Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for JUND
Z-value: 0.87
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Transcription factors associated with JUND
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| JUND | hg19_v2_chr19_-_18391708_18391739 | 0.16 | 4.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_102826434 Show fit | 2.87 |
ENST00000340273.4
ENST00000260302.3 |
matrix metallopeptidase 13 (collagenase 3) |
|
| chr5_-_140013275 Show fit | 2.31 |
ENST00000512545.1
ENST00000302014.6 ENST00000401743.2 |
CD14 molecule |
|
| chrY_+_15016725 Show fit | 2.11 |
ENST00000336079.3
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
|
| chr11_-_82708519 Show fit | 2.04 |
ENST00000534301.1
|
RAB30, member RAS oncogene family |
|
| chr15_-_74504597 Show fit | 1.95 |
ENST00000416286.3
|
stimulated by retinoic acid 6 |
|
| chr15_-_74504560 Show fit | 1.87 |
ENST00000449139.2
|
stimulated by retinoic acid 6 |
|
| chr22_-_37545972 Show fit | 1.51 |
ENST00000216223.5
|
interleukin 2 receptor, beta |
|
| chr12_-_95009837 Show fit | 1.35 |
ENST00000551457.1
|
transmembrane and coiled-coil domain family 3 |
|
| chr1_-_153348067 Show fit | 1.34 |
ENST00000368737.3
|
S100 calcium binding protein A12 |
|
| chr22_+_31488433 Show fit | 1.33 |
ENST00000455608.1
|
smoothelin |
Network of associatons between targets according to the STRING database.
First level regulatory network of JUND
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.8 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.6 | 3.0 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.1 | 2.5 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.6 | 2.3 | GO:0071727 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 0.2 | 2.2 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 2.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 2.0 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.2 | 1.5 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.0 | 1.3 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.2 | 1.2 | GO:0071724 | toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 2.5 | GO:0015030 | Cajal body(GO:0015030) |
| 0.5 | 2.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 2.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 1.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.3 | 1.1 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 0.0 | 0.8 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.0 | 0.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023) |
| 0.1 | 0.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.6 | GO:0008305 | integrin complex(GO:0008305) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.8 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 1.0 | 3.0 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.0 | 2.4 | GO:0005518 | collagen binding(GO:0005518) |
| 0.5 | 2.3 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.2 | 2.2 | GO:0102336 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 2.1 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.4 | 1.5 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 0.1 | 1.4 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.0 | 1.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 1.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 2.4 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.7 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 1.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.1 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.0 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 1.0 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.8 | PID PLK1 PATHWAY | PLK1 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.5 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 2.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 2.3 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.0 | 2.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 2.2 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 1.9 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 1.7 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 1.2 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 1.1 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.0 | 0.9 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |