Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for JDP2
Z-value: 0.67
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Transcription factors associated with JDP2
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrY_+_15016725 Show fit | 3.11 |
ENST00000336079.3
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
|
| chr11_-_102668879 Show fit | 1.83 |
ENST00000315274.6
|
matrix metallopeptidase 1 (interstitial collagenase) |
|
| chr10_+_17270214 Show fit | 1.52 |
ENST00000544301.1
|
vimentin |
|
| chr12_+_7023735 Show fit | 1.36 |
ENST00000538763.1
ENST00000544774.1 ENST00000545045.2 |
enolase 2 (gamma, neuronal) |
|
| chr12_+_7023491 Show fit | 1.35 |
ENST00000541477.1
ENST00000229277.1 |
enolase 2 (gamma, neuronal) |
|
| chr9_-_124991124 Show fit | 1.19 |
ENST00000394319.4
ENST00000340587.3 |
LIM homeobox 6 |
|
| chr15_+_89182178 Show fit | 1.03 |
ENST00000559876.1
|
interferon stimulated exonuclease gene 20kDa |
|
| chr13_+_32838801 Show fit | 0.96 |
ENST00000542859.1
|
furry homolog (Drosophila) |
|
| chr15_+_89181974 Show fit | 0.84 |
ENST00000306072.5
|
interferon stimulated exonuclease gene 20kDa |
|
| chr10_+_127661942 Show fit | 0.83 |
ENST00000417114.1
ENST00000445510.1 ENST00000368691.1 |
fibronectin type III and ankyrin repeat domains 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of JDP2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | GO:0061621 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.0 | 2.6 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.5 | 2.4 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.1 | 2.3 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 2.3 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 2.0 | GO:0032461 | positive regulation of protein oligomerization(GO:0032461) |
| 0.1 | 1.4 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.1 | 1.4 | GO:0044351 | macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385) |
| 0.1 | 1.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.4 | 1.2 | GO:1903567 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 2.4 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 2.2 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 2.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 1.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.8 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.6 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.0 | 0.6 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 0.5 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.0 | 2.6 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.8 | 2.4 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.2 | 2.3 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.0 | 2.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 1.5 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.0 | 1.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 1.3 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 1.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 1.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.0 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 0.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.4 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 2.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 2.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 1.7 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.5 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 1.4 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 1.1 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.8 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 0.5 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |