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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MAFA

Z-value: 0.77

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Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
MAFA
ENSG00000182759.3 MAF bZIP transcription factor A

Activity profile of MAFA motif

Sorted Z-values of MAFA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_39270725 2.11 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr22_-_28197486 1.96 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr11_+_118826999 1.72 ENST00000264031.2
UPK2
uroplakin 2
chr2_+_33172221 1.71 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr10_+_120967072 1.68 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr2_+_85811525 1.56 ENST00000306384.4
VAMP5
vesicle-associated membrane protein 5
chr11_+_72929319 1.52 ENST00000393597.2
ENST00000311131.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr11_+_72929402 1.47 ENST00000393596.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr20_+_306177 1.44 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr15_+_90744533 1.43 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr16_+_56598961 1.39 ENST00000219162.3
MT4
metallothionein 4
chrX_-_106959631 1.33 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr19_-_51141196 1.26 ENST00000338916.4
SYT3
synaptotagmin III
chr6_+_7727030 1.14 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr11_-_66103932 1.11 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr19_-_43099070 1.10 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr17_-_39324424 1.08 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr19_-_4124079 1.03 ENST00000394867.4
ENST00000262948.5
MAP2K2
mitogen-activated protein kinase kinase 2
chr11_-_66103867 1.02 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr10_-_79397391 1.01 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr20_+_306221 0.98 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr16_-_46865286 0.98 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr2_+_118846008 0.96 ENST00000245787.4
INSIG2
insulin induced gene 2
chr17_-_41623009 0.91 ENST00000393664.2
ETV4
ets variant 4
chr10_+_124221036 0.89 ENST00000368984.3
HTRA1
HtrA serine peptidase 1
chr10_-_29811456 0.88 ENST00000535393.1
SVIL
supervillin
chrX_-_43741594 0.87 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr15_+_80696666 0.87 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_-_73133959 0.83 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A
syntaxin 1A (brain)
chr10_-_75676400 0.78 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr7_-_100860851 0.77 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr1_+_110754094 0.75 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr5_+_139739772 0.73 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr2_+_191745560 0.73 ENST00000338435.4
GLS
glutaminase
chr17_-_47925379 0.71 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr2_+_115199876 0.67 ENST00000436732.1
ENST00000410059.1
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr3_+_185304059 0.66 ENST00000427465.2
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr2_-_30143525 0.65 ENST00000431873.1
ALK
anaplastic lymphoma receptor tyrosine kinase
chr6_+_42896865 0.62 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr5_-_114505624 0.61 ENST00000513154.1
TRIM36
tripartite motif containing 36
chr18_+_77623668 0.61 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr5_-_22853429 0.61 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr12_-_105478339 0.60 ENST00000424857.2
ENST00000258494.9
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr17_-_39254391 0.59 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr5_+_60933634 0.59 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr16_-_46865047 0.58 ENST00000394806.2
C16orf87
chromosome 16 open reading frame 87
chr9_-_100000957 0.55 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
RP11-498P14.5
chr11_-_104817919 0.55 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chrX_+_68725084 0.55 ENST00000252338.4
FAM155B
family with sequence similarity 155, member B
chr9_-_28670283 0.54 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr8_+_85095769 0.54 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr19_+_18451391 0.54 ENST00000269919.6
ENST00000604499.2
ENST00000595066.1
ENST00000252813.5
PGPEP1
pyroglutamyl-peptidase I
chr8_+_85095497 0.53 ENST00000522455.1
ENST00000521695.1
RALYL
RALY RNA binding protein-like
chr11_+_107462471 0.52 ENST00000600612.1
AP000889.3
HCG2032453; Uncharacterized protein; cDNA FLJ25337 fis, clone TST00714
chr1_-_38325256 0.52 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr2_+_191745535 0.50 ENST00000320717.3
GLS
glutaminase
chr12_-_21654479 0.49 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RECQL
RecQ protein-like (DNA helicase Q1-like)
chr1_+_200842083 0.47 ENST00000304244.2
GPR25
G protein-coupled receptor 25
chrX_-_63425561 0.46 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr17_-_76128488 0.46 ENST00000322914.3
TMC6
transmembrane channel-like 6
chr19_-_2050852 0.45 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr10_-_79397479 0.44 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_+_21654714 0.43 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr10_+_135122906 0.42 ENST00000368554.4
ZNF511
zinc finger protein 511
chr14_+_24600484 0.42 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr17_+_38465441 0.42 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr4_+_74606223 0.41 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr13_+_28194873 0.41 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr6_+_116692102 0.40 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr19_+_18451439 0.40 ENST00000597431.2
PGPEP1
pyroglutamyl-peptidase I
chr6_-_99797522 0.40 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr3_-_48754599 0.39 ENST00000413654.1
ENST00000454335.1
ENST00000440424.1
ENST00000449610.1
ENST00000443964.1
ENST00000417896.1
ENST00000413298.1
ENST00000449563.1
ENST00000443853.1
ENST00000437427.1
ENST00000446860.1
ENST00000412850.1
ENST00000424035.1
ENST00000340879.4
ENST00000431721.2
ENST00000434860.1
ENST00000328631.5
ENST00000432678.2
IP6K2
inositol hexakisphosphate kinase 2
chr3_+_42190714 0.39 ENST00000449246.1
TRAK1
trafficking protein, kinesin binding 1
chr21_+_41239243 0.38 ENST00000328619.5
PCP4
Purkinje cell protein 4
chr9_+_2621798 0.37 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr9_+_33629119 0.37 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr22_+_23063100 0.37 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr9_+_2622085 0.36 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr20_-_23066953 0.36 ENST00000246006.4
CD93
CD93 molecule
chr7_-_108168580 0.35 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr10_-_49701686 0.35 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr3_-_126277796 0.34 ENST00000318225.2
C3orf22
chromosome 3 open reading frame 22
chr10_-_70231639 0.33 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2
DNA replication helicase/nuclease 2
chr7_-_151433342 0.32 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr11_-_777467 0.32 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
PDDC1
Parkinson disease 7 domain containing 1
chr17_+_31318886 0.32 ENST00000269053.3
ENST00000394638.1
SPACA3
sperm acrosome associated 3
chr17_+_41363854 0.31 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr14_+_81421861 0.31 ENST00000298171.2
TSHR
thyroid stimulating hormone receptor
chr12_-_2027639 0.31 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr5_+_176853702 0.30 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr22_+_23161491 0.30 ENST00000390316.2
IGLV3-9
immunoglobulin lambda variable 3-9 (gene/pseudogene)
chr12_+_56546363 0.29 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr14_+_81421355 0.29 ENST00000541158.2
TSHR
thyroid stimulating hormone receptor
chr10_+_102505468 0.29 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chrX_-_92928557 0.29 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr22_+_22599075 0.29 ENST00000403807.3
VPREB1
pre-B lymphocyte 1
chr17_-_10325261 0.28 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr4_-_10118348 0.27 ENST00000502702.1
WDR1
WD repeat domain 1
chr8_-_63998590 0.26 ENST00000260116.4
TTPA
tocopherol (alpha) transfer protein
chr16_-_79015739 0.25 ENST00000594986.1
PIH1
HCG1979943; Uncharacterized protein
chr17_+_7323634 0.25 ENST00000323675.3
SPEM1
spermatid maturation 1
chr15_-_23086394 0.24 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr8_-_89339705 0.24 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr22_+_22697537 0.23 ENST00000427632.2
IGLV9-49
immunoglobulin lambda variable 9-49
chr19_-_48547294 0.22 ENST00000293255.2
CABP5
calcium binding protein 5
chr11_+_33563821 0.21 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr10_-_81708854 0.21 ENST00000372292.3
SFTPD
surfactant protein D
chr17_-_39728303 0.19 ENST00000588431.1
ENST00000246662.4
KRT9
keratin 9
chr15_-_90456114 0.18 ENST00000398333.3
C15orf38-AP3S2
C15orf38-AP3S2 readthrough
chr3_+_196439275 0.18 ENST00000296333.5
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr12_+_79258547 0.18 ENST00000457153.2
SYT1
synaptotagmin I
chr1_+_66458072 0.18 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr17_+_25936862 0.18 ENST00000582410.1
KSR1
kinase suppressor of ras 1
chr2_+_103236004 0.17 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr11_+_107461948 0.17 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chr11_-_70507901 0.17 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr12_+_79258444 0.17 ENST00000261205.4
SYT1
synaptotagmin I
chr16_+_56225248 0.15 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr20_-_31592113 0.15 ENST00000420875.1
ENST00000375519.2
ENST00000375523.3
ENST00000356173.3
SUN5
Sad1 and UNC84 domain containing 5
chr15_-_90456156 0.13 ENST00000357484.5
C15orf38
chromosome 15 open reading frame 38
chr11_-_57177586 0.13 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr7_-_135412925 0.13 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr22_+_22730353 0.12 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr20_-_30795511 0.12 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chrX_-_1511617 0.12 ENST00000381401.5
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr7_+_100860949 0.12 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr6_-_24489842 0.12 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr3_+_141121164 0.11 ENST00000510338.1
ENST00000504673.1
ZBTB38
zinc finger and BTB domain containing 38
chr22_+_22599189 0.11 ENST00000302273.2
VPREB1
pre-B lymphocyte 1
chr19_+_36103631 0.11 ENST00000203166.5
ENST00000379045.2
HAUS5
HAUS augmin-like complex, subunit 5
chr11_-_2182388 0.10 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr19_+_33182823 0.10 ENST00000397061.3
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr6_+_22221010 0.10 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr1_-_32403370 0.10 ENST00000534796.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr4_+_2470664 0.09 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4
ring finger protein 4
chr11_+_111411384 0.08 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
LAYN
layilin
chr22_+_48972118 0.08 ENST00000358295.5
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr6_+_97372596 0.08 ENST00000369261.4
KLHL32
kelch-like family member 32
chr13_-_103426081 0.07 ENST00000376022.1
ENST00000376021.4
TEX30
testis expressed 30
chr19_-_50464338 0.07 ENST00000426971.2
ENST00000447370.2
SIGLEC11
sialic acid binding Ig-like lectin 11
chr4_-_151936865 0.06 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr13_-_103426112 0.05 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr17_+_18759612 0.05 ENST00000432893.2
ENST00000414602.1
ENST00000574522.1
ENST00000570450.1
ENST00000419071.2
PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr11_-_64660916 0.04 ENST00000413053.1
MIR194-2
microRNA 194-2
chr11_-_62783276 0.03 ENST00000535878.1
ENST00000545207.1
SLC22A8
solute carrier family 22 (organic anion transporter), member 8
chr22_-_30662828 0.03 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr19_+_12949251 0.02 ENST00000251472.4
MAST1
microtubule associated serine/threonine kinase 1
chr3_-_49823941 0.02 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
IP6K1
inositol hexakisphosphate kinase 1
chr15_-_41047421 0.02 ENST00000560460.1
ENST00000338376.3
ENST00000560905.1
RMDN3
regulator of microtubule dynamics 3
chr17_-_3796334 0.02 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr3_+_196439170 0.01 ENST00000392391.3
ENST00000314118.4
PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr3_+_107241882 0.01 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chr6_-_74161977 0.01 ENST00000370318.1
ENST00000370315.3
MB21D1
Mab-21 domain containing 1
chr15_-_23086259 0.01 ENST00000538684.1
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097187 dentinogenesis(GO:0097187)
0.3 0.8 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 0.3 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.2 1.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 2.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 2.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 3.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 1.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.2 0.8 GO:0010807 positive regulation of norepinephrine secretion(GO:0010701) regulation of synaptic vesicle priming(GO:0010807)
0.2 0.6 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.2 1.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.2 1.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.6 GO:0036269 swimming behavior(GO:0036269)
0.1 1.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.5 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.9 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.7 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.8 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 1.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.3 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.7 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0 0.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 1.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 1.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 2.4 GO:0021510 spinal cord development(GO:0021510)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.7 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.4 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.8 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 1.7 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 2.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.3 1.7 GO:0050436 microfibril binding(GO:0050436)
0.3 0.8 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 1.2 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 0.5 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 1.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.3 GO:0043426 MRF binding(GO:0043426)
0.1 3.0 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 2.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.9 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.8 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation