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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MEF2C

Z-value: 0.71

Motif logo

Transcription factors associated with MEF2C

Gene Symbol Gene ID Gene Info
ENSG00000081189.9 myocyte enhancer factor 2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Chg19_v2_chr5_-_88119580_88119605-0.291.2e-01Click!

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_8543533 3.72 ENST00000454244.1
LIM and cysteine-rich domains 1
chr3_+_8543393 2.66 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr3_+_8543561 2.56 ENST00000397386.3
LIM and cysteine-rich domains 1
chr15_-_70994612 1.97 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_+_143013198 1.44 ENST00000343257.2
chloride channel, voltage-sensitive 1
chr6_+_123038689 1.22 ENST00000354275.2
ENST00000368446.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr4_-_143227088 1.21 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr14_-_94421923 1.15 ENST00000555507.1
ankyrin repeat and SOCS box containing 2
chr7_-_113559104 1.10 ENST00000284601.3
protein phosphatase 1, regulatory subunit 3A
chr12_-_111358372 0.99 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chrX_+_135279179 0.99 ENST00000370676.3
four and a half LIM domains 1
chrX_+_135278908 0.81 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr14_+_76776957 0.77 ENST00000512784.1
estrogen-related receptor beta
chr1_+_74701062 0.74 ENST00000326637.3
TNNI3 interacting kinase
chr3_+_50316458 0.74 ENST00000316436.3
leucine-rich single-pass membrane protein 2
chr3_+_99357319 0.73 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
collagen, type VIII, alpha 1
chr3_+_35683651 0.72 ENST00000187397.4
cAMP-regulated phosphoprotein, 21kDa
chr2_-_235405679 0.69 ENST00000390645.2
ADP-ribosylation factor-like 4C
chr2_-_208031542 0.69 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr3_+_159570722 0.66 ENST00000482804.1
schwannomin interacting protein 1
chr11_+_69924639 0.63 ENST00000538023.1
ENST00000398543.2
anoctamin 1, calcium activated chloride channel
chr1_+_90098606 0.63 ENST00000370454.4
leucine rich repeat containing 8 family, member C
chr6_-_76203454 0.59 ENST00000237172.7
filamin A interacting protein 1
chr19_-_49576198 0.59 ENST00000221444.1
potassium voltage-gated channel, shaker-related subfamily, member 7
chr14_+_24540731 0.58 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
copine VI (neuronal)
chr9_+_116327326 0.57 ENST00000342620.5
regulator of G-protein signaling 3
chr4_-_186697044 0.57 ENST00000437304.2
sorbin and SH3 domain containing 2
chr11_+_1942580 0.56 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chrX_-_50386648 0.55 ENST00000460112.3
shroom family member 4
chr10_-_7513904 0.55 ENST00000420395.1
RP5-1031D4.2
chr2_-_208030647 0.54 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chr11_+_71249071 0.53 ENST00000398534.3
keratin associated protein 5-8
chr3_+_154797877 0.52 ENST00000462745.1
ENST00000493237.1
membrane metallo-endopeptidase
chr1_-_173174681 0.52 ENST00000367718.1
tumor necrosis factor (ligand) superfamily, member 4
chr2_-_190044480 0.49 ENST00000374866.3
collagen, type V, alpha 2
chr1_-_201391149 0.49 ENST00000555948.1
ENST00000556362.1
troponin I type 1 (skeletal, slow)
chr4_+_37892682 0.49 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr6_-_76203345 0.48 ENST00000393004.2
filamin A interacting protein 1
chr8_+_1993152 0.45 ENST00000262113.4
myomesin 2
chr15_+_67418047 0.45 ENST00000540846.2
SMAD family member 3
chr8_+_1993173 0.43 ENST00000523438.1
myomesin 2
chr16_+_12059050 0.42 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr4_-_143767428 0.42 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr10_-_3827417 0.42 ENST00000497571.1
ENST00000542957.1
Kruppel-like factor 6
chr20_-_44519839 0.41 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr15_+_59730348 0.41 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr7_+_129906660 0.40 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr13_-_30881134 0.40 ENST00000380617.3
ENST00000441394.1
katanin p60 subunit A-like 1
chr16_+_12058961 0.39 ENST00000053243.1
tumor necrosis factor receptor superfamily, member 17
chr4_-_57547454 0.39 ENST00000556376.2
HOP homeobox
chr1_-_12677714 0.39 ENST00000376223.2
dehydrogenase/reductase (SDR family) member 3
chr19_-_51220176 0.38 ENST00000359082.3
ENST00000293441.1
SH3 and multiple ankyrin repeat domains 1
chr7_-_121944491 0.38 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr16_+_30075463 0.38 ENST00000562168.1
ENST00000569545.1
aldolase A, fructose-bisphosphate
chr5_-_95018660 0.37 ENST00000395899.3
ENST00000274432.8
spermatogenesis associated 9
chr4_-_57547870 0.36 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr4_+_169418255 0.36 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr1_+_26348259 0.36 ENST00000374280.3
exostosin-like glycosyltransferase 1
chr3_+_138067666 0.36 ENST00000475711.1
ENST00000464896.1
muscle RAS oncogene homolog
chrX_+_18725758 0.36 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr17_-_9694614 0.35 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr2_+_168043793 0.35 ENST00000409273.1
ENST00000409605.1
xin actin-binding repeat containing 2
chr5_-_131347501 0.34 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr7_+_154002189 0.34 ENST00000332007.3
dipeptidyl-peptidase 6
chr3_+_4535155 0.34 ENST00000544951.1
inositol 1,4,5-trisphosphate receptor, type 1
chr17_-_10276319 0.34 ENST00000252172.4
ENST00000418404.3
myosin, heavy chain 13, skeletal muscle
chr7_+_120629653 0.33 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr16_+_30075783 0.33 ENST00000412304.2
aldolase A, fructose-bisphosphate
chr8_-_7309887 0.33 ENST00000458665.1
ENST00000528168.1
sperm associated antigen 11B
chr8_-_49833978 0.33 ENST00000020945.1
snail family zinc finger 2
chr16_+_30075595 0.33 ENST00000563060.2
aldolase A, fructose-bisphosphate
chr3_+_4535025 0.32 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
inositol 1,4,5-trisphosphate receptor, type 1
chr22_-_36031181 0.32 ENST00000594060.1
AL049747.1
chr10_+_71562180 0.32 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
collagen, type XIII, alpha 1
chr11_+_1940925 0.31 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
troponin T type 3 (skeletal, fast)
chr3_-_112360116 0.31 ENST00000206423.3
ENST00000439685.2
coiled-coil domain containing 80
chr3_+_138067521 0.31 ENST00000494949.1
muscle RAS oncogene homolog
chr16_-_31439735 0.30 ENST00000287490.4
cytochrome c oxidase subunit VIa polypeptide 2
chr6_-_123957942 0.30 ENST00000398178.3
triadin
chr5_-_11588907 0.30 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr3_-_108248169 0.30 ENST00000273353.3
myosin, heavy chain 15
chr11_+_1940786 0.30 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
troponin T type 3 (skeletal, fast)
chr7_-_143956815 0.30 ENST00000493325.1
olfactory receptor, family 2, subfamily A, member 7
chr15_+_68582544 0.29 ENST00000566008.1
fem-1 homolog b (C. elegans)
chr11_+_19799327 0.29 ENST00000540292.1
neuron navigator 2
chr2_-_231825668 0.29 ENST00000392039.2
G protein-coupled receptor 55
chr17_-_34625719 0.28 ENST00000422211.2
ENST00000542124.1
chemokine (C-C motif) ligand 3-like 1
chr3_+_138067314 0.28 ENST00000423968.2
muscle RAS oncogene homolog
chr6_+_34204642 0.28 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr3_-_149510553 0.27 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr8_+_107282368 0.27 ENST00000521369.2
RP11-395G23.3
chr2_+_145780739 0.26 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
testis expressed 41 (non-protein coding)
chr3_-_46904918 0.26 ENST00000395869.1
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr11_+_57308979 0.26 ENST00000457912.1
smoothelin-like 1
chr17_-_34524157 0.26 ENST00000378354.4
ENST00000394484.1
chemokine (C-C motif) ligand 3-like 3
chr8_-_49834299 0.26 ENST00000396822.1
snail family zinc finger 2
chr15_-_83474806 0.26 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr3_-_46904946 0.26 ENST00000292327.4
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr7_-_44105158 0.26 ENST00000297283.3
phosphoglycerate mutase 2 (muscle)
chr2_+_182850743 0.25 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr21_+_35552978 0.25 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
long intergenic non-protein coding RNA 310
chr14_-_57277178 0.25 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
orthodenticle homeobox 2
chr1_+_156095951 0.25 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr4_+_37962018 0.25 ENST00000504686.1
pituitary tumor-transforming 2
chr12_-_102874102 0.25 ENST00000392905.2
insulin-like growth factor 1 (somatomedin C)
chr7_+_142457315 0.25 ENST00000486171.1
ENST00000311737.7
protease, serine, 1 (trypsin 1)
chr14_-_57277163 0.25 ENST00000555006.1
orthodenticle homeobox 2
chr10_+_71561630 0.25 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr6_-_123958141 0.25 ENST00000334268.4
triadin
chr3_-_4927447 0.24 ENST00000449914.1
Uncharacterized protein
chr10_+_71561704 0.24 ENST00000520267.1
collagen, type XIII, alpha 1
chr17_-_1389228 0.24 ENST00000438665.2
myosin IC
chr12_-_57644952 0.24 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
SH3 and cysteine rich domain 3
chr11_+_128563652 0.24 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr21_+_17909594 0.24 ENST00000441820.1
ENST00000602280.1
long intergenic non-protein coding RNA 478
chr1_-_100643765 0.24 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
leucine rich repeat containing 39
chr7_+_18535346 0.23 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
histone deacetylase 9
chr17_-_1389419 0.23 ENST00000575158.1
myosin IC
chr19_+_6739662 0.23 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
thyroid hormone receptor interactor 10
chr4_-_143226979 0.22 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr6_-_161085291 0.22 ENST00000316300.5
lipoprotein, Lp(a)
chr10_+_71561649 0.22 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
collagen, type XIII, alpha 1
chr7_-_82073031 0.22 ENST00000356253.5
ENST00000423588.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr14_+_39735411 0.21 ENST00000603904.1
cTAGE family member 5 isoform 4
chr9_-_134585221 0.21 ENST00000372190.3
ENST00000427994.1
Rap guanine nucleotide exchange factor (GEF) 1
chrX_-_30327495 0.21 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr4_-_186696425 0.21 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr5_-_11589131 0.21 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr2_+_148778570 0.21 ENST00000407073.1
methyl-CpG binding domain protein 5
chr5_-_66492562 0.21 ENST00000256447.4
CD180 molecule
chr3_-_137834436 0.20 ENST00000327532.2
ENST00000467030.1
DAZ interacting zinc finger protein 1-like
chr8_-_72268889 0.20 ENST00000388742.4
eyes absent homolog 1 (Drosophila)
chr4_+_55095264 0.20 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr16_+_12059091 0.20 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr7_+_143632259 0.19 ENST00000408955.2
olfactory receptor, family 2, subfamily F, member 2
chrX_-_15683147 0.19 ENST00000380342.3
transmembrane protein 27
chr1_+_230193521 0.19 ENST00000543760.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr7_-_82073109 0.19 ENST00000356860.3
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr8_+_145162629 0.19 ENST00000323662.8
KIAA1875
chr8_-_42234745 0.19 ENST00000220812.2
dickkopf WNT signaling pathway inhibitor 4
chr12_-_40013553 0.19 ENST00000308666.3
ATP-binding cassette, sub-family D (ALD), member 2
chr16_+_84328252 0.19 ENST00000219454.5
WAP four-disulfide core domain 1
chr9_-_215744 0.18 ENST00000382387.2
chromosome 9 open reading frame 66
chr22_-_37215523 0.18 ENST00000216200.5
parvalbumin
chr1_+_198608146 0.18 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr1_-_24438664 0.18 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
myomesin 3
chr8_+_7716700 0.18 ENST00000454911.2
ENST00000326625.5
sperm associated antigen 11A
chr15_+_40531243 0.18 ENST00000558055.1
ENST00000455577.2
p21 protein (Cdc42/Rac)-activated kinase 6
chr9_+_5231413 0.18 ENST00000239316.4
insulin-like 4 (placenta)
chr17_-_79881408 0.18 ENST00000392366.3
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr20_-_54580523 0.18 ENST00000064571.2
cerebellin 4 precursor
chr11_-_85780853 0.18 ENST00000531930.1
ENST00000528398.1
phosphatidylinositol binding clathrin assembly protein
chr17_-_72855989 0.17 ENST00000293190.5
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr19_+_35630344 0.17 ENST00000455515.2
FXYD domain containing ion transport regulator 1
chrX_+_37545012 0.17 ENST00000378616.3
X-linked Kx blood group (McLeod syndrome)
chr6_+_44194762 0.17 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr11_+_1860200 0.17 ENST00000381911.1
troponin I type 2 (skeletal, fast)
chr20_+_44035847 0.16 ENST00000372712.2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr16_+_7382745 0.16 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_+_131157609 0.16 ENST00000496850.1
Serine/threonine-protein kinase MST4
chr3_+_141106643 0.16 ENST00000514251.1
zinc finger and BTB domain containing 38
chr6_+_161123270 0.16 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chrX_+_105192423 0.16 ENST00000540278.1
Nik related kinase
chr10_+_120116527 0.16 ENST00000445161.1
long intergenic non-protein coding RNA 867
chr11_-_47400062 0.16 ENST00000533030.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr10_-_96829246 0.15 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr2_+_30569506 0.15 ENST00000421976.2
AC109642.1
chr1_-_115238207 0.15 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
adenosine monophosphate deaminase 1
chr7_+_18535893 0.15 ENST00000432645.2
ENST00000441542.2
histone deacetylase 9
chr8_-_33457453 0.15 ENST00000523956.1
ENST00000256261.4
dual specificity phosphatase 26 (putative)
chr7_-_124569991 0.15 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
protection of telomeres 1
chr3_+_42727011 0.15 ENST00000287777.4
kelch-like family member 40
chr1_+_145413268 0.15 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
hemochromatosis type 2 (juvenile)
chr4_+_100495864 0.15 ENST00000265517.5
ENST00000422897.2
microsomal triglyceride transfer protein
chr3_+_36421826 0.15 ENST00000273183.3
SH3 and cysteine rich domain
chr3_-_147124547 0.15 ENST00000491672.1
ENST00000383075.3
Zic family member 4
chr15_+_40531621 0.15 ENST00000560346.1
p21 protein (Cdc42/Rac)-activated kinase 6
chr16_+_84328429 0.14 ENST00000568638.1
WAP four-disulfide core domain 1
chr4_+_169418195 0.14 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr10_+_118083919 0.14 ENST00000333254.3
coiled-coil domain containing 172
chr2_-_151344172 0.14 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr22_+_32340447 0.14 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr10_-_29923893 0.14 ENST00000355867.4
supervillin
chr7_+_95115210 0.13 ENST00000428113.1
ENST00000325885.5
ankyrin repeat and SOCS box containing 4
chr3_+_135741576 0.13 ENST00000334546.2
protein phosphatase 2, regulatory subunit B'', alpha
chr12_-_131200810 0.13 ENST00000536002.1
ENST00000544034.1
RIMS binding protein 2
RP11-662M24.2
chr17_+_4855053 0.13 ENST00000518175.1
enolase 3 (beta, muscle)
chr8_-_95565673 0.13 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
KIAA1429
chr10_-_3827371 0.13 ENST00000469435.1
Kruppel-like factor 6
chr3_+_54157480 0.13 ENST00000490478.1
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr12_-_122240792 0.13 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
ras homolog family member F (in filopodia)
chrX_-_109683446 0.13 ENST00000372057.1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr22_+_40342819 0.12 ENST00000407075.3
GRB2-related adaptor protein 2
chr8_-_72268968 0.12 ENST00000388740.3
eyes absent homolog 1 (Drosophila)
chr4_-_71532339 0.12 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr18_-_35145981 0.12 ENST00000420428.2
ENST00000412753.1
CUGBP, Elav-like family member 4
chr1_-_40042416 0.12 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr21_+_39628852 0.12 ENST00000398938.2
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_67584174 0.12 ENST00000320694.8
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr18_-_35145728 0.12 ENST00000361795.5
ENST00000603232.1
CUGBP, Elav-like family member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.5 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 1.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0050894 determination of affect(GO:0050894)
0.1 1.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.5 GO:0046449 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.3 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.2 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.2 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.6 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) meiotic recombination checkpoint(GO:0051598)
0.0 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.4 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0042668 inhibition of neuroepithelial cell differentiation(GO:0002085) trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 2.1 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 1.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 1.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 1.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 1.4 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0051096 telomere assembly(GO:0032202) positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.0 0.3 GO:0010811 regulation of cell-substrate adhesion(GO:0010810) positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 1.0 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.3 GO:0006936 muscle contraction(GO:0006936)
0.0 0.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0032982 myosin filament(GO:0032982)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.7 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.1 1.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 1.7 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3 1.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 9.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0015266 protein channel activity(GO:0015266)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 ST GAQ PATHWAY G alpha q Pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization