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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for KLF1
Z-value: 1.26
Motif logo
Transcription factors associated with KLF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
KLF1
|
ENSG00000105610.4 | Kruppel like factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| KLF1 | hg19_v2_chr19_-_12997995_12998021 | -0.20 | 2.8e-01 | Click! |
Activity profile of KLF1 motif
Sorted Z-values of KLF1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_+_38071615 | 11.44 |
ENST00000215909.5
|
LGALS1
|
lectin, galactoside-binding, soluble, 1 |
| chr10_+_17272608 | 4.83 |
ENST00000421459.2
|
VIM
|
vimentin |
| chr11_-_62313090 | 4.29 |
ENST00000528508.1
ENST00000533365.1 |
AHNAK
|
AHNAK nucleoprotein |
| chr17_-_39553844 | 4.20 |
ENST00000251645.2
|
KRT31
|
keratin 31 |
| chr17_-_39526052 | 3.96 |
ENST00000251646.3
|
KRT33B
|
keratin 33B |
| chr2_-_26205340 | 3.96 |
ENST00000264712.3
|
KIF3C
|
kinesin family member 3C |
| chr19_-_36019123 | 3.85 |
ENST00000588674.1
ENST00000452271.2 ENST00000518157.1 |
SBSN
|
suprabasin |
| chr6_+_74405501 | 3.76 |
ENST00000437994.2
ENST00000422508.2 |
CD109
|
CD109 molecule |
| chr6_+_74405804 | 3.58 |
ENST00000287097.5
|
CD109
|
CD109 molecule |
| chr17_+_7210921 | 3.44 |
ENST00000573542.1
|
EIF5A
|
eukaryotic translation initiation factor 5A |
| chr16_-_30125177 | 3.25 |
ENST00000406256.3
|
GDPD3
|
glycerophosphodiester phosphodiesterase domain containing 3 |
| chr18_+_29027696 | 3.12 |
ENST00000257189.4
|
DSG3
|
desmoglein 3 |
| chr17_+_7210852 | 3.10 |
ENST00000576930.1
|
EIF5A
|
eukaryotic translation initiation factor 5A |
| chr6_-_131291572 | 3.07 |
ENST00000529208.1
|
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr1_-_27816556 | 3.06 |
ENST00000536657.1
|
WASF2
|
WAS protein family, member 2 |
| chr2_+_102314161 | 2.94 |
ENST00000425019.1
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4 |
| chr16_+_55600580 | 2.87 |
ENST00000457326.2
|
CAPNS2
|
calpain, small subunit 2 |
| chr17_-_40575535 | 2.85 |
ENST00000357037.5
|
PTRF
|
polymerase I and transcript release factor |
| chr5_+_147691979 | 2.84 |
ENST00000274565.4
|
SPINK7
|
serine peptidase inhibitor, Kazal type 7 (putative) |
| chr17_-_39507064 | 2.82 |
ENST00000007735.3
|
KRT33A
|
keratin 33A |
| chr17_-_7493390 | 2.81 |
ENST00000538513.2
ENST00000570788.1 ENST00000250055.2 |
SOX15
|
SRY (sex determining region Y)-box 15 |
| chr18_-_28682374 | 2.77 |
ENST00000280904.6
|
DSC2
|
desmocollin 2 |
| chr6_-_30654977 | 2.76 |
ENST00000399199.3
|
PPP1R18
|
protein phosphatase 1, regulatory subunit 18 |
| chr22_+_31477296 | 2.75 |
ENST00000426927.1
ENST00000440425.1 ENST00000358743.1 ENST00000347557.2 ENST00000333137.7 |
SMTN
|
smoothelin |
| chr19_-_51523412 | 2.73 |
ENST00000391805.1
ENST00000599077.1 |
KLK10
|
kallikrein-related peptidase 10 |
| chr17_+_39969183 | 2.63 |
ENST00000321562.4
|
FKBP10
|
FK506 binding protein 10, 65 kDa |
| chr20_+_33759854 | 2.57 |
ENST00000216968.4
|
PROCR
|
protein C receptor, endothelial |
| chr5_+_95998746 | 2.57 |
ENST00000508608.1
|
CAST
|
calpastatin |
| chr19_-_36004543 | 2.54 |
ENST00000339686.3
ENST00000447113.2 ENST00000440396.1 |
DMKN
|
dermokine |
| chr8_-_143867946 | 2.54 |
ENST00000301263.4
|
LY6D
|
lymphocyte antigen 6 complex, locus D |
| chr10_+_120967072 | 2.53 |
ENST00000392870.2
|
GRK5
|
G protein-coupled receptor kinase 5 |
| chr17_+_7210898 | 2.50 |
ENST00000572815.1
|
EIF5A
|
eukaryotic translation initiation factor 5A |
| chrX_-_153599578 | 2.49 |
ENST00000360319.4
ENST00000344736.4 |
FLNA
|
filamin A, alpha |
| chr1_+_55505184 | 2.48 |
ENST00000302118.5
|
PCSK9
|
proprotein convertase subtilisin/kexin type 9 |
| chr2_-_85637459 | 2.38 |
ENST00000409921.1
|
CAPG
|
capping protein (actin filament), gelsolin-like |
| chr12_-_8815215 | 2.37 |
ENST00000544889.1
ENST00000543369.1 |
MFAP5
|
microfibrillar associated protein 5 |
| chr19_-_51523275 | 2.35 |
ENST00000309958.3
|
KLK10
|
kallikrein-related peptidase 10 |
| chr17_+_7210294 | 2.34 |
ENST00000336452.7
|
EIF5A
|
eukaryotic translation initiation factor 5A |
| chr12_-_8815299 | 2.29 |
ENST00000535336.1
|
MFAP5
|
microfibrillar associated protein 5 |
| chr19_-_44285401 | 2.29 |
ENST00000262888.3
|
KCNN4
|
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 |
| chr16_+_31483451 | 2.27 |
ENST00000565360.1
ENST00000361773.3 |
TGFB1I1
|
transforming growth factor beta 1 induced transcript 1 |
| chr7_+_134430212 | 2.26 |
ENST00000436461.2
|
CALD1
|
caldesmon 1 |
| chr16_+_31483374 | 2.24 |
ENST00000394863.3
|
TGFB1I1
|
transforming growth factor beta 1 induced transcript 1 |
| chr17_+_33914460 | 2.22 |
ENST00000537622.2
|
AP2B1
|
adaptor-related protein complex 2, beta 1 subunit |
| chr2_-_177502659 | 2.21 |
ENST00000295549.4
|
AC017048.3
|
long intergenic non-protein coding RNA 1116 |
| chr17_-_34122596 | 2.15 |
ENST00000250144.8
|
MMP28
|
matrix metallopeptidase 28 |
| chrX_+_56258844 | 2.11 |
ENST00000374928.3
|
KLF8
|
Kruppel-like factor 8 |
| chr17_+_33914276 | 2.06 |
ENST00000592545.1
ENST00000538556.1 ENST00000312678.8 ENST00000589344.1 |
AP2B1
|
adaptor-related protein complex 2, beta 1 subunit |
| chr6_+_106546808 | 1.99 |
ENST00000369089.3
|
PRDM1
|
PR domain containing 1, with ZNF domain |
| chr19_-_51522955 | 1.99 |
ENST00000358789.3
|
KLK10
|
kallikrein-related peptidase 10 |
| chr4_-_48018580 | 1.97 |
ENST00000514170.1
|
CNGA1
|
cyclic nucleotide gated channel alpha 1 |
| chr18_+_21452964 | 1.97 |
ENST00000587184.1
|
LAMA3
|
laminin, alpha 3 |
| chr14_-_57272366 | 1.96 |
ENST00000554788.1
ENST00000554845.1 ENST00000408990.3 |
OTX2
|
orthodenticle homeobox 2 |
| chr1_-_6526192 | 1.89 |
ENST00000377782.3
ENST00000351959.5 ENST00000356876.3 |
TNFRSF25
|
tumor necrosis factor receptor superfamily, member 25 |
| chr8_-_101963482 | 1.87 |
ENST00000419477.2
|
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr17_-_74023474 | 1.85 |
ENST00000301607.3
|
EVPL
|
envoplakin |
| chr8_-_145018080 | 1.83 |
ENST00000354589.3
|
PLEC
|
plectin |
| chr17_-_74023291 | 1.80 |
ENST00000586740.1
|
EVPL
|
envoplakin |
| chr7_-_102158157 | 1.80 |
ENST00000541662.1
ENST00000306682.6 ENST00000465829.1 |
RASA4B
|
RAS p21 protein activator 4B |
| chr19_+_54371114 | 1.67 |
ENST00000448420.1
ENST00000439000.1 ENST00000391770.4 ENST00000391771.1 |
MYADM
|
myeloid-associated differentiation marker |
| chr18_+_21452804 | 1.66 |
ENST00000269217.6
|
LAMA3
|
laminin, alpha 3 |
| chr1_-_27816641 | 1.62 |
ENST00000430629.2
|
WASF2
|
WAS protein family, member 2 |
| chr2_-_219151487 | 1.61 |
ENST00000444881.1
|
TMBIM1
|
transmembrane BAX inhibitor motif containing 1 |
| chr17_-_1389228 | 1.61 |
ENST00000438665.2
|
MYO1C
|
myosin IC |
| chr17_-_39661849 | 1.60 |
ENST00000246635.3
ENST00000336861.3 ENST00000587544.1 ENST00000587435.1 |
KRT13
|
keratin 13 |
| chr14_-_100841670 | 1.60 |
ENST00000557297.1
ENST00000555813.1 ENST00000557135.1 ENST00000556698.1 ENST00000554509.1 ENST00000555410.1 |
WARS
|
tryptophanyl-tRNA synthetase |
| chr1_-_117210290 | 1.59 |
ENST00000369483.1
ENST00000369486.3 |
IGSF3
|
immunoglobulin superfamily, member 3 |
| chr3_-_48130314 | 1.58 |
ENST00000439356.1
ENST00000395734.3 ENST00000426837.2 |
MAP4
|
microtubule-associated protein 4 |
| chr21_-_44496441 | 1.56 |
ENST00000359624.3
ENST00000352178.5 |
CBS
|
cystathionine-beta-synthase |
| chr1_-_11865982 | 1.54 |
ENST00000418034.1
|
MTHFR
|
methylenetetrahydrofolate reductase (NAD(P)H) |
| chr12_-_85306594 | 1.52 |
ENST00000266682.5
|
SLC6A15
|
solute carrier family 6 (neutral amino acid transporter), member 15 |
| chr5_+_95998070 | 1.52 |
ENST00000421689.2
ENST00000510756.1 ENST00000512620.1 |
CAST
|
calpastatin |
| chr7_-_102257139 | 1.50 |
ENST00000521076.1
ENST00000462172.1 ENST00000522801.1 ENST00000449970.2 ENST00000262940.7 |
RASA4
|
RAS p21 protein activator 4 |
| chr20_+_44035200 | 1.50 |
ENST00000372717.1
ENST00000360981.4 |
DBNDD2
|
dysbindin (dystrobrevin binding protein 1) domain containing 2 |
| chr21_-_44495964 | 1.48 |
ENST00000398168.1
ENST00000398165.3 |
CBS
|
cystathionine-beta-synthase |
| chr9_-_35732362 | 1.47 |
ENST00000314888.9
ENST00000540444.1 |
TLN1
|
talin 1 |
| chr1_+_11866207 | 1.46 |
ENST00000312413.6
ENST00000346436.6 |
CLCN6
|
chloride channel, voltage-sensitive 6 |
| chr4_-_90756769 | 1.45 |
ENST00000345009.4
ENST00000505199.1 ENST00000502987.1 |
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor) |
| chr16_+_46723552 | 1.44 |
ENST00000219097.2
ENST00000568364.2 |
ORC6
|
origin recognition complex, subunit 6 |
| chr22_-_36357671 | 1.43 |
ENST00000408983.2
|
RBFOX2
|
RNA binding protein, fox-1 homolog (C. elegans) 2 |
| chr6_+_106534192 | 1.40 |
ENST00000369091.2
ENST00000369096.4 |
PRDM1
|
PR domain containing 1, with ZNF domain |
| chr17_-_1389419 | 1.39 |
ENST00000575158.1
|
MYO1C
|
myosin IC |
| chr7_+_86274145 | 1.38 |
ENST00000439827.1
ENST00000394720.2 ENST00000421579.1 |
GRM3
|
glutamate receptor, metabotropic 3 |
| chr2_+_173292301 | 1.37 |
ENST00000264106.6
ENST00000375221.2 ENST00000343713.4 |
ITGA6
|
integrin, alpha 6 |
| chr20_-_62168672 | 1.35 |
ENST00000217185.2
|
PTK6
|
protein tyrosine kinase 6 |
| chr2_-_74667612 | 1.33 |
ENST00000305557.5
ENST00000233330.6 |
RTKN
|
rhotekin |
| chr3_+_26664291 | 1.31 |
ENST00000396641.2
|
LRRC3B
|
leucine rich repeat containing 3B |
| chr15_+_90931450 | 1.31 |
ENST00000268182.5
ENST00000560738.1 ENST00000560418.1 |
IQGAP1
|
IQ motif containing GTPase activating protein 1 |
| chr1_-_11866034 | 1.30 |
ENST00000376590.3
|
MTHFR
|
methylenetetrahydrofolate reductase (NAD(P)H) |
| chr5_+_110074685 | 1.29 |
ENST00000355943.3
ENST00000447245.2 |
SLC25A46
|
solute carrier family 25, member 46 |
| chr17_+_65374075 | 1.29 |
ENST00000581322.1
|
PITPNC1
|
phosphatidylinositol transfer protein, cytoplasmic 1 |
| chr1_-_39395165 | 1.26 |
ENST00000372985.3
|
RHBDL2
|
rhomboid, veinlet-like 2 (Drosophila) |
| chr17_-_43502987 | 1.25 |
ENST00000376922.2
|
ARHGAP27
|
Rho GTPase activating protein 27 |
| chr19_+_41860047 | 1.25 |
ENST00000604123.1
|
TMEM91
|
transmembrane protein 91 |
| chr1_-_6526167 | 1.24 |
ENST00000351748.3
ENST00000348333.3 |
TNFRSF25
|
tumor necrosis factor receptor superfamily, member 25 |
| chr1_-_204183071 | 1.24 |
ENST00000308302.3
|
GOLT1A
|
golgi transport 1A |
| chr9_-_72287191 | 1.24 |
ENST00000265381.4
|
APBA1
|
amyloid beta (A4) precursor protein-binding, family A, member 1 |
| chr3_-_197024965 | 1.22 |
ENST00000392382.2
|
DLG1
|
discs, large homolog 1 (Drosophila) |
| chr19_-_42916499 | 1.22 |
ENST00000601189.1
ENST00000599211.1 |
LIPE
|
lipase, hormone-sensitive |
| chr8_-_101962777 | 1.20 |
ENST00000395951.3
|
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr12_+_26274917 | 1.18 |
ENST00000538142.1
|
SSPN
|
sarcospan |
| chr1_-_26680570 | 1.18 |
ENST00000475866.2
|
AIM1L
|
absent in melanoma 1-like |
| chr19_+_39687596 | 1.17 |
ENST00000339852.4
|
NCCRP1
|
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) |
| chr6_+_41606176 | 1.16 |
ENST00000441667.1
ENST00000230321.6 ENST00000373050.4 ENST00000446650.1 ENST00000435476.1 |
MDFI
|
MyoD family inhibitor |
| chr1_-_94147385 | 1.16 |
ENST00000260502.6
|
BCAR3
|
breast cancer anti-estrogen resistance 3 |
| chr1_+_16090914 | 1.15 |
ENST00000441801.2
|
FBLIM1
|
filamin binding LIM protein 1 |
| chr11_-_73471655 | 1.14 |
ENST00000400470.2
|
RAB6A
|
RAB6A, member RAS oncogene family |
| chr13_-_20437648 | 1.11 |
ENST00000382907.4
ENST00000382905.4 |
ZMYM5
|
zinc finger, MYM-type 5 |
| chr12_+_27677085 | 1.11 |
ENST00000545334.1
ENST00000540114.1 ENST00000537927.1 ENST00000318304.8 ENST00000535047.1 ENST00000542629.1 ENST00000228425.6 |
PPFIBP1
|
PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| chr1_+_44398943 | 1.09 |
ENST00000372359.5
ENST00000414809.3 |
ARTN
|
artemin |
| chr2_-_110371664 | 1.09 |
ENST00000545389.1
ENST00000423520.1 |
SEPT10
|
septin 10 |
| chr1_+_44399466 | 1.09 |
ENST00000498139.2
ENST00000491846.1 |
ARTN
|
artemin |
| chr2_+_17721920 | 1.07 |
ENST00000295156.4
|
VSNL1
|
visinin-like 1 |
| chr12_-_8815404 | 1.07 |
ENST00000359478.2
ENST00000396549.2 |
MFAP5
|
microfibrillar associated protein 5 |
| chr6_-_43596899 | 1.06 |
ENST00000307126.5
ENST00000452781.1 |
GTPBP2
|
GTP binding protein 2 |
| chr18_-_5540471 | 1.06 |
ENST00000581833.1
ENST00000544123.1 ENST00000342933.3 ENST00000400111.3 ENST00000585142.1 |
EPB41L3
|
erythrocyte membrane protein band 4.1-like 3 |
| chr12_-_8815477 | 1.04 |
ENST00000433590.2
|
MFAP5
|
microfibrillar associated protein 5 |
| chr12_-_58131931 | 1.04 |
ENST00000547588.1
|
AGAP2
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| chr2_+_173292280 | 1.04 |
ENST00000264107.7
|
ITGA6
|
integrin, alpha 6 |
| chrX_-_54824673 | 1.03 |
ENST00000218436.6
|
ITIH6
|
inter-alpha-trypsin inhibitor heavy chain family, member 6 |
| chr2_+_233243233 | 1.02 |
ENST00000392027.2
|
ALPP
|
alkaline phosphatase, placental |
| chr3_-_48632593 | 1.01 |
ENST00000454817.1
ENST00000328333.8 |
COL7A1
|
collagen, type VII, alpha 1 |
| chr20_+_35974532 | 1.01 |
ENST00000373578.2
|
SRC
|
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog |
| chr4_+_110481348 | 1.01 |
ENST00000394650.4
|
CCDC109B
|
coiled-coil domain containing 109B |
| chr16_+_89989687 | 1.00 |
ENST00000315491.7
ENST00000555576.1 ENST00000554336.1 ENST00000553967.1 |
TUBB3
|
Tubulin beta-3 chain |
| chr12_+_51632666 | 0.99 |
ENST00000604900.1
|
DAZAP2
|
DAZ associated protein 2 |
| chr3_-_197024394 | 0.99 |
ENST00000434148.1
ENST00000412364.2 ENST00000436682.1 ENST00000456699.2 ENST00000392380.2 |
DLG1
|
discs, large homolog 1 (Drosophila) |
| chr2_+_173292390 | 0.99 |
ENST00000442250.1
ENST00000458358.1 ENST00000409080.1 |
ITGA6
|
integrin, alpha 6 |
| chr1_+_36771946 | 0.99 |
ENST00000373139.2
ENST00000453908.2 ENST00000426732.2 |
SH3D21
|
SH3 domain containing 21 |
| chr19_-_18654293 | 0.97 |
ENST00000597547.1
ENST00000222308.4 ENST00000544835.3 ENST00000610101.1 ENST00000597960.3 ENST00000608443.1 |
FKBP8
|
FK506 binding protein 8, 38kDa |
| chr12_-_108154925 | 0.97 |
ENST00000228437.5
|
PRDM4
|
PR domain containing 4 |
| chr14_-_65409502 | 0.97 |
ENST00000389614.5
|
GPX2
|
glutathione peroxidase 2 (gastrointestinal) |
| chr19_+_1077393 | 0.97 |
ENST00000590577.1
|
HMHA1
|
histocompatibility (minor) HA-1 |
| chr1_-_43833628 | 0.97 |
ENST00000413844.2
ENST00000372458.3 |
ELOVL1
|
ELOVL fatty acid elongase 1 |
| chr13_-_20437772 | 0.96 |
ENST00000337963.4
|
ZMYM5
|
zinc finger, MYM-type 5 |
| chr2_-_9771075 | 0.96 |
ENST00000446619.1
ENST00000238081.3 |
YWHAQ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta |
| chr1_-_154155595 | 0.95 |
ENST00000328159.4
ENST00000368531.2 ENST00000323144.7 ENST00000368533.3 ENST00000341372.3 |
TPM3
|
tropomyosin 3 |
| chr1_-_205744205 | 0.94 |
ENST00000446390.2
|
RAB7L1
|
RAB7, member RAS oncogene family-like 1 |
| chr4_+_48018781 | 0.93 |
ENST00000295461.5
|
NIPAL1
|
NIPA-like domain containing 1 |
| chr1_-_205744574 | 0.93 |
ENST00000367139.3
ENST00000235932.4 ENST00000437324.2 ENST00000414729.1 |
RAB7L1
|
RAB7, member RAS oncogene family-like 1 |
| chr8_+_26435359 | 0.93 |
ENST00000311151.5
|
DPYSL2
|
dihydropyrimidinase-like 2 |
| chr3_+_38206975 | 0.91 |
ENST00000446845.1
ENST00000311806.3 |
OXSR1
|
oxidative stress responsive 1 |
| chr10_+_105036909 | 0.91 |
ENST00000369849.4
|
INA
|
internexin neuronal intermediate filament protein, alpha |
| chr2_-_177502254 | 0.91 |
ENST00000339037.3
|
AC017048.3
|
long intergenic non-protein coding RNA 1116 |
| chr15_+_43425672 | 0.91 |
ENST00000260403.2
|
TMEM62
|
transmembrane protein 62 |
| chr11_+_117049854 | 0.90 |
ENST00000278951.7
|
SIDT2
|
SID1 transmembrane family, member 2 |
| chr11_+_117049910 | 0.89 |
ENST00000431081.2
ENST00000524842.1 |
SIDT2
|
SID1 transmembrane family, member 2 |
| chr3_-_106959424 | 0.89 |
ENST00000607801.1
ENST00000479612.2 ENST00000484698.1 ENST00000477210.2 ENST00000473636.1 |
LINC00882
|
long intergenic non-protein coding RNA 882 |
| chr17_+_18280976 | 0.87 |
ENST00000399134.4
|
EVPLL
|
envoplakin-like |
| chr15_+_90792760 | 0.86 |
ENST00000339615.5
ENST00000438251.1 |
TTLL13
|
tubulin tyrosine ligase-like family, member 13 |
| chr1_-_159893507 | 0.86 |
ENST00000368096.1
|
TAGLN2
|
transgelin 2 |
| chr8_-_22089533 | 0.85 |
ENST00000321613.3
|
PHYHIP
|
phytanoyl-CoA 2-hydroxylase interacting protein |
| chr3_-_127542021 | 0.84 |
ENST00000434178.2
|
MGLL
|
monoglyceride lipase |
| chr16_+_30075463 | 0.84 |
ENST00000562168.1
ENST00000569545.1 |
ALDOA
|
aldolase A, fructose-bisphosphate |
| chr1_-_222885770 | 0.83 |
ENST00000355727.2
ENST00000340020.6 |
AIDA
|
axin interactor, dorsalization associated |
| chr10_+_47746929 | 0.83 |
ENST00000340243.6
ENST00000374277.5 ENST00000449464.2 ENST00000538825.1 ENST00000335083.5 |
ANXA8L2
AL603965.1
|
annexin A8-like 2 Protein LOC100996760 |
| chr1_-_154155675 | 0.83 |
ENST00000330188.9
ENST00000341485.5 |
TPM3
|
tropomyosin 3 |
| chr12_-_54778471 | 0.83 |
ENST00000550120.1
ENST00000394313.2 ENST00000547210.1 |
ZNF385A
|
zinc finger protein 385A |
| chr22_-_45809446 | 0.81 |
ENST00000357450.4
|
SMC1B
|
structural maintenance of chromosomes 1B |
| chr2_+_153574428 | 0.81 |
ENST00000326446.5
|
ARL6IP6
|
ADP-ribosylation-like factor 6 interacting protein 6 |
| chr11_+_65657875 | 0.79 |
ENST00000312579.2
|
CCDC85B
|
coiled-coil domain containing 85B |
| chrX_-_23761317 | 0.79 |
ENST00000492081.1
ENST00000379303.5 ENST00000336430.7 |
ACOT9
|
acyl-CoA thioesterase 9 |
| chr11_-_62689046 | 0.79 |
ENST00000306960.3
ENST00000543973.1 |
CHRM1
|
cholinergic receptor, muscarinic 1 |
| chr2_+_172950227 | 0.79 |
ENST00000341900.6
|
DLX1
|
distal-less homeobox 1 |
| chr20_+_44035847 | 0.78 |
ENST00000372712.2
|
DBNDD2
|
dysbindin (dystrobrevin binding protein 1) domain containing 2 |
| chr1_+_28052518 | 0.78 |
ENST00000530324.1
ENST00000234549.7 ENST00000373949.1 ENST00000010299.6 |
FAM76A
|
family with sequence similarity 76, member A |
| chr17_-_39538550 | 0.78 |
ENST00000394001.1
|
KRT34
|
keratin 34 |
| chr15_-_64648273 | 0.77 |
ENST00000607537.1
ENST00000303052.7 ENST00000303032.6 |
CSNK1G1
|
casein kinase 1, gamma 1 |
| chr17_-_27405875 | 0.77 |
ENST00000359450.6
|
TIAF1
|
TGFB1-induced anti-apoptotic factor 1 |
| chr3_+_50192537 | 0.76 |
ENST00000002829.3
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr9_-_35111570 | 0.75 |
ENST00000378561.1
ENST00000603301.1 |
FAM214B
|
family with sequence similarity 214, member B |
| chr2_+_85132749 | 0.75 |
ENST00000233143.4
|
TMSB10
|
thymosin beta 10 |
| chr3_+_50192499 | 0.74 |
ENST00000413852.1
|
SEMA3F
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| chr8_+_38614807 | 0.74 |
ENST00000330691.6
ENST00000348567.4 |
TACC1
|
transforming, acidic coiled-coil containing protein 1 |
| chr17_-_39023462 | 0.74 |
ENST00000251643.4
|
KRT12
|
keratin 12 |
| chr3_+_10857885 | 0.73 |
ENST00000254488.2
ENST00000454147.1 |
SLC6A11
|
solute carrier family 6 (neurotransmitter transporter), member 11 |
| chr15_+_42131011 | 0.73 |
ENST00000458483.1
|
PLA2G4B
|
phospholipase A2, group IVB (cytosolic) |
| chr11_+_1860682 | 0.73 |
ENST00000381906.1
|
TNNI2
|
troponin I type 2 (skeletal, fast) |
| chr11_+_1860832 | 0.73 |
ENST00000252898.7
|
TNNI2
|
troponin I type 2 (skeletal, fast) |
| chrX_+_47077632 | 0.72 |
ENST00000457458.2
|
CDK16
|
cyclin-dependent kinase 16 |
| chr3_+_50273625 | 0.72 |
ENST00000536647.1
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| chr1_-_24126051 | 0.72 |
ENST00000445705.1
|
GALE
|
UDP-galactose-4-epimerase |
| chr2_-_220174166 | 0.72 |
ENST00000409251.3
ENST00000451506.1 ENST00000295718.2 ENST00000446182.1 |
PTPRN
|
protein tyrosine phosphatase, receptor type, N |
| chr5_+_159895275 | 0.71 |
ENST00000517927.1
|
MIR146A
|
microRNA 146a |
| chr3_-_49449350 | 0.71 |
ENST00000454011.2
ENST00000445425.1 ENST00000422781.1 |
RHOA
|
ras homolog family member A |
| chr16_+_30075595 | 0.71 |
ENST00000563060.2
|
ALDOA
|
aldolase A, fructose-bisphosphate |
| chr19_+_8117636 | 0.70 |
ENST00000253451.4
ENST00000315626.4 |
CCL25
|
chemokine (C-C motif) ligand 25 |
| chr14_-_65409438 | 0.70 |
ENST00000557049.1
|
GPX2
|
glutathione peroxidase 2 (gastrointestinal) |
| chr5_+_89770664 | 0.70 |
ENST00000503973.1
ENST00000399107.1 |
POLR3G
|
polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| chr10_+_94608218 | 0.69 |
ENST00000371543.1
|
EXOC6
|
exocyst complex component 6 |
| chr1_-_115212696 | 0.69 |
ENST00000393276.3
ENST00000393277.1 |
DENND2C
|
DENN/MADD domain containing 2C |
| chr1_+_10092890 | 0.69 |
ENST00000253251.8
ENST00000377157.3 |
UBE4B
|
ubiquitination factor E4B |
| chr16_+_30078811 | 0.69 |
ENST00000564688.1
|
ALDOA
|
aldolase A, fructose-bisphosphate |
| chr14_-_23623577 | 0.69 |
ENST00000422941.2
ENST00000453702.1 |
SLC7A8
|
solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| chr9_-_35111420 | 0.68 |
ENST00000378557.1
|
FAM214B
|
family with sequence similarity 214, member B |
| chr6_+_33589161 | 0.68 |
ENST00000605930.1
|
ITPR3
|
inositol 1,4,5-trisphosphate receptor, type 3 |
| chr4_-_165305086 | 0.67 |
ENST00000507270.1
ENST00000514618.1 ENST00000503008.1 |
MARCH1
|
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase |
| chr3_-_113465065 | 0.67 |
ENST00000497255.1
ENST00000478020.1 ENST00000240922.3 ENST00000493900.1 |
NAA50
|
N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| chr17_-_39942940 | 0.67 |
ENST00000310706.5
ENST00000393931.3 ENST00000424457.1 ENST00000591690.1 |
JUP
|
junction plakoglobin |
| chr3_+_8775466 | 0.67 |
ENST00000343849.2
ENST00000397368.2 |
CAV3
|
caveolin 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 11.4 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 1.4 | 11.4 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 1.0 | 3.0 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 0.9 | 2.8 | GO:0048627 | myoblast development(GO:0048627) |
| 0.9 | 2.6 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 0.9 | 4.3 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.8 | 2.5 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.7 | 3.4 | GO:0033078 | extrathymic T cell differentiation(GO:0033078) |
| 0.6 | 3.4 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.6 | 2.8 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.5 | 4.5 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.5 | 3.0 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.4 | 5.3 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.4 | 2.2 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021) |
| 0.4 | 1.3 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 0.4 | 2.1 | GO:0010760 | negative regulation of macrophage chemotaxis(GO:0010760) |
| 0.4 | 2.5 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.4 | 3.8 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.4 | 1.7 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.4 | 2.5 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) |
| 0.4 | 1.6 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 0.4 | 2.4 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.3 | 1.0 | GO:1903925 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.3 | 1.6 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.3 | 8.8 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 0.9 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.3 | 2.4 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.3 | 4.1 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.3 | 1.5 | GO:1903285 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.3 | 2.8 | GO:1900004 | negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572) |
| 0.3 | 2.2 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.3 | 1.1 | GO:0021592 | fourth ventricle development(GO:0021592) |
| 0.3 | 1.6 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.3 | 0.8 | GO:0021898 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869) |
| 0.3 | 0.5 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.3 | 2.8 | GO:0015824 | proline transport(GO:0015824) |
| 0.3 | 2.5 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.3 | 1.0 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.2 | 1.2 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.2 | 0.9 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.2 | 3.5 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.2 | 2.5 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 0.2 | 1.1 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.2 | 0.9 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 0.2 | 3.4 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.2 | 1.3 | GO:0032185 | septin cytoskeleton organization(GO:0032185) |
| 0.2 | 0.7 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.2 | 1.7 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.2 | 5.5 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.2 | 1.5 | GO:0036486 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
| 0.2 | 6.0 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.2 | 0.7 | GO:1990502 | dense core granule maturation(GO:1990502) |
| 0.2 | 0.5 | GO:0051885 | positive regulation of anagen(GO:0051885) |
| 0.2 | 21.6 | GO:0070268 | cornification(GO:0070268) |
| 0.2 | 0.5 | GO:0001560 | regulation of cell growth by extracellular stimulus(GO:0001560) |
| 0.2 | 0.5 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166) |
| 0.2 | 1.0 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.2 | 2.9 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.2 | 1.1 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.2 | 0.6 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 0.1 | 1.0 | GO:0051511 | regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814) |
| 0.1 | 1.0 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.1 | 0.4 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 0.1 | 0.4 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 0.1 | 0.6 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 0.1 | 1.6 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.1 | 0.6 | GO:0016333 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 0.1 | 2.4 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 0.4 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.1 | 0.7 | GO:0050917 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 0.1 | 0.5 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.1 | 0.7 | GO:0060373 | T-tubule organization(GO:0033292) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 1.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 0.8 | GO:0071926 | endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 0.6 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) |
| 0.1 | 2.9 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 1.2 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 0.1 | 0.5 | GO:0051586 | glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168) |
| 0.1 | 0.5 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 0.1 | 0.8 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.1 | 1.0 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 2.6 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 1.3 | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 0.1 | 0.7 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 0.1 | 2.0 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.1 | 0.6 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 0.2 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 0.5 | GO:0002281 | macrophage activation involved in immune response(GO:0002281) |
| 0.1 | 0.3 | GO:0002352 | B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.1 | 0.5 | GO:0010481 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 0.1 | 1.4 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.1 | 0.9 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.1 | 0.6 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.1 | 0.4 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.1 | 0.6 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 0.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 2.3 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.1 | 0.3 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 0.1 | 1.3 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.1 | 0.3 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 0.1 | 0.4 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 3.7 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.1 | 0.4 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 0.1 | 1.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 4.0 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 1.4 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.1 | 0.4 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.1 | 1.4 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.1 | 0.7 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 0.2 | GO:0032679 | TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) |
| 0.1 | 1.2 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.1 | 0.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.1 | 0.6 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 0.7 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 0.3 | GO:0035672 | oligopeptide transmembrane transport(GO:0035672) |
| 0.1 | 0.2 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 2.0 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 0.6 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
| 0.0 | 2.6 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.0 | 1.2 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.3 | GO:2000370 | positive regulation of clathrin-mediated endocytosis(GO:2000370) |
| 0.0 | 0.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 3.3 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 0.0 | 0.6 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 3.3 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 1.0 | GO:0021904 | dorsal/ventral neural tube patterning(GO:0021904) |
| 0.0 | 0.8 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 0.8 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.2 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.0 | 0.3 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.0 | 0.2 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 0.7 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.0 | 1.3 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.1 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
| 0.0 | 0.0 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 0.0 | 0.7 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.0 | 0.3 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.0 | 0.7 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.0 | 1.1 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
| 0.0 | 0.4 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.0 | 1.0 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 1.4 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.1 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
| 0.0 | 0.2 | GO:0043587 | tongue morphogenesis(GO:0043587) |
| 0.0 | 0.0 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.0 | 0.3 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 0.4 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.0 | 0.1 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.0 | 0.3 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 0.0 | 0.8 | GO:0007249 | I-kappaB kinase/NF-kappaB signaling(GO:0007249) |
| 0.0 | 1.2 | GO:0008284 | positive regulation of cell proliferation(GO:0008284) |
| 0.0 | 0.4 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.0 | 0.6 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.2 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.0 | 0.3 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.0 | 1.3 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.2 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.0 | 0.6 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.1 | GO:0009304 | tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.0 | 0.4 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.0 | 0.4 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.3 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.0 | 2.7 | GO:0006939 | smooth muscle contraction(GO:0006939) |
| 0.0 | 0.5 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.7 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 0.5 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
| 0.0 | 0.3 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.0 | 0.6 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.0 | 0.2 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.2 | GO:0006402 | mRNA catabolic process(GO:0006402) |
| 0.0 | 1.0 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.3 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 0.6 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.0 | 0.1 | GO:0051122 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
| 0.0 | 0.5 | GO:0071371 | cellular response to gonadotropin stimulus(GO:0071371) |
| 0.0 | 0.2 | GO:1904903 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.0 | 1.2 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.0 | 0.1 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.0 | 0.2 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.0 | 1.0 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.1 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 1.4 | GO:0051782 | negative regulation of cell division(GO:0051782) |
| 0.0 | 0.2 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.0 | 0.9 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.0 | 0.4 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.0 | 0.4 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.0 | 1.0 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.2 | GO:0021794 | thalamus development(GO:0021794) |
| 0.0 | 0.5 | GO:0051966 | regulation of synaptic transmission, glutamatergic(GO:0051966) |
| 0.0 | 0.2 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.0 | 0.2 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.4 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.0 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.4 | GO:0034676 | integrin alpha6-beta4 complex(GO:0034676) |
| 0.9 | 11.4 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.8 | 2.5 | GO:0031523 | Myb complex(GO:0031523) |
| 0.8 | 2.5 | GO:1990666 | PCSK9-LDLR complex(GO:1990666) |
| 0.8 | 3.0 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.5 | 3.6 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.3 | 11.3 | GO:0030057 | desmosome(GO:0030057) |
| 0.3 | 4.7 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.3 | 6.8 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 1.0 | GO:0030934 | anchoring collagen complex(GO:0030934) |
| 0.2 | 4.7 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.2 | 1.1 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.2 | 0.8 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.2 | 6.9 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.2 | 3.1 | GO:0008091 | spectrin(GO:0008091) |
| 0.2 | 1.1 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.2 | 2.2 | GO:0043219 | lateral loop(GO:0043219) |
| 0.2 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.2 | 2.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.2 | 2.3 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 0.7 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.1 | 1.3 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 3.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 1.0 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 1.1 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 6.1 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 1.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.4 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.1 | 0.6 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.1 | 18.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 2.0 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.6 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 1.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 0.6 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 1.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.3 | GO:0031417 | NatC complex(GO:0031417) |
| 0.1 | 0.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.1 | 1.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 0.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.1 | 2.9 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 1.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.7 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.4 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.8 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.6 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.0 | 0.7 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 1.7 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.9 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.9 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 2.2 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.6 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.7 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 0.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.3 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 3.9 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 6.2 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 12.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.2 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.0 | 0.7 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 3.2 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.1 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.2 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 2.6 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.4 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.0 | 0.4 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.1 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 1.1 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 1.6 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.5 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 0.6 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 1.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.6 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 7.7 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 1.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.2 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.7 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.1 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 1.4 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 0.4 | GO:0043204 | perikaryon(GO:0043204) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 11.4 | GO:0030395 | lactose binding(GO:0030395) |
| 1.0 | 3.0 | GO:0050421 | cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 0.8 | 2.5 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.8 | 2.5 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 0.7 | 4.8 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.7 | 4.1 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.7 | 2.0 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
| 0.6 | 11.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.6 | 2.4 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.6 | 2.8 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.5 | 4.5 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.5 | 2.3 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.5 | 3.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.4 | 3.8 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.4 | 1.2 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.3 | 1.3 | GO:0003974 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 0.3 | 1.6 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.3 | 0.9 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.3 | 1.8 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.3 | 1.5 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.3 | 1.4 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.3 | 2.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.3 | 2.9 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.2 | 5.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.2 | 0.9 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
| 0.2 | 1.3 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.2 | 2.2 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.2 | 0.9 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.2 | 4.7 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 0.8 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.2 | 0.2 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.2 | 2.3 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.2 | 1.4 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 0.7 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.2 | 1.7 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 3.7 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.2 | 0.5 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 0.2 | 0.6 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 5.6 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 0.6 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 0.4 | GO:0052595 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
| 0.1 | 1.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 1.9 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 1.1 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.1 | 1.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 1.5 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.7 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.1 | 0.5 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.1 | 0.8 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.7 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.1 | 1.0 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.1 | 1.0 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.6 | GO:0004473 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.1 | 0.5 | GO:0008401 | retinoic acid 4-hydroxylase activity(GO:0008401) |
| 0.1 | 2.0 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 2.0 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 0.3 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 1.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 1.4 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 0.3 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.1 | 2.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 3.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 3.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 2.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 0.2 | GO:0047661 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
| 0.1 | 2.6 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.7 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.5 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 2.0 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.1 | 0.7 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 6.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 1.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 6.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 8.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.8 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 0.5 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.0 | 0.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 1.1 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.5 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 1.6 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 1.1 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.9 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.1 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.0 | 0.2 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.0 | 4.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.8 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.5 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.0 | 0.6 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.1 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 0.0 | 0.1 | GO:0004052 | arachidonate 12-lipoxygenase activity(GO:0004052) |
| 0.0 | 6.0 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.5 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.0 | 0.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 1.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.9 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.8 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 3.3 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.0 | 0.2 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.2 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.0 | 0.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.5 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.7 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 1.3 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 0.1 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307) |
| 0.0 | 1.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 2.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.5 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 12.9 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 3.3 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 1.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.5 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.2 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.0 | 0.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 2.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.3 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.3 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.0 | 4.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 4.9 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.5 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 0.3 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.0 | 0.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 0.2 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.5 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.0 | 3.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.4 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.3 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.0 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.0 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.3 | 0.3 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.2 | 11.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.2 | 11.2 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 4.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 6.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 7.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 4.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 5.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 2.9 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 1.2 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 3.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.0 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.6 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.3 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.8 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.0 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.8 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 1.1 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 3.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.0 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 9.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.5 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.5 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 0.7 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 1.8 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 4.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 2.2 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 0.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.3 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 1.0 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.5 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.0 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.4 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 0.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.9 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.2 | 4.7 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.2 | 3.5 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.2 | 7.0 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 3.5 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 3.5 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 6.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 3.5 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.5 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 2.9 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 2.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 2.2 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.8 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 1.0 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 1.4 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 2.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.7 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 1.1 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.6 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.0 | 1.0 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 1.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.6 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 1.3 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 2.5 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.4 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 1.0 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 1.0 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.7 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 3.3 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 0.5 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.9 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.4 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 2.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.5 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.0 | 1.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.6 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.0 | 0.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 1.8 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.5 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 0.6 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.5 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |