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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NFATC1

Z-value: 1.07

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Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
NFATC1
ENSG00000131196.13 nuclear factor of activated T cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC1hg19_v2_chr18_+_77155856_771559390.523.4e-03Click!

Activity profile of NFATC1 motif

Sorted Z-values of NFATC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_16085340 10.70 ENST00000508167.1
PROM1
prominin 1
chr4_-_16085314 10.67 ENST00000510224.1
PROM1
prominin 1
chr6_+_32407619 9.46 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr4_-_100356291 7.37 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr14_-_92413727 6.19 ENST00000267620.10
FBLN5
fibulin 5
chr1_-_161337662 5.70 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr6_-_32920794 5.14 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr5_-_54468974 4.73 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr1_-_36906474 4.31 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr4_-_38806404 4.25 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr14_-_92413353 4.21 ENST00000556154.1
FBLN5
fibulin 5
chr9_+_124922171 4.10 ENST00000373764.3
ENST00000536616.1
MORN5
MORN repeat containing 5
chr1_+_151682909 3.83 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr10_+_94590910 3.83 ENST00000371547.4
EXOC6
exocyst complex component 6
chrX_-_99665262 3.75 ENST00000373034.4
ENST00000255531.7
PCDH19
protocadherin 19
chr5_+_140261703 3.72 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr1_+_36549676 3.57 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr10_+_115511213 3.52 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr1_+_79115503 3.43 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr7_+_6793740 3.36 ENST00000403107.1
ENST00000404077.1
ENST00000435395.1
ENST00000418406.1
RSPH10B2
radial spoke head 10 homolog B2 (Chlamydomonas)
chr7_-_6010263 3.32 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr1_+_61548374 3.17 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
NFIA
nuclear factor I/A
chr5_+_140207536 3.14 ENST00000529310.1
ENST00000527624.1
PCDHA6
protocadherin alpha 6
chr2_-_159237472 3.10 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr4_-_70518941 2.75 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr3_+_14444063 2.51 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr1_+_61547405 2.45 ENST00000371189.4
NFIA
nuclear factor I/A
chr4_+_41614909 2.35 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr1_+_61548225 2.25 ENST00000371187.3
NFIA
nuclear factor I/A
chr8_+_81397876 2.23 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr1_+_46640750 2.20 ENST00000372003.1
TSPAN1
tetraspanin 1
chr9_-_20622478 2.00 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_+_159443090 1.99 ENST00000343542.5
ENST00000470033.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr11_+_36616044 1.99 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chr18_-_53177984 1.98 ENST00000543082.1
TCF4
transcription factor 4
chr12_-_91573132 1.94 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr4_-_168155417 1.92 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr14_-_89883412 1.85 ENST00000557258.1
FOXN3
forkhead box N3
chr12_+_93771659 1.78 ENST00000337179.5
ENST00000415493.2
NUDT4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr6_-_134495992 1.75 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chrX_+_36254051 1.75 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr1_-_151798546 1.72 ENST00000356728.6
RORC
RAR-related orphan receptor C
chrX_+_9431324 1.72 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr9_+_27109392 1.68 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr4_-_168155300 1.68 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_-_102401469 1.66 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr18_+_61575200 1.62 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_+_244214577 1.61 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr1_+_167298281 1.59 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr3_+_140981456 1.55 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr4_-_168155169 1.54 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_36986534 1.51 ENST00000429976.2
ENST00000301807.6
TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
chr11_-_75062829 1.49 ENST00000393505.4
ARRB1
arrestin, beta 1
chr3_+_69812877 1.48 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chrY_+_15017624 1.42 ENST00000440554.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr8_-_72268968 1.42 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr4_-_168155577 1.35 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr8_-_140715294 1.33 ENST00000303015.1
ENST00000520439.1
KCNK9
potassium channel, subfamily K, member 9
chr3_-_57530051 1.32 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
DNAH12
dynein, axonemal, heavy chain 12
chr1_+_22351977 1.32 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr1_+_235491714 1.31 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
GGPS1
geranylgeranyl diphosphate synthase 1
chr2_-_157198860 1.30 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr18_-_53257027 1.30 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr18_-_52989525 1.28 ENST00000457482.3
TCF4
transcription factor 4
chr18_+_77155856 1.24 ENST00000253506.5
ENST00000591814.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr3_+_132316081 1.23 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr18_-_53089723 1.21 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr13_-_62001982 1.20 ENST00000409186.1
PCDH20
protocadherin 20
chr6_-_119670919 1.19 ENST00000368468.3
MAN1A1
mannosidase, alpha, class 1A, member 1
chr1_+_180601139 1.15 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr10_-_1246317 1.15 ENST00000381305.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr10_-_1246300 1.13 ENST00000381310.3
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr5_-_111093759 1.11 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr16_+_30968615 1.09 ENST00000262519.8
SETD1A
SET domain containing 1A
chr9_-_215744 1.09 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr20_+_43990576 1.09 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr11_-_75062730 1.07 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr19_+_16059818 1.06 ENST00000322107.1
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr5_-_73937244 1.04 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr8_-_17555164 1.04 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr9_-_73483958 1.04 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chrX_-_84634737 1.00 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chrX_-_84634708 0.99 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr14_+_81421710 0.99 ENST00000342443.6
TSHR
thyroid stimulating hormone receptor
chr6_-_39082922 0.99 ENST00000229903.4
SAYSD1
SAYSVFN motif domain containing 1
chr12_+_122181529 0.97 ENST00000541467.1
TMEM120B
transmembrane protein 120B
chr10_+_22610124 0.96 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr12_-_59314246 0.95 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chrX_-_13835461 0.95 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr18_-_52989217 0.93 ENST00000570287.2
TCF4
transcription factor 4
chr13_+_96085847 0.92 ENST00000376873.3
CLDN10
claudin 10
chr2_+_46926326 0.91 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr1_-_111743285 0.90 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr14_+_81421921 0.89 ENST00000554263.1
ENST00000554435.1
TSHR
thyroid stimulating hormone receptor
chrX_+_105412290 0.87 ENST00000357175.2
ENST00000337685.2
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr11_-_122930121 0.87 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chrX_-_10544942 0.86 ENST00000380779.1
MID1
midline 1 (Opitz/BBB syndrome)
chr14_+_93897272 0.84 ENST00000393151.2
UNC79
unc-79 homolog (C. elegans)
chr4_-_104021009 0.83 ENST00000509245.1
ENST00000296424.4
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chrX_-_13835147 0.81 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr12_-_51422017 0.80 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chrX_+_133941218 0.78 ENST00000370784.4
ENST00000370785.3
FAM122C
family with sequence similarity 122C
chr19_+_35939154 0.76 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr17_+_32582293 0.76 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr12_+_109915179 0.75 ENST00000434735.2
UBE3B
ubiquitin protein ligase E3B
chr3_-_65583561 0.74 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr2_-_97535708 0.73 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr6_+_52051171 0.73 ENST00000340057.1
IL17A
interleukin 17A
chr11_-_122929699 0.71 ENST00000526686.1
HSPA8
heat shock 70kDa protein 8
chr15_+_59730348 0.70 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chrX_+_133941250 0.69 ENST00000445123.1
FAM122C
family with sequence similarity 122C
chr6_-_15663198 0.69 ENST00000338950.5
ENST00000511762.2
ENST00000355917.3
ENST00000344537.5
DTNBP1
dystrobrevin binding protein 1
chr17_-_35969409 0.69 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chrX_-_46759138 0.68 ENST00000377879.3
CXorf31
chromosome X open reading frame 31
chr12_+_11802753 0.68 ENST00000396373.4
ETV6
ets variant 6
chr1_-_77685084 0.66 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr9_+_22446814 0.65 ENST00000325870.2
DMRTA1
DMRT-like family A1
chr10_-_72141330 0.65 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr13_-_67804445 0.65 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chr11_+_34642656 0.65 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr5_-_135231516 0.65 ENST00000274520.1
IL9
interleukin 9
chr15_+_100347228 0.64 ENST00000559714.1
ENST00000560059.1
CTD-2054N24.2
Uncharacterized protein
chr7_-_25702669 0.64 ENST00000446840.1
AC003090.1
AC003090.1
chr13_+_73629107 0.62 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr2_+_86668464 0.62 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr22_-_19512893 0.62 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr19_+_56459198 0.61 ENST00000291971.3
ENST00000590542.1
NLRP8
NLR family, pyrin domain containing 8
chr16_-_21436459 0.60 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr11_-_2182388 0.60 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr7_-_100493744 0.60 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr8_+_86121448 0.60 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr2_-_46769694 0.58 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr15_-_43785303 0.58 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1
tumor protein p53 binding protein 1
chr5_+_49962772 0.57 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_-_72492903 0.57 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr10_+_96698406 0.56 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr7_-_156803329 0.56 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr8_-_124553437 0.56 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr9_+_35161998 0.56 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B
unc-13 homolog B (C. elegans)
chr11_+_65190245 0.55 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr10_+_104535994 0.55 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr1_+_174846570 0.55 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_91487013 0.54 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr16_-_4323015 0.54 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr14_-_35591433 0.54 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr12_+_1929783 0.54 ENST00000535041.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr1_+_150254936 0.53 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr13_-_49975632 0.53 ENST00000457041.1
ENST00000355854.4
CAB39L
calcium binding protein 39-like
chr12_-_123921256 0.53 ENST00000280571.8
RILPL2
Rab interacting lysosomal protein-like 2
chr8_+_38831683 0.53 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr5_+_38445641 0.52 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr1_+_44870866 0.52 ENST00000355387.2
ENST00000361799.2
RNF220
ring finger protein 220
chr18_+_77155942 0.52 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr12_+_1929421 0.52 ENST00000543818.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr5_+_7869217 0.51 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr4_+_146403912 0.51 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chrX_+_76709648 0.51 ENST00000439435.1
FGF16
fibroblast growth factor 16
chr3_-_182817367 0.50 ENST00000265594.4
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr2_+_178977143 0.50 ENST00000286070.5
RBM45
RNA binding motif protein 45
chr2_+_46926048 0.50 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr12_+_1929644 0.49 ENST00000299194.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr5_+_140787600 0.49 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr5_+_140729649 0.49 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr3_-_79068594 0.49 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_+_41509851 0.48 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr12_-_70093065 0.48 ENST00000553096.1
BEST3
bestrophin 3
chr9_-_35815013 0.48 ENST00000259667.5
HINT2
histidine triad nucleotide binding protein 2
chr19_+_10197463 0.48 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr14_+_51026743 0.48 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1
atlastin GTPase 1
chr8_+_7353368 0.47 ENST00000355602.2
DEFB107B
defensin, beta 107B
chr14_+_21538517 0.47 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr20_-_43589109 0.47 ENST00000372813.3
TOMM34
translocase of outer mitochondrial membrane 34
chr12_-_114843889 0.47 ENST00000405440.2
TBX5
T-box 5
chr3_-_185270383 0.46 ENST00000296252.4
LIPH
lipase, member H
chr1_+_174769006 0.46 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr11_-_129062093 0.46 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr14_-_35873856 0.46 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr4_-_11431389 0.46 ENST00000002596.5
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr16_-_30457048 0.45 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr11_-_68780824 0.45 ENST00000441623.1
ENST00000309099.6
MRGPRF
MAS-related GPR, member F
chr17_-_70588936 0.45 ENST00000453722.2
LINC00511
long intergenic non-protein coding RNA 511
chr8_+_145294015 0.45 ENST00000544576.1
MROH1
maestro heat-like repeat family member 1
chr2_-_227050079 0.45 ENST00000423838.1
AC068138.1
AC068138.1
chr8_-_7673238 0.44 ENST00000335021.2
DEFB107A
defensin, beta 107A
chr11_+_60970852 0.44 ENST00000325558.6
PGA3
pepsinogen 3, group I (pepsinogen A)
chr5_-_7869108 0.44 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FASTKD3
FAST kinase domains 3
chr10_-_65028938 0.44 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr1_+_235492300 0.43 ENST00000476121.1
ENST00000497327.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr12_+_20968608 0.43 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_+_158323755 0.43 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1E
CD1e molecule
chrX_-_24690771 0.43 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr3_+_98072698 0.42 ENST00000354924.2
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr16_-_55909255 0.42 ENST00000290567.9
CES5A
carboxylesterase 5A
chr16_-_55909272 0.42 ENST00000319165.9
CES5A
carboxylesterase 5A
chr8_-_145754428 0.41 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr17_-_39334460 0.41 ENST00000377726.2
KRTAP4-2
keratin associated protein 4-2
chr16_+_15528332 0.41 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr7_-_105319536 0.41 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr15_-_30685563 0.40 ENST00000401522.3
CHRFAM7A
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
chr14_+_58894706 0.40 ENST00000261244.5
KIAA0586
KIAA0586

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 21.4 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
3.6 14.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
2.5 7.4 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.4 4.3 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.8 10.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 1.7 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.4 1.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 9.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.4 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.3 1.6 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.3 1.8 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 3.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 0.8 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3 0.8 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 2.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.6 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.2 1.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.6 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 1.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 7.9 GO:0060074 synapse maturation(GO:0060074)
0.2 0.9 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.5 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 0.8 GO:0015692 lead ion transport(GO:0015692)
0.2 3.0 GO:0007379 segment specification(GO:0007379)
0.2 0.5 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 1.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.5 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.6 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.6 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.7 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.4 GO:0042704 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.5 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 1.2 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:2000302 regulation of synaptic vesicle priming(GO:0010807) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 2.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.9 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.7 GO:0060179 male mating behavior(GO:0060179)
0.1 0.9 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.7 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.1 0.5 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 1.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 0.4 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.3 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.1 1.0 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.5 GO:0061141 lung ciliated cell differentiation(GO:0061141) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.2 GO:2000566 positive regulation of thymocyte migration(GO:2000412) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.5 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 1.7 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.5 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.3 GO:0044849 estrous cycle(GO:0044849)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.8 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 3.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 11.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.2 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.6 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:0043132 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 1.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 1.8 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.8 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) negative regulation of cholesterol efflux(GO:0090370)
0.0 2.2 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 1.6 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0060701 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 4.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 1.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 1.1 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.6 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 2.0 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 5.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.2 GO:0032596 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.5 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0036344 platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 2.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
1.2 21.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
1.0 10.4 GO:0071953 elastic fiber(GO:0071953)
0.7 14.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 0.9 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 2.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 3.8 GO:0000145 exocyst(GO:0000145)
0.1 5.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.6 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 1.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 2.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 7.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 3.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 4.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.6 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:0030286 dynein complex(GO:0030286)
0.0 1.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.2 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.4 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.1 4.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.9 2.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.6 4.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.5 7.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.5 6.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3 22.1 GO:0042805 actinin binding(GO:0042805)
0.3 1.8 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.3 1.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 0.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 7.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 6.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.7 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 1.4 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 1.8 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.7 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.0 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 0.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 0.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 0.5 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 2.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.6 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 1.1 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 2.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.2 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.2 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 1.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 1.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 13.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.3 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.5 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 2.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 7.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 10.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 7.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.8 PID INSULIN PATHWAY Insulin Pathway
0.0 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 5.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 4.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 6.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 4.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 3.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4