.02 ENST00000420875.1
ENST00000375519.2
ENST00000375523.3
ENST00000356173.3
SUN5
Sad1 and UNC84 domain containing 5
chr12_-_91505608 0.02 ENST00000266718.4
LUM
lumican
chr1_+_29138654 0.02 ENST00000234961.2
OPRD1
opioid receptor, delta 1
chr16_+_21244986 0.01 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr1_+_113010056 0.01 ENST00000369686.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr19_-_29704448 0.01 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr9_-_113100088 0.01 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr4_-_83821676 0.01 ENST00000355196.2
ENST00000507676.1
ENST00000506495.1
ENST00000507051.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr17_-_5322786 0.00 ENST00000225696.4
NUP88
nucleoporin 88kDa
chr1_+_152691998 0.00 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr19_+_3762645 0.00 ENST00000330133.4
MRPL54
mitochondrial ribosomal protein L54
chr4_+_187187337 0.00 ENST00000492972.2
F11
coagulation factor XI
chr3_+_46616017 0.00 ENST00000542931.1
TDGF1
teratocarcinoma-derived growth factor 1
chr18_+_55018044 0.00 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_138721850 0.00 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 0.5 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.9 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284) positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.4 GO:0030849 autosome(GO:0030849)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics