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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NFE2L1

Z-value: 0.67

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
ENSG00000082641.11 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46126135_46126152,
hg19_v2_chr17_+_46125707_46125746
0.402.9e-02Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_113594279 1.61 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr1_+_203651937 1.52 ENST00000341360.2
ATPase, Ca++ transporting, plasma membrane 4
chr1_-_152131703 1.46 ENST00000316073.3
repetin
chr1_-_153113927 1.32 ENST00000368752.4
small proline-rich protein 2B
chr19_-_36019123 1.30 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr12_-_91539918 1.26 ENST00000548218.1
decorin
chr2_-_161056762 1.24 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr11_-_125366089 1.20 ENST00000366139.3
ENST00000278919.3
fasciculation and elongation protein zeta 1 (zygin I)
chr16_+_8814563 1.13 ENST00000425191.2
ENST00000569156.1
4-aminobutyrate aminotransferase
chr19_+_35645618 1.09 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr15_+_45406519 1.07 ENST00000323030.5
dual oxidase maturation factor 2
chr7_+_80275752 0.98 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr2_-_161056802 0.98 ENST00000283249.2
ENST00000409872.1
integrin, beta 6
chr7_-_121944491 0.92 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr6_+_74405501 0.90 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr11_+_35201826 0.86 ENST00000531873.1
CD44 molecule (Indian blood group)
chr11_-_107729887 0.81 ENST00000525815.1
solute carrier family 35, member F2
chr11_+_35198243 0.76 ENST00000528455.1
CD44 molecule (Indian blood group)
chr1_+_84630053 0.74 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr15_-_45406385 0.72 ENST00000389039.6
dual oxidase 2
chrX_+_135279179 0.71 ENST00000370676.3
four and a half LIM domains 1
chr12_+_41086297 0.71 ENST00000551295.2
contactin 1
chr6_+_74405804 0.69 ENST00000287097.5
CD109 molecule
chr7_+_80275621 0.68 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr4_+_169013666 0.66 ENST00000359299.3
annexin A10
chr11_+_35211511 0.65 ENST00000524922.1
CD44 molecule (Indian blood group)
chr12_+_22778291 0.65 ENST00000545979.1
ethanolamine kinase 1
chr15_-_81616446 0.64 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr3_-_47950745 0.62 ENST00000429422.1
microtubule-associated protein 4
chr7_-_41742697 0.61 ENST00000242208.4
inhibin, beta A
chr11_+_35198118 0.61 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chrX_+_135278908 0.61 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr2_+_113735575 0.60 ENST00000376489.2
ENST00000259205.4
interleukin 36, gamma
chr4_+_74606223 0.60 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr12_-_91572278 0.60 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chr1_+_84630645 0.58 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr11_+_57308979 0.58 ENST00000457912.1
smoothelin-like 1
chr15_-_45406348 0.57 ENST00000603300.1
dual oxidase 2
chr1_+_26605618 0.57 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr8_+_7738726 0.56 ENST00000314357.3
defensin, beta 103A
chr19_-_51538118 0.55 ENST00000529888.1
kallikrein-related peptidase 12
chr17_-_64216748 0.55 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr17_+_42081914 0.53 ENST00000293404.3
ENST00000589767.1
N-acetylglutamate synthase
chr7_+_150811705 0.53 ENST00000335367.3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr8_-_7287870 0.53 ENST00000318124.3
defensin, beta 103B
chr12_-_91576750 0.52 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
decorin
chr19_-_51538148 0.51 ENST00000319590.4
ENST00000250351.4
kallikrein-related peptidase 12
chr12_-_52887034 0.51 ENST00000330722.6
keratin 6A
chr1_+_45265897 0.51 ENST00000372201.4
polo-like kinase 3
chr1_+_192127578 0.50 ENST00000367460.3
regulator of G-protein signaling 18
chr10_+_5566916 0.50 ENST00000315238.1
calmodulin-like 3
chr19_+_15052301 0.49 ENST00000248072.3
olfactory receptor, family 7, subfamily C, member 2
chr6_-_32145861 0.49 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr8_-_133123406 0.49 ENST00000434736.2
HERV-H LTR-associating 1
chr17_+_40610862 0.49 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATPase, H+ transporting, lysosomal V0 subunit a1
chrX_+_99899180 0.48 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr19_+_11200038 0.48 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
low density lipoprotein receptor
chr11_+_35211429 0.48 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr8_+_10530133 0.48 ENST00000304519.5
chromosome 8 open reading frame 74
chr2_+_228337079 0.47 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
ArfGAP with FG repeats 1
chr12_-_95510743 0.47 ENST00000551521.1
FYVE, RhoGEF and PH domain containing 6
chr9_-_128246769 0.46 ENST00000444226.1
mitogen-activated protein kinase associated protein 1
chr11_+_117947724 0.46 ENST00000534111.1
transmembrane protease, serine 4
chr11_+_59522837 0.46 ENST00000437946.2
syntaxin 3
chr12_-_54813229 0.46 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr7_-_142247606 0.45 ENST00000390361.3
T cell receptor beta variable 7-3
chr1_+_46806452 0.44 ENST00000536062.1
NOP2/Sun domain family, member 4
chr4_+_144303093 0.44 ENST00000505913.1
GRB2-associated binding protein 1
chr19_+_50706866 0.44 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr22_-_32651326 0.43 ENST00000266086.4
solute carrier family 5 (glucose activated ion channel), member 4
chr19_-_43383789 0.43 ENST00000595356.1
pregnancy specific beta-1-glycoprotein 1
chr11_+_117947782 0.43 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
transmembrane protease, serine 4
chr12_-_123187890 0.42 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr8_-_93029520 0.41 ENST00000521553.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_62439037 0.41 ENST00000545929.1
InaD-like (Drosophila)
chr14_+_22356029 0.40 ENST00000390437.2
T cell receptor alpha variable 12-2
chr12_-_102874330 0.40 ENST00000307046.8
insulin-like growth factor 1 (somatomedin C)
chr2_+_87754887 0.40 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
long intergenic non-protein coding RNA 152
chr14_+_22615942 0.40 ENST00000390457.2
T cell receptor alpha variable 27
chr15_+_68582544 0.40 ENST00000566008.1
fem-1 homolog b (C. elegans)
chr21_-_33975547 0.39 ENST00000431599.1
chromosome 21 open reading frame 59
chr15_+_80215113 0.39 ENST00000560255.1
chromosome 15 open reading frame 37
chr14_+_22977587 0.39 ENST00000390504.1
T cell receptor alpha joining 33
chr3_-_47934234 0.38 ENST00000420772.2
microtubule-associated protein 4
chr4_-_103998439 0.38 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr6_-_43595039 0.37 ENST00000307114.7
GTP binding protein 2
chrX_+_47078069 0.37 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
cyclin-dependent kinase 16
chr6_-_29324054 0.37 ENST00000543825.1
olfactory receptor, family 5, subfamily V, member 1
chr1_-_214638146 0.37 ENST00000543945.1
protein tyrosine phosphatase, non-receptor type 14
chr14_+_79746249 0.37 ENST00000428277.2
neurexin 3
chr12_-_102874102 0.37 ENST00000392905.2
insulin-like growth factor 1 (somatomedin C)
chr2_+_87808725 0.37 ENST00000413202.1
long intergenic non-protein coding RNA 152
chr16_+_81348528 0.36 ENST00000568107.2
gigaxonin
chr10_+_81272287 0.36 ENST00000520547.2
eukaryotic translation initiation factor 5A-like 1
chr18_+_34124507 0.35 ENST00000591635.1
formin homology 2 domain containing 3
chr8_+_104831472 0.35 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chr11_+_117063295 0.35 ENST00000525478.1
ENST00000532062.1
SID1 transmembrane family, member 2
chr2_+_87755054 0.35 ENST00000423846.1
long intergenic non-protein coding RNA 152
chr9_+_139847347 0.35 ENST00000371632.3
lipocalin 12
chr12_-_123201337 0.34 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr11_-_82708519 0.34 ENST00000534301.1
RAB30, member RAS oncogene family
chr1_-_156265438 0.34 ENST00000362007.1
chromosome 1 open reading frame 85
chrX_+_70503037 0.34 ENST00000535149.1
non-POU domain containing, octamer-binding
chr3_+_52350335 0.34 ENST00000420323.2
dynein, axonemal, heavy chain 1
chrX_-_48814278 0.33 ENST00000455452.1
OTU domain containing 5
chr1_-_94312706 0.33 ENST00000370244.1
breast cancer anti-estrogen resistance 3
chr19_-_42192096 0.33 ENST00000602225.1
carcinoembryonic antigen-related cell adhesion molecule 7
chr10_-_115904361 0.33 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr4_+_123300121 0.32 ENST00000446706.1
ENST00000296513.2
adenosine deaminase domain containing 1 (testis-specific)
chr16_-_15180257 0.32 ENST00000540462.1
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_+_28586006 0.32 ENST00000253063.3
sestrin 2
chr11_+_60197040 0.32 ENST00000300190.2
membrane-spanning 4-domains, subfamily A, member 5
chrX_-_48814810 0.32 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTU domain containing 5
chr12_-_91574142 0.32 ENST00000547937.1
decorin
chr2_+_87754989 0.32 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr17_+_26662597 0.31 ENST00000544907.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_113258090 0.31 ENST00000309276.6
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr15_-_27018884 0.31 ENST00000299267.4
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_-_70781087 0.31 ENST00000394241.3
ENST00000295400.6
transforming growth factor, alpha
chr16_-_20681177 0.31 ENST00000524149.1
acyl-CoA synthetase medium-chain family member 1
chr19_+_11546153 0.30 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
protein kinase C substrate 80K-H
chr1_+_29241027 0.30 ENST00000373797.1
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr9_+_130213774 0.30 ENST00000373324.4
ENST00000323301.4
leucine rich repeat and sterile alpha motif containing 1
chr12_-_7596735 0.30 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163 molecule-like 1
chr1_+_64669294 0.29 ENST00000371077.5
ubiquitin-conjugating enzyme E2U (putative)
chr17_+_73663470 0.29 ENST00000583536.1
SAP30 binding protein
chr18_+_55888767 0.28 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_+_132455118 0.28 ENST00000458028.1
long intergenic non-protein coding RNA 1013
chr9_+_125027127 0.28 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
mitochondrial ribosome recycling factor
chr2_+_242167319 0.28 ENST00000601871.1
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr6_+_63921351 0.28 ENST00000370659.1
FK506 binding protein 1C
chr3_+_130650738 0.28 ENST00000504612.1
ATPase, Ca++ transporting, type 2C, member 1
chr6_+_63921399 0.28 ENST00000356170.3
FK506 binding protein 1C
chr1_-_119682812 0.28 ENST00000537870.1
tryptophanyl tRNA synthetase 2, mitochondrial
chr2_+_234602305 0.28 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr16_-_20364122 0.28 ENST00000396138.4
ENST00000577168.1
uromodulin
chr5_-_112630598 0.28 ENST00000302475.4
mutated in colorectal cancers
chr1_+_159175201 0.27 ENST00000368121.2
Duffy blood group, atypical chemokine receptor
chr19_+_11546093 0.27 ENST00000591462.1
protein kinase C substrate 80K-H
chr2_+_201994208 0.27 ENST00000440180.1
CASP8 and FADD-like apoptosis regulator
chr20_+_43992094 0.27 ENST00000453003.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chrX_+_47077632 0.27 ENST00000457458.2
cyclin-dependent kinase 16
chr2_-_220119280 0.27 ENST00000392088.2
tubulin, alpha 4a
chr12_-_91573132 0.27 ENST00000550563.1
ENST00000546370.1
decorin
chr9_+_124103625 0.27 ENST00000594963.1
Uncharacterized protein
chr6_+_143381979 0.27 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
androgen-induced 1
chr16_+_2286726 0.27 ENST00000382437.4
ENST00000569184.1
deoxyribonuclease I-like 2
chrX_+_107069063 0.26 ENST00000262843.6
midline 2
chr6_-_41130914 0.26 ENST00000373113.3
ENST00000338469.3
triggering receptor expressed on myeloid cells 2
chr2_+_190306159 0.26 ENST00000314761.4
WD repeat domain 75
chr4_+_3344141 0.26 ENST00000306648.7
regulator of G-protein signaling 12
chrX_-_49965663 0.26 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
A kinase (PRKA) anchor protein 4
chr1_-_6445809 0.26 ENST00000377855.2
acyl-CoA thioesterase 7
chr12_-_10324716 0.25 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr16_+_3068393 0.25 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr19_-_42192189 0.25 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
carcinoembryonic antigen-related cell adhesion molecule 7
chr1_+_110254850 0.25 ENST00000369812.5
ENST00000256593.3
ENST00000369813.1
glutathione S-transferase mu 5
chr15_+_28624878 0.25 ENST00000450328.2
golgin A8 family, member F
chr2_+_201994042 0.25 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr12_+_21525818 0.24 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr6_-_131321863 0.24 ENST00000528282.1
erythrocyte membrane protein band 4.1-like 2
chr2_+_234545092 0.24 ENST00000344644.5
UDP glucuronosyltransferase 1 family, polypeptide A10
chr17_+_26662730 0.24 ENST00000226225.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr15_+_93447675 0.24 ENST00000536619.1
chromodomain helicase DNA binding protein 2
chr3_-_118753716 0.24 ENST00000393775.2
immunoglobulin superfamily, member 11
chr11_+_126139005 0.23 ENST00000263578.5
ENST00000442061.2
ENST00000532125.1
FAD-dependent oxidoreductase domain containing 1
chr4_+_71494461 0.23 ENST00000396073.3
enamelin
chr4_+_75858318 0.23 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr1_-_157811588 0.23 ENST00000368174.4
CD5 molecule-like
chr3_-_105588231 0.23 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr16_-_58768177 0.23 ENST00000434819.2
ENST00000245206.5
glutamic-oxaloacetic transaminase 2, mitochondrial
chr4_+_69962185 0.23 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr1_-_204135450 0.23 ENST00000272190.8
ENST00000367195.2
renin
chr3_-_16306432 0.23 ENST00000383775.4
ENST00000488423.1
diphthamide biosynthesis 3
chr6_+_160183492 0.23 ENST00000541436.1
acetyl-CoA acetyltransferase 2
chr1_-_39395165 0.23 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr3_-_118753626 0.22 ENST00000489689.1
immunoglobulin superfamily, member 11
chr19_-_44160768 0.22 ENST00000593447.1
plasminogen activator, urokinase receptor
chr7_+_142636603 0.22 ENST00000409607.3
chromosome 7 open reading frame 34
chr1_+_207038699 0.22 ENST00000367098.1
interleukin 20
chrX_-_30993201 0.22 ENST00000288422.2
ENST00000378932.2
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr17_-_53800217 0.22 ENST00000424486.2
transmembrane protein 100
chr14_+_24779376 0.22 ENST00000530080.1
leukotriene B4 receptor 2
chr11_+_22359562 0.22 ENST00000263160.3
solute carrier family 17 (vesicular glutamate transporter), member 6
chr2_+_74120094 0.22 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
actin, gamma 2, smooth muscle, enteric
chr18_+_657733 0.22 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr14_+_68189190 0.22 ENST00000539142.1
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr16_-_20364030 0.22 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
uromodulin
chr6_-_137494775 0.22 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
interleukin 22 receptor, alpha 2
chr17_+_57297807 0.22 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
glycerophosphodiester phosphodiesterase domain containing 1
chrX_+_78426469 0.22 ENST00000276077.1
G protein-coupled receptor 174
chr19_-_35992780 0.22 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr3_-_127541194 0.22 ENST00000453507.2
monoglyceride lipase
chr20_-_43150601 0.22 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr2_-_89459813 0.22 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr5_+_40909354 0.21 ENST00000313164.9
complement component 7
chr6_+_117586713 0.21 ENST00000352536.3
ENST00000326274.5
vestigial like 2 (Drosophila)
chr8_+_22853345 0.21 ENST00000522948.1
Rho-related BTB domain containing 2
chr9_-_36276966 0.21 ENST00000543356.2
ENST00000396594.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr12_+_72080253 0.21 ENST00000549735.1
transmembrane protein 19

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.5 1.5 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.4 3.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 1.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 1.7 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 0.8 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.3 1.6 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.3 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.2 0.6 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 2.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 3.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.3 GO:0097338 response to clozapine(GO:0097338)
0.2 0.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 0.5 GO:2000777 endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.8 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 0.5 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 0.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 1.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.5 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.7 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.4 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.3 GO:0032499 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.4 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 0.3 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.1 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1 0.4 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.2 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.6 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.2 GO:0019860 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860) intestinal epithelial cell maturation(GO:0060574)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 0.2 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.2 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.1 0.5 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.5 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.5 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.6 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:2001214 arterial endothelial cell differentiation(GO:0060842) positive regulation of vasculogenesis(GO:2001214)
0.0 3.4 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.8 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.7 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 1.3 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:2000197 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.5 GO:0040008 regulation of growth(GO:0040008)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.0 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0019932 second-messenger-mediated signaling(GO:0019932)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807) SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0061470 astrocyte cell migration(GO:0043615) T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.4 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.5 3.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 3.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.6 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.7 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 0.5 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 0.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.8 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 3.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 2.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 1.1 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 1.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.4 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.3 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 3.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 2.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.2 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.4 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.7 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.4 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 1.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 1.9 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID EPO PATHWAY EPO signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport