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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NFKB1

Z-value: 1.20

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Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
NFKB1
ENSG00000109320.7 nuclear factor kappa B subunit 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB1hg19_v2_chr4_+_103423055_1034231120.622.8e-04Click!

Activity profile of NFKB1 motif

Sorted Z-values of NFKB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_149792295 13.64 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr3_+_63638339 10.79 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr6_-_29527702 10.63 ENST00000377050.4
UBD
ubiquitin D
chr16_+_67465016 8.78 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr16_-_66959429 8.15 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr5_-_54468974 7.21 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr9_+_127615733 6.68 ENST00000373574.1
WDR38
WD repeat domain 38
chr19_+_45504688 5.09 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr6_+_135502466 4.87 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr6_+_32605195 4.85 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr10_+_12391481 4.64 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr17_+_40440481 4.55 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr6_-_109762344 4.34 ENST00000521072.2
ENST00000424445.2
ENST00000440797.2
PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr6_+_32821924 3.68 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr1_+_6845497 3.67 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr14_+_75536335 3.40 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr19_+_10527449 3.35 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr4_+_74735102 3.30 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr14_+_75536280 3.24 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr6_+_32605134 3.03 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr10_+_12391685 2.99 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr10_-_102089729 2.77 ENST00000465680.2
PKD2L1
polycystic kidney disease 2-like 1
chr6_+_29691198 2.73 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_+_29691056 2.73 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr15_+_76352178 2.72 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr1_+_6845578 2.64 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr17_+_7590734 2.63 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chrX_-_112084043 2.62 ENST00000304758.1
AMOT
angiomotin
chr2_-_217560248 2.59 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr1_+_54359854 2.58 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1
deiodinase, iodothyronine, type I
chr2_+_38893208 2.58 ENST00000410063.1
GALM
galactose mutarotase (aldose 1-epimerase)
chr8_+_104831554 2.44 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr16_+_50775948 2.37 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr14_+_75988768 2.34 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr12_+_52445191 2.30 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr6_-_111804905 2.26 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr1_+_6845384 2.23 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr1_+_100818156 2.16 ENST00000336454.3
CDC14A
cell division cycle 14A
chr16_-_53737795 2.10 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr16_-_53737722 2.09 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr1_+_201979645 2.01 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr8_+_86157699 1.93 ENST00000321764.3
CA13
carbonic anhydrase XIII
chr5_-_55290773 1.92 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr14_-_61190754 1.92 ENST00000216513.4
SIX4
SIX homeobox 4
chr6_+_29910301 1.87 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr16_+_50775971 1.86 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_57126482 1.85 ENST00000537605.1
ENST00000535318.2
CPNE2
copine II
chr17_-_56065484 1.78 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr11_-_75062829 1.78 ENST00000393505.4
ARRB1
arrestin, beta 1
chr2_-_157189180 1.76 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr16_+_57126428 1.73 ENST00000290776.8
CPNE2
copine II
chr2_+_97203082 1.71 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr7_+_69064300 1.63 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr20_-_62462566 1.63 ENST00000245663.4
ENST00000302995.2
ZBTB46
zinc finger and BTB domain containing 46
chr4_-_74904398 1.62 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr17_+_8924837 1.61 ENST00000173229.2
NTN1
netrin 1
chr6_+_138188551 1.60 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_+_75988851 1.60 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr7_-_127032363 1.59 ENST00000393312.1
ZNF800
zinc finger protein 800
chr2_+_97202480 1.56 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr11_+_102188272 1.52 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr6_+_80341000 1.51 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr6_+_18155632 1.49 ENST00000297792.5
KDM1B
lysine (K)-specific demethylase 1B
chr20_+_44746885 1.47 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr1_+_89990431 1.44 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr14_-_35873856 1.40 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr2_-_211036051 1.40 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr19_-_47734448 1.34 ENST00000439096.2
BBC3
BCL2 binding component 3
chr11_+_63997750 1.34 ENST00000321685.3
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr4_-_74964904 1.33 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr6_+_149068464 1.31 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr11_+_65292884 1.30 ENST00000527009.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr11_-_75062730 1.29 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr9_+_17579084 1.29 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr19_-_49149553 1.26 ENST00000084798.4
CA11
carbonic anhydrase XI
chr11_-_96076334 1.26 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr11_-_72853091 1.25 ENST00000311172.7
ENST00000409314.1
FCHSD2
FCH and double SH3 domains 2
chr15_-_27018884 1.24 ENST00000299267.4
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr20_-_50159198 1.24 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_+_211432593 1.23 ENST00000367006.4
RCOR3
REST corepressor 3
chr5_+_56469843 1.22 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr16_+_50776021 1.20 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr11_+_72525353 1.18 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
ATG16L2
autophagy related 16-like 2 (S. cerevisiae)
chr19_+_2476116 1.18 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr1_+_183441500 1.17 ENST00000456731.2
SMG7
SMG7 nonsense mediated mRNA decay factor
chr6_-_17706618 1.15 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr1_+_100818009 1.15 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr2_+_54951679 1.15 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr4_+_103422471 1.14 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr22_-_38349552 1.14 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23
chromosome 22 open reading frame 23
chr1_+_18434240 1.13 ENST00000251296.1
IGSF21
immunoglobin superfamily, member 21
chr14_-_24616426 1.10 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_-_46121554 1.10 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr12_-_55375622 1.10 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr11_+_65292538 1.09 ENST00000270176.5
ENST00000525364.1
ENST00000420247.2
ENST00000533862.1
ENST00000279270.6
ENST00000524944.1
SCYL1
SCY1-like 1 (S. cerevisiae)
chr6_-_44233361 1.08 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr17_-_7590745 1.07 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr19_+_35940486 1.05 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr2_+_208394616 1.05 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr1_+_38259540 1.03 ENST00000397631.3
MANEAL
mannosidase, endo-alpha-like
chr1_+_27114418 1.03 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr4_-_140098339 1.01 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_-_33555780 0.99 ENST00000254260.3
ENST00000400226.4
RHPN2
rhophilin, Rho GTPase binding protein 2
chr2_+_208394794 0.99 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1
cAMP responsive element binding protein 1
chr19_+_55795493 0.99 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr5_+_56469775 0.99 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr11_+_34642656 0.98 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr2_+_42721689 0.96 ENST00000405592.1
MTA3
metastasis associated 1 family, member 3
chr1_+_38259459 0.96 ENST00000373045.6
MANEAL
mannosidase, endo-alpha-like
chr13_-_30424821 0.95 ENST00000380680.4
UBL3
ubiquitin-like 3
chr19_-_4338783 0.95 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr17_-_7123021 0.94 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr11_-_77185094 0.93 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr5_-_135231516 0.89 ENST00000274520.1
IL9
interleukin 9
chr7_+_17338239 0.88 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr19_-_4338838 0.88 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr2_+_32853093 0.88 ENST00000448773.1
ENST00000317907.4
TTC27
tetratricopeptide repeat domain 27
chr20_+_44746939 0.86 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr1_+_27561007 0.86 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr2_-_152955537 0.84 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr9_-_124990680 0.82 ENST00000541397.2
ENST00000560485.1
LHX6
LIM homeobox 6
chr5_+_56469939 0.82 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr15_+_44719970 0.81 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_-_151299842 0.80 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr10_-_73533255 0.80 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr6_+_30850697 0.80 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_+_4634705 0.80 ENST00000575284.1
ENST00000573708.1
ENST00000293777.5
MED11
mediator complex subunit 11
chr17_-_7197881 0.79 ENST00000007699.5
YBX2
Y box binding protein 2
chr2_+_38893047 0.79 ENST00000272252.5
GALM
galactose mutarotase (aldose 1-epimerase)
chr4_-_122085469 0.79 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chrX_+_40440146 0.78 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr2_+_61108771 0.78 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr9_+_82188077 0.77 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_-_46142505 0.76 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr1_+_156123318 0.76 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr11_-_47400062 0.76 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_-_30080876 0.75 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr1_+_63833261 0.74 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr1_+_156123359 0.74 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr11_+_113930291 0.73 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr2_+_208394455 0.73 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr1_+_110453109 0.72 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr5_-_96143796 0.72 ENST00000296754.3
ERAP1
endoplasmic reticulum aminopeptidase 1
chr12_+_11802753 0.69 ENST00000396373.4
ETV6
ets variant 6
chr12_+_7052974 0.68 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr8_-_103668114 0.68 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr5_-_127418755 0.66 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
CTC-228N24.3
chr2_+_163175394 0.66 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr1_+_27561104 0.66 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr11_-_47399942 0.65 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr15_+_89346657 0.65 ENST00000439576.2
ACAN
aggrecan
chr6_-_27279949 0.65 ENST00000444565.1
ENST00000377451.2
POM121L2
POM121 transmembrane nucleoporin-like 2
chr15_-_77712477 0.65 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr11_-_46142615 0.65 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr11_+_560956 0.65 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr13_+_97874574 0.64 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr1_+_169077172 0.64 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr14_+_24616588 0.64 ENST00000324103.6
ENST00000559260.1
RNF31
ring finger protein 31
chr3_+_53195136 0.64 ENST00000394729.2
ENST00000330452.3
PRKCD
protein kinase C, delta
chr3_-_187455680 0.62 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr15_-_89438742 0.62 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr4_-_103748880 0.62 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_7053228 0.62 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr11_-_47400078 0.62 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr13_+_108922228 0.61 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr2_+_61108650 0.61 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr6_+_88299833 0.60 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
ORC3
origin recognition complex, subunit 3
chr11_+_118307179 0.60 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A
lysine (K)-specific methyltransferase 2A
chr3_-_50605150 0.59 ENST00000357203.3
C3orf18
chromosome 3 open reading frame 18
chr6_+_33168637 0.59 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr5_+_139781445 0.56 ENST00000532219.1
ENST00000394722.3
ANKHD1-EIF4EBP3
ANKHD1
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr15_+_85923797 0.56 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr12_+_7053172 0.56 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr6_+_33168597 0.55 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr7_+_101460882 0.55 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr3_+_9691117 0.55 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
MTMR14
myotubularin related protein 14
chr3_-_50605077 0.54 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr1_-_8000872 0.53 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr3_+_197518100 0.52 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr6_-_74230741 0.51 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_+_208394658 0.50 ENST00000421139.1
CREB1
cAMP responsive element binding protein 1
chr6_+_33378738 0.50 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr17_+_63133587 0.49 ENST00000449996.3
ENST00000262406.9
RGS9
regulator of G-protein signaling 9
chr1_+_183441618 0.49 ENST00000507691.2
ENST00000508461.1
ENST00000419169.1
ENST00000347615.2
ENST00000507469.1
ENST00000515829.2
SMG7
SMG7 nonsense mediated mRNA decay factor
chr11_-_65363259 0.49 ENST00000342202.4
KCNK7
potassium channel, subfamily K, member 7
chr4_-_185395672 0.49 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr12_-_24103954 0.48 ENST00000441133.2
ENST00000545921.1
SOX5
SRY (sex determining region Y)-box 5
chr13_+_39261224 0.48 ENST00000280481.7
FREM2
FRAS1 related extracellular matrix protein 2
chr1_+_183441600 0.47 ENST00000367537.3
SMG7
SMG7 nonsense mediated mRNA decay factor
chrX_+_130192318 0.47 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr1_+_100818484 0.47 ENST00000544534.1
CDC14A
cell division cycle 14A
chr5_+_54603566 0.46 ENST00000230640.5
SKIV2L2
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
chr17_+_21191341 0.46 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr15_-_71055878 0.45 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr16_+_67282853 0.45 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr3_+_49058444 0.44 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr11_-_133826852 0.44 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr9_-_117568365 0.44 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr5_+_139781393 0.42 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ANKHD1
ankyrin repeat and KH domain containing 1
chr1_-_44818599 0.42 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.6 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.1 10.6 GO:0070842 aggresome assembly(GO:0070842)
2.0 8.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.8 5.4 GO:1990108 protein linear deubiquitination(GO:1990108)
1.6 4.9 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.1 4.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.9 2.6 GO:0032203 telomere formation via telomerase(GO:0032203)
0.9 2.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.8 3.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.8 7.5 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.7 6.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.6 1.9 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.6 1.8 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.6 1.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.5 3.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.5 0.5 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.5 8.8 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.5 2.0 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.5 1.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.4 3.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.4 1.2 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.4 1.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.4 6.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.4 1.1 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.4 1.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3 2.3 GO:0033590 response to cobalamin(GO:0033590)
0.3 2.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 1.2 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.3 0.9 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.3 0.8 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 1.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3 3.1 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.3 1.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.3 1.9 GO:0036343 psychomotor behavior(GO:0036343)
0.3 2.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 0.7 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.2 3.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 1.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.2 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.2 1.9 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 1.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.6 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 1.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.6 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 4.2 GO:0021670 lateral ventricle development(GO:0021670)
0.2 0.8 GO:0009386 translational attenuation(GO:0009386)
0.2 1.2 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 1.6 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.2 2.0 GO:0060056 mammary gland involution(GO:0060056)
0.2 0.3 GO:0002572 pro-T cell differentiation(GO:0002572)
0.2 1.5 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 0.6 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.9 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 2.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 3.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 1.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.3 GO:0060166 olfactory pit development(GO:0060166)
0.1 1.3 GO:0006477 protein sulfation(GO:0006477)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.6 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 9.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.6 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 1.1 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.8 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 2.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.4 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 2.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 11.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.7 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.1 4.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 3.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.2 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.1 7.7 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.9 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.1 0.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.5 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 1.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.8 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.2 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 1.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 1.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 3.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 1.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 2.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0061734 negative regulation of receptor recycling(GO:0001920) parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 1.0 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 2.5 GO:0007004 telomere maintenance via telomerase(GO:0007004)
0.0 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.8 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.3 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:0048839 inner ear development(GO:0048839)
0.0 1.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.0 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 1.0 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 13.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.8 4.2 GO:0005879 axonemal microtubule(GO:0005879)
0.7 8.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.7 7.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.6 1.9 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.5 3.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.4 3.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 7.9 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.4 2.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 4.0 GO:0060091 kinocilium(GO:0060091)
0.3 2.3 GO:0043196 varicosity(GO:0043196)
0.3 2.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.3 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.0 GO:0031501 mannosyltransferase complex(GO:0031501)
0.2 0.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 2.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 10.6 GO:0016235 aggresome(GO:0016235)
0.1 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 2.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 4.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 5.4 GO:0097542 ciliary tip(GO:0097542)
0.1 1.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 3.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.0 3.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 6.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 10.8 GO:0005929 cilium(GO:0005929)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 2.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.3 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.7 13.6 GO:0042289 MHC class II protein binding(GO:0042289)
1.4 4.2 GO:0031862 prostanoid receptor binding(GO:0031862)
1.0 3.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.9 7.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.7 5.2 GO:0046979 TAP2 binding(GO:0046979)
0.6 1.9 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.6 7.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.5 10.1 GO:0070628 proteasome binding(GO:0070628)
0.4 7.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 2.6 GO:0043532 angiostatin binding(GO:0043532)
0.4 2.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.4 3.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.4 4.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 0.9 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 1.1 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.2 1.5 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 0.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 1.0 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.2 1.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 1.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 2.0 GO:0051525 NFAT protein binding(GO:0051525)
0.2 3.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 3.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 2.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 5.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 1.4 GO:0003682 chromatin binding(GO:0003682)
0.1 3.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 3.1 GO:0008527 taste receptor activity(GO:0008527)
0.1 4.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 6.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 3.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 3.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 4.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 2.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 3.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 17.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 5.2 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 6.2 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 1.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.7 PID CD40 PATHWAY CD40/CD40L signaling
0.2 1.9 PID IL27 PATHWAY IL27-mediated signaling events
0.1 5.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 8.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 5.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 8.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 3.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 7.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 2.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 3.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 8.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 3.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 5.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 12.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 4.5 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 2.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 2.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 5.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation