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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for KLF15

Z-value: 0.61

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Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
KLF15
ENSG00000163884.3 Kruppel like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF15hg19_v2_chr3_-_126076264_126076305-0.029.2e-01Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_29595779 2.77 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_1874200 1.33 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr7_+_94285637 1.19 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr14_-_65439132 1.15 ENST00000533601.2
RAB15
RAB15, member RAS oncogene family
chr7_-_154863264 1.06 ENST00000395731.2
ENST00000543018.1
HTR5A-AS1
HTR5A antisense RNA 1
chr22_-_50970506 0.99 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr4_+_74702214 0.98 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr8_+_81397876 0.92 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr18_-_45935663 0.89 ENST00000589194.1
ENST00000591279.1
ENST00000590855.1
ENST00000587107.1
ENST00000588970.1
ENST00000586525.1
ENST00000592387.1
ENST00000590800.1
ZBTB7C
zinc finger and BTB domain containing 7C
chr3_-_12200851 0.87 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr18_-_74207146 0.85 ENST00000443185.2
ZNF516
zinc finger protein 516
chrX_-_48693955 0.80 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr3_+_238273 0.79 ENST00000256509.2
CHL1
cell adhesion molecule L1-like
chr14_-_65438865 0.78 ENST00000267512.5
RAB15
RAB15, member RAS oncogene family
chr7_-_99869799 0.75 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr7_-_94285511 0.73 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr4_+_55524085 0.71 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr19_+_11457232 0.70 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr15_-_45480153 0.66 ENST00000560471.1
ENST00000560540.1
SHF
Src homology 2 domain containing F
chr7_-_94285402 0.66 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr6_-_80247105 0.65 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr17_-_4545170 0.64 ENST00000576394.1
ENST00000574640.1
ALOX15
arachidonate 15-lipoxygenase
chr6_-_80247140 0.62 ENST00000392959.1
ENST00000467898.3
LCA5
Leber congenital amaurosis 5
chr7_-_94285472 0.60 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr12_+_19282643 0.60 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr7_-_76256557 0.58 ENST00000275569.4
ENST00000310842.4
POMZP3
POM121 and ZP3 fusion
chr17_+_55333876 0.52 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr1_-_47407097 0.51 ENST00000457840.2
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr11_+_45918092 0.51 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr17_-_41984835 0.50 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr10_+_35415851 0.48 ENST00000374726.3
CREM
cAMP responsive element modulator
chr17_+_30593195 0.48 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr5_+_17217669 0.47 ENST00000322611.3
BASP1
brain abundant, membrane attached signal protein 1
chr6_+_32811885 0.46 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr20_+_37353084 0.45 ENST00000217420.1
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
chr19_+_50706866 0.45 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr15_-_45480147 0.45 ENST00000560734.1
SHF
Src homology 2 domain containing F
chr13_+_95364963 0.45 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr12_-_131323754 0.44 ENST00000261653.6
STX2
syntaxin 2
chr5_+_140254884 0.43 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr14_-_36983034 0.43 ENST00000518529.2
SFTA3
surfactant associated 3
chr17_-_4463856 0.41 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr17_-_63556414 0.41 ENST00000585045.1
AXIN2
axin 2
chr19_+_14544099 0.41 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr22_-_46373004 0.39 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr1_-_204654826 0.39 ENST00000367177.3
LRRN2
leucine rich repeat neuronal 2
chr16_-_30107491 0.39 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr14_+_32546274 0.38 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr20_+_13976015 0.38 ENST00000217246.4
MACROD2
MACRO domain containing 2
chr1_+_61547405 0.38 ENST00000371189.4
NFIA
nuclear factor I/A
chr4_-_39640700 0.37 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr1_-_204654481 0.37 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr2_-_233792837 0.37 ENST00000373552.4
ENST00000409079.1
NGEF
neuronal guanine nucleotide exchange factor
chr19_-_3062465 0.36 ENST00000327141.4
AES
amino-terminal enhancer of split
chr5_+_42423872 0.36 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr1_+_61548225 0.36 ENST00000371187.3
NFIA
nuclear factor I/A
chr13_+_98795505 0.36 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr19_-_38806560 0.36 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr21_-_40685504 0.35 ENST00000380800.3
BRWD1
bromodomain and WD repeat domain containing 1
chr14_-_67982146 0.35 ENST00000557779.1
ENST00000557006.1
TMEM229B
transmembrane protein 229B
chr13_+_98795434 0.35 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr19_-_38806540 0.35 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr1_-_32801825 0.34 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr5_+_110559603 0.33 ENST00000512453.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr21_-_40685477 0.33 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr18_+_13218769 0.33 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr4_-_39640513 0.33 ENST00000511809.1
ENST00000505729.1
SMIM14
small integral membrane protein 14
chr22_-_31741757 0.33 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr11_-_8954491 0.32 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16
chromosome 11 open reading frame 16
chr3_+_12838161 0.32 ENST00000456430.2
CAND2
cullin-associated and neddylation-dissociated 2 (putative)
chr14_-_67981916 0.32 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr15_+_57668695 0.31 ENST00000281282.5
CGNL1
cingulin-like 1
chr3_+_195943369 0.31 ENST00000296327.5
SLC51A
solute carrier family 51, alpha subunit
chr1_-_40367668 0.31 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr17_+_55334364 0.31 ENST00000322684.3
ENST00000579590.1
MSI2
musashi RNA-binding protein 2
chr10_+_35416223 0.31 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr10_+_60272814 0.30 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr2_+_97481974 0.30 ENST00000377060.3
ENST00000305510.3
CNNM3
cyclin M3
chr17_-_42276574 0.30 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr14_-_67981870 0.30 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr11_-_46142615 0.29 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr6_-_79787902 0.29 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr1_-_47407111 0.28 ENST00000371904.4
CYP4A11
cytochrome P450, family 4, subfamily A, polypeptide 11
chr9_+_86595626 0.27 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr12_+_9067123 0.27 ENST00000543824.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr16_+_2802623 0.27 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr19_+_11457175 0.27 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr11_-_110583451 0.26 ENST00000260283.4
ENST00000528829.1
ARHGAP20
Rho GTPase activating protein 20
chr2_+_45878790 0.26 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr11_-_77531752 0.25 ENST00000440064.2
ENST00000528095.1
RSF1
remodeling and spacing factor 1
chr10_+_21823079 0.25 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_+_36273743 0.25 ENST00000373210.3
AGO4
argonaute RISC catalytic component 4
chr5_+_139505520 0.25 ENST00000333305.3
IGIP
IgA-inducing protein
chr3_+_111718173 0.25 ENST00000494932.1
TAGLN3
transgelin 3
chr7_-_73097741 0.25 ENST00000395176.2
DNAJC30
DnaJ (Hsp40) homolog, subfamily C, member 30
chr3_-_113415441 0.25 ENST00000491165.1
ENST00000316407.4
KIAA2018
KIAA2018
chr19_-_49565254 0.24 ENST00000593537.1
NTF4
neurotrophin 4
chr11_+_17756279 0.24 ENST00000265969.6
KCNC1
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr3_-_27763803 0.24 ENST00000449599.1
EOMES
eomesodermin
chr9_+_125703282 0.24 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr2_+_232573208 0.24 ENST00000409115.3
PTMA
prothymosin, alpha
chr3_+_184097905 0.24 ENST00000450923.1
CHRD
chordin
chr11_-_102323740 0.24 ENST00000398136.2
TMEM123
transmembrane protein 123
chr5_+_102594403 0.23 ENST00000319933.2
C5orf30
chromosome 5 open reading frame 30
chr6_-_119670919 0.23 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr7_+_30323923 0.23 ENST00000323037.4
ZNRF2
zinc and ring finger 2
chr20_-_61493115 0.23 ENST00000335351.3
ENST00000217162.5
TCFL5
transcription factor-like 5 (basic helix-loop-helix)
chr7_-_100493482 0.23 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr11_-_72496976 0.23 ENST00000539138.1
ENST00000542989.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr3_+_88108381 0.23 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr5_-_111093081 0.23 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr14_+_32546145 0.23 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr22_+_39745930 0.22 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
SYNGR1
synaptogyrin 1
chr12_-_131323719 0.22 ENST00000392373.2
STX2
syntaxin 2
chr14_-_21493884 0.22 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr11_-_64612041 0.21 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr1_+_206730484 0.21 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr21_+_46825032 0.21 ENST00000400337.2
COL18A1
collagen, type XVIII, alpha 1
chr3_-_11610255 0.21 ENST00000424529.2
VGLL4
vestigial like 4 (Drosophila)
chr9_-_112260531 0.21 ENST00000374541.2
ENST00000262539.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr14_-_21493649 0.21 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chr14_-_21493123 0.21 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr5_+_139175380 0.20 ENST00000274710.3
PSD2
pleckstrin and Sec7 domain containing 2
chr15_+_76352178 0.20 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr3_+_73045936 0.20 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr3_+_184098065 0.20 ENST00000348986.3
CHRD
chordin
chr8_+_30241934 0.20 ENST00000538486.1
RBPMS
RNA binding protein with multiple splicing
chr17_+_65821780 0.20 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr3_+_38495333 0.20 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr10_-_52383644 0.20 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr10_-_15210615 0.20 ENST00000378150.1
NMT2
N-myristoyltransferase 2
chr20_-_62710832 0.20 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr19_-_45661995 0.20 ENST00000438936.2
NKPD1
NTPase, KAP family P-loop domain containing 1
chr7_+_128312346 0.20 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
FAM71F2
family with sequence similarity 71, member F2
chr14_+_55738021 0.19 ENST00000313833.4
FBXO34
F-box protein 34
chr11_-_46142948 0.19 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr6_+_31865552 0.19 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr14_-_89883412 0.19 ENST00000557258.1
FOXN3
forkhead box N3
chr14_+_90528109 0.19 ENST00000282146.4
KCNK13
potassium channel, subfamily K, member 13
chr11_-_77531858 0.19 ENST00000360355.2
RSF1
remodeling and spacing factor 1
chr2_+_48757278 0.19 ENST00000404752.1
ENST00000406226.1
STON1
stonin 1
chr17_+_42634844 0.19 ENST00000315323.3
FZD2
frizzled family receptor 2
chr3_-_71774516 0.19 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr11_-_46142505 0.19 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr13_-_45151259 0.19 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr6_+_31683117 0.18 ENST00000375825.3
ENST00000375824.1
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr6_-_99395787 0.18 ENST00000369244.2
ENST00000229971.1
FBXL4
F-box and leucine-rich repeat protein 4
chr12_+_26274917 0.18 ENST00000538142.1
SSPN
sarcospan
chr16_+_50187556 0.18 ENST00000561678.1
ENST00000357464.3
PAPD5
PAP associated domain containing 5
chr12_+_68042495 0.18 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr9_-_84303269 0.18 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_+_39893043 0.18 ENST00000281961.2
TMEM178A
transmembrane protein 178A
chr2_+_139259324 0.18 ENST00000280098.4
SPOPL
speckle-type POZ protein-like
chr7_+_89841024 0.18 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr7_-_100493744 0.18 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr1_-_177133818 0.18 ENST00000424564.2
ENST00000361833.2
ASTN1
astrotactin 1
chr8_+_30241995 0.18 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
RBPMS
RNA binding protein with multiple splicing
chr2_-_198650037 0.18 ENST00000392296.4
BOLL
boule-like RNA-binding protein
chr1_+_203765437 0.17 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr3_+_184097836 0.17 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr6_+_6588316 0.17 ENST00000379953.2
LY86
lymphocyte antigen 86
chr9_-_14313893 0.17 ENST00000380921.3
ENST00000380959.3
NFIB
nuclear factor I/B
chr10_+_22610124 0.17 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr14_+_58765103 0.17 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr7_-_150675372 0.17 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_+_89841000 0.16 ENST00000287908.3
STEAP2
STEAP family member 2, metalloreductase
chr17_-_41985096 0.16 ENST00000269095.4
ENST00000523220.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr2_+_232573222 0.16 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr19_+_56154913 0.16 ENST00000270451.5
ENST00000588537.1
ZNF581
zinc finger protein 581
chr18_-_5895954 0.16 ENST00000581347.2
TMEM200C
transmembrane protein 200C
chr17_+_19912640 0.16 ENST00000395527.4
ENST00000583482.2
ENST00000583528.1
ENST00000583463.1
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_+_46926326 0.16 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr3_-_197282821 0.16 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr3_-_185826286 0.16 ENST00000537818.1
ENST00000422039.1
ENST00000434744.1
ETV5
ets variant 5
chr19_+_8117636 0.15 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr1_+_206680879 0.15 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr17_-_79869340 0.15 ENST00000538936.2
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr17_-_42327236 0.15 ENST00000399246.2
AC003102.1
AC003102.1
chr6_+_24495067 0.15 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr5_+_139028510 0.15 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr14_-_36990354 0.15 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr16_-_11485922 0.15 ENST00000599216.1
CTD-3088G3.8
Protein LOC388210
chr5_+_61602055 0.14 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr2_-_160472952 0.14 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr5_+_139027877 0.14 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr5_-_73937244 0.14 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr17_-_7382834 0.14 ENST00000380599.4
ZBTB4
zinc finger and BTB domain containing 4
chr11_-_73309228 0.14 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr15_+_85291785 0.14 ENST00000560079.2
ZNF592
zinc finger protein 592
chr2_+_149402553 0.14 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr10_+_181418 0.14 ENST00000403354.1
ENST00000381607.4
ENST00000402736.1
ZMYND11
zinc finger, MYND-type containing 11
chr14_-_51297837 0.14 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr11_-_82782861 0.14 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr16_+_69958887 0.14 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr10_-_121356007 0.14 ENST00000369093.2
ENST00000436547.2
TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr1_+_87797351 0.14 ENST00000370542.1
LMO4
LIM domain only 4
chr1_-_153895377 0.14 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr3_+_179370517 0.13 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chrX_-_19905703 0.13 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr11_+_118307179 0.13 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A
lysine (K)-specific methyltransferase 2A

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.2 0.6 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.2 0.6 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2 0.8 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.6 GO:0035803 egg coat formation(GO:0035803)
0.1 0.5 GO:2001074 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.3 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.9 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 2.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.3 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:0033216 ferric iron import(GO:0033216)
0.0 0.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.8 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.9 GO:0035640 exploration behavior(GO:0035640)
0.0 1.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.3 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.5 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.6 GO:0061458 reproductive system development(GO:0061458)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 1.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 2.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 1.0 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.8 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.6 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.2 0.8 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.5 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC