Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
Navigation
Downloads
Results for MAFF_MAFG
Z-value: 1.35
Motif logo
Transcription factors associated with MAFF_MAFG
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MAFF | hg19_v2_chr22_+_38609538_38609547 | -0.57 | 9.0e-04 | Click! |
| MAFG | hg19_v2_chr17_-_79885576_79885624 | -0.43 | 1.9e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MAFF_MAFG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 28.6 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 13.4 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 1.9 | 13.3 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.2 | 8.4 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 7.6 | GO:0022900 | electron transport chain(GO:0022900) |
| 0.4 | 7.4 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.1 | 6.1 | GO:0032729 | positive regulation of interferon-gamma production(GO:0032729) |
| 1.4 | 5.6 | GO:2000768 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.0 | 5.4 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.0 | 5.4 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 29.2 | GO:0005844 | polysome(GO:0005844) |
| 0.7 | 13.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 11.1 | GO:0030286 | dynein complex(GO:0030286) |
| 0.6 | 6.6 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 6.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.3 | 5.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 4.5 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 1.1 | 4.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 3.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.5 | 3.3 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 29.7 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.5 | 10.0 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.9 | 7.5 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.2 | 6.6 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.2 | 6.6 | GO:0038187 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 6.0 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 1.5 | 5.9 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.4 | 5.3 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 1.7 | 5.2 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 0.9 | 5.2 | GO:0047685 | amine sulfotransferase activity(GO:0047685) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.0 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 5.5 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.3 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 1.4 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.0 | 1.0 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.9 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.5 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 0.1 | PID TRAIL PATHWAY | TRAIL signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 29.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.2 | 6.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.3 | 6.1 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.1 | 5.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 3.9 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 3.7 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 2.3 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 1.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 1.7 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 1.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |