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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MAX_TFEB

Z-value: 0.62

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Transcription factors associated with MAX_TFEB

Gene Symbol Gene ID Gene Info
MAX
ENSG00000125952.14 MYC associated factor X
TFEB
ENSG00000112561.13 transcription factor EB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFEBhg19_v2_chr6_-_41703952_417039970.173.6e-01Click!
MAXhg19_v2_chr14_-_65569186_65569243-0.125.2e-01Click!

Activity profile of MAX_TFEB motif

Sorted Z-values of MAX_TFEB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_7137582 2.04 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr12_+_50355647 1.41 ENST00000293599.6
AQP5
aquaporin 5
chr17_-_7137857 1.31 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr19_-_10764509 1.15 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr9_-_124976185 1.10 ENST00000464484.2
LHX6
LIM homeobox 6
chr3_-_19988462 1.00 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr7_+_116593568 0.99 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr5_+_133706865 0.95 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr7_+_116593433 0.92 ENST00000323984.3
ENST00000393449.1
ST7
suppression of tumorigenicity 7
chrX_-_34675391 0.91 ENST00000275954.3
TMEM47
transmembrane protein 47
chr5_-_121413974 0.90 ENST00000231004.4
LOX
lysyl oxidase
chr9_-_124976154 0.88 ENST00000482062.1
LHX6
LIM homeobox 6
chr1_-_154193009 0.80 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43
chromosome 1 open reading frame 43
chr1_-_154193091 0.77 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43
chromosome 1 open reading frame 43
chr8_+_75896731 0.74 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr2_-_133427767 0.73 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr3_-_197686847 0.73 ENST00000265239.6
IQCG
IQ motif containing G
chr7_+_155090271 0.72 ENST00000476756.1
INSIG1
insulin induced gene 1
chr6_+_123110465 0.69 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr9_-_90589586 0.68 ENST00000325303.8
ENST00000375883.3
CDK20
cyclin-dependent kinase 20
chr9_-_90589402 0.67 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20
cyclin-dependent kinase 20
chr7_+_106685079 0.67 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_-_207119738 0.65 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr6_+_123110302 0.63 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr14_-_20923195 0.63 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr7_+_36429424 0.61 ENST00000396068.2
ANLN
anillin, actin binding protein
chr17_+_72270380 0.60 ENST00000582036.1
ENST00000307504.5
DNAI2
dynein, axonemal, intermediate chain 2
chr15_+_45315302 0.58 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr6_-_80657292 0.57 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr12_+_122356488 0.56 ENST00000397454.2
WDR66
WD repeat domain 66
chr10_+_69644404 0.56 ENST00000212015.6
SIRT1
sirtuin 1
chr12_-_2986107 0.56 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
FOXM1
forkhead box M1
chr7_+_36429409 0.55 ENST00000265748.2
ANLN
anillin, actin binding protein
chrX_+_55744166 0.55 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr16_+_810728 0.54 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
MSLN
mesothelin
chr19_-_36545128 0.53 ENST00000538849.1
THAP8
THAP domain containing 8
chr11_+_65479702 0.53 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5
K(lysine) acetyltransferase 5
chr1_-_42921915 0.52 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr17_+_72270429 0.51 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr1_+_154193325 0.51 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr15_+_44084040 0.50 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr19_-_11545920 0.50 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chrX_+_30671476 0.50 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK
glycerol kinase
chr11_-_85779786 0.50 ENST00000356360.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chrX_+_55744228 0.49 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr12_-_65153175 0.49 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
GNS
glucosamine (N-acetyl)-6-sulfatase
chr16_+_84178874 0.49 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chrY_+_15016013 0.48 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr15_+_82555125 0.47 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr20_+_37590942 0.46 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr11_+_65479462 0.45 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5
K(lysine) acetyltransferase 5
chr7_+_150065879 0.45 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
REPIN1
ZNF775
replication initiator 1
zinc finger protein 775
chr16_-_4897266 0.45 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr7_-_155089251 0.45 ENST00000609974.1
AC144652.1
AC144652.1
chr1_-_204329013 0.45 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr2_-_10587897 0.45 ENST00000405333.1
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr19_+_1067271 0.44 ENST00000536472.1
ENST00000590214.1
HMHA1
histocompatibility (minor) HA-1
chr17_-_35969409 0.44 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr16_-_15736953 0.44 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
KIAA0430
chr7_-_122526499 0.43 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr2_-_220108309 0.43 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr14_+_96858433 0.42 ENST00000267584.4
AK7
adenylate kinase 7
chr10_-_90342947 0.42 ENST00000437752.1
ENST00000331772.4
RNLS
renalase, FAD-dependent amine oxidase
chr6_+_87865262 0.42 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr14_-_94443105 0.41 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chrX_+_102883887 0.41 ENST00000372625.3
ENST00000372624.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr9_-_97356075 0.41 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr1_-_3816779 0.40 ENST00000361605.3
C1orf174
chromosome 1 open reading frame 174
chrX_-_13835147 0.40 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr16_+_5083950 0.40 ENST00000588623.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr6_+_7590413 0.40 ENST00000342415.5
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chrX_+_108780347 0.40 ENST00000372103.1
NXT2
nuclear transport factor 2-like export factor 2
chr3_-_17783990 0.39 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5
TBC1 domain family, member 5
chr20_+_47538357 0.39 ENST00000371917.4
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr11_+_7534999 0.39 ENST00000528947.1
ENST00000299492.4
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_+_63706444 0.38 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr11_+_18343800 0.38 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr10_-_93392811 0.38 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr7_+_100464760 0.38 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr16_-_67517716 0.38 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr10_+_101542462 0.38 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_-_109656439 0.37 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr14_-_75536182 0.37 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr11_+_18344106 0.37 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr19_+_1067144 0.37 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr4_-_47465666 0.36 ENST00000381571.4
COMMD8
COMM domain containing 8
chr8_-_81083731 0.36 ENST00000379096.5
TPD52
tumor protein D52
chr7_+_44646162 0.35 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr4_+_15480828 0.35 ENST00000389652.5
CC2D2A
coiled-coil and C2 domain containing 2A
chr16_+_699319 0.35 ENST00000549091.1
ENST00000293879.4
WDR90
WD repeat domain 90
chr11_-_85779971 0.35 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chrX_+_108779870 0.34 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_-_51425902 0.34 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr14_+_77564440 0.34 ENST00000361786.2
ENST00000555437.1
ENST00000555611.1
ENST00000554658.1
KIAA1737
CLOCK-interacting pacemaker
chr19_+_1067492 0.34 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr6_-_43337180 0.33 ENST00000318149.3
ENST00000361428.2
ZNF318
zinc finger protein 318
chr8_+_42128812 0.33 ENST00000520810.1
ENST00000416505.2
ENST00000519735.1
ENST00000520835.1
ENST00000379708.3
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr1_+_222885884 0.33 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr5_+_43603229 0.33 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr7_-_56118981 0.33 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH
phosphoserine phosphatase
chr15_-_50978965 0.33 ENST00000560955.1
ENST00000313478.7
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chrX_+_102883620 0.33 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr2_-_148778323 0.32 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chrX_+_102840408 0.32 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr6_+_160221293 0.32 ENST00000610273.1
ENST00000392167.3
PNLDC1
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr14_-_35591433 0.31 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr9_+_92219919 0.31 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr7_-_56119156 0.31 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr12_+_53662110 0.31 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr2_-_176866978 0.31 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
KIAA1715
chr21_-_36421401 0.30 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr10_-_61666267 0.30 ENST00000263102.6
CCDC6
coiled-coil domain containing 6
chr3_-_45883558 0.30 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr6_-_144329531 0.30 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr6_-_109703600 0.30 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr7_+_130126012 0.29 ENST00000341441.5
MEST
mesoderm specific transcript
chr2_+_46926326 0.29 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr17_+_42977122 0.29 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
FAM187A
CCDC103
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr12_+_28343365 0.29 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chr12_+_133613878 0.29 ENST00000392319.2
ENST00000543758.1
ZNF84
zinc finger protein 84
chr6_+_42018614 0.29 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr14_-_54955721 0.29 ENST00000554908.1
GMFB
glia maturation factor, beta
chr19_-_48018203 0.29 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr12_+_2986359 0.29 ENST00000538636.1
ENST00000461997.2
ENST00000489288.2
ENST00000366285.2
ENST00000538700.1
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr2_+_46926048 0.29 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr21_-_36421626 0.28 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr1_-_68962805 0.28 ENST00000370966.5
DEPDC1
DEP domain containing 1
chr13_-_96296944 0.28 ENST00000361396.2
ENST00000376829.2
DZIP1
DAZ interacting zinc finger protein 1
chr7_+_99070527 0.28 ENST00000379724.3
ZNF789
zinc finger protein 789
chr2_-_148778258 0.28 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr9_+_133454943 0.28 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr11_+_67159416 0.28 ENST00000307980.2
ENST00000544620.1
RAD9A
RAD9 homolog A (S. pombe)
chrX_+_100663243 0.28 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr4_-_99850243 0.27 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr3_+_112280857 0.27 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr21_-_36421535 0.27 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr1_-_26233423 0.27 ENST00000357865.2
STMN1
stathmin 1
chr12_+_57624085 0.27 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_68962782 0.27 ENST00000456315.2
DEPDC1
DEP domain containing 1
chr14_+_45553296 0.27 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr9_+_6757634 0.27 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr16_+_70148230 0.27 ENST00000398122.3
ENST00000568530.1
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr17_-_47841485 0.27 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr18_+_21083437 0.26 ENST00000269221.3
ENST00000590868.1
ENST00000592119.1
C18orf8
chromosome 18 open reading frame 8
chr17_-_34890709 0.26 ENST00000544606.1
MYO19
myosin XIX
chr3_-_46904946 0.26 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr15_+_44084503 0.26 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr7_+_130126165 0.26 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr6_-_33385854 0.26 ENST00000488478.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr12_+_53662073 0.26 ENST00000553219.1
ENST00000257934.4
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr2_-_26101374 0.26 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr6_-_31864977 0.26 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr11_+_120894781 0.26 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
TBCEL
tubulin folding cofactor E-like
chr17_+_42148225 0.25 ENST00000591696.1
G6PC3
glucose 6 phosphatase, catalytic, 3
chr18_-_46987000 0.25 ENST00000442713.2
ENST00000269445.6
DYM
dymeclin
chr17_-_34890732 0.25 ENST00000268852.9
MYO19
myosin XIX
chr5_+_43602750 0.25 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr1_+_40627038 0.25 ENST00000372771.4
RLF
rearranged L-myc fusion
chr6_-_158589259 0.25 ENST00000367101.1
ENST00000367104.3
ENST00000367102.2
SERAC1
serine active site containing 1
chr2_+_27805880 0.25 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr1_+_17248418 0.25 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr10_-_32217717 0.25 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12
Rho GTPase activating protein 12
chr1_-_31845914 0.24 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr12_-_122750957 0.24 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chrX_-_13835461 0.24 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chrX_+_73524020 0.24 ENST00000339534.2
ZCCHC13
zinc finger, CCHC domain containing 13
chr8_-_41909496 0.24 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A
K(lysine) acetyltransferase 6A
chr3_-_46904918 0.24 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr10_+_99344071 0.24 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr6_-_33385655 0.24 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr18_+_9136758 0.23 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr11_+_121322832 0.23 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr9_+_133978190 0.23 ENST00000372312.3
AIF1L
allograft inflammatory factor 1-like
chr19_-_45004556 0.23 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chr4_+_39184024 0.23 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19
WD repeat domain 19
chr6_+_116421976 0.23 ENST00000319550.4
ENST00000419791.1
NT5DC1
5'-nucleotidase domain containing 1
chr1_-_45956800 0.23 ENST00000538496.1
TESK2
testis-specific kinase 2
chrX_-_102510126 0.23 ENST00000372685.3
TCEAL8
transcription elongation factor A (SII)-like 8
chrX_-_102510045 0.23 ENST00000360000.4
TCEAL8
transcription elongation factor A (SII)-like 8
chr16_+_69984810 0.23 ENST00000393701.2
ENST00000568461.1
CLEC18A
C-type lectin domain family 18, member A
chr3_+_183967409 0.23 ENST00000324557.4
ENST00000402825.3
ECE2
endothelin converting enzyme 2
chr19_-_46974664 0.23 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chrX_+_108780062 0.23 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr3_+_113465866 0.23 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr12_+_57624119 0.23 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chrX_+_102469997 0.23 ENST00000372695.5
ENST00000372691.3
BEX4
brain expressed, X-linked 4
chr5_-_158636512 0.23 ENST00000424310.2
RNF145
ring finger protein 145
chr9_-_95640218 0.23 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr6_-_163834852 0.22 ENST00000604200.1
CAHM
colon adenocarcinoma hypermethylated (non-protein coding)
chr19_+_7587491 0.22 ENST00000264079.6
MCOLN1
mucolipin 1
chr1_-_166845515 0.22 ENST00000367874.4
TADA1
transcriptional adaptor 1
chr22_-_42343117 0.22 ENST00000407253.3
ENST00000215980.5
CENPM
centromere protein M
chr2_-_55459294 0.22 ENST00000407122.1
ENST00000406437.2
CLHC1
clathrin heavy chain linker domain containing 1
chr1_+_100315613 0.22 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chrX_+_134654540 0.22 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_+_72148614 0.22 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr2_-_26101314 0.22 ENST00000336112.4
ENST00000272341.4
ASXL2
additional sex combs like 2 (Drosophila)
chr17_-_7218403 0.22 ENST00000570780.1
GPS2
G protein pathway suppressor 2
chr3_-_195163803 0.22 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr19_-_46974741 0.22 ENST00000313683.10
ENST00000602246.1
PNMAL1
paraneoplastic Ma antigen family-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MAX_TFEB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 1.2 GO:1904172 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.4 1.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 1.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 0.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 1.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 0.6 GO:0006059 hexitol metabolic process(GO:0006059)
0.2 0.6 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.9 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.5 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 0.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 2.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 1.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.4 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.1 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 2.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.6 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.3 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 1.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.7 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.3 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.1 0.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.1 0.4 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.2 GO:1903564 ciliary basal body organization(GO:0032053) regulation of protein localization to cilium(GO:1903564) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.1 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.6 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0061110 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0055073 cadmium ion homeostasis(GO:0055073) divalent metal ion export(GO:0070839)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0019858 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) cytosine metabolic process(GO:0019858)
0.0 0.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 1.0 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.5 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.1 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:1902683 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.4 GO:1902074 response to salt(GO:1902074)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.5 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 1.1 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.8 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.6 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.0 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0045446 endothelial cell differentiation(GO:0045446)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0070384 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.0 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.0 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.4 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.1 GO:0044268 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696) negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.6 GO:0003341 cilium movement(GO:0003341)
0.0 0.4 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.5 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.0 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.6 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.8 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.6 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 GO:0000243 commitment complex(GO:0000243)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.6 GO:0001534 radial spoke(GO:0001534)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.1 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.9 GO:0070552 BRISC complex(GO:0070552)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.4 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.2 GO:0019034 viral replication complex(GO:0019034)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 3.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) GAIT complex(GO:0097452)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0000805 X chromosome(GO:0000805) Barr body(GO:0001740)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 1.3 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.6 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.5 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.6 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.6 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.8 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 1.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.6 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.4 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 3.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119)
0.1 0.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702) oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103) deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.0 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.8 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.0 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
0.0 0.3 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine