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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MEF2D_MEF2A

Z-value: 0.56

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Transcription factors associated with MEF2D_MEF2A

Gene Symbol Gene ID Gene Info
MEF2D
ENSG00000116604.13 myocyte enhancer factor 2D
MEF2A
ENSG00000068305.13 myocyte enhancer factor 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Dhg19_v2_chr1_-_156460391_1564604170.154.3e-01Click!
MEF2Ahg19_v2_chr15_+_100106244_100106292-0.115.6e-01Click!

Activity profile of MEF2D_MEF2A motif

Sorted Z-values of MEF2D_MEF2A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_131200810 1.12 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chr2_+_233497931 0.90 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr7_-_113559104 0.73 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr3_+_35683651 0.66 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_-_121944491 0.60 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr14_+_24540731 0.55 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6
copine VI (neuronal)
chr11_-_19223523 0.53 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr3_+_138067666 0.52 ENST00000475711.1
ENST00000464896.1
MRAS
muscle RAS oncogene homolog
chr17_+_37821593 0.52 ENST00000578283.1
TCAP
titin-cap
chr17_+_34538310 0.51 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr1_-_201391149 0.50 ENST00000555948.1
ENST00000556362.1
TNNI1
troponin I type 1 (skeletal, slow)
chr3_-_108248169 0.49 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr9_-_104145795 0.49 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr1_-_25756638 0.48 ENST00000349320.3
RHCE
Rh blood group, CcEe antigens
chr3_+_138067314 0.47 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr17_-_72855989 0.47 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr3_+_138067521 0.46 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr17_+_34639793 0.45 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr2_-_211168332 0.44 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr17_+_34640031 0.44 ENST00000339270.6
ENST00000482104.1
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr7_+_143013198 0.43 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr8_+_1993152 0.42 ENST00000262113.4
MYOM2
myomesin 2
chr4_-_23891658 0.42 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr17_+_7184986 0.42 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr8_+_1993173 0.42 ENST00000523438.1
MYOM2
myomesin 2
chr12_-_45269430 0.40 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr14_+_76776957 0.39 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr10_-_75415825 0.39 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr11_+_1942580 0.35 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr10_+_118187379 0.35 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chrX_-_21776281 0.35 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr8_+_7716700 0.34 ENST00000454911.2
ENST00000326625.5
SPAG11A
sperm associated antigen 11A
chr6_-_33160231 0.33 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr8_+_95565947 0.33 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr16_-_31439735 0.33 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr14_-_65409502 0.33 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr5_+_155753745 0.32 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr6_-_55739542 0.32 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr1_+_95583479 0.31 ENST00000455656.1
ENST00000604534.1
TMEM56
RP11-57H12.6
transmembrane protein 56
TMEM56-RWDD3 readthrough
chr3_+_99357319 0.31 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr11_+_129245796 0.31 ENST00000281437.4
BARX2
BARX homeobox 2
chr2_+_168043793 0.31 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr2_-_190044480 0.31 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr2_-_165424973 0.30 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr7_+_18535893 0.30 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr9_+_116327326 0.30 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr4_+_120056939 0.30 ENST00000307128.5
MYOZ2
myozenin 2
chr2_-_211179883 0.30 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr1_-_152131703 0.30 ENST00000316073.3
RPTN
repetin
chr13_-_46756351 0.29 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_53751445 0.29 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr10_-_75410771 0.29 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr11_+_128563652 0.28 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_+_88367299 0.26 ENST00000419482.2
ENST00000444564.2
SMYD1
SET and MYND domain containing 1
chr6_+_44194762 0.26 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr2_+_220299547 0.26 ENST00000312358.7
SPEG
SPEG complex locus
chrX_-_15332665 0.25 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr1_+_150254936 0.25 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr17_-_34345002 0.24 ENST00000293280.2
CCL23
chemokine (C-C motif) ligand 23
chr8_-_7309887 0.24 ENST00000458665.1
ENST00000528168.1
SPAG11B
sperm associated antigen 11B
chr17_-_34344991 0.24 ENST00000591423.1
CCL23
chemokine (C-C motif) ligand 23
chr7_-_37488834 0.24 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr14_-_65409438 0.24 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr2_-_31637560 0.23 ENST00000379416.3
XDH
xanthine dehydrogenase
chr15_-_70994612 0.23 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_-_219696519 0.23 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr2_+_33661382 0.23 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_-_76203345 0.23 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr1_-_100643765 0.23 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr18_+_12407895 0.22 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr5_-_16509101 0.22 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr17_+_42248063 0.22 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr17_-_27949911 0.21 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr3_+_8543533 0.21 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr7_+_99775366 0.21 ENST00000394018.2
ENST00000416412.1
STAG3
stromal antigen 3
chr1_-_169703203 0.21 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr19_-_18209626 0.21 ENST00000598019.2
ENST00000594176.1
ENST00000600835.2
IL12RB1
interleukin 12 receptor, beta 1
chr1_+_114522049 0.20 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr15_-_83474806 0.20 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr4_+_37892682 0.20 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr21_-_34186006 0.19 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr1_+_26348259 0.19 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr7_+_99775520 0.19 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3
stromal antigen 3
chr12_-_371994 0.19 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr9_+_129677123 0.19 ENST00000373436.1
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr6_+_123038689 0.19 ENST00000354275.2
ENST00000368446.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr3_+_50316458 0.19 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr16_+_84328252 0.19 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr6_-_76203454 0.19 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr16_+_84328429 0.19 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chrX_+_9217932 0.18 ENST00000432442.1
GS1-519E5.1
GS1-519E5.1
chr17_-_1389228 0.18 ENST00000438665.2
MYO1C
myosin IC
chr2_-_219696511 0.18 ENST00000439262.2
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr12_+_15699286 0.18 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr20_-_44519839 0.17 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr1_+_203097407 0.17 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr1_-_116383322 0.17 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr17_-_10421853 0.17 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_+_145413268 0.17 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chr10_-_3827371 0.17 ENST00000469435.1
KLF6
Kruppel-like factor 6
chr1_+_182584314 0.17 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr8_-_42234745 0.17 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr18_+_13611431 0.16 ENST00000587757.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr11_+_1940925 0.16 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3
troponin T type 3 (skeletal, fast)
chr19_-_47975417 0.16 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr7_+_30951461 0.16 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr4_-_122302163 0.16 ENST00000394427.2
QRFPR
pyroglutamylated RFamide peptide receptor
chrX_+_135570046 0.16 ENST00000370648.3
BRS3
bombesin-like receptor 3
chr1_+_175036966 0.16 ENST00000239462.4
TNN
tenascin N
chr3_+_36421826 0.15 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr6_+_159291090 0.15 ENST00000367073.4
ENST00000608817.1
C6orf99
chromosome 6 open reading frame 99
chr6_+_132129151 0.15 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr1_+_35258592 0.15 ENST00000342280.4
ENST00000450137.1
GJA4
gap junction protein, alpha 4, 37kDa
chr8_+_74903580 0.15 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr11_+_124481361 0.15 ENST00000284288.2
PANX3
pannexin 3
chr6_+_159290917 0.14 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr16_+_12059091 0.14 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr11_-_47400078 0.14 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr7_+_39125365 0.14 ENST00000559001.1
ENST00000464276.2
POU6F2
POU class 6 homeobox 2
chr14_+_39735411 0.14 ENST00000603904.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr15_-_99057551 0.14 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr6_-_45983581 0.14 ENST00000339561.6
CLIC5
chloride intracellular channel 5
chr10_-_45474237 0.14 ENST00000448778.1
ENST00000298295.3
C10orf10
chromosome 10 open reading frame 10
chr4_-_143226979 0.13 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_+_154002189 0.13 ENST00000332007.3
DPP6
dipeptidyl-peptidase 6
chr6_-_27806117 0.13 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr8_+_27183033 0.13 ENST00000420218.2
PTK2B
protein tyrosine kinase 2 beta
chr5_-_150521192 0.13 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chrX_-_63450480 0.13 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr1_-_201390846 0.13 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1
troponin I type 1 (skeletal, slow)
chr8_+_27182862 0.13 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr11_-_62457371 0.13 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr14_+_56046914 0.13 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1
kinectin 1 (kinesin receptor)
chr12_+_81101277 0.13 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr10_+_71562180 0.13 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr9_+_100263912 0.13 ENST00000259365.4
TMOD1
tropomodulin 1
chr13_-_103346854 0.13 ENST00000267273.6
METTL21C
methyltransferase like 21C
chr7_-_105332084 0.13 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr3_+_35721182 0.13 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr20_+_44657845 0.13 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr11_+_57308979 0.12 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr4_+_119809984 0.12 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr4_+_88529681 0.12 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chr12_+_80750134 0.12 ENST00000546620.1
OTOGL
otogelin-like
chrX_-_50386648 0.12 ENST00000460112.3
SHROOM4
shroom family member 4
chr17_-_10325261 0.12 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr18_-_35145728 0.12 ENST00000361795.5
ENST00000603232.1
CELF4
CUGBP, Elav-like family member 4
chr17_-_1389419 0.12 ENST00000575158.1
MYO1C
myosin IC
chr14_-_57277178 0.12 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr18_-_35145981 0.12 ENST00000420428.2
ENST00000412753.1
CELF4
CUGBP, Elav-like family member 4
chrX_+_105192423 0.12 ENST00000540278.1
NRK
Nik related kinase
chr2_+_220144052 0.12 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr1_+_150245177 0.12 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr17_-_38821373 0.12 ENST00000394052.3
KRT222
keratin 222
chr19_+_3933085 0.12 ENST00000168977.2
ENST00000599576.1
NMRK2
nicotinamide riboside kinase 2
chr6_+_136172820 0.12 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr4_+_8321882 0.12 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
chr12_-_45270151 0.12 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr21_+_17909594 0.12 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_111358372 0.11 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr5_-_131347501 0.11 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr11_-_47399942 0.11 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_-_116833500 0.11 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr1_+_151129103 0.11 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr18_-_44181442 0.11 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr6_-_169654139 0.11 ENST00000366787.3
THBS2
thrombospondin 2
chr12_-_99548270 0.11 ENST00000546568.1
ENST00000332712.7
ENST00000546960.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr3_+_8543393 0.11 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr4_+_119810134 0.11 ENST00000434046.2
SYNPO2
synaptopodin 2
chr8_-_27115931 0.11 ENST00000523048.1
STMN4
stathmin-like 4
chr2_+_145780739 0.11 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr2_-_29297127 0.11 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr11_+_112832202 0.11 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr8_-_27850141 0.11 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr7_-_44105158 0.10 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr6_+_152128686 0.10 ENST00000206249.3
ESR1
estrogen receptor 1
chr12_-_45270077 0.10 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr5_+_67584174 0.10 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_-_131347306 0.10 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6
acyl-CoA synthetase long-chain family member 6
chr7_+_123488124 0.10 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr10_+_88428370 0.10 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr17_-_10276319 0.10 ENST00000252172.4
ENST00000418404.3
MYH13
myosin, heavy chain 13, skeletal muscle
chr3_-_57326704 0.10 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr3_+_132843652 0.10 ENST00000508711.1
TMEM108
transmembrane protein 108
chr7_-_27169801 0.10 ENST00000511914.1
HOXA4
homeobox A4
chr14_+_100150622 0.10 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr2_+_220143989 0.10 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr17_-_41132410 0.09 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr17_+_68165657 0.09 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr2_+_204801471 0.09 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr13_+_76210448 0.09 ENST00000377499.5
LMO7
LIM domain 7
chr18_+_13611763 0.09 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr1_-_99470558 0.09 ENST00000370188.3
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr8_-_70745575 0.09 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_+_32856764 0.09 ENST00000375030.2
ENST00000375028.3
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr1_-_23751189 0.09 ENST00000374601.3
ENST00000450454.2
TCEA3
transcription elongation factor A (SII), 3
chr10_-_3827417 0.09 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chr6_+_152128371 0.09 ENST00000443427.1
ESR1
estrogen receptor 1
chr14_-_57277163 0.09 ENST00000555006.1
OTX2
orthodenticle homeobox 2
chr1_+_156211753 0.09 ENST00000368272.4
BGLAP
bone gamma-carboxyglutamate (gla) protein

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.2 0.5 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.2 GO:0090260 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.5 GO:0019530 taurine metabolic process(GO:0019530)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.4 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:1903799 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0033594 response to vitamin K(GO:0032571) response to hydroxyisoflavone(GO:0033594)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 1.2 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.9 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:0033292 T-tubule organization(GO:0033292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.2 GO:0042022 interleukin-12 receptor complex(GO:0042022)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.2 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.8 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0016517 interleukin-12 receptor activity(GO:0016517)
0.1 0.5 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1