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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for MZF1

Z-value: 0.72

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Transcription factors associated with MZF1

Gene Symbol Gene ID Gene Info
MZF1
ENSG00000099326.4 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MZF1hg19_v2_chr19_-_59084647_59084721-0.222.4e-01Click!

Activity profile of MZF1 motif

Sorted Z-values of MZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51472823 2.33 ENST00000310157.2
KLK6
kallikrein-related peptidase 6
chr1_-_150208320 1.79 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_-_32157947 1.27 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr1_-_205419053 1.26 ENST00000367154.1
LEMD1
LEM domain containing 1
chr17_+_39969183 1.14 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr19_+_35645817 1.10 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr19_-_49015050 1.09 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr19_+_35645618 1.07 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr2_-_216300784 1.03 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr5_-_127873659 1.02 ENST00000262464.4
FBN2
fibrillin 2
chr14_+_24867992 0.98 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr11_-_2160180 0.95 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_-_114664180 0.92 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr2_-_72375167 0.87 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr17_+_42634844 0.83 ENST00000315323.3
FZD2
frizzled family receptor 2
chr8_+_80523962 0.78 ENST00000518491.1
STMN2
stathmin-like 2
chr17_+_76210267 0.77 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr15_-_74501360 0.77 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr21_-_44496441 0.73 ENST00000359624.3
ENST00000352178.5
CBS
cystathionine-beta-synthase
chr18_+_56530136 0.70 ENST00000591083.1
ZNF532
zinc finger protein 532
chr10_+_31608054 0.68 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chrX_-_128657457 0.67 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr10_+_120967072 0.67 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr19_+_10381769 0.66 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr17_+_76210367 0.66 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr17_+_1959369 0.63 ENST00000576444.1
ENST00000322941.3
HIC1
hypermethylated in cancer 1
chr6_+_37137939 0.63 ENST00000373509.5
PIM1
pim-1 oncogene
chr7_-_94953878 0.63 ENST00000222381.3
PON1
paraoxonase 1
chr7_-_112579869 0.62 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr15_-_75017711 0.62 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr1_-_150208291 0.60 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr10_+_114710425 0.60 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_-_36904437 0.59 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chr9_+_128509624 0.58 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr12_+_4382917 0.58 ENST00000261254.3
CCND2
cyclin D2
chr7_+_143079000 0.57 ENST00000392910.2
ZYX
zyxin
chr9_+_17134980 0.57 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr1_-_244013384 0.56 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr18_-_6414884 0.55 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr6_-_42419649 0.55 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr15_-_71055769 0.55 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chrX_+_136648297 0.54 ENST00000287538.5
ZIC3
Zic family member 3
chr2_-_26205340 0.54 ENST00000264712.3
KIF3C
kinesin family member 3C
chr15_+_75640068 0.53 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr18_+_19749386 0.52 ENST00000269216.3
GATA6
GATA binding protein 6
chr1_-_150208363 0.52 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr8_+_86376081 0.52 ENST00000285379.5
CA2
carbonic anhydrase II
chr11_+_47279504 0.51 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr7_-_143059845 0.51 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr12_-_48152428 0.50 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr7_-_19813192 0.50 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr13_-_36050819 0.50 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr4_-_57547870 0.50 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr2_+_45168875 0.49 ENST00000260653.3
SIX3
SIX homeobox 3
chr14_+_75745477 0.48 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_+_52776228 0.48 ENST00000256759.3
FST
follistatin
chr7_+_77167376 0.48 ENST00000435495.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr19_-_14201507 0.47 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr19_-_41859814 0.47 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr10_-_75401500 0.47 ENST00000359322.4
MYOZ1
myozenin 1
chr7_-_28220354 0.46 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr1_+_32084794 0.46 ENST00000373705.1
HCRTR1
hypocretin (orexin) receptor 1
chr12_+_49717081 0.46 ENST00000547807.1
ENST00000551567.1
TROAP
trophinin associated protein
chr7_-_94285402 0.46 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr22_-_37403839 0.46 ENST00000402860.3
ENST00000381821.1
TEX33
testis expressed 33
chr4_+_37892682 0.46 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr7_-_94285511 0.45 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr5_+_52776449 0.45 ENST00000396947.3
FST
follistatin
chr22_-_37403858 0.45 ENST00000405091.2
TEX33
testis expressed 33
chr7_-_94285472 0.45 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr11_-_123525289 0.45 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr12_+_22778291 0.45 ENST00000545979.1
ETNK1
ethanolamine kinase 1
chr20_-_42816206 0.44 ENST00000372980.3
JPH2
junctophilin 2
chr1_+_66999799 0.44 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr11_-_7985193 0.44 ENST00000328600.2
NLRP10
NLR family, pyrin domain containing 10
chr1_+_66999268 0.44 ENST00000371039.1
ENST00000424320.1
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chrX_-_48328631 0.44 ENST00000429543.1
ENST00000317669.5
SLC38A5
solute carrier family 38, member 5
chr11_-_115375107 0.44 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr2_+_30454390 0.43 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH
limb bud and heart development
chr3_+_111393501 0.43 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr12_+_49717019 0.43 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr12_-_48152853 0.42 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr20_+_44035847 0.42 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr7_-_143059780 0.42 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr2_+_210636697 0.42 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)
chr15_+_89346699 0.42 ENST00000558207.1
ACAN
aggrecan
chr14_-_76447336 0.42 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr1_-_235667716 0.42 ENST00000313984.3
ENST00000366600.3
B3GALNT2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr2_+_48541776 0.41 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr1_-_93426998 0.41 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr12_-_48152611 0.41 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr14_-_69445968 0.41 ENST00000438964.2
ACTN1
actinin, alpha 1
chr1_-_221915418 0.41 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr3_+_63428752 0.40 ENST00000295894.5
SYNPR
synaptoporin
chr2_-_163695128 0.40 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr3_+_63428982 0.40 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr5_+_66254698 0.40 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr10_+_114710516 0.40 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr14_+_95027772 0.39 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr1_-_24239844 0.39 ENST00000374472.4
CNR2
cannabinoid receptor 2 (macrophage)
chr17_-_76921459 0.39 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr14_-_36277857 0.38 ENST00000553892.1
ENST00000382366.3
RALGAPA1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr2_-_161056762 0.38 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr3_+_9975497 0.38 ENST00000397170.3
ENST00000383811.3
ENST00000452070.1
ENST00000326434.5
CRELD1
cysteine-rich with EGF-like domains 1
chr2_-_234763147 0.38 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP
Holliday junction recognition protein
chr12_-_22094336 0.38 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr19_-_54872556 0.37 ENST00000444687.1
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr12_-_57882577 0.37 ENST00000393797.2
ARHGAP9
Rho GTPase activating protein 9
chr16_-_30393752 0.37 ENST00000566517.1
ENST00000605106.1
SEPT1
SEPT1
septin 1
Uncharacterized protein
chr7_+_97361218 0.37 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr12_-_49259643 0.36 ENST00000309739.5
RND1
Rho family GTPase 1
chr1_+_37940153 0.36 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr5_+_82767284 0.36 ENST00000265077.3
VCAN
versican
chr7_+_94285637 0.36 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr3_-_123168551 0.36 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr14_-_69445793 0.36 ENST00000538545.2
ENST00000394419.4
ACTN1
actinin, alpha 1
chr1_-_150208412 0.36 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_47975417 0.36 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr17_-_42031300 0.36 ENST00000592796.1
PYY
peptide YY
chr19_+_926000 0.35 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr4_+_169552748 0.35 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr2_+_27193480 0.35 ENST00000233121.2
ENST00000405074.3
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr1_-_154943212 0.35 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr11_-_19262486 0.35 ENST00000250024.4
E2F8
E2F transcription factor 8
chr5_-_114938090 0.35 ENST00000427199.2
TICAM2
toll-like receptor adaptor molecule 2
chr6_+_106546808 0.34 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr2_-_161056802 0.34 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr12_-_49365501 0.34 ENST00000403957.1
ENST00000301061.4
WNT10B
wingless-type MMTV integration site family, member 10B
chr19_-_40724246 0.34 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr5_+_115177178 0.34 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr12_+_56137064 0.33 ENST00000257868.5
ENST00000546799.1
GDF11
growth differentiation factor 11
chr16_+_88872176 0.33 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr19_-_38916802 0.33 ENST00000587738.1
RASGRP4
RAS guanyl releasing protein 4
chr17_+_29421987 0.33 ENST00000431387.4
NF1
neurofibromin 1
chr17_-_74497432 0.33 ENST00000590288.1
ENST00000313080.4
ENST00000592123.1
ENST00000591255.1
ENST00000585989.1
ENST00000591697.1
ENST00000389760.4
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr6_-_32119877 0.32 ENST00000375152.2
PRRT1
proline-rich transmembrane protein 1
chr20_+_306177 0.32 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr20_+_35201857 0.32 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr16_-_79634595 0.32 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr12_-_52604607 0.32 ENST00000551894.1
ENST00000553017.1
C12orf80
chromosome 12 open reading frame 80
chr17_+_65373531 0.32 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_+_143078652 0.32 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr14_-_69446034 0.32 ENST00000193403.6
ACTN1
actinin, alpha 1
chr5_-_115177247 0.32 ENST00000500945.2
ATG12
autophagy related 12
chr19_-_42573650 0.32 ENST00000593562.1
GRIK5
glutamate receptor, ionotropic, kainate 5
chr10_+_50822480 0.31 ENST00000455728.2
CHAT
choline O-acetyltransferase
chr6_-_32119676 0.31 ENST00000211413.5
PRRT1
proline-rich transmembrane protein 1
chr8_+_22022800 0.31 ENST00000397814.3
BMP1
bone morphogenetic protein 1
chr18_-_658244 0.31 ENST00000585033.1
ENST00000323813.3
C18orf56
chromosome 18 open reading frame 56
chr8_-_95907423 0.31 ENST00000396133.3
ENST00000308108.4
CCNE2
cyclin E2
chr12_-_57871853 0.31 ENST00000549602.1
ENST00000430041.2
ARHGAP9
Rho GTPase activating protein 9
chr19_+_34287174 0.31 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr8_-_70747205 0.31 ENST00000260126.4
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr5_+_133861790 0.31 ENST00000395003.1
PHF15
jade family PHD finger 2
chr12_-_4488872 0.31 ENST00000237837.1
FGF23
fibroblast growth factor 23
chr5_-_115177496 0.31 ENST00000274459.4
ENST00000509910.1
ATG12
autophagy related 12
chr20_+_34742650 0.30 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_-_154943002 0.30 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr14_+_21538517 0.30 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr20_+_306221 0.30 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr2_+_177025619 0.30 ENST00000410016.1
HOXD3
homeobox D3
chr1_+_17531614 0.30 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr10_+_99473455 0.29 ENST00000285605.6
MARVELD1
MARVEL domain containing 1
chr6_-_110500905 0.29 ENST00000392587.2
WASF1
WAS protein family, member 1
chr9_+_34653861 0.29 ENST00000556792.1
ENST00000318041.9
ENST00000378817.4
IL11RA
interleukin 11 receptor, alpha
chr10_-_103603523 0.29 ENST00000370046.1
KCNIP2
Kv channel interacting protein 2
chr14_+_75746340 0.29 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr17_-_58469687 0.29 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr17_-_58469591 0.29 ENST00000589335.1
USP32
ubiquitin specific peptidase 32
chr18_-_35065710 0.29 ENST00000589229.1
ENST00000587819.1
CELF4
CUGBP, Elav-like family member 4
chr11_+_46722368 0.28 ENST00000311764.2
ZNF408
zinc finger protein 408
chr6_+_32121908 0.28 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr16_+_6069586 0.28 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_55647057 0.28 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr12_+_56915713 0.28 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr8_+_27632083 0.28 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr1_-_150208498 0.28 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_19754404 0.28 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chr8_+_27632047 0.28 ENST00000397418.2
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr11_+_86748998 0.28 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chr15_-_48937982 0.28 ENST00000316623.5
FBN1
fibrillin 1
chr1_+_43766642 0.28 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr4_-_165305086 0.28 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr15_-_70388599 0.27 ENST00000560996.1
ENST00000558201.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr17_-_39140549 0.27 ENST00000377755.4
KRT40
keratin 40
chr6_+_32121789 0.27 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr9_+_4985016 0.27 ENST00000539801.1
JAK2
Janus kinase 2
chrX_-_110039038 0.27 ENST00000372042.1
ENST00000482160.1
ENST00000444321.2
ENST00000218054.4
CHRDL1
chordin-like 1
chr19_+_34287751 0.27 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr2_-_219925189 0.27 ENST00000295731.6
IHH
indian hedgehog
chr11_-_35547151 0.27 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr2_-_61765315 0.27 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_-_10251603 0.27 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr12_+_56915776 0.26 ENST00000550726.1
ENST00000542360.1
RBMS2
RNA binding motif, single stranded interacting protein 2
chr10_-_89623194 0.26 ENST00000445946.3
KLLN
killin, p53-regulated DNA replication inhibitor
chr11_-_74442430 0.26 ENST00000376332.3
CHRDL2
chordin-like 2
chr14_+_21538429 0.26 ENST00000298694.4
ENST00000555038.1
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr1_+_150337100 0.26 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chrX_-_110039286 0.26 ENST00000434224.1
CHRDL1
chordin-like 1
chr6_-_42418999 0.26 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.4 1.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 1.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.3 1.3 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3 0.9 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 0.7 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.2 0.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 1.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.6 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.2 0.6 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.2 0.9 GO:1902617 response to fluoride(GO:1902617)
0.2 0.9 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2 1.0 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 0.5 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.7 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 0.5 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.5 GO:1900126 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.4 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 1.7 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.5 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 2.6 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.5 GO:0048749 compound eye development(GO:0048749)
0.1 1.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.3 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.8 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.6 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.6 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.4 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 1.0 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.7 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.8 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 4.0 GO:0043486 histone exchange(GO:0043486)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.4 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.0 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 1.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.2 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 0.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.5 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.2 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1 0.1 GO:0021764 amygdala development(GO:0021764)
0.1 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.5 GO:0097118 gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0003285 septum secundum development(GO:0003285)
0.0 0.1 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.1 GO:1990927 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0061312 BMP signaling pathway involved in heart development(GO:0061312)
0.0 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.3 GO:0070120 brainstem development(GO:0003360) ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.2 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.2 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.1 GO:0061325 cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.2 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.0 0.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.4 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.7 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.6 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077) negative regulation of B cell differentiation(GO:0045578)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.0 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.4 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.0 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.0 0.0 GO:0098907 regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.3 GO:0007614 short-term memory(GO:0007614)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0098743 cell aggregation(GO:0098743)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 1.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 3.6 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0036029 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.9 GO:0035976 AP1 complex(GO:0035976)
0.1 0.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.6 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 1.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.8 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0005921 gap junction(GO:0005921)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0098809 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2 0.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 0.6 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.7 GO:0016499 orexin receptor activity(GO:0016499)
0.2 0.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.8 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1 1.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.9 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.5 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 0.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.5 GO:0042835 BRE binding(GO:0042835)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.3 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.7 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.2 GO:0004132 dCMP deaminase activity(GO:0004132)
0.1 1.0 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.9 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 3.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 1.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.1 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.0 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein antigen binding(GO:1990405)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 3.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 3.3 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules