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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MEF2B

Z-value: 0.75

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Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
MEF2B
ENSG00000213999.11 myocyte enhancer factor 2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Bhg19_v2_chr19_-_19302931_193029740.048.1e-01Click!

Activity profile of MEF2B motif

Sorted Z-values of MEF2B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_131200810 1.85 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chr2_+_233497931 1.49 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr12_-_111358372 1.46 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr8_+_1993173 1.27 ENST00000523438.1
MYOM2
myomesin 2
chr8_+_1993152 1.25 ENST00000262113.4
MYOM2
myomesin 2
chr2_-_86564776 1.11 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr6_+_123038689 1.04 ENST00000354275.2
ENST00000368446.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr18_+_12407895 0.97 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr8_-_27115931 0.95 ENST00000523048.1
STMN4
stathmin-like 4
chrX_-_63450480 0.89 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr4_+_120056939 0.88 ENST00000307128.5
MYOZ2
myozenin 2
chr17_+_42248063 0.85 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr11_-_84634217 0.77 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chr11_-_84634447 0.76 ENST00000532653.1
DLG2
discs, large homolog 2 (Drosophila)
chr16_+_84328252 0.74 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr8_-_72268968 0.73 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr16_+_84328429 0.73 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr8_-_72268889 0.72 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr3_-_52486841 0.71 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr3_+_159570722 0.70 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_-_211168332 0.70 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr4_+_8321882 0.69 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
chr1_-_23751189 0.66 ENST00000374601.3
ENST00000450454.2
TCEA3
transcription elongation factor A (SII), 3
chr3_+_8543533 0.63 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_179370517 0.60 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr4_+_37892682 0.59 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr18_-_47792851 0.59 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr11_-_47399942 0.54 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_+_138067521 0.54 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr5_-_16509101 0.53 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr7_-_113559104 0.52 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr14_-_102704783 0.52 ENST00000522534.1
MOK
MOK protein kinase
chr11_-_47400078 0.52 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr14_+_76776957 0.51 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr2_+_170366203 0.50 ENST00000284669.1
KLHL41
kelch-like family member 41
chr14_-_94421923 0.50 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chr6_+_44194762 0.49 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr3_+_49057876 0.47 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr22_+_32340481 0.47 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr22_+_32340447 0.44 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr3_-_192445289 0.44 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr14_-_70546897 0.43 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
SLC8A3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr1_+_212782012 0.43 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr7_+_143013198 0.43 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr17_-_39211463 0.42 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr20_+_44657845 0.38 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr5_-_150521192 0.38 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr19_-_51220176 0.38 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr8_+_11351494 0.37 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr12_-_371994 0.37 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr1_+_84630367 0.37 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_-_137834436 0.37 ENST00000327532.2
ENST00000467030.1
DZIP1L
DAZ interacting zinc finger protein 1-like
chr8_+_11351876 0.36 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr3_+_8543393 0.36 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chrX_-_142722897 0.36 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr14_-_22005343 0.36 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chrX_-_15332665 0.34 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr7_-_37488834 0.34 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr3_-_57326704 0.32 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr15_+_100106244 0.30 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr20_+_44035847 0.30 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_+_7597639 0.29 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_116311402 0.29 ENST00000261448.5
CASQ2
calsequestrin 2 (cardiac muscle)
chr15_+_100106155 0.28 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
MEF2A
myocyte enhancer factor 2A
chr5_-_131347306 0.28 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6
acyl-CoA synthetase long-chain family member 6
chr15_+_100106126 0.27 ENST00000558812.1
ENST00000338042.6
MEF2A
myocyte enhancer factor 2A
chr12_-_45269430 0.27 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr1_+_167063282 0.25 ENST00000361200.2
DUSP27
dual specificity phosphatase 27 (putative)
chr9_+_116327326 0.25 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr10_+_118350468 0.25 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr1_+_156095951 0.25 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr10_+_118350522 0.24 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr3_+_54157480 0.24 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr5_+_132009675 0.24 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr1_+_90098606 0.22 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr6_-_137314371 0.22 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
RP11-55K22.5
chr10_-_69455873 0.22 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr11_-_19223523 0.22 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr7_-_105332084 0.21 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr1_+_145413268 0.20 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chr12_-_5352315 0.20 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr5_+_155753745 0.19 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr3_+_8543561 0.18 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr6_-_33160231 0.18 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr3_+_138067666 0.18 ENST00000475711.1
ENST00000464896.1
MRAS
muscle RAS oncogene homolog
chr9_-_85882145 0.17 ENST00000328788.1
FRMD3
FERM domain containing 3
chr1_-_150693318 0.17 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr7_-_16872932 0.17 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr7_+_30951461 0.17 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr4_-_143227088 0.16 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr5_-_131347583 0.16 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr20_+_11898507 0.15 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr17_+_20059302 0.15 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr12_+_25205446 0.15 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr18_-_3219847 0.14 ENST00000261606.7
MYOM1
myomesin 1
chr5_+_53751445 0.14 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr12_+_25205568 0.14 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr3_+_138067314 0.14 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr12_+_25205666 0.14 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr11_+_1860682 0.13 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr4_-_143767428 0.13 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr11_+_1860200 0.13 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr12_+_15699286 0.12 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr2_+_33661382 0.12 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_+_10199468 0.12 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr15_+_40531621 0.11 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr15_+_40531243 0.11 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr8_+_76452097 0.11 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr2_-_190044480 0.11 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr1_-_201391149 0.11 ENST00000555948.1
ENST00000556362.1
TNNI1
troponin I type 1 (skeletal, slow)
chr8_-_95565673 0.11 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
KIAA1429
KIAA1429
chr11_+_1860832 0.10 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr11_-_18034701 0.10 ENST00000265965.5
SERGEF
secretion regulating guanine nucleotide exchange factor
chr6_+_50061315 0.09 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr21_-_42219065 0.08 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr4_-_143226979 0.08 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr2_+_168043793 0.08 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr3_-_113897545 0.07 ENST00000467632.1
DRD3
dopamine receptor D3
chr18_-_3220106 0.07 ENST00000356443.4
ENST00000400569.3
MYOM1
myomesin 1
chr17_-_1389228 0.07 ENST00000438665.2
MYO1C
myosin IC
chr3_+_35683651 0.06 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr6_-_123957942 0.06 ENST00000398178.3
TRDN
triadin
chr17_-_1389419 0.05 ENST00000575158.1
MYO1C
myosin IC
chr2_-_157198860 0.05 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr19_-_16008880 0.05 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr17_-_5322786 0.05 ENST00000225696.4
NUP88
nucleoporin 88kDa
chr2_-_165424973 0.05 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr21_-_33984456 0.05 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
AP000275.65
C21orf59
Uncharacterized protein
chromosome 21 open reading frame 59
chr5_-_131347501 0.05 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr1_-_204329013 0.04 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr9_+_100263912 0.04 ENST00000259365.4
TMOD1
tropomodulin 1
chr16_-_67867749 0.04 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
CENPT
centromere protein T
chr15_+_40226304 0.04 ENST00000559624.1
ENST00000382727.2
ENST00000263791.5
ENST00000560648.1
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
chr1_+_92632542 0.04 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr10_-_96829246 0.04 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr6_+_12007963 0.03 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr1_+_84630645 0.03 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_145524891 0.03 ENST00000369304.3
ITGA10
integrin, alpha 10
chr11_-_88796803 0.03 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr11_-_47400062 0.02 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr22_-_51017084 0.02 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr3_-_176914238 0.02 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr17_-_42200996 0.02 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr18_-_35145728 0.02 ENST00000361795.5
ENST00000603232.1
CELF4
CUGBP, Elav-like family member 4
chr22_-_51016846 0.01 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr6_+_139094657 0.01 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr8_-_70745575 0.01 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_-_31146615 0.01 ENST00000444692.2
ZNF438
zinc finger protein 438
chr16_-_88717482 0.01 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr9_-_74980113 0.01 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr19_+_56713670 0.00 ENST00000534327.1
ZSCAN5C
zinc finger and SCAN domain containing 5C

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 1.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 0.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.7 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.2 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 1.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0050894 determination of affect(GO:0050894)
0.1 0.9 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.1 0.4 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) meiotic recombination checkpoint(GO:0051598)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 1.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 1.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 1.5 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.7 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.5 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 0.0 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.8 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 2.3 GO:0032982 myosin filament(GO:0032982)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 1.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.0 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 0.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.9 GO:0051373 FATZ binding(GO:0051373)
0.1 0.4 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.1 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 1.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins