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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for KLF3

Z-value: 0.93

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Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
KLF3
ENSG00000109787.8 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_386658270.222.4e-01Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_7013897 2.85 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr2_+_172378757 2.35 ENST00000409484.1
ENST00000321348.4
ENST00000375252.3
CYBRD1
cytochrome b reductase 1
chr1_+_38022572 2.20 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr16_+_618837 1.88 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr1_-_42921915 1.88 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chrX_+_152338301 1.86 ENST00000453825.2
PNMA6A
paraneoplastic Ma antigen family member 6A
chr16_+_84209539 1.80 ENST00000569735.1
DNAAF1
dynein, axonemal, assembly factor 1
chr22_-_50970506 1.78 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr11_-_5248294 1.72 ENST00000335295.4
HBB
hemoglobin, beta
chr1_-_60539405 1.70 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr1_-_60539422 1.67 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr1_-_162838551 1.61 ENST00000367910.1
ENST00000367912.2
ENST00000367911.2
C1orf110
chromosome 1 open reading frame 110
chr3_-_50383096 1.59 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr21_-_35883613 1.45 ENST00000337385.3
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr20_-_3762087 1.43 ENST00000379756.3
SPEF1
sperm flagellar 1
chr19_+_4639514 1.32 ENST00000327473.4
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr11_+_86085778 1.27 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81
coiled-coil domain containing 81
chr21_-_35883541 1.24 ENST00000399284.1
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr1_-_75139397 1.22 ENST00000326665.5
C1orf173
chromosome 1 open reading frame 173
chr7_+_73245193 1.20 ENST00000340958.2
CLDN4
claudin 4
chr11_+_111789580 1.20 ENST00000278601.5
C11orf52
chromosome 11 open reading frame 52
chr11_-_5462744 1.16 ENST00000380211.1
OR51I1
olfactory receptor, family 51, subfamily I, member 1
chr5_-_54468974 1.15 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr19_+_917287 1.14 ENST00000592648.1
ENST00000234371.5
KISS1R
KISS1 receptor
chr22_-_50970566 1.13 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr1_-_159869912 1.08 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr16_+_2079501 1.05 ENST00000563587.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr4_-_75719896 1.01 ENST00000395743.3
BTC
betacellulin
chr7_-_99573677 0.99 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr4_-_87374283 0.97 ENST00000361569.2
MAPK10
mitogen-activated protein kinase 10
chr16_-_30125177 0.96 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr11_-_414948 0.92 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr20_+_36531499 0.92 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L
V-set and transmembrane domain containing 2 like
chr19_+_15751689 0.92 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr17_+_1633755 0.92 ENST00000545662.1
WDR81
WD repeat domain 81
chr17_+_73089382 0.88 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr5_+_75699149 0.88 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr7_+_29603394 0.87 ENST00000319694.2
PRR15
proline rich 15
chr19_+_17337406 0.87 ENST00000597836.1
OCEL1
occludin/ELL domain containing 1
chr11_-_72432950 0.87 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_-_38806390 0.87 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr21_-_47738112 0.87 ENST00000417060.1
C21orf58
chromosome 21 open reading frame 58
chr10_+_96443204 0.86 ENST00000339022.5
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr10_+_134145735 0.85 ENST00000368613.4
LRRC27
leucine rich repeat containing 27
chr5_-_40755987 0.84 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr6_-_32498046 0.83 ENST00000374975.3
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr22_+_31523734 0.83 ENST00000402238.1
ENST00000404453.1
ENST00000401755.1
INPP5J
inositol polyphosphate-5-phosphatase J
chr10_+_71211212 0.82 ENST00000373290.2
TSPAN15
tetraspanin 15
chr17_-_42019836 0.81 ENST00000225992.3
PPY
pancreatic polypeptide
chr4_-_168155730 0.81 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_+_2083265 0.80 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr6_-_33048483 0.79 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr3_+_186648307 0.75 ENST00000457772.2
ENST00000455441.1
ENST00000427315.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_-_38806540 0.75 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr3_+_51976338 0.74 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
PARP3
poly (ADP-ribose) polymerase family, member 3
chr3_+_106959530 0.72 ENST00000466734.1
ENST00000463143.1
ENST00000490441.1
LINC00883
long intergenic non-protein coding RNA 883
chr11_-_119252359 0.71 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr16_-_3086927 0.71 ENST00000572449.1
CCDC64B
coiled-coil domain containing 64B
chr2_-_27851843 0.71 ENST00000324364.3
CCDC121
coiled-coil domain containing 121
chr11_-_119252425 0.70 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr19_-_3025614 0.69 ENST00000447365.2
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr10_-_102089729 0.68 ENST00000465680.2
PKD2L1
polycystic kidney disease 2-like 1
chr16_-_1020849 0.68 ENST00000568897.1
LMF1
lipase maturation factor 1
chr20_+_34204939 0.68 ENST00000454819.1
SPAG4
sperm associated antigen 4
chr2_+_27237615 0.67 ENST00000458529.1
ENST00000402218.1
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr1_+_114471809 0.67 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr19_+_44081344 0.67 ENST00000599207.1
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr11_-_65793948 0.65 ENST00000312106.5
CATSPER1
cation channel, sperm associated 1
chr1_+_210406121 0.64 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr19_-_38806560 0.63 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr8_+_79578282 0.62 ENST00000263849.4
ZC2HC1A
zinc finger, C2HC-type containing 1A
chr9_-_86571628 0.61 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr22_-_31536480 0.59 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr4_-_168155700 0.58 ENST00000357545.4
ENST00000512648.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr15_-_101084446 0.58 ENST00000538112.2
ENST00000559639.1
ENST00000558884.2
CERS3
ceramide synthase 3
chr15_-_101084547 0.57 ENST00000394113.1
CERS3
ceramide synthase 3
chr4_-_168155417 0.56 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_+_17337027 0.56 ENST00000601529.1
ENST00000600232.1
OCEL1
occludin/ELL domain containing 1
chr7_+_100612904 0.56 ENST00000379442.3
ENST00000536621.1
MUC12
mucin 12, cell surface associated
chr7_+_33169142 0.56 ENST00000242067.6
ENST00000350941.3
ENST00000396127.2
ENST00000355070.2
ENST00000354265.4
ENST00000425508.2
BBS9
Bardet-Biedl syndrome 9
chr9_-_130637244 0.56 ENST00000373156.1
AK1
adenylate kinase 1
chr16_+_89894875 0.56 ENST00000393062.2
SPIRE2
spire-type actin nucleation factor 2
chr2_+_217498105 0.56 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr3_+_54156570 0.55 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chrX_-_13956737 0.54 ENST00000454189.2
GPM6B
glycoprotein M6B
chr3_+_20081515 0.54 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr19_+_17337007 0.53 ENST00000215061.4
OCEL1
occludin/ELL domain containing 1
chr6_-_31651817 0.53 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr14_-_21491305 0.53 ENST00000554531.1
NDRG2
NDRG family member 2
chr7_+_65670186 0.52 ENST00000304842.5
ENST00000442120.1
TPST1
tyrosylprotein sulfotransferase 1
chr19_+_15752088 0.52 ENST00000585846.1
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr1_+_6511651 0.52 ENST00000434576.1
ESPN
espin
chr19_+_14492247 0.52 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97
CD97 molecule
chr14_-_92333873 0.52 ENST00000435962.2
TC2N
tandem C2 domains, nuclear
chr3_-_170744498 0.52 ENST00000382808.4
ENST00000314251.3
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr6_+_43968306 0.51 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr1_+_44457261 0.51 ENST00000372318.3
CCDC24
coiled-coil domain containing 24
chr1_+_114471972 0.51 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr12_-_10151773 0.50 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr19_-_35992780 0.49 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr15_+_43885252 0.49 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr7_+_73703728 0.48 ENST00000361545.5
ENST00000223398.6
CLIP2
CAP-GLY domain containing linker protein 2
chr17_-_63822563 0.48 ENST00000317442.8
CEP112
centrosomal protein 112kDa
chr3_-_122512619 0.48 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr7_-_102184083 0.48 ENST00000379357.5
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr6_-_20212630 0.48 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr19_-_51529849 0.48 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr21_-_38445470 0.47 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_-_10450328 0.46 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr22_+_39760130 0.46 ENST00000381535.4
SYNGR1
synaptogyrin 1
chr15_+_43985084 0.45 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr19_-_10450287 0.44 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr21_-_38445297 0.44 ENST00000430792.1
ENST00000399103.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr11_+_537494 0.44 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr21_+_38445539 0.44 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr9_-_99382065 0.44 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
CDC14B
cell division cycle 14B
chr14_-_21491477 0.44 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG2
NDRG family member 2
chr11_+_111169976 0.44 ENST00000398035.2
COLCA2
colorectal cancer associated 2
chr3_-_10052763 0.44 ENST00000383808.2
ENST00000426698.1
ENST00000470827.2
AC022007.5
EMC3
AC022007.5
ER membrane protein complex subunit 3
chrX_+_38420623 0.43 ENST00000378482.2
TSPAN7
tetraspanin 7
chr6_-_28303901 0.43 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
ZSCAN31
zinc finger and SCAN domain containing 31
chr3_-_58196688 0.43 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr2_+_98330009 0.42 ENST00000264972.5
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr16_-_2379688 0.42 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr22_+_35776828 0.42 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr10_+_134145614 0.42 ENST00000368615.3
ENST00000392638.2
ENST00000344079.5
ENST00000356571.4
ENST00000368614.3
LRRC27
leucine rich repeat containing 27
chr19_+_36157715 0.42 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr17_-_61517572 0.42 ENST00000582997.1
CYB561
cytochrome b561
chr9_-_114361665 0.42 ENST00000309195.5
PTGR1
prostaglandin reductase 1
chr2_+_211342432 0.42 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr4_-_68411275 0.41 ENST00000273853.6
CENPC
centromere protein C
chr14_-_21492113 0.41 ENST00000554094.1
NDRG2
NDRG family member 2
chr14_-_21492251 0.41 ENST00000554398.1
NDRG2
NDRG family member 2
chr15_+_40643227 0.41 ENST00000448599.2
PHGR1
proline/histidine/glycine-rich 1
chr8_-_10512569 0.40 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr16_+_67233412 0.40 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr3_-_142166796 0.40 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chrX_-_101397433 0.40 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr19_+_1067271 0.40 ENST00000536472.1
ENST00000590214.1
HMHA1
histocompatibility (minor) HA-1
chr7_+_107384579 0.39 ENST00000222597.2
ENST00000415884.2
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr16_+_67207872 0.39 ENST00000563258.1
ENST00000568146.1
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr12_-_86230315 0.39 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chrX_-_71526741 0.39 ENST00000454225.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr16_+_84209738 0.38 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr7_-_99332719 0.38 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr12_-_57634475 0.38 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr7_-_102283238 0.37 ENST00000340457.8
UPK3BL
uroplakin 3B-like
chr16_-_1020954 0.37 ENST00000543238.1
ENST00000539379.1
ENST00000399843.2
ENST00000262301.11
LMF1
lipase maturation factor 1
chr11_+_1874200 0.37 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr16_+_67207838 0.36 ENST00000566871.1
ENST00000268605.7
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr6_-_41254403 0.36 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
TREM1
triggering receptor expressed on myeloid cells 1
chr1_+_23695680 0.36 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213
chromosome 1 open reading frame 213
chr15_-_52043722 0.36 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chrX_+_129473859 0.36 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr19_-_16008880 0.35 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr11_+_121447469 0.35 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr11_-_111783919 0.35 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr12_+_7169887 0.35 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr7_+_26191809 0.34 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr16_+_66878814 0.34 ENST00000394069.3
CA7
carbonic anhydrase VII
chr10_+_45495898 0.34 ENST00000298299.3
ZNF22
zinc finger protein 22
chr3_-_127542051 0.34 ENST00000398104.1
MGLL
monoglyceride lipase
chr17_+_73996987 0.33 ENST00000588812.1
ENST00000448471.1
CDK3
cyclin-dependent kinase 3
chr7_-_73153122 0.33 ENST00000458339.1
ABHD11
abhydrolase domain containing 11
chr4_-_168155577 0.33 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_+_206680879 0.32 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr15_-_61521495 0.32 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr6_+_130686856 0.32 ENST00000296978.3
TMEM200A
transmembrane protein 200A
chr5_+_140501581 0.32 ENST00000194152.1
PCDHB4
protocadherin beta 4
chr12_-_55378452 0.32 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr3_+_140396881 0.31 ENST00000286349.3
TRIM42
tripartite motif containing 42
chr17_+_72427477 0.31 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_-_155112883 0.31 ENST00000368399.1
ENST00000368400.4
ENST00000341298.3
DPM3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr22_+_42949925 0.31 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
SERHL2
serine hydrolase-like 2
chr7_-_73153161 0.31 ENST00000395147.4
ABHD11
abhydrolase domain containing 11
chr7_+_872107 0.31 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
SUN1
Sad1 and UNC84 domain containing 1
chr19_-_40023450 0.31 ENST00000326282.4
EID2B
EP300 interacting inhibitor of differentiation 2B
chr11_-_114466471 0.31 ENST00000424261.2
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr12_-_56848426 0.31 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chrX_+_153029633 0.31 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
PLXNB3
plexin B3
chr11_-_114466477 0.30 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr14_-_50583271 0.30 ENST00000395860.2
ENST00000395859.2
VCPKMT
valosin containing protein lysine (K) methyltransferase
chr21_-_38445011 0.30 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_-_106773291 0.30 ENST00000343245.3
ATG5
autophagy related 5
chr21_-_38445443 0.30 ENST00000360525.4
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr11_+_75428857 0.30 ENST00000198801.5
MOGAT2
monoacylglycerol O-acyltransferase 2
chr7_-_73153178 0.30 ENST00000437775.2
ENST00000222800.3
ABHD11
abhydrolase domain containing 11
chr6_-_106773610 0.30 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chr1_+_207494853 0.30 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr3_+_101443476 0.30 ENST00000327230.4
ENST00000494050.1
CEP97
centrosomal protein 97kDa
chr1_+_18434240 0.30 ENST00000251296.1
IGSF21
immunoglobin superfamily, member 21
chrX_+_48681768 0.30 ENST00000430858.1
HDAC6
histone deacetylase 6
chr6_-_106773491 0.30 ENST00000360666.4
ATG5
autophagy related 5
chr13_-_33002279 0.29 ENST00000380130.2
N4BP2L1
NEDD4 binding protein 2-like 1
chr9_+_100174344 0.29 ENST00000422139.2
TDRD7
tudor domain containing 7
chr20_+_49348081 0.29 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr1_+_44401479 0.29 ENST00000438616.3
ARTN
artemin
chr12_+_12878829 0.29 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr19_+_8455200 0.29 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr2_-_136743169 0.28 ENST00000264161.4
DARS
aspartyl-tRNA synthetase

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0030185 nitric oxide transport(GO:0030185)
0.4 2.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.3 1.8 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.3 1.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 0.8 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2 0.7 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 2.9 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.2 1.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.9 GO:2000619 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.1 3.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.4 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.9 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 1.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.9 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.4 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 1.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 1.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 0.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 1.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.4 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 2.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.7 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.1 0.4 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 1.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.1 1.4 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.3 GO:0044691 tooth eruption(GO:0044691)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:0006366 transcription from RNA polymerase II promoter(GO:0006366)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.1 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.3 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.3 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.3 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.5 GO:0071104 response to interleukin-9(GO:0071104)
0.1 0.4 GO:2000561 CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 1.0 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.3 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.3 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 1.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847) negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.6 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 1.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 2.0 GO:0010039 response to iron ion(GO:0010039)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.2 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0043366 beta selection(GO:0043366)
0.0 0.2 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.4 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.6 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.6 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.1 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0071493 elastic fiber assembly(GO:0048251) cellular response to UV-B(GO:0071493)
0.0 1.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 1.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.0 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0090196 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 3.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 1.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 2.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.5 GO:0000125 PCAF complex(GO:0000125)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 5.6 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.5 2.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.3 3.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 2.7 GO:0031433 telethonin binding(GO:0031433)
0.2 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.4 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 0.4 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 2.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.8 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.7 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 1.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 1.2 GO:0070330 aromatase activity(GO:0070330)
0.1 1.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 1.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.8 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade