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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MBD2

Z-value: 0.60

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
MBD2
ENSG00000134046.7 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51750948_51751059-0.154.2e-01Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_17659234 1.05 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr20_-_56284816 0.86 ENST00000395819.3
ENST00000341744.3
PMEPA1
prostate transmembrane protein, androgen induced 1
chr19_+_18496957 0.83 ENST00000252809.3
GDF15
growth differentiation factor 15
chr19_+_39904168 0.66 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr6_-_43596899 0.65 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr19_-_19051103 0.60 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr18_+_56530794 0.54 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr12_-_117318788 0.49 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr17_+_17942684 0.45 ENST00000376345.3
GID4
GID complex subunit 4
chr19_+_35491174 0.44 ENST00000317991.5
ENST00000504615.2
GRAMD1A
GRAM domain containing 1A
chr19_+_56152262 0.43 ENST00000325333.5
ENST00000590190.1
ZNF580
zinc finger protein 580
chr14_+_74417192 0.42 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chr2_-_129076151 0.41 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr7_-_94285402 0.39 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr20_-_590944 0.39 ENST00000246080.3
TCF15
transcription factor 15 (basic helix-loop-helix)
chr7_-_94285472 0.39 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr1_-_43232649 0.39 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr3_-_197024394 0.38 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr12_+_122064673 0.38 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr7_-_94285511 0.37 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr14_-_77787198 0.37 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr5_-_72744336 0.36 ENST00000499003.3
FOXD1
forkhead box D1
chr19_+_35491330 0.36 ENST00000411896.2
ENST00000424536.2
GRAMD1A
GRAM domain containing 1A
chr6_+_4776580 0.36 ENST00000397588.3
CDYL
chromodomain protein, Y-like
chr3_-_196295437 0.35 ENST00000429115.1
WDR53
WD repeat domain 53
chr3_-_48471454 0.34 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr10_-_17659357 0.33 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_+_14143728 0.33 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr15_+_40763150 0.33 ENST00000306243.5
ENST00000559991.1
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr3_-_27525865 0.33 ENST00000445684.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr17_-_27278445 0.32 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr3_-_27525826 0.32 ENST00000454389.1
ENST00000440156.1
ENST00000437179.1
ENST00000446700.1
ENST00000455077.1
ENST00000435667.2
ENST00000388777.4
ENST00000425128.2
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr3_-_128206759 0.31 ENST00000430265.2
GATA2
GATA binding protein 2
chr8_+_30241934 0.31 ENST00000538486.1
RBPMS
RNA binding protein with multiple splicing
chr9_+_34989638 0.30 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_-_25012115 0.30 ENST00000446003.1
ARHGAP21
Rho GTPase activating protein 21
chrX_+_68725084 0.30 ENST00000252338.4
FAM155B
family with sequence similarity 155, member B
chr20_-_48532046 0.30 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chrX_-_152939252 0.30 ENST00000340888.3
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr20_-_46415341 0.29 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr14_+_53019993 0.29 ENST00000542169.2
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chr17_+_65374075 0.29 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_-_165325939 0.29 ENST00000342310.3
LMX1A
LIM homeobox transcription factor 1, alpha
chr21_-_44495919 0.28 ENST00000398158.1
CBS
cystathionine-beta-synthase
chr4_-_16228083 0.28 ENST00000399920.3
TAPT1
transmembrane anterior posterior transformation 1
chr6_+_125474992 0.28 ENST00000528193.1
TPD52L1
tumor protein D52-like 1
chr15_+_80215477 0.28 ENST00000542003.1
C15ORF37
C15orf37 protein; Uncharacterized protein
chr14_+_53019822 0.28 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr2_-_54014127 0.27 ENST00000394717.2
GPR75-ASB3
GPR75-ASB3 readthrough
chr2_-_208031542 0.27 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr3_-_196295468 0.27 ENST00000332629.5
ENST00000433160.1
WDR53
WD repeat domain 53
chr11_-_64684672 0.27 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr20_-_46415297 0.27 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr12_-_120554534 0.27 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr17_-_7141490 0.26 ENST00000574236.1
ENST00000572789.1
PHF23
PHD finger protein 23
chr19_-_41222775 0.26 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4
aarF domain containing kinase 4
chr3_+_133292759 0.26 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr15_+_101142722 0.26 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ASB7
ankyrin repeat and SOCS box containing 7
chr3_+_133292851 0.26 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr18_-_31803169 0.26 ENST00000590712.1
NOL4
nucleolar protein 4
chr3_-_98620500 0.26 ENST00000326840.6
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr5_-_180076580 0.26 ENST00000502649.1
FLT4
fms-related tyrosine kinase 4
chr9_+_35829208 0.25 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr7_-_112579869 0.25 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr14_+_21538517 0.25 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr5_+_133861790 0.25 ENST00000395003.1
PHF15
jade family PHD finger 2
chr7_+_73082152 0.25 ENST00000324941.4
ENST00000451519.1
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr6_-_91296737 0.24 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr6_-_91296602 0.24 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr2_+_173292390 0.24 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6
integrin, alpha 6
chr9_+_124413873 0.24 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr17_+_17942594 0.24 ENST00000268719.4
GID4
GID complex subunit 4
chr7_-_19157248 0.23 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr11_+_67056755 0.23 ENST00000511455.2
ENST00000308440.6
ANKRD13D
ankyrin repeat domain 13 family, member D
chr1_-_6545502 0.23 ENST00000535355.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_+_33155525 0.23 ENST00000449224.1
CRTAP
cartilage associated protein
chr2_-_54014055 0.23 ENST00000263634.3
ENST00000406687.1
GPR75-ASB3
GPR75-ASB3 readthrough
chr3_+_88108381 0.23 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr11_+_67056867 0.23 ENST00000514166.1
ANKRD13D
ankyrin repeat domain 13 family, member D
chr14_+_77787227 0.22 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr6_+_125475335 0.22 ENST00000532429.1
ENST00000534199.1
TPD52L1
tumor protein D52-like 1
chr5_+_122847908 0.22 ENST00000511130.2
ENST00000512718.3
CSNK1G3
casein kinase 1, gamma 3
chr11_+_67033881 0.22 ENST00000308595.5
ENST00000526285.1
ADRBK1
adrenergic, beta, receptor kinase 1
chr7_+_94285637 0.21 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr3_-_88108212 0.21 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr18_-_34408802 0.21 ENST00000590842.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr2_+_48541776 0.21 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr2_+_11052054 0.21 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chrX_+_24167746 0.21 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr14_+_21538429 0.20 ENST00000298694.4
ENST00000555038.1
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr16_-_23160591 0.20 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr12_-_120554622 0.20 ENST00000229340.5
RAB35
RAB35, member RAS oncogene family
chr17_-_42441204 0.20 ENST00000293443.7
FAM171A2
family with sequence similarity 171, member A2
chr11_-_68609377 0.20 ENST00000265641.5
ENST00000376618.2
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr11_-_89224488 0.20 ENST00000534731.1
ENST00000527626.1
NOX4
NADPH oxidase 4
chr3_+_133292574 0.19 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr16_-_2059797 0.19 ENST00000563630.1
ZNF598
zinc finger protein 598
chr2_-_219537134 0.19 ENST00000295704.2
RNF25
ring finger protein 25
chr9_+_129376722 0.19 ENST00000526117.1
ENST00000373474.4
ENST00000355497.5
ENST00000425646.2
ENST00000561065.1
LMX1B
LIM homeobox transcription factor 1, beta
chr4_+_2061119 0.19 ENST00000423729.2
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr3_-_48470838 0.19 ENST00000358459.4
ENST00000358536.4
PLXNB1
plexin B1
chrX_+_24167828 0.19 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX
zinc finger protein, X-linked
chr6_-_45983549 0.19 ENST00000544153.1
CLIC5
chloride intracellular channel 5
chr5_+_153570285 0.19 ENST00000425427.2
ENST00000297107.6
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr2_+_46769798 0.19 ENST00000238738.4
RHOQ
ras homolog family member Q
chr2_+_208576259 0.18 ENST00000392209.3
CCNYL1
cyclin Y-like 1
chr10_+_75545391 0.18 ENST00000604524.1
ENST00000605216.1
ENST00000398706.2
ZSWIM8
zinc finger, SWIM-type containing 8
chr11_+_65408273 0.18 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr3_-_149688896 0.18 ENST00000239940.7
PFN2
profilin 2
chr10_-_92617437 0.18 ENST00000336152.3
ENST00000277874.6
ENST00000371719.2
HTR7
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
chr2_+_9346892 0.18 ENST00000281419.3
ENST00000315273.4
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr5_-_171433579 0.18 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr22_-_19419205 0.18 ENST00000340170.4
ENST00000263208.5
HIRA
histone cell cycle regulator
chr17_+_6544356 0.18 ENST00000574838.1
TXNDC17
thioredoxin domain containing 17
chr1_-_247495045 0.18 ENST00000294753.4
ENST00000366498.2
ZNF496
zinc finger protein 496
chr7_-_17980091 0.18 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr3_-_124774802 0.18 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr10_+_75545329 0.18 ENST00000604729.1
ENST00000603114.1
ZSWIM8
zinc finger, SWIM-type containing 8
chr8_+_30241995 0.18 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
RBPMS
RNA binding protein with multiple splicing
chr14_+_102829300 0.17 ENST00000359520.7
TECPR2
tectonin beta-propeller repeat containing 2
chr17_+_6544328 0.17 ENST00000570330.1
TXNDC17
thioredoxin domain containing 17
chr8_-_67525524 0.17 ENST00000517885.1
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr11_-_2160611 0.17 ENST00000416167.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_112930387 0.17 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chrX_-_134049233 0.17 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr18_-_45457192 0.17 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD2
SMAD family member 2
chr5_-_171433819 0.17 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr2_+_173292301 0.17 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6
integrin, alpha 6
chrX_-_152939133 0.16 ENST00000370150.1
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr9_+_35605274 0.16 ENST00000336395.5
TESK1
testis-specific kinase 1
chr1_-_31712401 0.16 ENST00000373736.2
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr10_+_126490354 0.16 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr6_-_99797522 0.16 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr16_+_3019552 0.16 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr12_-_48213568 0.16 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7
histone deacetylase 7
chr16_-_2059748 0.16 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr11_+_35965531 0.16 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr20_-_48532019 0.16 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr19_+_6739662 0.16 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10
thyroid hormone receptor interactor 10
chr10_+_105253661 0.15 ENST00000369780.4
NEURL
neuralized E3 ubiquitin protein ligase 1
chr2_-_220408430 0.15 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr10_-_92617671 0.15 ENST00000371721.3
HTR7
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
chr19_-_17356697 0.15 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr22_+_25348671 0.15 ENST00000406486.4
KIAA1671
KIAA1671
chr12_-_50222187 0.15 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr1_-_160232312 0.15 ENST00000440682.1
DCAF8
DDB1 and CUL4 associated factor 8
chr19_-_10341948 0.15 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr17_+_48638371 0.15 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr15_+_72766651 0.15 ENST00000379887.4
ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
chr11_+_67055986 0.15 ENST00000447274.2
ANKRD13D
ankyrin repeat domain 13 family, member D
chr19_-_11308190 0.15 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2
KN motif and ankyrin repeat domains 2
chr16_+_3019246 0.15 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr1_-_156252590 0.15 ENST00000361813.5
ENST00000368267.5
SMG5
SMG5 nonsense mediated mRNA decay factor
chr3_+_120461484 0.15 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa
chr19_-_11373128 0.15 ENST00000294618.7
DOCK6
dedicator of cytokinesis 6
chr11_+_65383227 0.14 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr20_-_30311703 0.14 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1
BCL2-like 1
chr12_+_27396901 0.14 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr20_-_30310797 0.14 ENST00000422920.1
BCL2L1
BCL2-like 1
chr14_-_99737822 0.14 ENST00000345514.2
ENST00000443726.2
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr1_-_154531095 0.14 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr17_+_48133459 0.14 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_-_4124079 0.14 ENST00000394867.4
ENST00000262948.5
MAP2K2
mitogen-activated protein kinase kinase 2
chr11_+_66025938 0.13 ENST00000394066.2
KLC2
kinesin light chain 2
chr20_-_50808236 0.13 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein
chr17_+_65373531 0.13 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_+_3689325 0.13 ENST00000444870.2
ENST00000452264.1
SMIM1
small integral membrane protein 1 (Vel blood group)
chr1_+_4714792 0.13 ENST00000378190.3
AJAP1
adherens junctions associated protein 1
chr12_+_107168418 0.13 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr19_-_17137625 0.13 ENST00000443236.1
ENST00000388925.4
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr5_+_153570319 0.13 ENST00000377661.2
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr5_+_176237478 0.13 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr19_+_50353944 0.13 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
PTOV1
prostate tumor overexpressed 1
chrX_+_9983602 0.13 ENST00000380861.4
WWC3
WWC family member 3
chr11_+_111473108 0.12 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr20_-_61885826 0.12 ENST00000370316.3
NKAIN4
Na+/K+ transporting ATPase interacting 4
chr7_-_103848405 0.12 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
ORC5
origin recognition complex, subunit 5
chr12_-_124457257 0.12 ENST00000545891.1
CCDC92
coiled-coil domain containing 92
chr11_-_89224508 0.12 ENST00000525196.1
NOX4
NADPH oxidase 4
chr17_-_27949911 0.12 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr19_+_56154913 0.12 ENST00000270451.5
ENST00000588537.1
ZNF581
zinc finger protein 581
chr2_-_9695847 0.12 ENST00000310823.3
ENST00000497134.1
ADAM17
ADAM metallopeptidase domain 17
chr3_+_49591881 0.12 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr17_+_46126135 0.12 ENST00000361665.3
ENST00000585062.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr10_+_128593978 0.12 ENST00000280333.6
DOCK1
dedicator of cytokinesis 1
chr14_-_102829051 0.12 ENST00000536961.2
ENST00000541568.2
ENST00000216756.6
CINP
cyclin-dependent kinase 2 interacting protein
chr19_-_2151523 0.11 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
AP3D1
adaptor-related protein complex 3, delta 1 subunit
chr1_-_200379129 0.11 ENST00000367353.1
ZNF281
zinc finger protein 281
chr2_+_219824357 0.11 ENST00000302625.4
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr6_+_1610681 0.11 ENST00000380874.2
FOXC1
forkhead box C1
chr12_+_29542557 0.11 ENST00000550906.1
OVCH1-AS1
OVCH1 antisense RNA 1
chr17_+_80477571 0.11 ENST00000335255.5
FOXK2
forkhead box K2
chr11_+_43380459 0.11 ENST00000299240.6
ENST00000039989.4
TTC17
tetratricopeptide repeat domain 17
chr5_-_156569850 0.11 ENST00000524219.1
HAVCR2
hepatitis A virus cellular receptor 2
chr2_+_220299547 0.11 ENST00000312358.7
SPEG
SPEG complex locus
chr2_+_171785824 0.11 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr11_-_73471655 0.11 ENST00000400470.2
RAB6A
RAB6A, member RAS oncogene family
chr6_+_84569359 0.11 ENST00000369681.5
ENST00000369679.4
CYB5R4
cytochrome b5 reductase 4
chr12_+_107168342 0.11 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr15_+_83654950 0.10 ENST00000304191.3
FAM103A1
family with sequence similarity 103, member A1

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.3 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 0.4 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.2 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.9 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.0 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.2 GO:1900224 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of lymphangiogenesis(GO:1901491) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0002519 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.8 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048) midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0022009 chronological cell aging(GO:0001300) establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)