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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NFIA

Z-value: 0.96

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Transcription factors associated with NFIA

Gene Symbol Gene ID Gene Info
NFIA
ENSG00000162599.11 nuclear factor I A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIAhg19_v2_chr1_+_61869748_61869782-0.641.3e-04Click!

Activity profile of NFIA motif

Sorted Z-values of NFIA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_41742697 5.98 ENST00000242208.4
INHBA
inhibin, beta A
chr2_-_31637560 5.61 ENST00000379416.3
XDH
xanthine dehydrogenase
chr13_-_20805109 3.82 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr4_-_57547454 2.54 ENST00000556376.2
HOPX
HOP homeobox
chr4_-_57547870 2.53 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr2_-_113542063 2.30 ENST00000263339.3
IL1A
interleukin 1, alpha
chrX_+_135251783 2.28 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr10_+_102106829 2.27 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chrX_+_135252050 2.19 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr7_-_27135591 2.13 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chrX_+_135251835 2.10 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr13_+_78109884 2.08 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr5_+_135394840 2.07 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr16_-_55867146 2.06 ENST00000422046.2
CES1
carboxylesterase 1
chr16_-_55866997 2.04 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr13_+_78109804 2.01 ENST00000535157.1
SCEL
sciellin
chr19_+_41725088 1.98 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr3_-_74570291 1.95 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr10_-_100995540 1.93 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chr21_-_44846999 1.86 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr5_-_95018660 1.85 ENST00000395899.3
ENST00000274432.8
SPATA9
spermatogenesis associated 9
chr15_+_67458357 1.84 ENST00000537194.2
SMAD3
SMAD family member 3
chr12_-_122238464 1.82 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr18_-_31802056 1.68 ENST00000538587.1
NOL4
nucleolar protein 4
chr3_+_52350335 1.60 ENST00000420323.2
DNAH1
dynein, axonemal, heavy chain 1
chr8_+_124194875 1.55 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr9_-_99064386 1.54 ENST00000375262.2
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr11_-_58343319 1.53 ENST00000395074.2
LPXN
leupaxin
chr2_+_102953608 1.51 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr18_+_61143994 1.51 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_+_57828521 1.51 ENST00000309668.2
INHBC
inhibin, beta C
chr19_-_40324767 1.48 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr18_+_61254570 1.48 ENST00000344731.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr8_+_124194752 1.45 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr18_+_61254534 1.43 ENST00000269489.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr4_-_103266355 1.41 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr14_-_24732368 1.40 ENST00000544573.1
TGM1
transglutaminase 1
chr14_+_75746340 1.40 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr11_-_66675371 1.38 ENST00000393955.2
PC
pyruvate carboxylase
chr2_-_190044480 1.37 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr5_-_43313574 1.36 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr3_-_47950745 1.34 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr14_-_75079026 1.34 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr14_-_24732403 1.33 ENST00000206765.6
TGM1
transglutaminase 1
chr14_+_75746781 1.33 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr15_+_41549105 1.29 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr11_-_128392085 1.28 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr12_-_95510743 1.18 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr14_-_64194745 1.17 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr1_+_209878182 1.13 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr3_+_19189946 1.12 ENST00000328405.2
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr9_-_99064429 1.11 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr13_-_40177261 1.05 ENST00000379589.3
LHFP
lipoma HMGIC fusion partner
chr12_-_53207842 1.05 ENST00000458244.2
KRT4
keratin 4
chr18_-_31802282 1.04 ENST00000535475.1
NOL4
nucleolar protein 4
chr2_+_17721230 1.02 ENST00000457525.1
VSNL1
visinin-like 1
chr17_+_16120512 1.01 ENST00000581006.1
ENST00000584797.1
ENST00000498772.2
ENST00000225609.5
ENST00000395844.4
ENST00000477745.1
PIGL
phosphatidylinositol glycan anchor biosynthesis, class L
chr2_+_136289030 0.98 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr17_-_8113542 0.98 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr1_+_24646002 0.97 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr7_+_147830776 0.96 ENST00000538075.1
CNTNAP2
contactin associated protein-like 2
chr4_-_103266626 0.95 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_+_33037652 0.93 ENST00000311388.3
DEPDC7
DEP domain containing 7
chr17_-_72358001 0.91 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr1_-_24469602 0.91 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr15_+_67418047 0.91 ENST00000540846.2
SMAD3
SMAD family member 3
chr1_-_204116078 0.90 ENST00000367198.2
ENST00000452983.1
ETNK2
ethanolamine kinase 2
chr12_-_53171128 0.89 ENST00000332411.2
KRT76
keratin 76
chr19_-_13227534 0.87 ENST00000588229.1
ENST00000357720.4
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr8_+_32579341 0.86 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr19_-_13227463 0.86 ENST00000437766.1
ENST00000221504.8
TRMT1
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr8_-_131399110 0.85 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr12_-_10251603 0.84 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr19_-_43969796 0.83 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr13_-_36050819 0.83 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr19_-_40324255 0.83 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr6_-_30658745 0.82 ENST00000376420.5
ENST00000376421.5
NRM
nurim (nuclear envelope membrane protein)
chr10_+_105005644 0.81 ENST00000441178.2
RP11-332O19.5
ribulose-5-phosphate-3-epimerase-like 1
chr17_-_39661849 0.81 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr6_-_32784687 0.81 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr16_-_79634595 0.81 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr12_-_28125638 0.80 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr4_-_103266219 0.80 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr4_+_166248775 0.80 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr5_-_77844974 0.80 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr6_-_155776966 0.80 ENST00000159060.2
NOX3
NADPH oxidase 3
chr20_-_57607347 0.80 ENST00000395663.1
ENST00000395659.1
ENST00000243997.3
ATP5E
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr16_+_8891670 0.79 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2
phosphomannomutase 2
chr10_+_135340859 0.78 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr5_+_147648393 0.78 ENST00000511106.1
ENST00000398450.4
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr22_-_38699003 0.78 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr3_-_37216055 0.74 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chrX_+_12924732 0.74 ENST00000218032.6
ENST00000311912.5
TLR8
toll-like receptor 8
chr19_+_41725140 0.73 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr12_+_56435637 0.72 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr10_+_5005598 0.71 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr1_+_107683644 0.71 ENST00000370067.1
NTNG1
netrin G1
chr17_-_38657849 0.71 ENST00000254051.6
TNS4
tensin 4
chr2_-_228028829 0.71 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr12_-_10251576 0.70 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr6_+_42989344 0.70 ENST00000244496.5
RRP36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr1_-_155224699 0.69 ENST00000491082.1
FAM189B
family with sequence similarity 189, member B
chr17_+_19314505 0.69 ENST00000461366.1
RNF112
ring finger protein 112
chr3_+_132843652 0.69 ENST00000508711.1
TMEM108
transmembrane protein 108
chr10_+_5238793 0.69 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr17_+_7323634 0.69 ENST00000323675.3
SPEM1
spermatid maturation 1
chr12_-_99038732 0.69 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr9_+_27109133 0.68 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr7_+_129015484 0.68 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr11_+_193065 0.67 ENST00000342878.2
SCGB1C1
secretoglobin, family 1C, member 1
chr1_+_86934526 0.67 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr14_+_96722539 0.67 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr11_+_34654011 0.66 ENST00000531794.1
EHF
ets homologous factor
chr10_+_74653330 0.66 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr1_+_107683436 0.66 ENST00000370068.1
NTNG1
netrin G1
chr11_-_113577014 0.65 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr4_+_93225550 0.65 ENST00000282020.4
GRID2
glutamate receptor, ionotropic, delta 2
chr11_-_113577052 0.64 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr18_+_61144160 0.64 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr17_-_39769005 0.64 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr10_-_75226166 0.63 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr4_+_144354644 0.62 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr12_+_113682066 0.62 ENST00000392569.4
ENST00000552542.1
TPCN1
two pore segment channel 1
chr4_-_157892055 0.62 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr3_+_152017924 0.62 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1
muscleblind-like splicing regulator 1
chr17_-_39093672 0.61 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr18_+_29171689 0.61 ENST00000237014.3
TTR
transthyretin
chr10_+_24528108 0.61 ENST00000438429.1
KIAA1217
KIAA1217
chr15_+_74165945 0.60 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1D21
TBC1 domain family, member 21
chr7_-_27183263 0.60 ENST00000222726.3
HOXA5
homeobox A5
chr9_+_17134980 0.59 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr14_+_73704201 0.59 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr15_+_81475047 0.59 ENST00000559388.1
IL16
interleukin 16
chr3_-_194188956 0.58 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr7_+_129932974 0.58 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4
carboxypeptidase A4
chr17_+_54671047 0.58 ENST00000332822.4
NOG
noggin
chr9_-_98784042 0.58 ENST00000412122.2
LINC00092
long intergenic non-protein coding RNA 92
chr7_-_105319536 0.57 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr22_-_48943199 0.57 ENST00000407505.3
CTA-299D3.8
Uncharacterized protein
chr12_+_93965609 0.56 ENST00000549887.1
ENST00000551556.1
SOCS2
suppressor of cytokine signaling 2
chr2_+_33701286 0.56 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_-_44388899 0.56 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr3_-_192635943 0.56 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr7_+_134528635 0.55 ENST00000445569.2
CALD1
caldesmon 1
chr8_+_38586068 0.55 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr10_+_11206925 0.55 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr7_-_19184929 0.54 ENST00000275461.3
FERD3L
Fer3-like bHLH transcription factor
chrX_+_49832231 0.54 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr3_+_111718173 0.54 ENST00000494932.1
TAGLN3
transgelin 3
chr19_-_13710678 0.53 ENST00000592864.1
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr1_+_11539204 0.53 ENST00000294484.6
ENST00000389575.3
PTCHD2
patched domain containing 2
chr10_+_99609996 0.53 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr4_+_74269956 0.52 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr19_+_41256764 0.52 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr2_+_30569506 0.52 ENST00000421976.2
AC109642.1
AC109642.1
chr20_+_42965626 0.52 ENST00000217043.2
R3HDML
R3H domain containing-like
chr9_-_72287191 0.52 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr11_-_2170786 0.52 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr15_+_38544476 0.51 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr12_+_56521840 0.51 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr4_-_76928641 0.51 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr10_-_104597286 0.50 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chrX_+_37639302 0.50 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr19_+_49258775 0.49 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr19_-_46296011 0.49 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr6_+_22569784 0.49 ENST00000510882.2
HDGFL1
hepatoma derived growth factor-like 1
chr10_+_74033672 0.49 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr22_+_24990746 0.49 ENST00000456869.1
ENST00000411974.1
GGT1
gamma-glutamyltransferase 1
chr20_-_14318248 0.49 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr3_-_171177852 0.49 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr16_-_19725899 0.49 ENST00000567367.1
KNOP1
lysine-rich nucleolar protein 1
chr3_-_52002403 0.49 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr4_+_156824840 0.48 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr16_-_58328923 0.48 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr18_+_59000815 0.47 ENST00000262717.4
CDH20
cadherin 20, type 2
chr2_-_219925189 0.47 ENST00000295731.6
IHH
indian hedgehog
chr12_-_131200810 0.47 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chr8_+_97597148 0.47 ENST00000521590.1
SDC2
syndecan 2
chr19_+_36249057 0.47 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
C19orf55
chromosome 19 open reading frame 55
chr16_-_58328870 0.47 ENST00000543437.1
PRSS54
protease, serine, 54
chr6_+_69942298 0.46 ENST00000238918.8
BAI3
brain-specific angiogenesis inhibitor 3
chr19_-_15560730 0.46 ENST00000389282.4
ENST00000263381.7
WIZ
widely interspaced zinc finger motifs
chr14_-_98444461 0.46 ENST00000499006.2
C14orf64
chromosome 14 open reading frame 64
chr19_+_41257084 0.46 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr14_+_23299088 0.45 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr14_+_93897199 0.45 ENST00000553484.1
UNC79
unc-79 homolog (C. elegans)
chr3_+_119013185 0.45 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr13_-_46716969 0.45 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_33463210 0.45 ENST00000590281.1
C19orf40
chromosome 19 open reading frame 40
chr4_+_169552748 0.45 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr4_-_114900831 0.45 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr19_+_49259325 0.45 ENST00000222157.3
FGF21
fibroblast growth factor 21
chr12_+_56324933 0.45 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr3_-_47934234 0.44 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr14_-_95236551 0.44 ENST00000238558.3
GSC
goosecoid homeobox
chr3_+_101498074 0.44 ENST00000273347.5
ENST00000474165.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr3_+_101498269 0.44 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chrX_+_105192423 0.44 ENST00000540278.1
NRK
Nik related kinase
chr1_-_203320617 0.44 ENST00000354955.4
FMOD
fibromodulin
chr5_+_122847908 0.43 ENST00000511130.2
ENST00000512718.3
CSNK1G3
casein kinase 1, gamma 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.4 5.6 GO:0046110 xanthine metabolic process(GO:0046110)
1.0 4.2 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.9 2.7 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.8 2.3 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.6 2.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.5 1.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.5 1.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 3.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.4 1.2 GO:0060435 bronchiole development(GO:0060435)
0.4 2.3 GO:2000391 positive regulation of neutrophil extravasation(GO:2000391)
0.4 2.6 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.4 1.9 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.3 0.7 GO:0010165 response to X-ray(GO:0010165)
0.3 2.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 1.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 1.8 GO:0051012 microtubule sliding(GO:0051012)
0.3 1.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.3 3.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3 0.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 1.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.3 3.0 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.3 1.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.4 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 2.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.2 0.8 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 1.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 5.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.2 1.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 0.9 GO:1904640 response to methionine(GO:1904640)
0.2 0.6 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.2 0.7 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2 0.5 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 0.5 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.5 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.2 0.8 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.3 GO:0030578 PML body organization(GO:0030578)
0.2 0.5 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.4 GO:0036309 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.1 0.4 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.6 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.9 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.8 GO:0010193 response to ozone(GO:0010193)
0.1 0.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 1.0 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 1.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.2 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.6 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.3 GO:0061056 sclerotome development(GO:0061056)
0.1 1.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 1.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.3 GO:0001080 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 1.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 6.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 1.1 GO:0009629 response to gravity(GO:0009629)
0.1 0.7 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 0.9 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.6 GO:0071964 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 1.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.9 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 3.8 GO:0051602 response to electrical stimulus(GO:0051602)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.3 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.3 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 1.0 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.5 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 1.0 GO:0051546 keratinocyte migration(GO:0051546)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 2.4 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.3 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 1.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.3 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 1.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0018394 peptidyl-lysine acetylation(GO:0018394)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 2.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.0 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 1.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 4.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.7 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.7 GO:0060347 heart trabecula formation(GO:0060347)
0.0 1.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.8 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 1.0 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.4 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 1.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 2.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 2.7 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.7 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 6.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.3 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.7 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.5 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) positive regulation of developmental pigmentation(GO:0048087) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0021861 forebrain radial glial cell differentiation(GO:0021861) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 0.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.0 0.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 1.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.9 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146) keratan sulfate metabolic process(GO:0042339)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.6 GO:0036156 inner dynein arm(GO:0036156)
0.3 2.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 2.7 GO:0035976 AP1 complex(GO:0035976)
0.2 0.5 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.2 3.8 GO:0005922 connexon complex(GO:0005922)
0.2 2.7 GO:0033643 host cell part(GO:0033643)
0.1 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 1.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 7.3 GO:0001533 cornified envelope(GO:0001533)
0.1 3.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.2 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.0 3.3 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 2.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.3 GO:0005884 actin filament(GO:0005884)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 3.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 5.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 7.6 GO:0005925 focal adhesion(GO:0005925)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.8 4.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.6 5.6 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.6 2.3 GO:0030305 heparanase activity(GO:0030305)
0.6 2.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.5 1.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.5 1.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.5 2.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.4 2.6 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.4 1.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4 1.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 2.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 0.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 0.7 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.2 0.7 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.2 2.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.5 GO:0070984 SET domain binding(GO:0070984)
0.2 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.4 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 1.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0016499 orexin receptor activity(GO:0016499)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 2.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.5 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.8 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 1.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.3 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 1.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.8 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004609 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.5 GO:0005113 patched binding(GO:0005113)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 4.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 4.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 1.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.1 GO:0046332 SMAD binding(GO:0046332)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 2.5 GO:0004713 protein tyrosine kinase activity(GO:0004713)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 5.2 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 6.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 5.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.4 5.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 3.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 3.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 2.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 2.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors