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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for ISL2

Z-value: 0.43

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Transcription factors associated with ISL2

Gene Symbol Gene ID Gene Info
ISL2
ENSG00000159556.5 ISL LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL2hg19_v2_chr15_+_76629064_766290730.193.1e-01Click!

Activity profile of ISL2 motif

Sorted Z-values of ISL2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_169013666 1.08 ENST00000359299.3
ANXA10
annexin A10
chr2_-_163008903 0.96 ENST00000418842.2
ENST00000375497.3
GCG
glucagon
chr13_-_20806440 0.94 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
GJB6
gap junction protein, beta 6, 30kDa
chr5_-_139726181 0.90 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr11_-_107729887 0.82 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr11_-_28129656 0.73 ENST00000263181.6
KIF18A
kinesin family member 18A
chr7_-_111032971 0.69 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr4_-_69111401 0.60 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr2_+_105050794 0.56 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr6_+_130339710 0.55 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_-_141747950 0.54 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chrX_+_96138907 0.54 ENST00000373040.3
RPA4
replication protein A4, 30kDa
chr3_+_172468505 0.54 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
ECT2
epithelial cell transforming sequence 2 oncogene
chr12_-_95945246 0.52 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr17_-_3496171 0.52 ENST00000399756.4
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr20_+_30102231 0.51 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chr3_+_172468472 0.49 ENST00000232458.5
ENST00000392692.3
ECT2
epithelial cell transforming sequence 2 oncogene
chr2_-_10587897 0.48 ENST00000405333.1
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr21_+_39644305 0.41 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr21_+_39644395 0.40 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_-_155776966 0.40 ENST00000159060.2
NOX3
NADPH oxidase 3
chr10_-_29923893 0.39 ENST00000355867.4
SVIL
supervillin
chr19_-_36001113 0.37 ENST00000434389.1
DMKN
dermokine
chr4_+_128702969 0.36 ENST00000508776.1
ENST00000439123.2
HSPA4L
heat shock 70kDa protein 4-like
chrX_-_21676442 0.35 ENST00000379499.2
KLHL34
kelch-like family member 34
chr6_+_151561085 0.35 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr3_+_169629354 0.34 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr8_-_125577940 0.32 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr17_-_64225508 0.31 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr10_-_95242044 0.31 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr10_-_95241951 0.31 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr2_-_136633940 0.31 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr19_-_3557570 0.29 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr20_-_50722183 0.29 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr11_-_5323226 0.28 ENST00000380224.1
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr10_-_115904361 0.28 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr4_+_95128748 0.27 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr18_-_64271316 0.25 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr13_-_46716969 0.25 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_67878917 0.25 ENST00000216446.4
PLEK2
pleckstrin 2
chr9_-_21482312 0.23 ENST00000448696.3
IFNE
interferon, epsilon
chr2_-_40680578 0.23 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_12946025 0.23 ENST00000235349.5
PRAMEF4
PRAME family member 4
chr6_+_42989344 0.22 ENST00000244496.5
RRP36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr11_+_28129795 0.21 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr14_-_106781017 0.21 ENST00000390612.2
IGHV4-28
immunoglobulin heavy variable 4-28
chr12_+_64798095 0.21 ENST00000332707.5
XPOT
exportin, tRNA
chr11_+_5410607 0.20 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chrX_-_100872911 0.20 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6
armadillo repeat containing, X-linked 6
chr14_-_53258314 0.20 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr3_+_139063372 0.19 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr7_+_13141097 0.19 ENST00000411542.1
AC011288.2
AC011288.2
chr12_-_110937351 0.16 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr3_+_63428752 0.16 ENST00000295894.5
SYNPR
synaptoporin
chr21_-_31859755 0.16 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr17_-_7307358 0.16 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_+_4402659 0.15 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr22_-_29107919 0.15 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr3_-_193096600 0.15 ENST00000446087.1
ENST00000342358.4
ATP13A5
ATPase type 13A5
chrX_-_77225135 0.15 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr10_-_50396425 0.15 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr10_-_5046042 0.15 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr11_+_113779704 0.14 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr1_+_63063152 0.14 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr5_+_57787254 0.13 ENST00000502276.1
ENST00000396776.2
ENST00000511930.1
GAPT
GRB2-binding adaptor protein, transmembrane
chr18_-_64271363 0.13 ENST00000262150.2
CDH19
cadherin 19, type 2
chrX_-_119077695 0.13 ENST00000371410.3
NKAP
NFKB activating protein
chr7_-_45151272 0.13 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
TBRG4
transforming growth factor beta regulator 4
chr14_+_45605157 0.12 ENST00000542564.2
FANCM
Fanconi anemia, complementation group M
chr1_+_13421176 0.12 ENST00000376152.1
PRAMEF9
PRAME family member 9
chr10_-_50396407 0.12 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr4_+_169418255 0.11 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr2_-_209010874 0.11 ENST00000260988.4
CRYGB
crystallin, gamma B
chr2_-_231860596 0.11 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr2_+_231921574 0.11 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr14_-_23058063 0.11 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1
defender against cell death 1
chr10_+_35484793 0.11 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr4_+_95128996 0.11 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr19_+_15852203 0.10 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr1_-_178840157 0.10 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr11_+_12132117 0.08 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr1_-_21377383 0.08 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr5_+_110427983 0.08 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr1_-_17766198 0.08 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr21_-_31864275 0.08 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr14_+_38677123 0.08 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr4_+_169418195 0.07 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr7_-_55930443 0.07 ENST00000388975.3
SEPT14
septin 14
chrX_+_102840408 0.07 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr6_+_26087509 0.07 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr15_-_83378638 0.07 ENST00000261722.3
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr1_+_77333117 0.07 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr12_+_26164645 0.07 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr12_+_104337515 0.07 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr5_+_40841276 0.07 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr17_-_33390667 0.07 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr1_-_95391315 0.06 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr14_-_74025625 0.06 ENST00000553558.1
ENST00000563329.1
ENST00000334988.2
ENST00000560393.1
HEATR4
HEAT repeat containing 4
chr11_-_92931098 0.06 ENST00000326402.4
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr2_+_234580525 0.06 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_+_123241908 0.06 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr9_+_35042205 0.06 ENST00000312292.5
ENST00000378745.3
C9orf131
chromosome 9 open reading frame 131
chr12_-_12715266 0.05 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr9_-_95166841 0.05 ENST00000262551.4
OGN
osteoglycin
chr2_+_234668894 0.05 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr12_+_4829507 0.05 ENST00000252318.2
GALNT8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr4_+_88532028 0.05 ENST00000282478.7
DSPP
dentin sialophosphoprotein
chr2_+_234580499 0.05 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr7_-_115670792 0.05 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr14_+_57671888 0.05 ENST00000391612.1
AL391152.1
AL391152.1
chr6_+_29555683 0.05 ENST00000383640.2
OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr3_+_136649311 0.05 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr19_+_29456034 0.04 ENST00000589921.1
LINC00906
long intergenic non-protein coding RNA 906
chr12_-_118628350 0.04 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr11_-_13517565 0.04 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr3_+_159943362 0.04 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr19_-_46234119 0.04 ENST00000317683.3
FBXO46
F-box protein 46
chr8_+_70404996 0.04 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr17_+_3118915 0.04 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr7_-_115670804 0.04 ENST00000320239.7
TFEC
transcription factor EC
chr19_-_51920952 0.04 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr8_-_121457608 0.04 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr4_-_122085469 0.04 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr17_-_10325261 0.04 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr1_+_99127225 0.04 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr9_+_12693336 0.04 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr4_-_90756769 0.03 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_-_37488834 0.03 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr6_+_31105426 0.03 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr3_-_20053741 0.03 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr13_-_45768841 0.03 ENST00000379108.1
KCTD4
potassium channel tetramerization domain containing 4
chr11_-_62609281 0.03 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr9_+_111624577 0.03 ENST00000333999.3
ACTL7A
actin-like 7A
chr3_-_127455200 0.03 ENST00000398101.3
MGLL
monoglyceride lipase
chr5_-_130500922 0.03 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1
histidine triad nucleotide binding protein 1
chr17_-_39156138 0.03 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr21_-_30445886 0.03 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
CCT8
chaperonin containing TCP1, subunit 8 (theta)
chr14_-_51027838 0.02 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr9_-_28670283 0.02 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr1_+_234765057 0.02 ENST00000429269.1
LINC00184
long intergenic non-protein coding RNA 184
chr17_-_48785216 0.02 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr8_-_30706608 0.02 ENST00000256246.2
TEX15
testis expressed 15
chrX_-_48931648 0.02 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr15_-_98417780 0.02 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr11_+_101983176 0.01 ENST00000524575.1
YAP1
Yes-associated protein 1
chr11_-_124190184 0.01 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr14_+_22670455 0.01 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr3_-_20227619 0.01 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
SGOL1
shugoshin-like 1 (S. pombe)
chr6_+_161123270 0.01 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr11_+_71544246 0.01 ENST00000328698.1
DEFB108B
defensin, beta 108B
chr2_-_217559517 0.00 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr15_+_58702742 0.00 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 0.7 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.9 GO:0051541 elastin metabolic process(GO:0051541)
0.2 0.5 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 1.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.4 GO:0048840 otolith development(GO:0048840)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.5 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0034392 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.9 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.0 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.0 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis