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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NFATC4

Z-value: 1.09

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Transcription factors associated with NFATC4

Gene Symbol Gene ID Gene Info
NFATC4
ENSG00000100968.9 nuclear factor of activated T cells 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC4hg19_v2_chr14_+_24837226_24837547-0.422.1e-02Click!

Activity profile of NFATC4 motif

Sorted Z-values of NFATC4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_98703643 10.58 ENST00000477737.1
VWA3B
von Willebrand factor A domain containing 3B
chr14_+_96949319 6.73 ENST00000554706.1
AK7
adenylate kinase 7
chr1_-_161337662 5.39 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr11_+_101918153 4.66 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr14_+_96858433 3.97 ENST00000267584.4
AK7
adenylate kinase 7
chr1_+_111889212 3.86 ENST00000369737.4
PIFO
primary cilia formation
chr1_-_75139397 3.82 ENST00000326665.5
C1orf173
chromosome 1 open reading frame 173
chr2_-_207629997 3.65 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr2_-_207630033 3.50 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr14_+_75536335 3.17 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr14_+_75536280 3.09 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr5_+_140254884 2.85 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr4_-_100356551 2.81 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr10_-_116444371 2.74 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr9_-_80263220 2.72 ENST00000341700.6
GNA14
guanine nucleotide binding protein (G protein), alpha 14
chr16_+_57769635 2.68 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr11_-_62474803 2.44 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_-_71551652 2.44 ENST00000546561.1
TSPAN8
tetraspanin 8
chr1_-_159869912 2.39 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr2_+_27237615 2.39 ENST00000458529.1
ENST00000402218.1
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr5_-_41261540 2.37 ENST00000263413.3
C6
complement component 6
chr11_+_1942580 2.34 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr21_-_34185944 2.30 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr4_-_100356844 2.19 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr5_-_43412418 2.09 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr12_-_58329888 1.97 ENST00000546580.1
RP11-620J15.3
RP11-620J15.3
chr4_-_100356291 1.96 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_53343577 1.95 ENST00000573945.1
HLF
hepatic leukemia factor
chr22_-_39548627 1.95 ENST00000216133.5
CBX7
chromobox homolog 7
chr12_+_51318513 1.89 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr1_+_212782012 1.74 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr6_-_152639479 1.73 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr8_-_110703819 1.72 ENST00000532779.1
ENST00000534578.1
SYBU
syntabulin (syntaxin-interacting)
chr14_+_21156915 1.66 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr11_+_6866883 1.64 ENST00000299454.4
ENST00000379831.2
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chr12_-_49582978 1.59 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr8_+_94767109 1.57 ENST00000409623.3
ENST00000453906.1
ENST00000521517.1
TMEM67
transmembrane protein 67
chr11_+_36616355 1.57 ENST00000532470.2
C11orf74
chromosome 11 open reading frame 74
chr2_+_98330009 1.52 ENST00000264972.5
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr5_-_124081008 1.43 ENST00000306315.5
ZNF608
zinc finger protein 608
chr10_+_81838411 1.42 ENST00000372281.3
ENST00000372277.3
ENST00000372275.1
ENST00000372274.1
TMEM254
transmembrane protein 254
chr17_-_5026397 1.41 ENST00000250076.3
ZNF232
zinc finger protein 232
chrX_+_36254051 1.40 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr10_-_62704005 1.38 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr3_-_114035026 1.35 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr14_-_92413353 1.32 ENST00000556154.1
FBLN5
fibulin 5
chr17_-_39165366 1.24 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr7_-_105319536 1.21 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr15_-_52587945 1.20 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C
myosin VC
chr3_+_160559931 1.18 ENST00000464260.1
ENST00000295839.9
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr1_+_61869748 1.17 ENST00000357977.5
NFIA
nuclear factor I/A
chr15_-_77712477 1.15 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr14_+_32546274 1.11 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr8_-_72274095 1.11 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr8_+_86157699 1.11 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr3_+_108321623 1.10 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr4_-_100212132 1.08 ENST00000209668.2
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr16_-_54963026 1.05 ENST00000560208.1
ENST00000557792.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chrX_+_22056165 1.04 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr17_-_39280419 1.03 ENST00000394014.1
KRTAP4-12
keratin associated protein 4-12
chr2_-_242089677 1.02 ENST00000405260.1
PASK
PAS domain containing serine/threonine kinase
chr14_+_75988768 1.00 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr10_+_81838792 1.00 ENST00000372273.3
TMEM254
transmembrane protein 254
chr7_-_99679324 0.99 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr17_+_76311791 0.99 ENST00000586321.1
AC061992.2
AC061992.2
chr3_-_119379427 0.99 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr11_+_100862811 0.97 ENST00000303130.2
TMEM133
transmembrane protein 133
chr14_+_62585332 0.97 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr12_-_39734783 0.96 ENST00000552961.1
KIF21A
kinesin family member 21A
chr9_+_92219919 0.95 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr3_-_149051194 0.92 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr1_+_79115503 0.91 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr5_-_135231516 0.91 ENST00000274520.1
IL9
interleukin 9
chr4_-_107957454 0.90 ENST00000285311.3
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr8_-_57123815 0.90 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr3_+_184055240 0.90 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr14_+_58754751 0.89 ENST00000598233.1
AL132989.1
AL132989.1
chr6_+_122720681 0.88 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr14_-_89883412 0.88 ENST00000557258.1
FOXN3
forkhead box N3
chr1_+_61547894 0.85 ENST00000403491.3
NFIA
nuclear factor I/A
chr14_+_81421710 0.84 ENST00000342443.6
TSHR
thyroid stimulating hormone receptor
chr6_-_134495992 0.84 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr5_-_42811986 0.83 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr2_-_46769694 0.83 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr1_-_160231451 0.82 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr6_+_127898312 0.82 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr1_-_57045228 0.82 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr6_+_6588902 0.81 ENST00000230568.4
LY86
lymphocyte antigen 86
chr1_+_164528866 0.81 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr3_-_114790179 0.81 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_96076334 0.80 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr9_-_13165457 0.80 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr6_-_154677900 0.80 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr3_-_121740969 0.79 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr12_-_95945246 0.78 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr14_+_88852059 0.77 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr5_+_43602750 0.77 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr14_+_81421921 0.74 ENST00000554263.1
ENST00000554435.1
TSHR
thyroid stimulating hormone receptor
chr8_+_28747884 0.74 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1
homeobox containing 1
chr6_+_90272027 0.73 ENST00000522441.1
ANKRD6
ankyrin repeat domain 6
chr11_+_93063878 0.73 ENST00000298050.3
CCDC67
coiled-coil domain containing 67
chr21_-_34185989 0.73 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr11_-_47600320 0.73 ENST00000525720.1
ENST00000531067.1
ENST00000533290.1
ENST00000529499.1
ENST00000529946.1
ENST00000526005.1
ENST00000395288.2
ENST00000534239.1
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr3_+_119316721 0.72 ENST00000488919.1
ENST00000495992.1
PLA1A
phospholipase A1 member A
chr9_+_26956371 0.72 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr11_-_47600549 0.72 ENST00000430070.2
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr19_+_39759154 0.71 ENST00000331982.5
IFNL2
interferon, lambda 2
chr5_+_132009675 0.71 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr4_-_84256024 0.71 ENST00000311412.5
HPSE
heparanase
chr1_-_145470383 0.71 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr16_-_86588627 0.70 ENST00000565482.1
ENST00000564364.1
ENST00000561989.1
ENST00000543303.2
ENST00000381214.5
ENST00000360900.6
ENST00000322911.6
ENST00000546093.1
ENST00000569000.1
ENST00000562994.1
ENST00000561522.1
MTHFSD
methenyltetrahydrofolate synthetase domain containing
chrX_+_9431324 0.70 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr7_-_120498357 0.70 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr5_-_42812143 0.69 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr10_+_118350468 0.69 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr5_+_43603229 0.69 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr6_-_15586238 0.68 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr14_-_21979428 0.67 ENST00000538267.1
ENST00000298717.4
METTL3
methyltransferase like 3
chr4_+_26322185 0.67 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr12_+_3600356 0.66 ENST00000382622.3
PRMT8
protein arginine methyltransferase 8
chr4_-_1670632 0.66 ENST00000461064.1
FAM53A
family with sequence similarity 53, member A
chr12_+_109577202 0.66 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr3_+_69812877 0.65 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr11_-_46142505 0.64 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr12_-_49582593 0.64 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr12_-_90049828 0.64 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_90049878 0.64 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr11_-_62457371 0.63 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr14_+_75988851 0.63 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr17_+_79953310 0.61 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr11_-_116662593 0.61 ENST00000227665.4
APOA5
apolipoprotein A-V
chr12_-_9268707 0.61 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr2_-_101767715 0.61 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr17_+_48610074 0.59 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr3_+_119316689 0.59 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr16_+_67381263 0.58 ENST00000541146.1
ENST00000563189.1
ENST00000290940.7
LRRC36
leucine rich repeat containing 36
chr16_+_78056412 0.58 ENST00000299642.4
ENST00000575655.1
CLEC3A
C-type lectin domain family 3, member A
chr7_-_64023441 0.58 ENST00000309683.6
ZNF680
zinc finger protein 680
chr14_+_22636283 0.57 ENST00000557168.1
TRAV30
T cell receptor alpha variable 30
chrX_+_15518923 0.57 ENST00000348343.6
BMX
BMX non-receptor tyrosine kinase
chr1_-_151299842 0.57 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr6_+_140175987 0.56 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr11_-_46142615 0.56 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr10_+_97733786 0.56 ENST00000371198.2
CC2D2B
coiled-coil and C2 domain containing 2B
chr1_-_151431909 0.56 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chrX_+_76709648 0.55 ENST00000439435.1
FGF16
fibroblast growth factor 16
chr18_+_32556892 0.55 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_+_174846570 0.55 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr4_+_26322409 0.54 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_186560462 0.53 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr3_+_186560476 0.52 ENST00000320741.2
ENST00000444204.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr5_+_167718604 0.52 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr11_-_46142948 0.52 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr16_+_67381289 0.52 ENST00000435835.3
LRRC36
leucine rich repeat containing 36
chr11_+_66234216 0.52 ENST00000349459.6
ENST00000320740.7
ENST00000524466.1
ENST00000526296.1
PELI3
pellino E3 ubiquitin protein ligase family member 3
chr19_-_10697895 0.52 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chrX_-_134478012 0.51 ENST00000370766.3
ZNF75D
zinc finger protein 75D
chr5_+_149109825 0.50 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chrX_-_84634708 0.50 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr2_-_152830479 0.50 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chrX_-_65259914 0.50 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chr2_+_233562015 0.50 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2
GRB10 interacting GYF protein 2
chr12_-_89918522 0.49 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chrX_-_65259900 0.48 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr11_-_10315741 0.47 ENST00000256190.8
SBF2
SET binding factor 2
chr7_+_142364193 0.47 ENST00000390397.2
TRBV24-1
T cell receptor beta variable 24-1
chr9_+_104161123 0.47 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189
zinc finger protein 189
chr2_+_86668464 0.47 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr3_+_138340067 0.47 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr1_+_36789335 0.46 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr7_-_25702669 0.46 ENST00000446840.1
AC003090.1
AC003090.1
chr20_+_15177480 0.46 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr17_+_7792101 0.46 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr6_-_110736742 0.45 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chrX_-_84634737 0.44 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr2_-_175712270 0.44 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr9_+_91933407 0.44 ENST00000375807.3
ENST00000339901.4
SECISBP2
SECIS binding protein 2
chrY_+_20708557 0.43 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr7_-_141673573 0.43 ENST00000547270.1
TAS2R38
taste receptor, type 2, member 38
chr7_+_120628731 0.43 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr14_+_88471468 0.43 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr20_-_30310693 0.42 ENST00000307677.4
ENST00000420653.1
BCL2L1
BCL2-like 1
chr1_-_23521222 0.42 ENST00000374619.1
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr3_-_93747425 0.42 ENST00000315099.2
STX19
syntaxin 19
chr4_+_81951957 0.41 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr5_+_155753745 0.40 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr3_-_27763803 0.40 ENST00000449599.1
EOMES
eomesodermin
chr1_+_163038565 0.40 ENST00000421743.2
RGS4
regulator of G-protein signaling 4
chrX_-_15619076 0.40 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr12_-_100656134 0.39 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr1_-_85870177 0.39 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_-_26056695 0.39 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr19_-_42348692 0.39 ENST00000330743.3
ENST00000601246.1
LYPD4
LY6/PLAUR domain containing 4
chrX_+_10124977 0.39 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr15_+_43885252 0.39 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr6_+_123100853 0.38 ENST00000356535.4
FABP7
fatty acid binding protein 7, brain
chr3_+_148545586 0.38 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr3_+_94657086 0.38 ENST00000463200.1
LINC00879
long intergenic non-protein coding RNA 879
chr19_+_52772821 0.38 ENST00000439461.1
ZNF766
zinc finger protein 766
chr11_-_61735029 0.37 ENST00000526640.1
FTH1
ferritin, heavy polypeptide 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.8 2.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.7 2.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.6 2.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.6 1.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.5 7.1 GO:0006108 malate metabolic process(GO:0006108)
0.4 1.2 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4 1.6 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.4 1.1 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.3 2.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.5 GO:0006740 NADPH regeneration(GO:0006740)
0.3 1.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.5 GO:0043366 beta selection(GO:0043366)
0.2 2.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.0 GO:1904383 response to sodium phosphate(GO:1904383)
0.2 0.6 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 1.5 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.2 0.7 GO:0071288 T-helper 1 cell lineage commitment(GO:0002296) cellular response to mercury ion(GO:0071288)
0.2 0.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.3 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 1.7 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 9.1 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 0.4 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.7 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.3 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.7 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.6 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1 1.0 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.8 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.8 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 2.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.4 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.2 GO:0035922 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.6 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.9 GO:0006069 ethanol oxidation(GO:0006069)
0.1 2.0 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.6 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.4 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.8 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.7 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.8 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.3 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.9 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.5 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.9 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.8 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.4 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.7 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.7 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 2.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.9 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 2.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.7 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 1.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 1.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0050778 positive regulation of immune response(GO:0050778)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.9 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.6 GO:0090277 positive regulation of peptide hormone secretion(GO:0090277)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 1.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 2.4 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 2.1 GO:0071953 elastic fiber(GO:0071953)
0.2 0.6 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.2 0.7 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 1.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.7 GO:0097433 dense body(GO:0097433)
0.1 1.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.3 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 2.3 GO:0005861 troponin complex(GO:0005861)
0.1 0.4 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 1.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 1.6 GO:0036038 MKS complex(GO:0036038)
0.1 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 2.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 5.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 1.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 2.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 1.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 3.4 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 2.0 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 7.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
1.6 10.9 GO:0004127 cytidylate kinase activity(GO:0004127)
1.0 7.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.6 2.3 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.5 1.5 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 2.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 0.8 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 0.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 1.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 1.6 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 0.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 1.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 0.6 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.6 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 1.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 0.7 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.2 0.7 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 0.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.5 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.4 GO:0000150 recombinase activity(GO:0000150)
0.1 4.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.6 GO:0060230 lipase binding(GO:0035473) lipoprotein lipase activator activity(GO:0060230)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 2.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 3.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 1.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 4.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 0.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 13.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 2.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly