Project
Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)
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Results for MYBL2
Z-value: 1.89
Motif logo
Transcription factors associated with MYBL2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MYBL2
|
ENSG00000101057.11 | MYB proto-oncogene like 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYBL2 | hg19_v2_chr20_+_42295745_42295797 | 0.28 | 1.3e-01 | Click! |
Activity profile of MYBL2 motif
Sorted Z-values of MYBL2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MYBL2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 6.5 | GO:1903567 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 1.2 | 4.8 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 1.0 | 4.1 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 1.0 | 7.9 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.9 | 2.8 | GO:0006186 | dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571) |
| 0.9 | 0.9 | GO:1903438 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.8 | 11.6 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.7 | 3.7 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.7 | 2.1 | GO:1900195 | spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195) |
| 0.6 | 3.2 | GO:0090579 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.6 | 1.8 | GO:0050720 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.5 | 9.5 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.4 | 7.4 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.4 | 4.8 | GO:0061525 | hindgut development(GO:0061525) |
| 0.4 | 4.7 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.3 | 1.7 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.3 | 1.0 | GO:0000706 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 0.3 | 2.3 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 0.3 | 1.0 | GO:1904882 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 0.3 | 1.3 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.3 | 0.9 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 0.3 | 1.7 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.3 | 1.1 | GO:0009236 | cobalamin biosynthetic process(GO:0009236) |
| 0.3 | 1.4 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) |
| 0.3 | 2.7 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.2 | 4.2 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.2 | 0.7 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.2 | 0.7 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.2 | 3.0 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.2 | 2.2 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.2 | 0.6 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.2 | 7.5 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.2 | 0.6 | GO:0043012 | regulation of fusion of sperm to egg plasma membrane(GO:0043012) |
| 0.2 | 0.8 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.2 | 0.9 | GO:0031296 | B cell costimulation(GO:0031296) |
| 0.2 | 1.6 | GO:0032621 | interleukin-18 production(GO:0032621) |
| 0.2 | 2.9 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.2 | 0.3 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 0.2 | 0.5 | GO:2000439 | negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439) |
| 0.2 | 0.8 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.2 | 0.5 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.2 | 3.2 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.2 | 3.5 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.1 | 3.4 | GO:0007099 | centriole replication(GO:0007099) |
| 0.1 | 0.9 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 0.6 | GO:0070352 | positive regulation of white fat cell proliferation(GO:0070352) |
| 0.1 | 1.3 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.1 | 0.8 | GO:1903238 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) positive regulation of leukocyte tethering or rolling(GO:1903238) |
| 0.1 | 0.5 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 0.1 | 0.4 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 0.1 | 0.9 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 1.0 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 1.4 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 0.5 | GO:0006581 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
| 0.1 | 4.7 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.1 | 1.9 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 0.3 | GO:0002728 | negative regulation of natural killer cell cytokine production(GO:0002728) |
| 0.1 | 0.7 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.1 | 1.5 | GO:0009650 | UV protection(GO:0009650) |
| 0.1 | 0.9 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.1 | 0.7 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.1 | 1.1 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.1 | 1.1 | GO:0015747 | urate transport(GO:0015747) |
| 0.1 | 0.3 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.1 | 0.7 | GO:0021564 | vagus nerve development(GO:0021564) |
| 0.1 | 0.3 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.1 | 0.3 | GO:0009224 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.1 | 0.2 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 0.1 | 0.6 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) |
| 0.1 | 0.2 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.1 | 2.1 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 0.4 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.1 | 1.4 | GO:0000022 | mitotic spindle elongation(GO:0000022) |
| 0.1 | 0.7 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.1 | 0.4 | GO:1904098 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.1 | 0.5 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.1 | 1.1 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 0.3 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 0.4 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.1 | 1.3 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.1 | 0.3 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.1 | 0.2 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.1 | 0.3 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 0.1 | 1.2 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.1 | 7.5 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.1 | 0.4 | GO:0090084 | inclusion body assembly(GO:0070841) regulation of inclusion body assembly(GO:0090083) negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.2 | GO:0010748 | response to high light intensity(GO:0009644) regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) cellular response to light intensity(GO:0071484) |
| 0.1 | 1.3 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.1 | 1.1 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.1 | 1.3 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) |
| 0.1 | 0.3 | GO:1901911 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 1.0 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.1 | 0.4 | GO:0051177 | meiotic sister chromatid cohesion(GO:0051177) |
| 0.1 | 2.5 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.1 | 0.5 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.1 | 0.6 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 1.1 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.1 | 0.3 | GO:0032466 | negative regulation of cytokinesis(GO:0032466) |
| 0.1 | 0.3 | GO:0045759 | negative regulation of action potential(GO:0045759) |
| 0.1 | 2.0 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.1 | 0.3 | GO:0097205 | glomerular filtration(GO:0003094) renal filtration(GO:0097205) |
| 0.1 | 0.4 | GO:0090043 | tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043) |
| 0.1 | 0.2 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.1 | 0.5 | GO:0051610 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 1.0 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 1.0 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.5 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.0 | 1.5 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 1.1 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 0.2 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.0 | 0.4 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.0 | 0.5 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.0 | 0.3 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.0 | 0.8 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.0 | 0.7 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 0.2 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.0 | 0.2 | GO:0019482 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.0 | 0.7 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.0 | 0.3 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.0 | 0.4 | GO:0042723 | thiamine-containing compound metabolic process(GO:0042723) |
| 0.0 | 0.2 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.0 | 0.1 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.0 | 0.2 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.0 | 0.5 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.0 | 1.6 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.7 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.0 | 0.4 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.0 | 0.3 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 0.0 | 0.6 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.3 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 2.6 | GO:0030195 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 0.3 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.0 | 0.3 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.0 | 0.1 | GO:0072223 | metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) negative regulation of metanephric glomerulus development(GO:0072299) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) |
| 0.0 | 0.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.0 | 0.5 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 0.4 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.1 | GO:0052405 | negative regulation by host of symbiont molecular function(GO:0052405) |
| 0.0 | 0.1 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.0 | 4.1 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
| 0.0 | 0.5 | GO:0006293 | nucleotide-excision repair, preincision complex stabilization(GO:0006293) |
| 0.0 | 0.6 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.0 | 0.8 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.2 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.0 | 0.2 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
| 0.0 | 0.1 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.0 | 0.1 | GO:0035607 | vacuolar phosphate transport(GO:0007037) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) negative regulation of fibroblast growth factor production(GO:0090272) positive regulation of mitotic cell cycle DNA replication(GO:1903465) regulation of parathyroid hormone secretion(GO:2000828) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.0 | 0.4 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.0 | 0.3 | GO:0046661 | male sex differentiation(GO:0046661) |
| 0.0 | 1.0 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 1.0 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.1 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.0 | 0.2 | GO:0003352 | regulation of cilium movement(GO:0003352) |
| 0.0 | 1.6 | GO:0001510 | RNA methylation(GO:0001510) |
| 0.0 | 0.2 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.0 | 0.1 | GO:0048075 | positive regulation of eye pigmentation(GO:0048075) |
| 0.0 | 0.2 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.0 | 0.7 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.3 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 0.0 | 0.1 | GO:0060038 | cardiac muscle cell proliferation(GO:0060038) |
| 0.0 | 0.1 | GO:0015791 | polyol transport(GO:0015791) |
| 0.0 | 0.4 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 0.2 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 1.8 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.0 | 0.1 | GO:0006154 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 0.0 | 0.2 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.1 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.0 | 0.2 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.2 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.0 | 0.3 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.0 | 1.0 | GO:0035306 | positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307) |
| 0.0 | 2.6 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.0 | 0.2 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.4 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.0 | GO:0060028 | convergent extension involved in axis elongation(GO:0060028) |
| 0.0 | 0.1 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.0 | 0.2 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.0 | 1.9 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.2 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.0 | 0.1 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.0 | 0.1 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.0 | 0.0 | GO:0070944 | neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) |
| 0.0 | 0.1 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.0 | 0.2 | GO:0090181 | regulation of steroid metabolic process(GO:0019218) regulation of cholesterol biosynthetic process(GO:0045540) regulation of steroid biosynthetic process(GO:0050810) regulation of cholesterol metabolic process(GO:0090181) regulation of alcohol biosynthetic process(GO:1902930) |
| 0.0 | 0.1 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.0 | 0.4 | GO:2000179 | positive regulation of neural precursor cell proliferation(GO:2000179) |
| 0.0 | 1.3 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.0 | 0.3 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.1 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 0.1 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.0 | 0.1 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 1.2 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.0 | 0.1 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403) |
| 0.0 | 0.8 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.0 | 1.2 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.0 | 0.6 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 1.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0007017 | microtubule-based process(GO:0007017) |
| 0.0 | 0.0 | GO:0048859 | ganglion mother cell fate determination(GO:0007402) formation of anatomical boundary(GO:0048859) stem cell fate determination(GO:0048867) |
| 0.0 | 0.3 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.4 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
| 0.0 | 0.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.8 | GO:0046620 | regulation of organ growth(GO:0046620) |
| 0.0 | 0.3 | GO:0001947 | heart looping(GO:0001947) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.8 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
| 1.0 | 5.2 | GO:0098536 | deuterosome(GO:0098536) |
| 0.8 | 4.1 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.7 | 2.2 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 0.7 | 5.6 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.6 | 2.5 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 0.6 | 2.2 | GO:0036156 | inner dynein arm(GO:0036156) |
| 0.4 | 2.9 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.4 | 4.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.3 | 2.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 3.2 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.3 | 2.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.3 | 0.9 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.3 | 10.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.3 | 0.8 | GO:0030849 | autosome(GO:0030849) |
| 0.3 | 4.7 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 2.1 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.2 | 7.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.2 | 1.4 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.2 | 1.2 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.2 | 3.4 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.2 | 9.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 8.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 1.1 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.1 | 6.8 | GO:0030286 | dynein complex(GO:0030286) |
| 0.1 | 0.5 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.1 | 1.4 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 1.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 1.1 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 11.6 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 3.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 4.5 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 0.5 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 0.7 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.1 | 0.3 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 0.3 | GO:0032449 | CBM complex(GO:0032449) |
| 0.1 | 0.8 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 2.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 6.8 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 0.4 | GO:0072589 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 3.7 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.1 | 0.5 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 3.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 0.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 6.7 | GO:0031514 | motile cilium(GO:0031514) |
| 0.1 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.3 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.7 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 0.1 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 1.1 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 3.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 0.8 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 0.4 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.0 | 0.9 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.0 | 0.1 | GO:0031213 | RSF complex(GO:0031213) |
| 0.0 | 0.1 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.0 | 2.3 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.2 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.0 | 2.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 0.2 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.9 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 0.2 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.1 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.0 | 2.6 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 0.4 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 6.2 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 0.3 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.0 | 0.1 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 0.0 | 0.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 0.2 | GO:0016012 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.5 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.1 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 0.5 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.4 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.1 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 0.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.3 | GO:0043186 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.5 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.4 | GO:0005921 | gap junction(GO:0005921) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 6.6 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.7 | 2.2 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.6 | 2.5 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 0.6 | 2.9 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.6 | 4.4 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.4 | 3.2 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.4 | 3.2 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.3 | 1.7 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) |
| 0.3 | 2.7 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.3 | 0.9 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.3 | 10.1 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.3 | 2.8 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.3 | 1.0 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.2 | 2.1 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.2 | 1.3 | GO:0047756 | chondroitin 4-sulfotransferase activity(GO:0047756) |
| 0.2 | 0.4 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
| 0.2 | 4.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 0.5 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.2 | 1.2 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.2 | 1.0 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.2 | 0.6 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.2 | 1.4 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.1 | 1.8 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.1 | 0.8 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.1 | 0.7 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.1 | 0.5 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.1 | 1.0 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.1 | 0.7 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.8 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.1 | 0.4 | GO:0070513 | death domain binding(GO:0070513) |
| 0.1 | 1.7 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 1.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 1.0 | GO:0032405 | MutLalpha complex binding(GO:0032405) |
| 0.1 | 0.3 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.1 | 1.8 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 0.6 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.1 | 0.9 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.1 | 1.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 0.3 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.1 | 0.6 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.1 | 3.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 0.2 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.1 | 1.1 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 0.7 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.1 | 4.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.1 | GO:0004518 | nuclease activity(GO:0004518) |
| 0.1 | 0.6 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 0.6 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.1 | 1.3 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.1 | 0.3 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 0.1 | 0.6 | GO:0015252 | hydrogen ion channel activity(GO:0015252) |
| 0.1 | 0.4 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.1 | 3.1 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 0.3 | GO:0052846 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.1 | 3.0 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.1 | 0.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.1 | 2.9 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 0.3 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.1 | 2.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.3 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.0 | 1.1 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 1.7 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 0.9 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 1.3 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.0 | 1.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 2.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.0 | 1.2 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.0 | 1.1 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 0.1 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.0 | 2.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 1.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.2 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.0 | 1.2 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 1.0 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.2 | GO:0004096 | catalase activity(GO:0004096) |
| 0.0 | 1.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.2 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.0 | 0.2 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.0 | 1.2 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.3 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 0.2 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.0 | 0.4 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.1 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.0 | 0.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.1 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.3 | GO:0005072 | transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) |
| 0.0 | 1.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.4 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.4 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.0 | 0.1 | GO:0032296 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.0 | 0.4 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.1 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.3 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 0.1 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.0 | 0.1 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.0 | 0.6 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.2 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.6 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.0 | 0.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.8 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.0 | 0.5 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.2 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.4 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.0 | 0.7 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 4.5 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.6 | GO:0070717 | poly-purine tract binding(GO:0070717) |
| 0.0 | 0.1 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.0 | 0.3 | GO:0070742 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.1 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.2 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.1 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.0 | 0.4 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.5 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.4 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.1 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.4 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.1 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 2.0 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 14.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 8.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 3.0 | PID MYC PATHWAY | C-MYC pathway |
| 0.1 | 4.3 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 2.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.4 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.4 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 1.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.4 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 1.7 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 1.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.4 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.6 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.2 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.2 | 11.2 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.2 | 24.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 1.4 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.1 | 3.2 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.1 | 2.1 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 2.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 1.4 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 1.9 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 2.1 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.2 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 4.4 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 0.7 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.4 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 3.7 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.3 | REACTOME ORC1 REMOVAL FROM CHROMATIN | Genes involved in Orc1 removal from chromatin |
| 0.0 | 1.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.5 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.1 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.0 | 0.5 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.1 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 0.1 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 0.2 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 1.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.5 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.6 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.3 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 0.9 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.3 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.3 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.6 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.3 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 0.1 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.2 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.1 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |