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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MYOD1

Z-value: 0.85

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Transcription factors associated with MYOD1

Gene Symbol Gene ID Gene Info
ENSG00000129152.3 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYOD1hg19_v2_chr11_+_17741111_17741124-0.019.5e-01Click!

Activity profile of MYOD1 motif

Sorted Z-values of MYOD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_67427389 5.49 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr10_-_13043697 3.75 ENST00000378825.3
coiled-coil domain containing 3
chr3_-_50383096 3.37 ENST00000442887.1
ENST00000360165.3
zinc finger, MYND-type containing 10
chr16_+_67465016 2.98 ENST00000326152.5
hydroxysteroid (11-beta) dehydrogenase 2
chr11_+_27062860 2.97 ENST00000528583.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr17_+_68165657 2.49 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr2_+_85981008 2.44 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr7_-_120497178 2.17 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr11_+_86511549 1.99 ENST00000533902.2
protease, serine, 23
chrX_-_99665262 1.97 ENST00000373034.4
ENST00000255531.7
protocadherin 19
chr13_-_26625169 1.90 ENST00000319420.3
shisa family member 2
chr5_-_150603679 1.85 ENST00000355417.2
coiled-coil domain containing 69
chr12_+_50355647 1.83 ENST00000293599.6
aquaporin 5
chr3_+_111393659 1.77 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr2_-_154335300 1.77 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr6_-_24911195 1.77 ENST00000259698.4
family with sequence similarity 65, member B
chr16_-_84273304 1.77 ENST00000308251.4
ENST00000568181.1
potassium voltage-gated channel, subfamily G, member 4
chr17_-_46035187 1.74 ENST00000300557.2
proline rich 15-like
chr11_+_27062272 1.70 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_+_165675269 1.68 ENST00000507311.1
RP11-294O2.2
chr11_+_27062502 1.60 ENST00000263182.3
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_162351503 1.56 ENST00000458626.2
chromosome 1 open reading frame 226
chr19_-_7990991 1.50 ENST00000318978.4
cortexin 1
chr7_-_73184588 1.46 ENST00000395145.2
claudin 3
chr22_-_36013368 1.42 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr10_+_94608245 1.38 ENST00000443748.2
ENST00000260762.6
exocyst complex component 6
chr1_+_87794150 1.30 ENST00000370544.5
LIM domain only 4
chr6_+_17281573 1.29 ENST00000379052.5
RNA binding motif protein 24
chr2_-_220435963 1.24 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
obscurin-like 1
chr1_+_60280458 1.21 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr12_+_56473628 1.20 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr9_+_36136700 1.17 ENST00000396613.3
ENST00000377959.1
ENST00000377960.4
GLI pathogenesis-related 2
chr1_+_89990431 1.17 ENST00000330947.2
ENST00000358200.4
leucine rich repeat containing 8 family, member B
chr4_-_23891693 1.16 ENST00000264867.2
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr5_-_159739532 1.16 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
cyclin J-like
chr9_-_80263220 1.15 ENST00000341700.6
guanine nucleotide binding protein (G protein), alpha 14
chr14_-_100625932 1.14 ENST00000553834.1
delta(4)-desaturase, sphingolipid 2
chr3_-_66024213 1.14 ENST00000483466.1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr11_+_45918092 1.11 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr2_+_223289208 1.08 ENST00000321276.7
sphingosine-1-phosphate phosphatase 2
chr7_+_73442487 1.07 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
elastin
chr5_+_131630117 1.04 ENST00000200652.3
solute carrier family 22 (organic cation/zwitterion transporter), member 4
chr11_-_33891362 1.03 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr1_-_223537475 1.01 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
sushi domain containing 4
chr2_+_121103706 1.00 ENST00000295228.3
inhibin, beta B
chr1_-_154928562 1.00 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr11_+_6411670 0.98 ENST00000530395.1
ENST00000527275.1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr16_+_83932684 0.98 ENST00000262430.4
malonyl-CoA decarboxylase
chr1_-_226129083 0.96 ENST00000420304.2
left-right determination factor 2
chr8_-_121824374 0.96 ENST00000517992.1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr20_+_58179582 0.95 ENST00000371015.1
ENST00000395639.4
phosphatase and actin regulator 3
chr11_+_6411636 0.95 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
sphingomyelin phosphodiesterase 1, acid lysosomal
chr15_-_42186248 0.94 ENST00000320955.6
spectrin, beta, non-erythrocytic 5
chr1_-_40367668 0.94 ENST00000397332.2
ENST00000429311.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr1_-_226129189 0.93 ENST00000366820.5
left-right determination factor 2
chr5_+_50678921 0.91 ENST00000230658.7
ISL LIM homeobox 1
chr1_-_223537401 0.91 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
sushi domain containing 4
chr21_-_34185944 0.90 ENST00000479548.1
chromosome 21 open reading frame 62
chr7_+_73442422 0.89 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
elastin
chr17_-_72968809 0.89 ENST00000530857.1
ENST00000425042.2
HID1 domain containing
chr11_-_108464465 0.88 ENST00000525344.1
exophilin 5
chr5_+_169532896 0.87 ENST00000306268.6
ENST00000449804.2
forkhead box I1
chr6_+_149068464 0.86 ENST00000367463.4
uronyl-2-sulfotransferase
chr7_+_107301065 0.86 ENST00000265715.3
solute carrier family 26 (anion exchanger), member 4
chr4_+_129732467 0.86 ENST00000413543.2
jade family PHD finger 1
chr1_-_57285038 0.84 ENST00000343433.6
chromosome 1 open reading frame 168
chr17_-_7216939 0.82 ENST00000573684.1
G protein pathway suppressor 2
chr1_-_75139397 0.82 ENST00000326665.5
chromosome 1 open reading frame 173
chr6_-_33714752 0.81 ENST00000451316.1
inositol hexakisphosphate kinase 3
chr11_+_10476851 0.81 ENST00000396553.2
adenosine monophosphate deaminase 3
chr1_+_3614591 0.80 ENST00000378290.4
tumor protein p73
chr12_+_108525517 0.79 ENST00000332082.4
WSC domain containing 2
chr17_+_76165213 0.79 ENST00000590201.1
synaptogyrin 2
chr11_+_86511569 0.78 ENST00000441050.1
protease, serine, 23
chr12_+_122150646 0.77 ENST00000449592.2
transmembrane protein 120B
chr7_+_73442102 0.76 ENST00000445912.1
ENST00000252034.7
elastin
chr11_-_108464321 0.76 ENST00000265843.4
exophilin 5
chr2_+_95537170 0.76 ENST00000295201.4
tektin 4
chr18_-_54305658 0.75 ENST00000586262.1
ENST00000217515.6
thioredoxin-like 1
chr5_+_139027877 0.73 ENST00000302517.3
CXXC finger protein 5
chr3_-_121740969 0.73 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
immunoglobulin-like domain containing receptor 1
chr19_-_47137942 0.72 ENST00000300873.4
guanine nucleotide binding protein (G protein), gamma 8
chr7_+_116660246 0.72 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
suppression of tumorigenicity 7
chr8_-_144691718 0.72 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
pyrroline-5-carboxylate reductase-like
chr8_-_29120580 0.71 ENST00000524189.1
kinesin family member 13B
chr1_+_159750720 0.69 ENST00000368109.1
ENST00000368108.3
dual specificity phosphatase 23
chr1_+_159750776 0.68 ENST00000368107.1
dual specificity phosphatase 23
chr17_+_4981535 0.68 ENST00000318833.3
ZFP3 zinc finger protein
chr5_+_102201687 0.68 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr2_+_233562015 0.67 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GRB10 interacting GYF protein 2
chr3_+_108308513 0.67 ENST00000361582.3
DAZ interacting zinc finger protein 3
chr2_+_24714729 0.67 ENST00000406961.1
ENST00000405141.1
nuclear receptor coactivator 1
chr5_+_102201722 0.66 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chr14_+_62584197 0.66 ENST00000334389.4
long intergenic non-protein coding RNA 643
chr1_-_204329013 0.65 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr1_+_61869748 0.65 ENST00000357977.5
nuclear factor I/A
chr16_+_88772866 0.64 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chrX_+_150151752 0.64 ENST00000325307.7
high mobility group box 3
chr8_-_130951940 0.62 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
family with sequence similarity 49, member B
chr11_-_2292182 0.62 ENST00000331289.4
achaete-scute family bHLH transcription factor 2
chr5_+_102201509 0.61 ENST00000348126.2
ENST00000379787.4
peptidylglycine alpha-amidating monooxygenase
chr4_+_89299885 0.61 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr7_+_73442457 0.61 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
elastin
chr17_-_43339474 0.61 ENST00000331780.4
spermatogenesis associated 32
chr2_-_220436248 0.60 ENST00000265318.4
obscurin-like 1
chr5_+_139028510 0.60 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC finger protein 5
chr17_-_43339453 0.59 ENST00000543122.1
spermatogenesis associated 32
chr14_+_22739823 0.59 ENST00000390464.2
T cell receptor alpha variable 38-1
chr14_-_24911448 0.59 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
short chain dehydrogenase/reductase family 39U, member 1
chr17_+_26369865 0.58 ENST00000582037.1
nemo-like kinase
chr7_+_150065278 0.58 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr17_+_76164639 0.58 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
synaptogyrin 2
chr8_-_17270809 0.58 ENST00000180173.5
ENST00000521857.1
myotubularin related protein 7
chr4_+_166794862 0.57 ENST00000513213.1
tolloid-like 1
chr19_+_35521572 0.57 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr11_-_73694346 0.56 ENST00000310473.3
uncoupling protein 2 (mitochondrial, proton carrier)
chr4_+_89299994 0.56 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_-_47755436 0.56 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
speckle-type POZ protein
chr6_+_133562472 0.55 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
eyes absent homolog 4 (Drosophila)
chr6_+_138483058 0.55 ENST00000251691.4
KIAA1244
chr8_+_81397876 0.54 ENST00000430430.1
zinc finger and BTB domain containing 10
chrX_-_108868390 0.53 ENST00000372101.2
KCNE1-like
chr17_-_42277203 0.53 ENST00000587097.1
ataxin 7-like 3
chr14_-_24912047 0.53 ENST00000553930.1
short chain dehydrogenase/reductase family 39U, member 1
chr3_+_32147997 0.53 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr5_+_56111361 0.53 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr1_+_36023370 0.53 ENST00000356090.4
ENST00000373243.2
neurochondrin
chr11_+_71938925 0.52 ENST00000538751.1
inositol polyphosphate phosphatase-like 1
chr18_-_53089723 0.52 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr17_+_33474826 0.52 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
unc-45 homolog B (C. elegans)
chr17_+_33474860 0.52 ENST00000394570.2
unc-45 homolog B (C. elegans)
chr15_+_97326659 0.52 ENST00000558553.1
spermatogenesis associated 8
chr11_-_88070920 0.52 ENST00000524463.1
ENST00000227266.5
cathepsin C
chr7_+_35756186 0.51 ENST00000430518.1
AC018647.3
chr1_-_167905225 0.51 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr8_+_81398444 0.51 ENST00000455036.3
ENST00000426744.2
zinc finger and BTB domain containing 10
chr16_-_31076332 0.50 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
zinc finger protein 668
chr8_-_91657740 0.50 ENST00000422900.1
transmembrane protein 64
chr3_-_65583561 0.49 ENST00000460329.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr4_+_113970772 0.49 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr9_+_136399929 0.49 ENST00000393060.1
ADAMTS-like 2
chr11_-_8954491 0.49 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
chromosome 11 open reading frame 16
chr10_-_73848531 0.49 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_16062820 0.48 ENST00000294454.5
solute carrier family 25, member 34
chrX_+_115567767 0.48 ENST00000371900.4
solute carrier family 6 (amino acid transporter), member 14
chr1_-_86043921 0.47 ENST00000535924.2
dimethylarginine dimethylaminohydrolase 1
chr8_+_67341239 0.47 ENST00000320270.2
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chrX_-_99986494 0.47 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
synaptotagmin-like 4
chr16_+_58059470 0.47 ENST00000219271.3
matrix metallopeptidase 15 (membrane-inserted)
chr1_-_185286461 0.46 ENST00000367498.3
influenza virus NS1A binding protein
chr17_+_40985407 0.46 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr5_+_102201430 0.46 ENST00000438793.3
ENST00000346918.2
peptidylglycine alpha-amidating monooxygenase
chr10_-_62149433 0.46 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_11060004 0.46 ENST00000542579.1
ENST00000399850.3
ENST00000417956.2
CUGBP, Elav-like family member 2
chr19_+_3094398 0.46 ENST00000078429.4
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr16_+_71660079 0.45 ENST00000565261.1
ENST00000268485.3
ENST00000299952.4
MARVEL domain containing 3
chr16_-_88772670 0.45 ENST00000562544.1
ring finger protein 166
chr2_+_95963052 0.45 ENST00000295225.5
Kv channel interacting protein 3, calsenilin
chr12_-_117628253 0.44 ENST00000330622.5
F-box protein 21
chr19_+_14544099 0.44 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr16_+_103816 0.44 ENST00000383018.3
ENST00000417493.1
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr9_-_128003606 0.43 ENST00000324460.6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr6_+_44184653 0.43 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
chr8_-_91657909 0.43 ENST00000418210.2
transmembrane protein 64
chr22_+_17082732 0.43 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr3_-_49851313 0.43 ENST00000333486.3
ubiquitin-like modifier activating enzyme 7
chr2_-_178417742 0.43 ENST00000408939.3
tetratricopeptide repeat domain 30B
chr16_-_12009735 0.43 ENST00000439887.2
ENST00000434724.2
G1 to S phase transition 1
chr1_-_33647267 0.43 ENST00000291416.5
tripartite motif containing 62
chr11_+_7597639 0.43 ENST00000533792.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_40839369 0.42 ENST00000372718.3
small ArfGAP2
chr2_-_227050079 0.42 ENST00000423838.1
AC068138.1
chr18_-_52989525 0.42 ENST00000457482.3
transcription factor 4
chr11_-_67275542 0.42 ENST00000531506.1
cyclin-dependent kinase 2 associated protein 2
chr8_-_72268968 0.42 ENST00000388740.3
eyes absent homolog 1 (Drosophila)
chr7_-_150675372 0.42 ENST00000262186.5
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_-_73937244 0.41 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr8_-_37594944 0.41 ENST00000330539.1
Uncharacterized protein
chr15_-_45670924 0.40 ENST00000396659.3
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr11_-_119252359 0.40 ENST00000455332.2
ubiquitin specific peptidase 2
chr17_-_71088797 0.40 ENST00000580557.1
ENST00000579732.1
ENST00000578620.1
ENST00000542342.2
ENST00000255559.3
ENST00000579018.1
solute carrier family 39, member 11
chr3_+_52454971 0.40 ENST00000465863.1
PHD finger protein 7
chr5_+_159343688 0.40 ENST00000306675.3
adrenoceptor alpha 1B
chr14_-_24551137 0.40 ENST00000396995.1
neural retina leucine zipper
chr14_-_24551195 0.40 ENST00000560550.1
neural retina leucine zipper
chr16_-_31076273 0.40 ENST00000426488.2
zinc finger protein 668
chr17_-_56032602 0.39 ENST00000577840.1
CUE domain containing 1
chr14_-_106453155 0.39 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr14_-_89021077 0.39 ENST00000556564.1
protein tyrosine phosphatase, non-receptor type 21
chr12_-_56122426 0.39 ENST00000551173.1
CD63 molecule
chr11_+_1942580 0.39 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chr16_+_23847267 0.39 ENST00000321728.7
protein kinase C, beta
chr2_-_37899323 0.39 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr19_+_19030497 0.39 ENST00000438170.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr16_+_71660052 0.39 ENST00000567566.1
MARVEL domain containing 3
chr11_+_71238313 0.39 ENST00000398536.4
keratin associated protein 5-7
chr16_-_88772761 0.38 ENST00000567844.1
ENST00000312838.4
ring finger protein 166
chr19_+_19030478 0.38 ENST00000247003.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr19_+_16771936 0.38 ENST00000187762.2
ENST00000599479.1
transmembrane protein 38A
chr11_-_117698765 0.38 ENST00000532119.1
FXYD domain containing ion transport regulator 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MYOD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.6 2.4 GO:0018032 protein amidation(GO:0018032)
0.6 6.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 1.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.4 1.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 1.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.0 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.3 0.9 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913)
0.3 0.9 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.3 0.8 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.3 1.9 GO:0023021 termination of signal transduction(GO:0023021)
0.2 0.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 1.0 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 3.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.7 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 0.6 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.4 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 0.8 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.2 1.0 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.2 3.0 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.2 0.5 GO:0036309 protein localization to M-band(GO:0036309)
0.2 1.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 0.9 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 0.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.9 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.4 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.8 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.5 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 2.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.7 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.6 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.7 GO:0019236 response to pheromone(GO:0019236)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.6 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 1.3 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 3.2 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.5 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.9 GO:0015705 iodide transport(GO:0015705)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.9 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 1.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.9 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 1.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.9 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.1 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1 2.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.5 GO:0060482 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.2 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.6 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 5.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.3 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.6 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0061209 cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.0 0.3 GO:0070940 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.5 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 3.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.6 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 2.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.6 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.4 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.7 GO:0070997 neuron death(GO:0070997)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 1.1 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.5 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.3 GO:0006915 apoptotic process(GO:0006915)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.6 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 2.2 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.3 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.5 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.2 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.1 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.6 GO:0097427 microtubule bundle(GO:0097427)
0.4 1.3 GO:0005667 transcription factor complex(GO:0005667)
0.3 3.3 GO:0071953 elastic fiber(GO:0071953)
0.3 1.8 GO:1990393 3M complex(GO:1990393)
0.2 0.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.5 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 2.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.9 GO:0042599 lamellar body(GO:0042599)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 2.1 GO:0051233 spindle midzone(GO:0051233)
0.1 3.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 0.8 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.0 3.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.6 2.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.3 0.9 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.3 1.0 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.2 0.7 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 0.8 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.2 0.7 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 0.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 2.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 2.9 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.6 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 1.8 GO:0015250 water channel activity(GO:0015250)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.3 GO:0070984 SET domain binding(GO:0070984)
0.1 1.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.6 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 2.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 3.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.5 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0 0.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 2.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 2.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.7 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 3.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0019237 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID FGF PATHWAY FGF signaling pathway
0.0 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.0 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 5.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane