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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NKX1-2_RAX

Z-value: 0.56

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Transcription factors associated with NKX1-2_RAX

Gene Symbol Gene ID Gene Info
NKX1-2
ENSG00000229544.6 NK1 homeobox 2
RAX
ENSG00000134438.9 retina and anterior neural fold homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RAXhg19_v2_chr18_-_56940611_56940660-0.135.0e-01Click!

Activity profile of NKX1-2_RAX motif

Sorted Z-values of NKX1-2_RAX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_35938674 7.77 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr12_+_7013897 4.90 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr12_+_7014064 4.88 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr12_+_7014126 3.95 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr12_-_25348007 3.03 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr13_+_36050881 2.79 ENST00000537702.1
NBEA
neurobeachin
chr11_+_71900703 1.60 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr11_+_71900572 1.56 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr4_+_77356248 1.53 ENST00000296043.6
SHROOM3
shroom family member 3
chr4_-_25865159 1.41 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr5_-_20575959 1.03 ENST00000507958.1
CDH18
cadherin 18, type 2
chr2_+_217524323 1.01 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr11_-_63376013 0.98 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr4_-_141348789 0.96 ENST00000414773.1
CLGN
calmegin
chr16_-_28608364 0.95 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_+_201979645 0.88 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr16_-_28608424 0.88 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr6_+_26402465 0.80 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr14_+_74034310 0.79 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr7_+_70597109 0.72 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr4_-_74486109 0.69 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_26440700 0.67 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chrX_+_77166172 0.65 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr13_+_78315295 0.61 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr4_-_74486347 0.57 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_+_160370344 0.50 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr3_+_186560462 0.50 ENST00000412955.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr3_+_186560476 0.50 ENST00000320741.2
ENST00000444204.2
ADIPOQ
adiponectin, C1Q and collagen domain containing
chr11_-_62521614 0.49 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr8_-_102803163 0.45 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr5_-_102898465 0.43 ENST00000507423.1
ENST00000230792.2
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr2_+_24714729 0.43 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr1_-_190446759 0.42 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr1_+_100818156 0.42 ENST00000336454.3
CDC14A
cell division cycle 14A
chr8_-_101571933 0.41 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr3_+_195447738 0.40 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr17_+_57232690 0.40 ENST00000262293.4
PRR11
proline rich 11
chr6_+_52442083 0.37 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr6_+_26402517 0.37 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr3_-_114790179 0.37 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_99717230 0.37 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr3_-_11685345 0.36 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr8_-_101571964 0.36 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46
ankyrin repeat domain 46
chr20_-_29978286 0.36 ENST00000376315.2
DEFB119
defensin, beta 119
chrX_+_77154935 0.36 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr3_+_140396881 0.36 ENST00000286349.3
TRIM42
tripartite motif containing 42
chr16_-_28937027 0.35 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr3_-_105587879 0.35 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr1_+_28261492 0.34 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr20_+_43990576 0.32 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr7_+_138145076 0.31 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr9_-_5339873 0.31 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr4_-_66536196 0.30 ENST00000511294.1
EPHA5
EPH receptor A5
chr6_-_167040731 0.30 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_-_13835147 0.29 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr6_+_26365443 0.29 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr7_-_87856280 0.24 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr12_-_23737534 0.24 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr4_-_74486217 0.24 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_-_87856303 0.24 ENST00000394641.3
SRI
sorcin
chr2_-_239197201 0.23 ENST00000254658.3
PER2
period circadian clock 2
chr1_+_100818009 0.22 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr11_-_59383617 0.22 ENST00000263847.1
OSBP
oxysterol binding protein
chr16_+_53133070 0.22 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr5_+_63802109 0.22 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr7_-_86849883 0.22 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr9_-_3469181 0.22 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr2_-_239197238 0.20 ENST00000254657.3
PER2
period circadian clock 2
chr8_+_105235572 0.20 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr11_-_124981475 0.19 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218
transmembrane protein 218
chr17_-_41466555 0.19 ENST00000586231.1
LINC00910
long intergenic non-protein coding RNA 910
chrX_-_8139308 0.19 ENST00000317103.4
VCX2
variable charge, X-linked 2
chr7_-_99717463 0.18 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr8_+_107738240 0.18 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chrX_-_6453159 0.18 ENST00000381089.3
ENST00000398729.1
VCX3A
variable charge, X-linked 3A
chr5_-_159546396 0.17 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr1_+_153747746 0.17 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr10_+_24755416 0.15 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr6_+_26501449 0.15 ENST00000244513.6
BTN1A1
butyrophilin, subfamily 1, member A1
chr3_+_23851928 0.14 ENST00000467766.1
ENST00000424381.1
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr8_-_135522425 0.14 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr4_-_66536057 0.14 ENST00000273854.3
EPHA5
EPH receptor A5
chrX_+_130192318 0.13 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr1_-_151804314 0.13 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr4_-_103748880 0.13 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr17_-_39341594 0.12 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr14_+_55493920 0.11 ENST00000395472.2
ENST00000555846.1
SOCS4
suppressor of cytokine signaling 4
chr14_+_55494323 0.11 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr8_+_107738343 0.10 ENST00000521592.1
OXR1
oxidation resistance 1
chrM_+_9207 0.10 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr1_+_153746683 0.10 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr11_+_112047087 0.10 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr14_+_22465771 0.10 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr11_+_22689648 0.09 ENST00000278187.3
GAS2
growth arrest-specific 2
chr3_-_191000172 0.09 ENST00000427544.2
UTS2B
urotensin 2B
chr1_-_92952433 0.08 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr11_-_13011081 0.08 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958
long intergenic non-protein coding RNA 958
chr2_-_198540719 0.08 ENST00000295049.4
RFTN2
raftlin family member 2
chr19_-_46285736 0.08 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr12_-_74686314 0.07 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr2_-_89597542 0.07 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr17_-_4938712 0.07 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr17_-_10372875 0.07 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr12_+_112279782 0.07 ENST00000550735.2
MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr2_-_220264703 0.07 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr7_-_99716952 0.06 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr11_+_5710919 0.06 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr9_+_34646651 0.06 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chrX_+_19362011 0.06 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr7_-_7575477 0.06 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr10_-_114206649 0.05 ENST00000369404.3
ENST00000369405.3
ZDHHC6
zinc finger, DHHC-type containing 6
chr14_+_22670455 0.05 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr6_+_154360357 0.05 ENST00000330432.7
ENST00000360422.4
OPRM1
opioid receptor, mu 1
chr11_+_73498898 0.04 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr3_+_158519654 0.04 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr5_+_66300446 0.04 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_+_54641444 0.04 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr9_+_34646624 0.04 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr1_+_43148059 0.04 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr4_+_110736659 0.04 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr12_-_12837423 0.04 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr3_+_186353756 0.03 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr1_-_17766198 0.03 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr5_-_82969405 0.02 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr20_-_29978383 0.02 ENST00000339144.3
ENST00000376321.3
DEFB119
defensin, beta 119
chr15_+_64680003 0.02 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr12_-_112279694 0.02 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1
MAPKAPK5 antisense RNA 1
chr8_+_9413410 0.02 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr12_+_16500571 0.02 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr11_-_102651343 0.01 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr22_-_32651326 0.01 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr7_+_21582638 0.01 ENST00000409508.3
ENST00000328843.6
DNAH11
dynein, axonemal, heavy chain 11
chr2_-_86422095 0.00 ENST00000254636.5
IMMT
inner membrane protein, mitochondrial
chr17_-_38821373 0.00 ENST00000394052.3
KRT222
keratin 222

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-2_RAX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.3 1.0 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.6 GO:0071284 cellular response to lead ion(GO:0071284)
0.2 0.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.4 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 1.5 GO:0045176 apical protein localization(GO:0045176)
0.1 1.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.9 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.5 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 1.0 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.3 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 0.5 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 1.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.2 0.6 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 1.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins