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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MAFF_MAFG

Z-value: 1.35

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Transcription factors associated with MAFF_MAFG

Gene Symbol Gene ID Gene Info
ENSG00000185022.7 MAF bZIP transcription factor F
ENSG00000197063.6 MAF bZIP transcription factor G

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFFhg19_v2_chr22_+_38609538_38609547-0.579.0e-04Click!
MAFGhg19_v2_chr17_-_79885576_79885624-0.431.9e-02Click!

Activity profile of MAFF_MAFG motif

Sorted Z-values of MAFF_MAFG motif

Promoter Log-likelihood Transcript Gene Gene Info
chrY_+_2709527 21.53 ENST00000250784.8
ribosomal protein S4, Y-linked 1
chr1_+_85527987 9.96 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WD repeat domain 63
chr19_+_5914213 9.36 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
calcyphosine
chr12_+_111051902 8.47 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
tectonic family member 1
chrY_+_2709906 7.98 ENST00000430575.1
ribosomal protein S4, Y-linked 1
chr5_-_54468974 7.51 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
cell division cycle 20B
chr6_+_33043703 6.07 ENST00000418931.2
ENST00000535465.1
major histocompatibility complex, class II, DP beta 1
chr17_-_61512545 5.86 ENST00000585153.1
cytochrome b561
chr4_-_16077741 5.63 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
prominin 1
chr6_-_43478239 5.32 ENST00000372441.1
leucine rich repeat containing 73
chr16_+_30211181 5.17 ENST00000395138.2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_80574854 5.11 ENST00000305904.6
ENST00000568035.1
dynein, light chain, roadblock-type 2
chr4_+_15480828 4.86 ENST00000389652.5
coiled-coil and C2 domain containing 2A
chr1_-_109655355 4.50 ENST00000369945.3
chromosome 1 open reading frame 194
chr11_-_5248294 4.41 ENST00000335295.4
hemoglobin, beta
chr5_+_140019079 4.40 ENST00000252100.6
transmembrane and coiled-coil domains 6
chr1_-_109655377 4.31 ENST00000369948.3
chromosome 1 open reading frame 194
chr16_+_4838412 4.27 ENST00000589327.1
small integral membrane protein 22
chr2_+_120189422 4.10 ENST00000306406.4
transmembrane protein 37
chr7_-_154863264 4.01 ENST00000395731.2
ENST00000543018.1
HTR5A antisense RNA 1
chr10_+_134150835 3.85 ENST00000432555.2
leucine rich repeat containing 27
chr17_+_260097 3.65 ENST00000360127.6
ENST00000571106.1
ENST00000491373.1
chromosome 17 open reading frame 97
chr9_-_138391692 3.65 ENST00000429260.2
chromosome 9 open reading frame 116
chr12_-_71533055 3.64 ENST00000552128.1
tetraspanin 8
chr1_+_17248418 3.49 ENST00000375541.5
ciliary rootlet coiled-coil, rootletin
chr15_+_90895471 3.43 ENST00000354377.3
ENST00000379090.5
zinc finger protein 774
chr2_-_220108309 3.40 ENST00000409640.1
galactosidase, beta 1-like
chr12_-_10282836 3.36 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr11_+_27076764 3.24 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_+_108308513 3.18 ENST00000361582.3
DAZ interacting zinc finger protein 3
chr8_-_110620284 3.09 ENST00000529690.1
syntabulin (syntaxin-interacting)
chr17_-_4689649 3.01 ENST00000441199.2
ENST00000416307.2
vitelline membrane outer layer 1 homolog (chicken)
chrX_-_55187531 2.92 ENST00000489298.1
ENST00000477847.2
family with sequence similarity 104, member B
chr17_-_4689727 2.84 ENST00000328739.5
ENST00000354194.4
vitelline membrane outer layer 1 homolog (chicken)
chrX_-_55187588 2.81 ENST00000472571.2
ENST00000332132.4
ENST00000425133.2
ENST00000358460.4
family with sequence similarity 104, member B
chr5_+_140602904 2.58 ENST00000515856.2
ENST00000239449.4
protocadherin beta 14
chr10_+_115803650 2.54 ENST00000369295.2
adrenoceptor beta 1
chr16_+_82068830 2.42 ENST00000199936.4
hydroxysteroid (17-beta) dehydrogenase 2
chr5_-_75013193 2.29 ENST00000514838.2
ENST00000506164.1
ENST00000502826.1
ENST00000503835.1
ENST00000428202.2
ENST00000380475.2
POC5 centriolar protein
chr1_+_183774240 2.23 ENST00000360851.3
ral guanine nucleotide dissociation stimulator-like 1
chr16_+_4838393 2.22 ENST00000589721.1
small integral membrane protein 22
chr12_-_10282742 2.08 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr5_-_169626104 2.04 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
chr12_-_10282681 2.03 ENST00000533022.1
C-type lectin domain family 7, member A
chr1_-_150669500 1.95 ENST00000271732.3
golgi phosphoprotein 3-like
chr5_+_140019004 1.91 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
transmembrane and coiled-coil domains 6
chr7_-_150777874 1.91 ENST00000540185.1
Fas-activated serine/threonine kinase
chr1_-_207095324 1.88 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr11_+_75428857 1.87 ENST00000198801.5
monoacylglycerol O-acyltransferase 2
chr7_-_86849883 1.86 ENST00000433078.1
transmembrane protein 243, mitochondrial
chr17_+_53343577 1.85 ENST00000573945.1
hepatic leukemia factor
chr3_-_46506358 1.84 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr12_-_39837192 1.79 ENST00000361961.3
ENST00000395670.3
kinesin family member 21A
chr12_-_39836772 1.78 ENST00000541463.2
ENST00000361418.5
ENST00000544797.2
kinesin family member 21A
chr22_-_30867973 1.75 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14-like 3 (S. cerevisiae)
chr7_-_122526799 1.74 ENST00000334010.7
ENST00000313070.7
Ca++-dependent secretion activator 2
chr11_-_34938039 1.73 ENST00000395787.3
APAF1 interacting protein
chr10_-_116444371 1.70 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr7_-_150777920 1.68 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chr22_-_37172111 1.67 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
intraflagellar transport 27 homolog (Chlamydomonas)
chr6_+_27215494 1.66 ENST00000230582.3
protease, serine, 16 (thymus)
chr19_-_33555780 1.66 ENST00000254260.3
ENST00000400226.4
rhophilin, Rho GTPase binding protein 2
chr7_-_150777949 1.64 ENST00000482571.1
Fas-activated serine/threonine kinase
chr19_+_44645700 1.64 ENST00000592437.1
zinc finger protein 234
chr4_+_74718906 1.63 ENST00000226524.3
platelet factor 4 variant 1
chr11_-_119211525 1.61 ENST00000528368.1
C1q and tumor necrosis factor related protein 5
chr22_-_37172191 1.60 ENST00000340630.5
intraflagellar transport 27 homolog (Chlamydomonas)
chr16_+_616995 1.58 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chr21_+_42733870 1.57 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
myxovirus (influenza virus) resistance 2 (mouse)
chr4_-_101111615 1.56 ENST00000273990.2
DNA-damage-inducible transcript 4-like
chr7_-_99679324 1.55 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
zinc finger protein 3
chr6_+_30951487 1.54 ENST00000486149.2
ENST00000376296.3
mucin 21, cell surface associated
chr11_-_34533257 1.54 ENST00000312319.2
E74-like factor 5 (ets domain transcription factor)
chr1_-_157567868 1.52 ENST00000271532.1
Fc receptor-like 4
chr1_+_145549203 1.49 ENST00000355594.4
ENST00000544626.1
ankyrin repeat domain 35
chr3_-_46506563 1.48 ENST00000231751.4
lactotransferrin
chr5_-_13944652 1.48 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr16_-_25122785 1.46 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
chr5_+_139027877 1.45 ENST00000302517.3
CXXC finger protein 5
chr18_+_61575200 1.40 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_+_51318513 1.39 ENST00000332160.4
methyltransferase like 7A
chr16_-_28608364 1.36 ENST00000533150.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_+_66442411 1.36 ENST00000499966.1
long intergenic non-protein coding RNA 920
chr11_-_114271139 1.35 ENST00000325636.4
chromosome 11 open reading frame 71
chr3_-_57530051 1.34 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
dynein, axonemal, heavy chain 12
chr5_-_111093167 1.33 ENST00000446294.2
ENST00000419114.2
neuronal regeneration related protein
chr18_-_52989525 1.32 ENST00000457482.3
transcription factor 4
chr19_+_44645731 1.30 ENST00000426739.2
zinc finger protein 234
chr5_-_42811986 1.28 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr18_-_53068911 1.27 ENST00000537856.3
transcription factor 4
chr11_+_124055923 1.26 ENST00000318666.6
olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chrX_-_10544942 1.25 ENST00000380779.1
midline 1 (Opitz/BBB syndrome)
chr10_-_7513904 1.25 ENST00000420395.1
RP5-1031D4.2
chr18_-_53069419 1.24 ENST00000570177.2
transcription factor 4
chr16_-_3350614 1.24 ENST00000268674.2
tigger transposable element derived 7
chr5_-_111092873 1.22 ENST00000509025.1
ENST00000515855.1
neuronal regeneration related protein
chr7_-_22234381 1.21 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr3_+_197687071 1.18 ENST00000482695.1
ENST00000330198.4
ENST00000419117.1
ENST00000420910.2
ENST00000332636.5
leishmanolysin-like (metallopeptidase M8 family)
chr17_-_63822563 1.14 ENST00000317442.8
centrosomal protein 112kDa
chr11_+_121447469 1.12 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_-_111093406 1.12 ENST00000379671.3
neuronal regeneration related protein
chr2_+_191273052 1.11 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
major facilitator superfamily domain containing 6
chr3_-_161090660 1.10 ENST00000359175.4
serine palmitoyltransferase, small subunit B
chr5_-_42812143 1.09 ENST00000514985.1
selenoprotein P, plasma, 1
chr9_-_119449483 1.08 ENST00000288520.5
ENST00000358637.4
ENST00000341734.4
astrotactin 2
chr6_-_159420780 1.07 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chrX_-_73512411 1.07 ENST00000602576.1
ENST00000429124.1
FTX transcript, XIST regulator (non-protein coding)
chr11_+_1855645 1.06 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr1_+_13521973 1.06 ENST00000327795.5
PRAME family member 21
chr1_-_108231101 1.05 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr12_+_20968608 1.05 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr10_-_13544945 1.03 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr7_+_12610307 1.02 ENST00000297029.5
scinderin
chr19_-_55791431 1.01 ENST00000593263.1
ENST00000376343.3
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_-_10491234 1.01 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
tyrosine kinase 2
chr16_-_1429627 0.98 ENST00000248104.7
unkempt family zinc finger-like
chr4_+_154125565 0.98 ENST00000338700.5
tripartite motif containing 2
chr2_+_74648848 0.97 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WD repeat domain 54
chr12_-_57522813 0.96 ENST00000556155.1
signal transducer and activator of transcription 6, interleukin-4 induced
chr14_-_75530693 0.96 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
acylphosphatase 1, erythrocyte (common) type
chr19_-_23578220 0.96 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
zinc finger protein 91
chr6_-_31681839 0.96 ENST00000409239.1
ENST00000461287.1
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr1_-_54872059 0.95 ENST00000371320.3
single stranded DNA binding protein 3
chr6_-_47277634 0.94 ENST00000296861.2
tumor necrosis factor receptor superfamily, member 21
chr11_-_77791156 0.93 ENST00000281031.4
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr2_+_198570081 0.93 ENST00000282276.6
methionyl-tRNA synthetase 2, mitochondrial
chr4_-_123843597 0.92 ENST00000510735.1
ENST00000304430.5
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr17_+_32646055 0.92 ENST00000394620.1
chemokine (C-C motif) ligand 8
chr6_+_159291090 0.92 ENST00000367073.4
ENST00000608817.1
chromosome 6 open reading frame 99
chr1_-_27998689 0.92 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
interferon, alpha-inducible protein 6
chr1_+_22351977 0.91 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
long intergenic non-protein coding RNA 339
chr6_+_88299833 0.90 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
origin recognition complex, subunit 3
chr6_-_152489484 0.89 ENST00000354674.4
ENST00000539504.1
spectrin repeat containing, nuclear envelope 1
chr10_-_100174900 0.89 ENST00000370575.4
pyridine nucleotide-disulphide oxidoreductase domain 2
chr5_+_130506475 0.89 ENST00000379380.4
LYR motif containing 7
chr8_+_110099653 0.88 ENST00000311762.2
thyrotropin-releasing hormone receptor
chr2_+_74781828 0.88 ENST00000340004.6
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr11_+_66276550 0.87 ENST00000419755.3
Bardet-Biedl syndrome 1 protein
chr1_+_13742808 0.85 ENST00000602960.1
PRAME family member 20
chr7_+_63774321 0.85 ENST00000423484.2
zinc finger protein 736
chr17_+_30771279 0.84 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_-_109330702 0.83 ENST00000356644.7
sestrin 1
chr19_+_41816053 0.83 ENST00000269967.3
coiled-coil domain containing 97
chr4_+_40337340 0.82 ENST00000310169.2
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr22_-_20461786 0.82 ENST00000426804.1
RIMS binding protein 3
chr16_+_14802801 0.80 ENST00000526520.1
ENST00000531598.2
nuclear pore complex interacting protein family, member A3
chrX_+_30260054 0.80 ENST00000378982.2
melanoma antigen family B, 4
chr6_+_27215471 0.79 ENST00000421826.2
protease, serine, 16 (thymus)
chr12_-_91573132 0.79 ENST00000550563.1
ENST00000546370.1
decorin
chr6_+_126112001 0.79 ENST00000392477.2
nuclear receptor coactivator 7
chr19_-_39421377 0.78 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
seryl-tRNA synthetase 2, mitochondrial
chr22_-_27014043 0.76 ENST00000215939.2
crystallin, beta B1
chr1_-_166845515 0.76 ENST00000367874.4
transcriptional adaptor 1
chr3_-_150264272 0.75 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr11_+_118978045 0.75 ENST00000336702.3
C2CD2-like
chr18_-_52989217 0.75 ENST00000570287.2
transcription factor 4
chr2_-_219858123 0.75 ENST00000453769.1
ENST00000295728.2
ENST00000392096.2
crystallin, beta A2
chr9_+_71939488 0.74 ENST00000455972.1
family with sequence similarity 189, member A2
chr9_-_130639997 0.74 ENST00000373176.1
adenylate kinase 1
chr14_+_55590646 0.73 ENST00000553493.1
lectin, galactoside-binding, soluble, 3
chr2_-_174828892 0.71 ENST00000418194.2
Sp3 transcription factor
chr18_-_53257027 0.70 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
transcription factor 4
chr4_-_1670632 0.70 ENST00000461064.1
family with sequence similarity 53, member A
chr7_+_89975979 0.69 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTP-binding protein 10 (putative)
chr6_-_43197189 0.69 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr13_+_108921977 0.68 ENST00000430559.1
ENST00000375887.4
tumor necrosis factor (ligand) superfamily, member 13b
chr13_-_53024725 0.68 ENST00000378060.4
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr2_+_128458514 0.67 ENST00000310981.4
SFT2 domain containing 3
chrX_+_102883887 0.67 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chr5_+_99871004 0.66 ENST00000312637.4
family with sequence similarity 174, member A
chr3_-_125802765 0.66 ENST00000514891.1
ENST00000512470.1
ENST00000504035.1
ENST00000360370.4
ENST00000513723.1
ENST00000510651.1
ENST00000514333.1
solute carrier family 41, member 3
chr21_+_17909594 0.66 ENST00000441820.1
ENST00000602280.1
long intergenic non-protein coding RNA 478
chr12_+_133613937 0.66 ENST00000539354.1
ENST00000542874.1
ENST00000438628.2
zinc finger protein 84
chr22_-_19435209 0.65 ENST00000546308.1
ENST00000541063.1
ENST00000399568.1
ENST00000333059.5
histone cell cycle regulator
chromosome 22 open reading frame 39
chr7_+_100199800 0.65 ENST00000223061.5
procollagen C-endopeptidase enhancer
chr7_-_5465045 0.65 ENST00000399434.2
trinucleotide repeat containing 18
chr19_+_37837185 0.65 ENST00000541583.2
HKR1, GLI-Kruppel zinc finger family member
chr7_+_139025875 0.64 ENST00000297534.6
chromosome 7 open reading frame 55
chr5_+_89854595 0.64 ENST00000405460.2
G protein-coupled receptor 98
chr22_-_21905750 0.64 ENST00000433039.1
RIMS binding protein 3C
chr10_-_44144292 0.64 ENST00000374433.2
zinc finger protein 32
chrX_+_129473916 0.64 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr17_-_79166176 0.63 ENST00000571292.1
5-azacytidine induced 1
chr4_-_140222358 0.62 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr6_-_28220002 0.62 ENST00000377294.2
zinc finger with KRAB and SCAN domains 4
chr2_+_163200848 0.62 ENST00000233612.4
grancalcin, EF-hand calcium binding protein
chr5_-_111093081 0.62 ENST00000453526.2
ENST00000509427.1
neuronal regeneration related protein
chr5_-_111093340 0.62 ENST00000508870.1
neuronal regeneration related protein
chr18_-_40695604 0.62 ENST00000590910.1
ENST00000326695.5
ENST00000589109.1
ENST00000282028.4
Ras-like without CAAX 2
chr3_-_142720267 0.61 ENST00000597953.1
RP11-91G21.1
chr5_+_110409012 0.61 ENST00000379706.4
thymic stromal lymphopoietin
chr3_-_3221358 0.61 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr1_-_207095212 0.60 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr11_+_60048129 0.60 ENST00000355131.3
membrane-spanning 4-domains, subfamily A, member 4A
chr13_+_108922228 0.60 ENST00000542136.1
tumor necrosis factor (ligand) superfamily, member 13b
chr10_+_82300575 0.59 ENST00000313455.4
SH2 domain containing 4B
chr2_+_163200598 0.59 ENST00000437150.2
ENST00000453113.2
grancalcin, EF-hand calcium binding protein
chr8_-_95220775 0.58 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr11_+_60048004 0.58 ENST00000532114.1
membrane-spanning 4-domains, subfamily A, member 4A
chr7_+_75911902 0.58 ENST00000413003.1
serine/arginine repetitive matrix 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFF_MAFG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 13.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.4 5.6 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.1 3.3 GO:0033212 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
1.1 4.4 GO:0030185 nitric oxide transport(GO:0030185)
0.9 3.5 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.8 2.5 GO:0003099 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.7 5.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.4 1.1 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4 7.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.3 1.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 0.9 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.3 1.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 0.9 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 3.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.3 0.8 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.3 1.5 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.3 1.3 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.2 1.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 2.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 1.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.2 28.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 1.7 GO:0070269 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.2 0.9 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 8.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.5 GO:0036446 peptidyl-serine ADP-ribosylation(GO:0018312) myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.7 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521)
0.1 2.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.6 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 1.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.6 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.9 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.1 0.6 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.9 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.4 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 0.5 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.4 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.5 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 1.5 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0015074 DNA integration(GO:0015074)
0.1 2.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 1.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 6.1 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.1 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.9 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.7 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 0.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.2 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.5 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 1.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 7.6 GO:0022900 electron transport chain(GO:0022900)
0.0 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.0 3.7 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.3 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 13.4 GO:0007018 microtubule-based movement(GO:0007018)
0.0 5.4 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 2.8 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 3.5 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 2.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 5.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.4 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 1.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 1.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 4.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 4.8 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 0.6 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.3 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.7 13.3 GO:0036038 MKS complex(GO:0036038)
0.6 6.6 GO:0036157 outer dynein arm(GO:0036157)
0.5 3.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.5 3.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 29.2 GO:0005844 polysome(GO:0005844)
0.3 3.1 GO:0097433 dense body(GO:0097433)
0.3 0.9 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 6.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 5.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 0.9 GO:0000814 ESCRT II complex(GO:0000814)
0.3 1.1 GO:0060187 cell pole(GO:0060187)
0.2 0.6 GO:0097447 dendritic tree(GO:0097447)
0.2 0.8 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 11.1 GO:0030286 dynein complex(GO:0030286)
0.2 1.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 2.5 GO:0035253 ciliary rootlet(GO:0035253)
0.2 0.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 3.3 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 3.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 2.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130) clathrin complex(GO:0071439)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 4.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
1.5 5.9 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.9 7.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.9 5.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.8 2.5 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.8 3.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.5 1.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 10.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 5.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 2.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 29.7 GO:0019843 rRNA binding(GO:0019843)
0.3 3.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.3 1.8 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.3 1.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.3 0.8 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 6.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 6.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 1.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 2.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 0.8 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 1.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 6.0 GO:0042605 peptide antigen binding(GO:0042605)
0.2 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.8 GO:0070728 leucine binding(GO:0070728)
0.1 0.5 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 1.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 3.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.2 GO:0016248 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.1 0.8 GO:0043559 insulin binding(GO:0043559)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.7 GO:0019863 IgE binding(GO:0019863)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 3.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 4.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 2.9 GO:0019894 kinesin binding(GO:0019894)
0.1 2.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.9 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 2.5 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 3.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.5 GO:0008289 lipid binding(GO:0008289)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 1.1 GO:0030276 calcium-dependent phospholipid binding(GO:0005544) clathrin binding(GO:0030276)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 2.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 1.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 7.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 5.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 29.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 6.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 6.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 5.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 3.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL