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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for IRX5

Z-value: 0.50

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Transcription factors associated with IRX5

Gene Symbol Gene ID Gene Info
IRX5
ENSG00000176842.10 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX5hg19_v2_chr16_+_54964740_549647890.271.5e-01Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58329819 2.34 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr7_-_99573677 2.06 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr7_-_99573640 2.05 ENST00000411734.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr2_+_228735763 1.70 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr16_+_19467772 1.64 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr15_-_56757329 1.32 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr3_+_100354442 1.27 ENST00000475887.1
GPR128
G protein-coupled receptor 128
chr13_+_97928395 1.25 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr13_+_50589390 1.23 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr13_-_36429763 1.23 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr3_-_9994021 1.17 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr13_-_20080080 1.13 ENST00000400103.2
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr20_-_3762087 1.11 ENST00000379756.3
SPEF1
sperm flagellar 1
chr6_-_52705641 1.00 ENST00000370989.2
GSTA5
glutathione S-transferase alpha 5
chr11_+_6897856 0.96 ENST00000379829.2
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr4_+_69962185 0.88 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr7_-_138348969 0.87 ENST00000436657.1
SVOPL
SVOP-like
chr4_+_41361616 0.87 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr4_+_69962212 0.87 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr10_+_127661942 0.84 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr3_+_160473996 0.83 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr21_-_34185944 0.83 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr12_+_55248289 0.81 ENST00000308796.6
MUCL1
mucin-like 1
chr8_-_108510224 0.78 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr12_-_58329888 0.75 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr20_+_54933971 0.67 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr9_+_105757590 0.65 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr12_-_10282836 0.64 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr4_-_100356844 0.64 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_+_140175987 0.62 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr6_-_52774464 0.59 ENST00000370968.1
ENST00000211122.3
GSTA3
glutathione S-transferase alpha 3
chr8_+_120885949 0.57 ENST00000523492.1
ENST00000286234.5
DEPTOR
DEP domain containing MTOR-interacting protein
chr1_-_227505289 0.56 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr6_+_26217159 0.55 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr1_+_63989004 0.54 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr7_-_16844611 0.54 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr15_+_66585555 0.52 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr20_+_43990576 0.52 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr8_+_67976593 0.52 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr17_+_18380051 0.45 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr12_-_10282681 0.42 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr6_-_154677900 0.42 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr12_-_10282742 0.42 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr19_-_2740036 0.40 ENST00000586572.1
ENST00000269740.4
AC006538.4
SLC39A3
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr14_-_23624511 0.40 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr6_-_111804393 0.38 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr14_-_23623577 0.38 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr9_-_37465396 0.38 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr6_-_111804905 0.36 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr11_-_22647350 0.35 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr4_+_56212270 0.35 ENST00000264228.4
SRD5A3
steroid 5 alpha-reductase 3
chr8_-_17555164 0.35 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr8_+_27947746 0.35 ENST00000521015.1
ENST00000521570.1
ELP3
elongator acetyltransferase complex subunit 3
chr16_+_19535235 0.35 ENST00000565376.2
ENST00000396208.2
CCP110
centriolar coiled coil protein 110kDa
chr17_-_47723943 0.35 ENST00000510476.1
ENST00000503676.1
SPOP
speckle-type POZ protein
chr2_+_113299990 0.35 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr17_-_67264947 0.34 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr7_-_112430427 0.34 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
TMEM168
transmembrane protein 168
chr10_-_115904361 0.34 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr3_+_171561127 0.33 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr15_+_66585879 0.32 ENST00000319212.4
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr19_+_20959098 0.32 ENST00000360204.5
ENST00000594534.1
ZNF66
zinc finger protein 66
chr6_+_146920116 0.32 ENST00000367493.3
ADGB
androglobin
chr14_-_106845789 0.31 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr2_+_38177575 0.31 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr6_+_146920097 0.31 ENST00000397944.3
ENST00000522242.1
ADGB
androglobin
chr19_-_40596828 0.31 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
ZNF780A
zinc finger protein 780A
chr16_+_19535133 0.31 ENST00000396212.2
ENST00000381396.5
CCP110
centriolar coiled coil protein 110kDa
chr5_-_93447333 0.30 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr1_-_85870177 0.29 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr13_-_41768654 0.29 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr14_+_22293618 0.29 ENST00000390432.2
TRAV10
T cell receptor alpha variable 10
chr15_+_41057818 0.27 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr1_+_97188188 0.26 ENST00000541987.1
PTBP2
polypyrimidine tract binding protein 2
chr10_+_96698406 0.26 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr18_+_33709834 0.25 ENST00000358232.6
ENST00000351393.6
ENST00000442325.2
ENST00000423854.2
ENST00000350494.6
ENST00000542824.1
ELP2
elongator acetyltransferase complex subunit 2
chr7_-_92777606 0.25 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr4_+_76995855 0.24 ENST00000355810.4
ENST00000349321.3
ART3
ADP-ribosyltransferase 3
chr17_+_25958174 0.24 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr1_-_112106556 0.24 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr2_+_169757750 0.22 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr7_-_92855762 0.22 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr7_+_66386204 0.22 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chr3_-_3221358 0.22 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr12_-_102224704 0.22 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr11_+_60048053 0.22 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr14_+_56127989 0.21 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr5_-_13944652 0.21 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr12_+_56114189 0.21 ENST00000548082.1
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr8_+_125463048 0.21 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr12_-_88423164 0.21 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr19_+_50691437 0.20 ENST00000598205.1
MYH14
myosin, heavy chain 14, non-muscle
chr8_+_84824920 0.20 ENST00000523678.1
RP11-120I21.2
RP11-120I21.2
chr1_+_158969752 0.20 ENST00000566111.1
IFI16
interferon, gamma-inducible protein 16
chr12_+_71833550 0.20 ENST00000266674.5
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr9_+_42704004 0.20 ENST00000457288.1
CBWD7
COBW domain containing 7
chr8_-_12668962 0.19 ENST00000534827.1
RP11-252C15.1
RP11-252C15.1
chr3_-_52713729 0.19 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr21_-_34185989 0.19 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr4_-_75695366 0.19 ENST00000512743.1
BTC
betacellulin
chr19_-_54974894 0.19 ENST00000333834.4
LENG9
leukocyte receptor cluster (LRC) member 9
chr12_+_10365404 0.18 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr17_-_42327236 0.18 ENST00000399246.2
AC003102.1
AC003102.1
chr1_-_115124257 0.18 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr4_+_70146217 0.17 ENST00000335568.5
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr12_+_56114151 0.17 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr1_-_152086556 0.17 ENST00000368804.1
TCHH
trichohyalin
chr11_+_60048004 0.17 ENST00000532114.1
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr1_+_109256067 0.17 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr1_-_213020991 0.17 ENST00000332912.3
C1orf227
chromosome 1 open reading frame 227
chr10_+_118350522 0.16 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr11_-_118305921 0.16 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr16_+_48657361 0.16 ENST00000565072.1
RP11-42I10.1
RP11-42I10.1
chr9_-_113100088 0.15 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr3_+_173116225 0.15 ENST00000457714.1
NLGN1
neuroligin 1
chr1_+_196912902 0.15 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr4_+_185973026 0.15 ENST00000506338.1
ENST00000509017.1
RP11-386B13.3
RP11-386B13.3
chr6_+_29364416 0.15 ENST00000383555.2
OR12D2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr3_+_138066539 0.15 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr3_-_72897545 0.15 ENST00000325599.8
SHQ1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr13_+_24844819 0.14 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr10_+_118350468 0.14 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr1_-_7913089 0.14 ENST00000361696.5
UTS2
urotensin 2
chr1_+_15668240 0.13 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_-_145826450 0.13 ENST00000462900.2
GPR89A
G protein-coupled receptor 89A
chr15_+_49170083 0.13 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr1_-_21377383 0.12 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr10_+_90660832 0.12 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr19_-_23456996 0.12 ENST00000594653.1
RP11-15H20.7
RP11-15H20.7
chr4_+_113739244 0.11 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2
ankyrin 2, neuronal
chr17_+_58018269 0.11 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr13_+_76362974 0.11 ENST00000497947.2
LMO7
LIM domain 7
chr17_+_56232494 0.11 ENST00000268912.5
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr17_-_29641084 0.10 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chrX_-_33229636 0.10 ENST00000357033.4
DMD
dystrophin
chr2_-_40657397 0.10 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr8_-_116504448 0.10 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr3_+_186383741 0.10 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr14_+_73563735 0.10 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr16_+_56969284 0.10 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr15_+_25200108 0.09 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr11_+_59807748 0.09 ENST00000278855.2
ENST00000532905.1
PLAC1L
oocyte secreted protein 2
chr4_+_130017268 0.09 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr19_-_12992274 0.09 ENST00000592506.1
ENST00000222219.3
DNASE2
deoxyribonuclease II, lysosomal
chr12_-_127174806 0.09 ENST00000545853.1
ENST00000537478.1
RP11-407A16.3
RP11-407A16.3
chr18_+_22006580 0.09 ENST00000284202.4
IMPACT
impact RWD domain protein
chr3_-_168865522 0.09 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr20_+_10199468 0.08 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr9_-_21202204 0.08 ENST00000239347.3
IFNA7
interferon, alpha 7
chr4_-_103998439 0.08 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr19_-_12992244 0.08 ENST00000538460.1
DNASE2
deoxyribonuclease II, lysosomal
chr1_-_241683001 0.08 ENST00000366560.3
FH
fumarate hydratase
chr18_-_32924372 0.08 ENST00000261332.6
ENST00000399061.3
ZNF24
zinc finger protein 24
chr4_+_113558612 0.07 ENST00000505034.1
ENST00000324052.6
LARP7
La ribonucleoprotein domain family, member 7
chr19_-_50266580 0.07 ENST00000246801.3
TSKS
testis-specific serine kinase substrate
chr1_-_21377447 0.07 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr7_-_87856280 0.07 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr12_-_9360966 0.07 ENST00000261336.2
PZP
pregnancy-zone protein
chr1_+_26644441 0.07 ENST00000374213.2
CD52
CD52 molecule
chr21_-_43528548 0.07 ENST00000329015.2
C21orf128
chromosome 21 open reading frame 128
chr7_+_13141097 0.07 ENST00000411542.1
AC011288.2
AC011288.2
chr7_-_87856303 0.07 ENST00000394641.3
SRI
sorcin
chr4_-_22444733 0.07 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr13_+_96085847 0.06 ENST00000376873.3
CLDN10
claudin 10
chr2_+_113829895 0.06 ENST00000393197.2
IL1F10
interleukin 1 family, member 10 (theta)
chr15_+_65204075 0.06 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ANKDD1A
ankyrin repeat and death domain containing 1A
chr6_+_149887377 0.06 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr3_-_149470229 0.06 ENST00000473414.1
COMMD2
COMM domain containing 2
chr13_-_88323218 0.06 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr8_-_67976509 0.06 ENST00000518747.1
COPS5
COP9 signalosome subunit 5
chr1_+_196788887 0.06 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr14_-_23877474 0.05 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr10_-_35379524 0.05 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
CUL2
cullin 2
chr7_+_80267973 0.05 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr1_-_89488510 0.05 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr2_-_242041607 0.05 ENST00000434791.1
ENST00000401626.2
ENST00000439144.1
ENST00000406593.1
ENST00000495694.1
ENST00000407095.3
ENST00000391980.2
MTERFD2
MTERF domain containing 2
chr22_-_24096562 0.04 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chrX_+_108779004 0.04 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chrX_-_83757399 0.04 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr16_+_21689835 0.04 ENST00000286149.4
ENST00000388958.3
OTOA
otoancorin
chr21_-_43816052 0.04 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr18_-_69246167 0.04 ENST00000566582.1
RP11-510D19.1
RP11-510D19.1
chr11_+_114310237 0.03 ENST00000539119.1
REXO2
RNA exonuclease 2
chr3_+_155838337 0.03 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr1_+_53480598 0.03 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr1_-_116383738 0.03 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr15_-_44116873 0.03 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chr17_+_35732955 0.03 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr3_+_53528659 0.03 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr22_+_30821732 0.03 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr15_+_25200074 0.03 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr1_+_22778337 0.03 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr18_-_44702668 0.02 ENST00000256433.3
IER3IP1
immediate early response 3 interacting protein 1
chr14_+_51706886 0.02 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr1_+_145524891 0.02 ENST00000369304.3
ITGA10
integrin, alpha 10
chr16_-_20709066 0.02 ENST00000520010.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr19_-_22379753 0.02 ENST00000397121.2
ZNF676
zinc finger protein 676
chr19_-_44388116 0.02 ENST00000587539.1
ZNF404
zinc finger protein 404
chr3_-_127541194 0.01 ENST00000453507.2
MGLL
monoglyceride lipase
chr11_+_55029628 0.01 ENST00000417545.2
TRIM48
tripartite motif containing 48

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.7 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 4.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.4 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.2 GO:0032831 natural killer cell tolerance induction(GO:0002519) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.5 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 1.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 1.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 1.5 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 1.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.3 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.8 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:1900038 negative regulation of vascular permeability(GO:0043116) negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.9 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.8 GO:0016266 O-glycan processing(GO:0016266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 2.2 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2 4.1 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 0.6 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.3 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.0 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 1.5 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway