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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NFKB2

Z-value: 0.60

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Transcription factors associated with NFKB2

Gene Symbol Gene ID Gene Info
NFKB2
ENSG00000077150.13 nuclear factor kappa B subunit 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB2hg19_v2_chr10_+_104155450_104155479,
hg19_v2_chr10_+_104154229_104154354		0.451.2e-02Click!

Activity profile of NFKB2 motif

Sorted Z-values of NFKB2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74864386 1.58 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_-_186649543 1.29 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr5_+_7654057 1.19 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr22_-_37640456 1.10 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_37640277 1.06 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chrX_+_103173457 0.98 ENST00000419165.1
TMSB15B
thymosin beta 15B
chr8_+_86376081 0.90 ENST00000285379.5
CA2
carbonic anhydrase II
chr1_-_6545502 0.90 ENST00000535355.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_+_111718173 0.86 ENST00000494932.1
TAGLN3
transgelin 3
chr20_+_43803517 0.83 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr4_+_17812525 0.79 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr9_+_17579084 0.72 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr19_+_48824711 0.72 ENST00000599704.1
EMP3
epithelial membrane protein 3
chr8_+_54793454 0.70 ENST00000276500.4
RGS20
regulator of G-protein signaling 20
chr1_+_78354297 0.68 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr4_-_74904398 0.68 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr8_+_54793425 0.67 ENST00000522225.1
RGS20
regulator of G-protein signaling 20
chr18_+_21529811 0.67 ENST00000588004.1
LAMA3
laminin, alpha 3
chrX_+_64887512 0.66 ENST00000360270.5
MSN
moesin
chr1_-_38100539 0.66 ENST00000401069.1
RSPO1
R-spondin 1
chr19_-_19051927 0.63 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chr7_+_100547156 0.56 ENST00000379458.4
MUC3A
Protein LOC100131514
chr5_-_137667459 0.55 ENST00000415130.2
ENST00000356505.3
ENST00000357274.3
ENST00000348983.3
ENST00000323760.6
CDC25C
cell division cycle 25C
chr19_-_19049791 0.54 ENST00000594439.1
ENST00000221222.11
HOMER3
homer homolog 3 (Drosophila)
chr6_+_32605195 0.53 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr16_-_74734672 0.53 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr19_-_41859814 0.53 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr3_-_50340996 0.52 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr16_-_74734742 0.52 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr8_-_62559366 0.51 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr3_+_111717600 0.51 ENST00000273368.4
TAGLN3
transgelin 3
chr1_-_47655686 0.51 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr21_-_45079341 0.50 ENST00000443485.1
ENST00000291560.2
HSF2BP
heat shock transcription factor 2 binding protein
chr3_+_111718036 0.49 ENST00000455401.2
TAGLN3
transgelin 3
chr1_-_38100491 0.49 ENST00000356545.2
RSPO1
R-spondin 1
chr1_-_209824643 0.48 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr19_+_54371114 0.47 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM
myeloid-associated differentiation marker
chr10_+_104154229 0.46 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr9_+_75263565 0.44 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr10_+_112257596 0.42 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr1_+_111770278 0.42 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr2_-_89310012 0.42 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr19_-_52227221 0.42 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chrX_-_15872914 0.41 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_64681641 0.41 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr1_-_159915386 0.40 ENST00000361509.3
ENST00000368094.1
IGSF9
immunoglobulin superfamily, member 9
chr1_+_111770232 0.40 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr7_-_28220354 0.40 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr8_+_90770008 0.40 ENST00000540020.1
RIPK2
receptor-interacting serine-threonine kinase 2
chr7_+_120629653 0.39 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr4_-_74964904 0.39 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr15_-_89438742 0.39 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr8_-_145641864 0.38 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr11_-_18270182 0.38 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr5_+_60241020 0.37 ENST00000511107.1
ENST00000502658.1
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr16_+_88704978 0.37 ENST00000244241.4
IL17C
interleukin 17C
chr19_+_45147098 0.37 ENST00000425690.3
ENST00000344956.4
ENST00000403059.4
PVR
poliovirus receptor
chr5_+_60240943 0.37 ENST00000296597.5
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr22_+_44319648 0.36 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr17_+_4854375 0.36 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr2_-_241737128 0.36 ENST00000404283.3
KIF1A
kinesin family member 1A
chr22_+_35796108 0.36 ENST00000382011.5
ENST00000416905.1
MCM5
minichromosome maintenance complex component 5
chr19_-_50400212 0.36 ENST00000391826.2
IL4I1
interleukin 4 induced 1
chr3_-_108308241 0.36 ENST00000295746.8
KIAA1524
KIAA1524
chr20_+_60174827 0.35 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr1_+_150954493 0.35 ENST00000368947.4
ANXA9
annexin A9
chr10_+_124030819 0.35 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr1_-_231376836 0.34 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr19_-_4831701 0.34 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr22_+_35796056 0.34 ENST00000216122.4
MCM5
minichromosome maintenance complex component 5
chr2_-_89292422 0.34 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chrX_+_68048803 0.33 ENST00000204961.4
EFNB1
ephrin-B1
chr11_-_76381781 0.33 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chr19_+_45147313 0.33 ENST00000406449.4
PVR
poliovirus receptor
chr8_+_95565947 0.32 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr2_+_173940668 0.32 ENST00000375213.3
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr16_+_15737124 0.32 ENST00000396355.1
ENST00000396353.2
NDE1
nudE neurodevelopment protein 1
chr22_+_44319619 0.32 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr19_+_10216899 0.31 ENST00000428358.1
ENST00000393796.4
ENST00000253107.7
ENST00000556468.1
ENST00000393793.1
PPAN-P2RY11
PPAN
PPAN-P2RY11 readthrough
peter pan homolog (Drosophila)
chrX_+_150151824 0.31 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chr8_-_145582118 0.31 ENST00000455319.2
ENST00000331890.5
FBXL6
F-box and leucine-rich repeat protein 6
chr19_-_3786253 0.31 ENST00000585778.1
MATK
megakaryocyte-associated tyrosine kinase
chr6_-_32157947 0.31 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr12_+_110011571 0.30 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr12_-_127256772 0.30 ENST00000536517.1
LINC00944
long intergenic non-protein coding RNA 944
chr7_-_44229022 0.30 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr1_-_208417620 0.30 ENST00000367033.3
PLXNA2
plexin A2
chr2_-_89247338 0.30 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr15_-_75017711 0.30 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr17_-_39928106 0.30 ENST00000540235.1
JUP
junction plakoglobin
chr20_-_43753104 0.30 ENST00000372785.3
WFDC12
WAP four-disulfide core domain 12
chr6_+_32605134 0.30 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_+_30302805 0.29 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
CCNE1
cyclin E1
chr9_-_139965000 0.29 ENST00000409687.3
SAPCD2
suppressor APC domain containing 2
chr8_+_26371763 0.29 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chr14_+_97263641 0.29 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr19_-_3786354 0.29 ENST00000395040.2
ENST00000310132.6
MATK
megakaryocyte-associated tyrosine kinase
chr7_+_150811705 0.28 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr14_-_51297197 0.28 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr9_+_38392661 0.28 ENST00000377698.3
ALDH1B1
aldehyde dehydrogenase 1 family, member B1
chr18_+_268148 0.27 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chr17_-_34207295 0.27 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr12_+_57522258 0.27 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr1_-_154943212 0.27 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr11_+_35639735 0.26 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chr4_+_74702214 0.26 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr17_-_40333150 0.26 ENST00000264661.3
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_+_119056178 0.26 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr15_+_92937058 0.25 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr3_+_12329397 0.25 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr16_-_46864955 0.25 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr3_+_12329358 0.25 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr11_-_104840093 0.25 ENST00000417440.2
ENST00000444739.2
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr18_-_31802056 0.25 ENST00000538587.1
NOL4
nucleolar protein 4
chr12_-_77272765 0.25 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2
cysteine and glycine-rich protein 2
chr22_-_20255212 0.25 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr5_+_176730769 0.25 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr8_-_9008206 0.24 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr6_-_24646249 0.24 ENST00000430948.2
ENST00000537886.1
ENST00000535378.1
ENST00000378214.3
KIAA0319
KIAA0319
chr20_+_35090150 0.24 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr7_+_142031986 0.24 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chr5_+_176731572 0.24 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr1_-_28559502 0.24 ENST00000263697.4
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr9_-_123691047 0.24 ENST00000373887.3
TRAF1
TNF receptor-associated factor 1
chr16_-_68269971 0.23 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr6_-_43484621 0.23 ENST00000506469.1
ENST00000503972.1
YIPF3
Yip1 domain family, member 3
chr10_+_13141585 0.23 ENST00000378764.2
OPTN
optineurin
chr9_-_71155783 0.23 ENST00000377311.3
TMEM252
transmembrane protein 252
chr5_-_150466692 0.23 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr1_-_93426998 0.23 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr2_-_27718052 0.23 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr19_+_35485682 0.23 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr9_-_125667618 0.23 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr2_-_219157250 0.22 ENST00000434015.2
ENST00000444183.1
ENST00000420341.1
ENST00000453281.1
ENST00000258412.3
ENST00000440422.1
TMBIM1
transmembrane BAX inhibitor motif containing 1
chrX_-_15353629 0.22 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr2_+_173940163 0.22 ENST00000539448.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr20_-_48532019 0.22 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr6_-_43484718 0.22 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr1_-_154943002 0.22 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr10_-_86001210 0.22 ENST00000372105.3
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr12_+_8662057 0.22 ENST00000382064.2
CLEC4D
C-type lectin domain family 4, member D
chr20_-_42815733 0.21 ENST00000342272.3
JPH2
junctophilin 2
chr16_-_28223166 0.21 ENST00000304658.5
XPO6
exportin 6
chr19_-_50143452 0.21 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr1_-_183604794 0.21 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr19_+_19639670 0.21 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr17_+_38497640 0.21 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr16_+_31539197 0.21 ENST00000564707.1
AHSP
alpha hemoglobin stabilizing protein
chr8_+_32406179 0.21 ENST00000405005.3
NRG1
neuregulin 1
chr17_-_27045405 0.21 ENST00000430132.2
RAB34
RAB34, member RAS oncogene family
chr17_-_5487277 0.21 ENST00000572272.1
ENST00000354411.3
ENST00000577119.1
NLRP1
NLR family, pyrin domain containing 1
chr7_-_111202511 0.20 ENST00000452895.1
ENST00000452753.1
ENST00000331762.3
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr16_+_31539183 0.20 ENST00000302312.4
AHSP
alpha hemoglobin stabilizing protein
chr1_+_901847 0.20 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr10_-_133795416 0.20 ENST00000540159.1
ENST00000368636.4
BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
chr19_+_19639704 0.19 ENST00000514277.4
YJEFN3
YjeF N-terminal domain containing 3
chr17_+_4855053 0.19 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr11_-_64570706 0.19 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr1_-_205744574 0.19 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr2_+_173940442 0.19 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr8_+_22857048 0.19 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr22_+_38349670 0.19 ENST00000442738.2
ENST00000460648.1
ENST00000407936.1
ENST00000488684.1
ENST00000492213.1
ENST00000606538.1
ENST00000405557.1
POLR2F
polymerase (RNA) II (DNA directed) polypeptide F
chr7_-_129691201 0.19 ENST00000480193.1
ENST00000360708.5
ENST00000311873.5
ENST00000481503.1
ENST00000358303.4
ZC3HC1
zinc finger, C3HC-type containing 1
chr16_-_4465886 0.19 ENST00000539968.1
CORO7
coronin 7
chr22_-_25801333 0.19 ENST00000444995.3
LRP5L
low density lipoprotein receptor-related protein 5-like
chr8_-_37797621 0.18 ENST00000524298.1
ENST00000307599.4
GOT1L1
glutamic-oxaloacetic transaminase 1-like 1
chr1_-_6546001 0.18 ENST00000400913.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr7_-_44179972 0.18 ENST00000446581.1
MYL7
myosin, light chain 7, regulatory
chr2_-_70780770 0.18 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr21_+_17443521 0.18 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr16_+_31119615 0.18 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
BCKDK
branched chain ketoacid dehydrogenase kinase
chr17_-_27045427 0.18 ENST00000301043.6
ENST00000412625.1
RAB34
RAB34, member RAS oncogene family
chr1_-_205744205 0.18 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr8_+_128427857 0.18 ENST00000391675.1
POU5F1B
POU class 5 homeobox 1B
chr19_+_1450112 0.18 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr11_+_706113 0.18 ENST00000318562.8
ENST00000533256.1
ENST00000534755.1
EPS8L2
EPS8-like 2
chr17_-_42908155 0.18 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr12_-_49259643 0.18 ENST00000309739.5
RND1
Rho family GTPase 1
chr3_+_113775576 0.18 ENST00000485050.1
ENST00000281273.4
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr21_+_17442799 0.18 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr2_-_70781087 0.18 ENST00000394241.3
ENST00000295400.6
TGFA
transforming growth factor, alpha
chr10_+_13142075 0.17 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr21_+_17443434 0.17 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr1_-_41328018 0.17 ENST00000372638.2
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr17_-_27045165 0.17 ENST00000436730.3
ENST00000450529.1
ENST00000583538.1
ENST00000419712.3
ENST00000580843.2
ENST00000582934.1
ENST00000415040.2
ENST00000353676.5
ENST00000453384.3
ENST00000447716.1
RAB34
RAB34, member RAS oncogene family
chr11_+_60691924 0.17 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr1_-_71513471 0.17 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3
prostaglandin E receptor 3 (subtype EP3)
chrX_-_141293047 0.17 ENST00000247452.3
MAGEC2
melanoma antigen family C, 2
chr12_+_70760056 0.17 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr7_-_143059780 0.17 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr4_-_20985632 0.16 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr15_+_92397051 0.16 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr16_-_4466622 0.16 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
CORO7
coronin 7
chr8_-_144923112 0.16 ENST00000442628.2
NRBP2
nuclear receptor binding protein 2
chr15_+_92396920 0.16 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr9_+_115913222 0.16 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr14_+_21467414 0.16 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr7_-_151107767 0.16 ENST00000477459.1
WDR86
WD repeat domain 86
chr17_-_1389419 0.16 ENST00000575158.1
MYO1C
myosin IC
chr17_+_40172069 0.16 ENST00000393885.4
ENST00000393884.2
ENST00000587337.1
ENST00000479407.1
NKIRAS2
NFKB inhibitor interacting Ras-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 0.9 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.7 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 2.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.2 0.5 GO:1900126 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 0.5 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.6 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.4 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.5 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.7 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 0.5 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.1 3.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.1 GO:0045657 positive regulation of macrophage differentiation(GO:0045651) positive regulation of monocyte differentiation(GO:0045657)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.5 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 1.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:1905154 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417)
0.0 0.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.5 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.3 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.5 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.6 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.9 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.7 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:2000777 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 1.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 1.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.4 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.0 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.3 GO:0032288 myelin assembly(GO:0032288)
0.0 0.6 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.7 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0045202 synapse(GO:0045202)
0.0 1.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 2.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 1.2 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.2 GO:0005901 caveola(GO:0005901)
0.0 0.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 3.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.4 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.9 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 1.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.7 GO:0036042 lysophosphatidic acid binding(GO:0035727) long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.5 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.3 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.0 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.3 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 3.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis