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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for LHX8

Z-value: 0.66

Motif logo

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Transcription factors associated with LHX8

Gene Symbol Gene ID Gene Info
LHX8
ENSG00000162624.10 LIM homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX8hg19_v2_chr1_+_75594119_75594119,
hg19_v2_chr1_+_75600567_75600567		-0.532.7e-03Click!

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_137028534 3.23 ENST00000348225.2
PTN
pleiotrophin
chr7_-_137028498 3.05 ENST00000393083.2
PTN
pleiotrophin
chr11_+_101918153 2.61 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr22_-_50970919 2.32 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr3_-_112693865 2.26 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1
CD200 receptor 1
chr12_-_71551652 2.26 ENST00000546561.1
TSPAN8
tetraspanin 8
chr16_-_53737795 2.02 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr12_-_71551868 2.01 ENST00000247829.3
TSPAN8
tetraspanin 8
chr16_-_53737722 2.00 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr3_-_151102529 1.97 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr4_-_110723134 1.80 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr3_-_112693759 1.75 ENST00000440122.2
ENST00000490004.1
CD200R1
CD200 receptor 1
chr8_+_99076750 1.73 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr4_-_110723194 1.73 ENST00000394635.3
CFI
complement factor I
chr8_+_17354617 1.65 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr4_-_110723335 1.56 ENST00000394634.2
CFI
complement factor I
chr3_+_100328433 1.36 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr8_+_99076509 1.34 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr22_+_23487513 1.32 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chrX_-_117119243 1.19 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr8_+_17354587 1.17 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr5_-_75008244 1.16 ENST00000510798.1
ENST00000446329.2
POC5
POC5 centriolar protein
chr5_+_140165876 1.13 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr1_-_48937838 1.07 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr6_+_116691001 1.01 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr12_+_64173583 1.00 ENST00000261234.6
TMEM5
transmembrane protein 5
chr7_-_120498357 0.96 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr9_-_20622478 0.92 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr19_-_9006766 0.88 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr16_-_88770019 0.86 ENST00000541206.2
RNF166
ring finger protein 166
chr11_+_125757556 0.83 ENST00000526028.1
HYLS1
hydrolethalus syndrome 1
chr19_+_827823 0.82 ENST00000233997.2
AZU1
azurocidin 1
chr3_+_119187785 0.81 ENST00000295588.4
ENST00000476573.1
POGLUT1
protein O-glucosyltransferase 1
chr5_-_41213607 0.78 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr1_-_236445251 0.77 ENST00000354619.5
ENST00000327333.8
ERO1LB
ERO1-like beta (S. cerevisiae)
chr1_-_247242048 0.75 ENST00000366503.2
ZNF670
zinc finger protein 670
chr7_+_114055052 0.72 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr2_-_152830479 0.71 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_-_48937821 0.70 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr1_-_217262933 0.66 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr6_+_29364416 0.66 ENST00000383555.2
OR12D2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr8_+_75262612 0.64 ENST00000220822.7
GDAP1
ganglioside induced differentiation associated protein 1
chr1_-_217262969 0.62 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr11_-_3400442 0.61 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chr10_+_90672113 0.61 ENST00000371922.1
STAMBPL1
STAM binding protein-like 1
chr2_+_114195268 0.60 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr11_+_60048004 0.59 ENST00000532114.1
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr3_-_52804872 0.59 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NEK4
NIMA-related kinase 4
chr4_+_74718906 0.59 ENST00000226524.3
PF4V1
platelet factor 4 variant 1
chr2_-_152830441 0.58 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr3_+_195447738 0.57 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr15_+_65843130 0.56 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr11_-_31531121 0.56 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_-_39734783 0.55 ENST00000552961.1
KIF21A
kinesin family member 21A
chr19_+_21688366 0.55 ENST00000358491.4
ENST00000597078.1
ZNF429
zinc finger protein 429
chr2_-_152118352 0.54 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr21_-_28820892 0.54 ENST00000420186.2
AP001604.3
AP001604.3
chr12_-_10766184 0.54 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
MAGOHB
mago-nashi homolog B (Drosophila)
chr2_+_216946589 0.53 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr16_+_67927147 0.51 ENST00000291041.5
PSKH1
protein serine kinase H1
chr19_+_44716678 0.50 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
ZNF227
zinc finger protein 227
chr4_+_71108300 0.50 ENST00000304954.3
CSN3
casein kappa
chr1_+_33722080 0.50 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr8_+_75262629 0.50 ENST00000434412.2
GDAP1
ganglioside induced differentiation associated protein 1
chr9_+_26956371 0.49 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr16_+_22217577 0.45 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr13_-_24895566 0.45 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr4_+_189060573 0.43 ENST00000332517.3
TRIML1
tripartite motif family-like 1
chr6_+_160221293 0.43 ENST00000610273.1
ENST00000392167.3
PNLDC1
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr12_-_88974236 0.42 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr11_-_68780824 0.42 ENST00000441623.1
ENST00000309099.6
MRGPRF
MAS-related GPR, member F
chr9_-_69262509 0.39 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr1_-_212004090 0.38 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chrX_+_108779870 0.37 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr10_+_135207598 0.37 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr19_-_10305752 0.37 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr9_-_179018 0.37 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr5_+_140235469 0.36 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr11_+_60048129 0.36 ENST00000355131.3
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr9_-_13165457 0.36 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr14_+_22446680 0.36 ENST00000390443.3
TRAV8-6
T cell receptor alpha variable 8-6
chr3_-_191000172 0.35 ENST00000427544.2
UTS2B
urotensin 2B
chr3_+_148545586 0.35 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr7_-_22234381 0.35 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr9_+_70856397 0.34 ENST00000360171.6
CBWD3
COBW domain containing 3
chr9_+_108424738 0.34 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr10_-_47151341 0.34 ENST00000422732.2
LINC00842
long intergenic non-protein coding RNA 842
chr4_+_174089904 0.33 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr19_-_10697895 0.33 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr10_+_135207623 0.31 ENST00000317502.6
ENST00000432508.3
MTG1
mitochondrial ribosome-associated GTPase 1
chr5_-_24645078 0.29 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr12_+_59989918 0.29 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr17_+_48823975 0.29 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr17_-_26220366 0.27 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr2_+_86947296 0.25 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr9_-_139372141 0.25 ENST00000313050.7
SEC16A
SEC16 homolog A (S. cerevisiae)
chr20_+_34824355 0.24 ENST00000397286.3
ENST00000320849.4
ENST00000373932.3
AAR2
AAR2 splicing factor homolog (S. cerevisiae)
chr3_-_119182523 0.24 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chrX_+_108779004 0.23 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr17_-_38821373 0.23 ENST00000394052.3
KRT222
keratin 222
chr7_-_92777606 0.22 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr1_+_160370344 0.22 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr19_+_42300548 0.22 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr9_+_70856899 0.22 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chrX_-_19689106 0.22 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr12_+_94071341 0.21 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr17_+_45000483 0.21 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
GOSR2
golgi SNAP receptor complex member 2
chr8_-_27168737 0.21 ENST00000521253.1
ENST00000305364.4
TRIM35
tripartite motif containing 35
chr9_-_70490107 0.20 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr13_+_96085847 0.20 ENST00000376873.3
CLDN10
claudin 10
chr2_+_128377550 0.19 ENST00000437387.1
ENST00000409090.1
MYO7B
myosin VIIB
chr15_-_43785303 0.19 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr4_-_95264008 0.19 ENST00000295256.5
HPGDS
hematopoietic prostaglandin D synthase
chr2_-_158345462 0.17 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chrX_+_102883620 0.17 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr11_+_60048053 0.17 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr2_-_178128250 0.17 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr8_+_119294456 0.17 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr3_-_48956818 0.17 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr20_+_30458431 0.17 ENST00000375938.4
ENST00000535842.1
ENST00000310998.4
ENST00000375921.2
TTLL9
tubulin tyrosine ligase-like family, member 9
chr2_-_178128528 0.16 ENST00000397063.4
ENST00000421929.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr1_+_145883868 0.15 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr10_-_28571015 0.15 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr4_+_166300084 0.15 ENST00000402744.4
CPE
carboxypeptidase E
chr12_-_8043736 0.15 ENST00000539924.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr12_-_53893399 0.15 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr19_+_9361606 0.14 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr5_+_175511859 0.14 ENST00000503724.2
ENST00000253490.4
FAM153B
family with sequence similarity 153, member B
chr2_+_109237717 0.14 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_154360616 0.14 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
OPRM1
opioid receptor, mu 1
chr18_-_74839891 0.13 ENST00000581878.1
MBP
myelin basic protein
chrX_+_103031421 0.13 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr2_-_136288113 0.12 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr11_+_59480899 0.12 ENST00000300150.7
STX3
syntaxin 3
chr1_-_160492994 0.11 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr7_+_142498725 0.11 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr13_-_37633567 0.11 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr12_+_48516357 0.11 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
PFKM
phosphofructokinase, muscle
chr11_+_6226782 0.11 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr1_+_144989309 0.10 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr2_-_225266711 0.10 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr19_+_47852538 0.10 ENST00000328771.4
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr12_-_15038779 0.10 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr2_-_225266743 0.10 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr3_+_42977846 0.10 ENST00000383748.4
KRBOX1
KRAB box domain containing 1
chr11_-_40315640 0.10 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr5_-_150473127 0.10 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr22_-_50219548 0.10 ENST00000404034.1
BRD1
bromodomain containing 1
chr14_+_23067146 0.09 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr11_-_84634447 0.09 ENST00000532653.1
DLG2
discs, large homolog 2 (Drosophila)
chr13_+_24883703 0.09 ENST00000332018.4
C1QTNF9
C1q and tumor necrosis factor related protein 9
chr3_+_187871060 0.09 ENST00000448637.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_173116225 0.08 ENST00000457714.1
NLGN1
neuroligin 1
chr11_-_72504681 0.08 ENST00000538536.1
ENST00000543304.1
ENST00000540587.1
ENST00000334805.6
STARD10
StAR-related lipid transfer (START) domain containing 10
chr15_-_34880646 0.08 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chr12_-_54982300 0.08 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr7_-_7575477 0.07 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr1_-_146040968 0.07 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr1_+_202789394 0.07 ENST00000330493.5
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr15_-_35047166 0.07 ENST00000290374.4
GJD2
gap junction protein, delta 2, 36kDa
chr5_+_140480083 0.07 ENST00000231130.2
PCDHB3
protocadherin beta 3
chr4_-_163085107 0.06 ENST00000379164.4
FSTL5
follistatin-like 5
chr3_-_149470229 0.06 ENST00000473414.1
COMMD2
COMM domain containing 2
chr2_+_200775971 0.06 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69
chr16_-_2314222 0.06 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr11_-_84634217 0.06 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chrX_+_73164167 0.05 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr20_+_56964169 0.05 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr17_-_76719807 0.05 ENST00000589297.1
CYTH1
cytohesin 1
chr16_-_11922665 0.05 ENST00000573319.1
ENST00000577041.1
ENST00000574028.1
ENST00000571259.1
ENST00000573037.1
ENST00000571158.1
BCAR4
breast cancer anti-estrogen resistance 4 (non-protein coding)
chr21_-_33984456 0.04 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
AP000275.65
C21orf59
Uncharacterized protein
chromosome 21 open reading frame 59
chr2_+_108145913 0.04 ENST00000443205.1
AC096669.3
AC096669.3
chr8_-_82395461 0.04 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr9_-_5833027 0.04 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr19_-_40228657 0.04 ENST00000221804.4
CLC
Charcot-Leyden crystal galectin
chr3_-_151176497 0.04 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr19_+_12175504 0.03 ENST00000439326.3
ZNF844
zinc finger protein 844
chr7_+_55980331 0.03 ENST00000429591.2
ZNF713
zinc finger protein 713
chr3_-_187455680 0.03 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr9_-_21974820 0.03 ENST00000579122.1
ENST00000498124.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_+_95616933 0.02 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr8_-_87242589 0.02 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr11_-_117800080 0.02 ENST00000524993.1
ENST00000528626.1
ENST00000445164.2
ENST00000430170.2
ENST00000526090.1
TMPRSS13
transmembrane protease, serine 13
chr15_+_78832747 0.02 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr14_-_101295407 0.02 ENST00000596284.1
AL117190.2
AL117190.2
chrX_-_23926004 0.01 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr8_-_25902876 0.01 ENST00000520164.1
EBF2
early B-cell factor 2
chrX_-_131262048 0.01 ENST00000298542.4
FRMD7
FERM domain containing 7
chr11_-_118122996 0.00 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr18_+_71815743 0.00 ENST00000169551.6
ENST00000580087.1
TIMM21
translocase of inner mitochondrial membrane 21 homolog (yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.9 2.8 GO:0061461 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.4 0.4 GO:0008217 regulation of blood pressure(GO:0008217)
0.3 0.8 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.3 1.9 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.7 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.8 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 4.0 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.4 GO:0034059 response to anoxia(GO:0034059)
0.1 0.4 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 1.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.2 GO:0061341 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.3 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.8 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 3.9 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 1.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.7 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 4.8 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334) positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.6 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.6 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0005879 axonemal microtubule(GO:0005879)
0.4 1.8 GO:0097224 sperm connecting piece(GO:0097224)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 6.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.3 4.0 GO:0031862 prostanoid receptor binding(GO:0031862)
0.7 2.8 GO:0005287 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.3 0.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 1.0 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 2.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 5.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149) D-glucose transmembrane transporter activity(GO:0055056)
0.0 4.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 2.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 4.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway