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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for LMX1B_MNX1_RAX2

Z-value: 0.68

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Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
LMX1B
ENSG00000136944.13 LIM homeobox transcription factor 1 beta
MNX1
ENSG00000130675.10 motor neuron and pancreas homeobox 1
RAX2
ENSG00000173976.11 retina and anterior neural fold homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MNX1hg19_v2_chr7_-_156803329_156803362-0.412.3e-02Click!
LMX1Bhg19_v2_chr9_+_129376722_129376748-0.029.3e-01Click!
RAX2hg19_v2_chr19_-_3772209_37722360.009.8e-01Click!

Activity profile of LMX1B_MNX1_RAX2 motif

Sorted Z-values of LMX1B_MNX1_RAX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_152386732 5.73 ENST00000271835.3
CRNN
cornulin
chr4_+_69313145 3.39 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr4_+_169013666 2.61 ENST00000359299.3
ANXA10
annexin A10
chr12_-_28122980 2.10 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr2_+_158114051 2.08 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr7_+_134464376 2.08 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr11_+_33061543 1.94 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr7_+_134464414 1.84 ENST00000361901.2
CALD1
caldesmon 1
chr5_+_31193847 1.83 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr12_+_26348582 1.80 ENST00000535504.1
SSPN
sarcospan
chr17_-_38859996 1.74 ENST00000264651.2
KRT24
keratin 24
chr12_-_28123206 1.69 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr1_-_152131703 1.57 ENST00000316073.3
RPTN
repetin
chr4_+_169418255 1.44 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr1_+_154401791 1.40 ENST00000476006.1
IL6R
interleukin 6 receptor
chr4_-_57547454 1.39 ENST00000556376.2
HOPX
HOP homeobox
chr4_-_57547870 1.37 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr6_+_130339710 1.30 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr7_-_107642348 1.25 ENST00000393561.1
LAMB1
laminin, beta 1
chr7_+_77428066 1.24 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr12_-_89746173 1.24 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr6_+_151646800 1.22 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr15_+_93443419 1.21 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr12_+_4385230 1.16 ENST00000536537.1
CCND2
cyclin D2
chr11_-_121986923 1.13 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr4_-_39979576 1.09 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr7_-_28220354 1.08 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr17_-_64225508 1.06 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_-_32157947 1.02 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr7_+_77428149 1.02 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr4_-_20985632 0.94 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr3_-_33686925 0.94 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr2_-_208031943 0.92 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_107712173 0.86 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr17_-_39150385 0.86 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr18_+_34124507 0.84 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr9_+_12693336 0.82 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chrX_-_153602991 0.77 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr12_-_10978957 0.73 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr12_-_95510743 0.71 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr7_-_107443652 0.71 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr1_-_24469602 0.71 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr1_+_62439037 0.71 ENST00000545929.1
INADL
InaD-like (Drosophila)
chrX_-_153599578 0.69 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr19_-_51523412 0.68 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr12_+_26348246 0.67 ENST00000422622.2
SSPN
sarcospan
chr18_+_29027696 0.67 ENST00000257189.4
DSG3
desmoglein 3
chr18_+_21572737 0.67 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr19_-_51522955 0.65 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr12_-_52967600 0.65 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr18_-_44181442 0.64 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr4_-_139163491 0.63 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_+_190541153 0.63 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr4_-_143227088 0.63 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr2_-_100987007 0.63 ENST00000595083.1
AC012493.2
Uncharacterized protein
chr14_-_57272366 0.62 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr7_-_23510086 0.61 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr10_+_98741041 0.60 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr4_-_69111401 0.60 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr19_-_51523275 0.59 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr3_+_130569429 0.57 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr12_+_28410128 0.57 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chrX_-_106243451 0.56 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr1_+_115572415 0.56 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr3_+_121774202 0.55 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr3_-_141747950 0.54 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_237167718 0.54 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr3_-_74570291 0.53 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr17_-_9694614 0.53 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr3_-_52090461 0.50 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr1_+_50569575 0.47 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr12_-_52585765 0.46 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr1_+_107683436 0.46 ENST00000370068.1
NTNG1
netrin G1
chr12_+_26348429 0.45 ENST00000242729.2
SSPN
sarcospan
chr6_-_31107127 0.44 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr1_-_185597619 0.44 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr7_-_87342564 0.43 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr3_-_108248169 0.42 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr3_-_113897899 0.42 ENST00000383673.2
ENST00000295881.7
DRD3
dopamine receptor D3
chr17_+_47448102 0.41 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr2_+_68961934 0.41 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr12_-_118797475 0.41 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr3_+_111718173 0.40 ENST00000494932.1
TAGLN3
transgelin 3
chr8_+_107460147 0.39 ENST00000442977.2
OXR1
oxidation resistance 1
chr2_+_68961905 0.39 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr1_-_204135450 0.39 ENST00000272190.8
ENST00000367195.2
REN
renin
chr14_-_51027838 0.39 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chrX_+_99839799 0.38 ENST00000373031.4
TNMD
tenomodulin
chr21_-_31859755 0.38 ENST00000334055.3
KRTAP19-2
keratin associated protein 19-2
chr12_-_3862245 0.37 ENST00000252322.1
ENST00000440314.2
EFCAB4B
EF-hand calcium binding domain 4B
chr19_+_1440838 0.37 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr4_+_40198527 0.37 ENST00000381799.5
RHOH
ras homolog family member H
chr5_+_126984710 0.36 ENST00000379445.3
CTXN3
cortexin 3
chr5_-_147286065 0.36 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr17_+_41363854 0.36 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr8_+_22424551 0.35 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr20_-_50722183 0.35 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr2_+_105050794 0.35 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chrX_-_21676442 0.34 ENST00000379499.2
KLHL34
kelch-like family member 34
chr13_-_99667960 0.34 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr7_+_100136811 0.33 ENST00000300176.4
ENST00000262935.4
AGFG2
ArfGAP with FG repeats 2
chr9_+_136501478 0.33 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr19_+_10397648 0.32 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr4_+_3388057 0.32 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr1_-_234667504 0.32 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr2_+_223162866 0.32 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr7_-_83278322 0.32 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr14_+_32798547 0.31 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr20_-_25320367 0.31 ENST00000450393.1
ENST00000491682.1
ABHD12
abhydrolase domain containing 12
chr19_-_14064114 0.31 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1
podocan-like 1
chr4_+_169418195 0.31 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr3_-_33686743 0.31 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr2_+_90248739 0.30 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr12_+_93096619 0.30 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chrX_+_107288239 0.30 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr2_-_214016314 0.30 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr14_+_73706308 0.30 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr16_+_57279004 0.30 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr8_+_55528627 0.29 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr2_-_207024134 0.29 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_242612779 0.29 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr12_-_54653313 0.28 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr17_+_39261584 0.28 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr15_+_75080883 0.28 ENST00000567571.1
CSK
c-src tyrosine kinase
chr12_-_10955226 0.27 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr4_-_143226979 0.27 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr14_+_32798462 0.27 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr9_-_131486367 0.27 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr21_-_31864275 0.27 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr17_-_39211463 0.27 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr21_-_22175450 0.26 ENST00000435279.2
LINC00320
long intergenic non-protein coding RNA 320
chr2_-_136678123 0.26 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr1_+_68150744 0.26 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr13_-_36050819 0.26 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr15_-_55562479 0.26 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr21_-_42219065 0.25 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr5_-_126409159 0.25 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr3_+_111718036 0.25 ENST00000455401.2
TAGLN3
transgelin 3
chr4_-_116034979 0.25 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr1_+_107683644 0.25 ENST00000370067.1
NTNG1
netrin G1
chr3_-_113897545 0.25 ENST00000467632.1
DRD3
dopamine receptor D3
chr17_-_40337470 0.25 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr17_-_39254391 0.25 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chrY_-_13524717 0.24 ENST00000331172.6
SLC9B1P1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr3_+_158787041 0.24 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr9_-_95166841 0.24 ENST00000262551.4
OGN
osteoglycin
chr5_+_66300446 0.24 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr20_+_30697298 0.23 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr17_+_59489112 0.23 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr11_+_63606373 0.23 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr17_-_39222131 0.23 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr15_-_55563072 0.22 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr3_+_111717511 0.22 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr9_-_95166884 0.22 ENST00000375561.5
OGN
osteoglycin
chr3_-_151034734 0.22 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr1_+_107682629 0.22 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr14_-_60097297 0.22 ENST00000395090.1
RTN1
reticulon 1
chr3_+_16306837 0.22 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr3_+_111717600 0.22 ENST00000273368.4
TAGLN3
transgelin 3
chrX_-_18690210 0.22 ENST00000379984.3
RS1
retinoschisin 1
chr12_-_112123524 0.21 ENST00000327551.6
BRAP
BRCA1 associated protein
chr2_+_171034646 0.21 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr12_-_22063787 0.21 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_-_89951028 0.20 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr3_-_167191814 0.20 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr1_+_225600404 0.20 ENST00000366845.2
AC092811.1
AC092811.1
chr14_-_60097524 0.20 ENST00000342503.4
RTN1
reticulon 1
chr14_-_72458326 0.20 ENST00000542853.1
AC005477.1
AC005477.1
chr12_+_122688090 0.20 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr17_+_79495397 0.20 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chrX_-_19988382 0.19 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23
chromosome X open reading frame 23
chr8_-_93107696 0.19 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_38938786 0.19 ENST00000301656.3
KRT27
keratin 27
chr4_+_88529681 0.19 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr2_-_99871570 0.19 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr1_+_155023757 0.18 ENST00000356955.2
ENST00000449910.2
ENST00000359280.4
ENST00000360674.4
ENST00000368412.3
ENST00000355956.2
ENST00000368410.2
ENST00000271836.6
ENST00000368413.1
ENST00000531455.1
ENST00000447332.3
ADAM15
ADAM metallopeptidase domain 15
chr4_-_76944621 0.18 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr9_+_82187487 0.18 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr5_+_140855495 0.18 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr9_+_82187630 0.17 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_+_168250194 0.17 ENST00000367821.3
TBX19
T-box 19
chr12_+_93096759 0.17 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr12_-_14849470 0.17 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr2_-_50574856 0.17 ENST00000342183.5
NRXN1
neurexin 1
chr8_+_26150628 0.17 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr2_+_45168875 0.16 ENST00000260653.3
SIX3
SIX homeobox 3
chrM_-_14670 0.16 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr7_+_50348268 0.16 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr2_-_190927447 0.16 ENST00000260950.4
MSTN
myostatin
chr10_-_24770632 0.16 ENST00000596413.1
AL353583.1
AL353583.1
chr17_-_39191107 0.16 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr3_-_178984759 0.15 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr6_+_30029008 0.15 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1
zinc ribbon domain containing 1
chr7_-_14029515 0.15 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr7_-_14029283 0.15 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr19_+_48949030 0.15 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr17_+_39382900 0.15 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr2_-_207023918 0.15 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_242162375 0.14 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr12_-_53171128 0.14 ENST00000332411.2
KRT76
keratin 76

Network of associatons between targets according to the STRING database.

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0002384 hepatic immune response(GO:0002384)
0.4 1.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.4 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 1.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.5 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.2 0.6 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.7 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 3.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 1.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 1.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.6 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 1.7 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.0 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 0.7 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.4 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.8 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 1.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 6.9 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 1.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 2.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0061738 late endosomal microautophagy(GO:0061738)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0033189 response to vitamin A(GO:0033189)
0.0 5.3 GO:0009408 response to heat(GO:0009408)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0051795 catagen(GO:0042637) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0023058 adaptation of signaling pathway(GO:0023058)
0.0 0.1 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.0 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 1.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 1.2 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.0 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 6.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0031523 Myb complex(GO:0031523)
0.4 1.2 GO:0005607 laminin-2 complex(GO:0005607)
0.4 1.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 3.9 GO:0030478 actin cap(GO:0030478)
0.2 1.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 2.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 2.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.8 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.4 1.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.9 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 3.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 3.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 1.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.4 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 2.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 1.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 1.3 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.4 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 7.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 4.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions