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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for KLF6

Z-value: 1.05

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Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
ENSG00000067082.10 Kruppel like factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827417_3827473-0.478.1e-03Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_67465016 4.16 ENST00000326152.5
hydroxysteroid (11-beta) dehydrogenase 2
chr6_-_29595779 3.68 ENST00000355973.3
ENST00000377012.4
gamma-aminobutyric acid (GABA) B receptor, 1
chr13_+_35516390 3.05 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
neurobeachin
chr6_+_19837592 2.78 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr7_+_106685079 2.75 ENST00000265717.4
protein kinase, cAMP-dependent, regulatory, type II, beta
chr17_-_42277203 2.54 ENST00000587097.1
ataxin 7-like 3
chr16_+_69600209 2.34 ENST00000566899.1
nuclear factor of activated T-cells 5, tonicity-responsive
chr19_+_45504688 2.16 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr16_+_69599861 2.05 ENST00000354436.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr16_+_69599899 1.83 ENST00000567239.1
nuclear factor of activated T-cells 5, tonicity-responsive
chr8_-_110656995 1.55 ENST00000276646.9
ENST00000533065.1
syntabulin (syntaxin-interacting)
chr16_+_69600058 1.54 ENST00000393742.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr6_+_24495067 1.52 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr11_+_45907177 1.46 ENST00000241014.2
mitogen-activated protein kinase 8 interacting protein 1
chr1_+_151254738 1.41 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
zinc finger protein 687
chr3_-_19988462 1.41 ENST00000344838.4
EF-hand domain family, member B
chr12_-_112450915 1.41 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
transmembrane protein 116
chr9_-_37465396 1.39 ENST00000307750.4
zinc finger and BTB domain containing 5
chr3_-_113415441 1.37 ENST00000491165.1
ENST00000316407.4
KIAA2018
chr17_-_7145475 1.34 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABA(A) receptor-associated protein
chr11_+_71238313 1.33 ENST00000398536.4
keratin associated protein 5-7
chr10_+_45869652 1.18 ENST00000542434.1
ENST00000374391.2
arachidonate 5-lipoxygenase
chr5_+_42423872 1.14 ENST00000230882.4
ENST00000357703.3
growth hormone receptor
chr11_-_108464465 1.11 ENST00000525344.1
exophilin 5
chr3_-_121740969 1.10 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
immunoglobulin-like domain containing receptor 1
chr2_-_27603582 1.10 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr15_-_75743915 1.06 ENST00000394949.4
SIN3 transcription regulator family member A
chr1_+_87797351 1.04 ENST00000370542.1
LIM domain only 4
chr22_-_17602143 1.04 ENST00000331437.3
cat eye syndrome chromosome region, candidate 6
chr6_+_17281573 1.02 ENST00000379052.5
RNA binding motif protein 24
chr17_-_7120498 1.00 ENST00000485100.1
discs, large homolog 4 (Drosophila)
chr1_-_227505289 1.00 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr19_-_40931891 0.95 ENST00000357949.4
SERTA domain containing 1
chr5_-_107717058 0.94 ENST00000359660.5
F-box and leucine-rich repeat protein 17
chr1_+_151693984 0.94 ENST00000479191.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr6_+_32811885 0.93 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr6_+_36164487 0.93 ENST00000357641.6
bromodomain and PHD finger containing, 3
chr7_+_128828713 0.93 ENST00000249373.3
smoothened, frizzled family receptor
chr22_-_17602200 0.93 ENST00000399875.1
cat eye syndrome chromosome region, candidate 6
chr1_-_236445251 0.92 ENST00000354619.5
ENST00000327333.8
ERO1-like beta (S. cerevisiae)
chr2_-_73460334 0.91 ENST00000258083.2
protease-associated domain containing 1
chr9_-_130742792 0.91 ENST00000373095.1
family with sequence similarity 102, member A
chr10_+_76586348 0.91 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr11_-_108464321 0.91 ENST00000265843.4
exophilin 5
chr19_+_8455200 0.91 ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr17_-_1928621 0.90 ENST00000331238.6
reticulon 4 receptor-like 1
chr1_+_6845497 0.90 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr11_+_64009072 0.89 ENST00000535135.1
ENST00000394540.3
FK506 binding protein 2, 13kDa
chr1_-_182361327 0.88 ENST00000331872.6
ENST00000311223.5
glutamate-ammonia ligase
chr8_-_101321584 0.88 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr6_-_33285505 0.88 ENST00000431845.2
zinc finger and BTB domain containing 22
chr20_+_48807351 0.87 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr7_-_72936608 0.85 ENST00000404251.1
bromodomain adjacent to zinc finger domain, 1B
chr3_+_49449636 0.82 ENST00000273590.3
T-cell leukemia translocation altered
chr2_-_220436248 0.82 ENST00000265318.4
obscurin-like 1
chr16_-_49315731 0.82 ENST00000219197.6
cerebellin 1 precursor
chr4_+_26862400 0.81 ENST00000467011.1
ENST00000412829.2
stromal interaction molecule 2
chr19_-_47734448 0.80 ENST00000439096.2
BCL2 binding component 3
chr8_-_101322132 0.80 ENST00000523481.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr1_-_182360498 0.79 ENST00000417584.2
glutamate-ammonia ligase
chr11_+_45918092 0.78 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr22_-_38484922 0.78 ENST00000428572.1
BAI1-associated protein 2-like 2
chr19_-_55691472 0.77 ENST00000537500.1
synaptotagmin V
chr2_+_85766280 0.77 ENST00000306434.3
methionine adenosyltransferase II, alpha
chr17_-_42276574 0.76 ENST00000589805.1
ataxin 7-like 3
chr7_-_99774945 0.75 ENST00000292377.2
glypican 2
chr1_-_182360918 0.75 ENST00000339526.4
glutamate-ammonia ligase
chr19_-_55691614 0.74 ENST00000592470.1
ENST00000354308.3
synaptotagmin V
chr2_-_219433014 0.74 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr12_+_72233487 0.73 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1 domain family, member 15
chr1_-_23670817 0.73 ENST00000478691.1
heterogeneous nuclear ribonucleoprotein R
chr6_-_32811771 0.73 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr10_+_124768482 0.72 ENST00000368869.4
ENST00000358776.4
acyl-CoA dehydrogenase, short/branched chain
chr17_+_53342311 0.72 ENST00000226067.5
hepatic leukemia factor
chr20_-_40247133 0.72 ENST00000373233.3
ENST00000309279.7
chromodomain helicase DNA binding protein 6
chr9_-_95896550 0.72 ENST00000375446.4
ninjurin 1
chr11_-_72492903 0.72 ENST00000537947.1
StAR-related lipid transfer (START) domain containing 10
chr3_-_50540854 0.71 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr15_-_75744014 0.71 ENST00000394947.3
ENST00000565264.1
SIN3 transcription regulator family member A
chr13_-_45010939 0.71 ENST00000261489.2
TSC22 domain family, member 1
chr17_-_7120525 0.71 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
discs, large homolog 4 (Drosophila)
chr3_-_88108192 0.70 ENST00000309534.6
CGG triplet repeat binding protein 1
chr1_+_21835858 0.69 ENST00000539907.1
ENST00000540617.1
ENST00000374840.3
alkaline phosphatase, liver/bone/kidney
chr17_+_30264014 0.69 ENST00000322652.5
ENST00000580398.1
SUZ12 polycomb repressive complex 2 subunit
chr8_+_67976593 0.69 ENST00000262210.5
ENST00000412460.1
centrosome and spindle pole associated protein 1
chr17_-_42298201 0.69 ENST00000527034.1
upstream binding transcription factor, RNA polymerase I
chr12_+_124196865 0.68 ENST00000330342.3
ATPase, H+ transporting, lysosomal V0 subunit a2
chr17_-_79008373 0.67 ENST00000577066.1
ENST00000573167.1
BAIAP2 antisense RNA 1 (head to head)
chr4_+_88928777 0.67 ENST00000237596.2
polycystic kidney disease 2 (autosomal dominant)
chr11_+_57365150 0.67 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr5_+_67511524 0.66 ENST00000521381.1
ENST00000521657.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_26862431 0.66 ENST00000465503.1
stromal interaction molecule 2
chr16_-_68482440 0.66 ENST00000219334.5
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr20_-_21378666 0.65 ENST00000351817.4
NK2 homeobox 4
chr1_-_227505826 0.65 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42 binding protein kinase alpha (DMPK-like)
chr1_+_43148059 0.65 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr19_+_48673949 0.65 ENST00000328759.7
chromosome 19 open reading frame 68
chr17_+_2240916 0.65 ENST00000574563.1
small G protein signaling modulator 2
chr6_+_32811861 0.64 ENST00000453426.1
TAP1 and PSMB8 antisense RNA 1
chr1_-_169455169 0.64 ENST00000367804.4
ENST00000236137.5
solute carrier family 19 (thiamine transporter), member 2
chr14_-_39901618 0.64 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr19_-_11456905 0.63 ENST00000588560.1
ENST00000592952.1
transmembrane protein 205
chr3_+_88108381 0.63 ENST00000473136.1
Uncharacterized protein
chr1_+_33722080 0.63 ENST00000483388.1
ENST00000539719.1
zinc finger protein 362
chr12_+_56473628 0.63 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_+_110152033 0.62 ENST00000538780.1
family with sequence similarity 222, member A
chr11_+_65479462 0.62 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
K(lysine) acetyltransferase 5
chr22_+_31608219 0.61 ENST00000406516.1
ENST00000444929.2
ENST00000331728.4
LIM domain kinase 2
chr11_+_64008525 0.61 ENST00000449942.2
FK506 binding protein 2, 13kDa
chr11_-_133826852 0.61 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr11_+_68228186 0.61 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
protein phosphatase 6, regulatory subunit 3
chr14_-_21945057 0.61 ENST00000397762.1
RAB2B, member RAS oncogene family
chr12_+_52445191 0.61 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4, group A, member 1
chr21_+_43639211 0.60 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr19_-_10764509 0.60 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr14_+_89029253 0.60 ENST00000251038.5
ENST00000359301.3
ENST00000302216.8
zinc finger CCCH-type containing 14
chr14_-_23770683 0.60 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
protein phosphatase 1, regulatory subunit 3E
chr15_-_45480153 0.60 ENST00000560471.1
ENST00000560540.1
Src homology 2 domain containing F
chr17_-_80231557 0.59 ENST00000392334.2
ENST00000314028.6
casein kinase 1, delta
chr1_+_36023035 0.59 ENST00000373253.3
neurochondrin
chr13_-_41768654 0.59 ENST00000379483.3
kelch repeat and BTB (POZ) domain containing 7
chr18_+_60190226 0.58 ENST00000269499.5
zinc finger, CCHC domain containing 2
chr1_+_6845578 0.58 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr19_-_11456872 0.58 ENST00000586218.1
transmembrane protein 205
chr1_-_23670813 0.58 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr3_-_141868357 0.57 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
transcription factor Dp-2 (E2F dimerization partner 2)
chr22_-_30783075 0.57 ENST00000215798.6
ring finger protein 215
chr12_+_112451120 0.57 ENST00000261735.3
ENST00000455836.1
endoplasmic reticulum protein 29
chr2_-_97405775 0.57 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
lectin, mannose-binding 2-like
chr1_+_40839369 0.57 ENST00000372718.3
small ArfGAP2
chr4_+_26862313 0.56 ENST00000467087.1
ENST00000382009.3
ENST00000237364.5
stromal interaction molecule 2
chr1_-_165324983 0.55 ENST00000367893.4
LIM homeobox transcription factor 1, alpha
chr1_-_35395178 0.55 ENST00000373347.1
discs, large (Drosophila) homolog-associated protein 3
chr15_+_43803143 0.55 ENST00000382031.1
microtubule-associated protein 1A
chr1_+_156698234 0.55 ENST00000368218.4
ENST00000368216.4
ribosomal RNA adenine dimethylase domain containing 1
chr5_-_159739532 0.54 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
cyclin J-like
chr1_-_23670752 0.54 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chrX_+_40944871 0.54 ENST00000378308.2
ENST00000324545.8
ubiquitin specific peptidase 9, X-linked
chr19_-_5978144 0.54 ENST00000340578.6
ENST00000541471.1
ENST00000591736.1
ENST00000587479.1
RAN binding protein 3
chr11_-_72492878 0.53 ENST00000535054.1
ENST00000545082.1
StAR-related lipid transfer (START) domain containing 10
chr19_+_50094866 0.53 ENST00000418929.2
proline rich 12
chr9_-_6007787 0.53 ENST00000399933.3
ENST00000381461.2
ENST00000513355.2
KIAA2026
chr13_+_88324870 0.53 ENST00000325089.6
SLIT and NTRK-like family, member 5
chr1_+_114472481 0.53 ENST00000369555.2
homeodomain interacting protein kinase 1
chr8_+_74206829 0.52 ENST00000240285.5
retinol dehydrogenase 10 (all-trans)
chr1_+_113615794 0.52 ENST00000361127.5
leucine-rich repeats and immunoglobulin-like domains 2
chr19_-_5978090 0.52 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RAN binding protein 3
chr5_-_81046904 0.52 ENST00000515395.1
single-stranded DNA binding protein 2
chr6_+_21593972 0.51 ENST00000244745.1
ENST00000543472.1
SRY (sex determining region Y)-box 4
chr2_+_24714729 0.51 ENST00000406961.1
ENST00000405141.1
nuclear receptor coactivator 1
chr2_+_74781828 0.51 ENST00000340004.6
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr1_-_114302086 0.50 ENST00000369604.1
ENST00000357783.2
putative homeodomain transcription factor 1
chr6_-_31697563 0.50 ENST00000375789.2
ENST00000416410.1
dimethylarginine dimethylaminohydrolase 2
chr10_+_70587279 0.50 ENST00000298596.6
ENST00000399169.4
ENST00000399165.4
ENST00000399162.2
storkhead box 1
chr1_-_114301960 0.50 ENST00000369598.1
ENST00000369600.1
putative homeodomain transcription factor 1
chr14_+_93897272 0.49 ENST00000393151.2
unc-79 homolog (C. elegans)
chr15_+_96873921 0.49 ENST00000394166.3
nuclear receptor subfamily 2, group F, member 2
chr5_+_56111361 0.49 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr3_-_53080047 0.48 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chr12_+_10365404 0.48 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr1_-_154531095 0.48 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_35227449 0.48 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
zinc finger protein 76
chr1_-_156051789 0.48 ENST00000532414.2
mex-3 RNA binding family member A
chr19_+_50084561 0.48 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr20_+_35201857 0.48 ENST00000373874.2
TGFB-induced factor homeobox 2
chr6_-_137113604 0.48 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr1_+_114472222 0.46 ENST00000369558.1
ENST00000369561.4
homeodomain interacting protein kinase 1
chr15_+_44084040 0.46 ENST00000249786.4
small EDRK-rich factor 2
chr2_-_71454185 0.46 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr6_+_52442083 0.46 ENST00000606714.1
TRAM2 antisense RNA 1 (head to head)
chr2_+_10442993 0.45 ENST00000423674.1
ENST00000307845.3
hippocalcin-like 1
chr15_-_43882353 0.45 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
diphosphoinositol pentakisphosphate kinase 1
chr2_-_97535708 0.45 ENST00000305476.5
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr20_+_60813535 0.45 ENST00000358053.2
ENST00000313733.3
ENST00000439951.2
oxysterol binding protein-like 2
chr3_-_88108212 0.45 ENST00000482016.1
CGG triplet repeat binding protein 1
chr5_+_56469843 0.44 ENST00000514387.2
GC-rich promoter binding protein 1
chrX_-_128788914 0.44 ENST00000429967.1
ENST00000307484.6
apelin
chr5_-_81046841 0.44 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
single-stranded DNA binding protein 2
chr4_-_36246060 0.44 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_83777374 0.43 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr5_+_56469939 0.43 ENST00000506184.2
GC-rich promoter binding protein 1
chr2_+_42275153 0.43 ENST00000294964.5
protein kinase domain containing, cytoplasmic
chr1_+_6845384 0.43 ENST00000303635.7
calmodulin binding transcription activator 1
chr2_+_111878483 0.43 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2-like 11 (apoptosis facilitator)
chr12_-_50222187 0.43 ENST00000335999.6
NCK-associated protein 5-like
chr15_-_72410109 0.43 ENST00000564571.1
myosin IXA
chr17_-_7518145 0.42 ENST00000250113.7
ENST00000571597.1
fragile X mental retardation, autosomal homolog 2
chr12_-_96184533 0.42 ENST00000343702.4
ENST00000344911.4
netrin 4
chrX_+_152990302 0.41 ENST00000218104.3
ATP-binding cassette, sub-family D (ALD), member 1
chr5_+_56469775 0.41 ENST00000424459.3
GC-rich promoter binding protein 1
chr17_-_27278304 0.41 ENST00000577226.1
PHD finger protein 12
chr17_+_36861735 0.40 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr6_-_143266297 0.40 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr15_-_56035177 0.40 ENST00000389286.4
ENST00000561292.1
protogenin
chr11_+_117070037 0.40 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
transgelin
chr7_+_90225796 0.40 ENST00000380050.3
cyclin-dependent kinase 14
chr2_+_232573222 0.40 ENST00000341369.7
ENST00000409683.1
prothymosin, alpha
chr9_-_130517522 0.40 ENST00000373274.3
ENST00000420366.1
SH2 domain containing 3C
chr15_-_83316254 0.40 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr3_-_47205457 0.39 ENST00000409792.3
SET domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.6 2.8 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.5 2.0 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.4 2.7 GO:0097338 response to clozapine(GO:0097338)
0.3 1.3 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.3 5.0 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.3 2.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3 1.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 2.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 0.8 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.3 1.5 GO:0006540 acetate metabolic process(GO:0006083) glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 0.7 GO:0071529 cementum mineralization(GO:0071529)
0.2 8.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 0.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.9 GO:0072093 positive regulation of hh target transcription factor activity(GO:0007228) ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) metanephric renal vesicle formation(GO:0072093)
0.2 1.7 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.2 0.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 0.5 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.6 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 0.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 1.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.6 GO:0043335 protein unfolding(GO:0043335)
0.1 0.8 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 2.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.5 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 1.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.5 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.1 1.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 3.4 GO:0016578 histone deubiquitination(GO:0016578)
0.1 2.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 1.2 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.7 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0097676 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.1 4.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.3 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.4 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.4 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.5 GO:0060431 primary lung bud formation(GO:0060431)
0.1 1.0 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 1.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 0.6 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 1.3 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 0.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.7 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.7 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.7 GO:0042048 olfactory behavior(GO:0042048)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.6 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:0060988 lipid tube assembly(GO:0060988)
0.1 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.8 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0006014 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.7 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.7 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0015840 urea transport(GO:0015840) urinary bladder development(GO:0060157)
0.0 0.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 1.8 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.3 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.2 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 2.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.5 GO:0007625 grooming behavior(GO:0007625)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390) positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.4 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.2 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.6 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.5 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 1.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.7 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 1.9 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 1.0 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.0 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0036514 dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.5 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.6 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.2 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.3 GO:0097120 receptor localization to synapse(GO:0097120)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 1.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.3 1.5 GO:1990769 proximal neuron projection(GO:1990769)
0.3 2.2 GO:0044294 dendritic growth cone(GO:0044294)
0.3 1.0 GO:0005667 transcription factor complex(GO:0005667)
0.3 0.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 3.3 GO:0000124 SAGA complex(GO:0000124)
0.2 2.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 2.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 0.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.1 1.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 2.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.1 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.6 GO:0097433 dense body(GO:0097433)
0.1 0.8 GO:1990393 3M complex(GO:1990393)
0.1 1.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.4 GO:0097386 glial cell projection(GO:0097386)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 1.7 GO:0042641 actomyosin(GO:0042641)
0.1 1.3 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 1.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.8 GO:0071439 clathrin complex(GO:0071439)
0.0 0.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 2.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.5 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.9 3.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 2.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.6 1.7 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.4 1.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 0.6 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 0.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 2.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 0.7 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.1 1.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 2.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 2.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.7 GO:0043559 insulin binding(GO:0043559)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 4.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 2.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.8 GO:0051117 ATPase binding(GO:0051117)
0.0 1.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.5 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 2.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 7.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 1.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0052723 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.0 GO:0097677 STAT family protein binding(GO:0097677)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 3.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.3 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 2.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 1.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 4.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS