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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for KLF7

Z-value: 0.21

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Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
ENSG00000118263.10 Kruppel like factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF7hg19_v2_chr2_-_208030647_2080306890.125.4e-01Click!

Activity profile of KLF7 motif

Sorted Z-values of KLF7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_186353756 0.46 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
fetuin B
chr15_+_92937058 0.16 ENST00000268164.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr8_+_72587535 0.15 ENST00000519840.1
ENST00000521131.1
RP11-1144P22.1
chr1_-_21948906 0.15 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr8_-_6837602 0.14 ENST00000382692.2
defensin, alpha 1
chr15_+_92937144 0.13 ENST00000539113.1
ENST00000555434.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr16_+_31539197 0.13 ENST00000564707.1
alpha hemoglobin stabilizing protein
chr8_-_6875778 0.12 ENST00000535841.1
ENST00000327857.2
defensin, alpha 1B
defensin, alpha 3, neutrophil-specific
chr19_-_7694417 0.12 ENST00000358368.4
ENST00000534844.1
XPA binding protein 2
chr19_+_39390320 0.11 ENST00000576510.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr16_+_11439286 0.09 ENST00000312499.5
ENST00000576027.1
RecQ mediated genome instability 2
chr3_-_105587879 0.08 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_+_81772633 0.07 ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
ENST00000565054.1
RP11-960L18.1
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr5_+_173315283 0.06 ENST00000265085.5
cytoplasmic polyadenylation element binding protein 4
chr19_+_39390587 0.06 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr1_-_157108266 0.05 ENST00000326786.4
ets variant 3
chr6_+_30585486 0.05 ENST00000259873.4
ENST00000506373.2
mitochondrial ribosomal protein S18B
chr5_+_176560007 0.05 ENST00000510954.1
ENST00000354179.4
nuclear receptor binding SET domain protein 1
chr8_+_17104539 0.04 ENST00000521829.1
ENST00000521005.1
vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr2_+_97779233 0.04 ENST00000461153.2
ENST00000420699.2
ankyrin repeat domain 36
chr13_-_108867101 0.04 ENST00000356922.4
ligase IV, DNA, ATP-dependent
chr6_-_109703600 0.04 ENST00000512821.1
CD164 molecule, sialomucin
chr6_-_109703634 0.04 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164 molecule, sialomucin
chr1_+_87380299 0.04 ENST00000370551.4
ENST00000370550.5
heparan sulfate 2-O-sulfotransferase 1
chr2_-_74710078 0.04 ENST00000290418.4
coiled-coil domain containing 142
chr1_-_19229248 0.04 ENST00000375341.3
aldehyde dehydrogenase 4 family, member A1
chr20_-_2821271 0.04 ENST00000448755.1
ENST00000360652.2
PC-esterase domain containing 1A
chr22_-_30987837 0.04 ENST00000335214.6
pescadillo ribosomal biogenesis factor 1
chr1_-_19229014 0.03 ENST00000538839.1
ENST00000290597.5
aldehyde dehydrogenase 4 family, member A1
chr6_-_109703663 0.03 ENST00000368961.5
CD164 molecule, sialomucin
chr1_-_21503337 0.03 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
eukaryotic translation initiation factor 4 gamma, 3
chr17_+_41476327 0.03 ENST00000320033.4
ADP-ribosylation factor-like 4D
chr20_-_2821756 0.03 ENST00000356872.3
ENST00000439542.1
PC-esterase domain containing 1A
chr3_-_33138624 0.03 ENST00000445488.2
ENST00000307377.8
ENST00000440656.1
ENST00000436768.1
ENST00000307363.5
galactosidase, beta 1
chr3_-_105588231 0.02 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_+_31539183 0.02 ENST00000302312.4
alpha hemoglobin stabilizing protein
chr19_-_40931891 0.02 ENST00000357949.4
SERTA domain containing 1
chr17_-_46894576 0.02 ENST00000393382.3
tubulin tyrosine ligase-like family, member 6
chr17_+_18218587 0.02 ENST00000406438.3
Smith-Magenis syndrome chromosome region, candidate 8
chr20_+_2821340 0.02 ENST00000380445.3
ENST00000380469.3
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr3_-_178865747 0.02 ENST00000435560.1
RP11-360P21.2
chr7_+_27779714 0.01 ENST00000265393.6
ENST00000409980.1
ENST00000433216.2
ENST00000396319.2
Tax1 (human T-cell leukemia virus type I) binding protein 1
chr19_-_39390440 0.01 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
sirtuin 2
chr22_-_30987849 0.01 ENST00000402284.3
ENST00000354694.7
pescadillo ribosomal biogenesis factor 1
chr1_-_161102367 0.01 ENST00000464113.1
death effector domain containing
chr6_-_33239612 0.01 ENST00000482399.1
ENST00000445902.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr19_-_39390350 0.01 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
sirtuin 2
chr6_+_43603552 0.01 ENST00000372171.4
MAD2L1 binding protein
chr19_+_7694623 0.01 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100 homolog (S. cerevisiae)
chr15_+_96873921 0.01 ENST00000394166.3
nuclear receptor subfamily 2, group F, member 2
chr17_-_4269768 0.01 ENST00000396981.2
ubiquitin-conjugating enzyme E2G 1
chr5_+_141348598 0.01 ENST00000394520.2
ENST00000347642.3
ring finger protein 14
chr6_+_33239787 0.01 ENST00000439602.2
ENST00000474973.1
ribosomal protein S18
chr5_+_141348721 0.00 ENST00000507163.1
ENST00000394519.1
ring finger protein 14
chr6_+_31865552 0.00 ENST00000469372.1
ENST00000497706.1
complement component 2
chr19_-_14629224 0.00 ENST00000254322.2
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_+_74710194 0.00 ENST00000410003.1
ENST00000442235.2
ENST00000233623.5
tetratricopeptide repeat domain 31
chr1_+_28157273 0.00 ENST00000311772.5
ENST00000236412.7
ENST00000373931.4
protein phosphatase 1, regulatory subunit 8

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.0 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation