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Mucociliary differentiation, bronchial epithelial cells, human (Ross 2007)

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Results for NKX2-8

Z-value: 0.81

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
NKX2-8
ENSG00000136327.6 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg19_v2_chr14_-_37051798_370518310.532.5e-03Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_13349650 3.12 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr1_+_120839412 2.70 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr15_+_40453204 2.29 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chr17_+_76210367 2.15 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr1_+_152957707 2.01 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr14_-_24732403 1.87 ENST00000206765.6
TGM1
transglutaminase 1
chr19_-_51336443 1.65 ENST00000598673.1
KLK15
kallikrein-related peptidase 15
chr17_+_76210267 1.64 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr8_+_27182862 1.54 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr19_+_44037546 1.53 ENST00000601282.1
ZNF575
zinc finger protein 575
chr14_-_24732368 1.49 ENST00000544573.1
TGM1
transglutaminase 1
chr1_+_154401791 1.44 ENST00000476006.1
IL6R
interleukin 6 receptor
chr20_+_58296265 1.44 ENST00000395636.2
ENST00000361300.4
PHACTR3
phosphatase and actin regulator 3
chr20_+_31619454 1.28 ENST00000349552.1
BPIFB6
BPI fold containing family B, member 6
chr2_+_136289030 0.99 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1
R3H domain containing 1
chr11_-_128457446 0.97 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr11_-_107590383 0.93 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr15_-_70387120 0.87 ENST00000539550.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr2_+_101591314 0.87 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr3_-_53290016 0.85 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
TKT
transketolase
chr3_-_47950745 0.83 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr14_-_106573756 0.81 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr1_+_10057274 0.79 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr5_-_78808617 0.78 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr13_-_23949671 0.77 ENST00000402364.1
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_-_94147385 0.77 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr16_+_8807419 0.76 ENST00000565016.1
ENST00000567812.1
ABAT
4-aminobutyrate aminotransferase
chr16_+_88872176 0.76 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr8_-_62559366 0.69 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr17_-_8055747 0.69 ENST00000317276.4
ENST00000581703.1
PER1
period circadian clock 1
chr6_+_69942298 0.69 ENST00000238918.8
BAI3
brain-specific angiogenesis inhibitor 3
chr2_-_36779411 0.67 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr11_+_35211429 0.66 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr14_-_106791536 0.66 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr12_-_118406777 0.65 ENST00000339824.5
KSR2
kinase suppressor of ras 2
chr7_+_135242652 0.64 ENST00000285968.6
ENST00000440390.2
NUP205
nucleoporin 205kDa
chr22_-_50523760 0.63 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_-_39290744 0.63 ENST00000507712.1
KCNK16
potassium channel, subfamily K, member 16
chrX_-_64196376 0.62 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chrX_-_64196307 0.58 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr11_+_5410607 0.58 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr3_+_111717600 0.58 ENST00000273368.4
TAGLN3
transgelin 3
chr7_+_73507409 0.58 ENST00000538333.3
LIMK1
LIM domain kinase 1
chr3_+_111717511 0.57 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chrX_-_64196351 0.56 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr8_-_145018905 0.55 ENST00000398774.2
PLEC
plectin
chr3_+_47021168 0.55 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
NBEAL2
neurobeachin-like 2
chr20_-_48747662 0.53 ENST00000371656.2
TMEM189
transmembrane protein 189
chr14_-_106586656 0.53 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr16_+_23194033 0.52 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chr17_+_61086917 0.52 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr7_+_129847688 0.51 ENST00000297819.3
SSMEM1
serine-rich single-pass membrane protein 1
chr15_-_20170354 0.51 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr7_+_30634297 0.50 ENST00000389266.3
GARS
glycyl-tRNA synthetase
chr19_+_34856141 0.50 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr2_-_136288740 0.50 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr4_+_71200681 0.50 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chr4_+_37245799 0.50 ENST00000309447.5
KIAA1239
KIAA1239
chr6_+_41010293 0.49 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2
translocator protein 2
chr13_-_46756351 0.49 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_116782527 0.49 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr16_-_20681177 0.49 ENST00000524149.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr10_+_74653330 0.48 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr4_-_123377880 0.47 ENST00000226730.4
IL2
interleukin 2
chrX_+_41548220 0.47 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr14_-_107049312 0.47 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr3_-_58613323 0.47 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr1_+_228337553 0.47 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr4_-_69111401 0.46 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chrX_+_41548259 0.46 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr1_+_16348525 0.45 ENST00000331433.4
CLCNKA
chloride channel, voltage-sensitive Ka
chr12_+_66218903 0.44 ENST00000393577.3
HMGA2
high mobility group AT-hook 2
chr16_+_58426296 0.44 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS3
GINS complex subunit 3 (Psf3 homolog)
chr7_-_766879 0.44 ENST00000537384.1
ENST00000417852.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr15_-_99057551 0.43 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr2_-_46385 0.43 ENST00000327669.4
FAM110C
family with sequence similarity 110, member C
chr2_-_110371720 0.43 ENST00000356688.4
SEPT10
septin 10
chr6_-_32145861 0.42 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr11_+_64808675 0.42 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr12_+_9144626 0.41 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr1_+_158223923 0.41 ENST00000289429.5
CD1A
CD1a molecule
chr5_+_14664762 0.39 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr16_+_32063311 0.39 ENST00000426099.1
AC142381.1
AC142381.1
chr16_+_32077386 0.39 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr3_-_116163830 0.38 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr14_+_24540046 0.38 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr14_+_22356029 0.38 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr9_-_21166659 0.37 ENST00000380225.1
IFNA21
interferon, alpha 21
chr14_-_106068065 0.37 ENST00000390541.2
IGHE
immunoglobulin heavy constant epsilon
chr17_-_33390667 0.37 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr4_-_153601136 0.36 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr12_+_121416489 0.35 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr7_+_112063192 0.35 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr14_-_106552755 0.35 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr3_-_178984759 0.35 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr2_-_106054952 0.33 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr8_+_67405755 0.33 ENST00000521495.1
C8orf46
chromosome 8 open reading frame 46
chr1_-_155006224 0.33 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr19_-_18391708 0.32 ENST00000600972.1
JUND
jun D proto-oncogene
chr12_-_102591604 0.32 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr22_-_32341336 0.32 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr7_-_99277610 0.32 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr2_-_68547061 0.32 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr19_+_2249308 0.31 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr1_-_95007193 0.31 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr14_-_106692191 0.30 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr1_+_12040238 0.30 ENST00000444836.1
ENST00000235329.5
MFN2
mitofusin 2
chr9_-_22009297 0.30 ENST00000276925.6
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_+_173793777 0.30 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr4_-_170947565 0.30 ENST00000506764.1
MFAP3L
microfibrillar-associated protein 3-like
chr11_-_72353451 0.30 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr5_-_101834617 0.30 ENST00000513675.1
ENST00000379807.3
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr10_+_71078595 0.29 ENST00000359426.6
HK1
hexokinase 1
chr6_+_34433844 0.29 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr4_+_144303093 0.29 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr5_-_101834712 0.28 ENST00000506729.1
ENST00000389019.3
ENST00000379810.1
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr12_-_11548496 0.28 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr14_-_58894332 0.28 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr16_+_33006369 0.27 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr16_+_33629600 0.27 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr14_-_107131560 0.27 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr4_-_819901 0.27 ENST00000304062.6
CPLX1
complexin 1
chr12_-_75603643 0.26 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_+_66218598 0.26 ENST00000541363.1
HMGA2
high mobility group AT-hook 2
chr17_+_71228793 0.25 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr5_-_176056974 0.25 ENST00000510387.1
ENST00000506696.1
SNCB
synuclein, beta
chr12_-_75603482 0.25 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_-_75603202 0.25 ENST00000393288.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr9_-_21202204 0.25 ENST00000239347.3
IFNA7
interferon, alpha 7
chr3_-_53164423 0.25 ENST00000467048.1
ENST00000394738.3
ENST00000296292.3
RFT1
RFT1 homolog (S. cerevisiae)
chr2_-_29297127 0.25 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr1_-_67266939 0.24 ENST00000304526.2
INSL5
insulin-like 5
chr22_+_38609538 0.24 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chrX_-_53461288 0.24 ENST00000375298.4
ENST00000375304.5
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr5_+_74011328 0.23 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr6_-_32806506 0.23 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr14_-_58894223 0.23 ENST00000555593.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr5_+_149737202 0.23 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr2_-_132249955 0.23 ENST00000309451.6
MZT2A
mitotic spindle organizing protein 2A
chr13_-_103346854 0.22 ENST00000267273.6
METTL21C
methyltransferase like 21C
chr16_+_89696692 0.22 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr12_+_7941989 0.22 ENST00000229307.4
NANOG
Nanog homeobox
chr7_-_36764142 0.22 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr9_-_128412696 0.22 ENST00000420643.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr14_+_22670455 0.22 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr14_+_92980111 0.21 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr1_+_151512775 0.21 ENST00000368849.3
ENST00000392712.3
ENST00000353024.3
ENST00000368848.2
ENST00000538902.1
TUFT1
tuftelin 1
chr3_-_16524357 0.20 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr12_-_75603236 0.20 ENST00000540018.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr2_+_207024306 0.20 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chrX_+_72064690 0.19 ENST00000438696.1
DMRTC1B
DMRT-like family C1B
chr19_-_11347173 0.19 ENST00000587656.1
DOCK6
dedicator of cytokinesis 6
chr3_-_73673991 0.19 ENST00000308537.4
ENST00000263666.4
PDZRN3
PDZ domain containing ring finger 3
chr14_-_107199464 0.19 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr2_-_55277692 0.18 ENST00000394611.2
RTN4
reticulon 4
chr12_+_66218212 0.18 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr2_-_55277654 0.18 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4
reticulon 4
chr3_+_52812523 0.18 ENST00000540715.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr2_-_207024134 0.18 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr3_+_52813932 0.17 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr14_-_106963409 0.17 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr1_+_224301787 0.17 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr22_-_37213554 0.17 ENST00000443735.1
PVALB
parvalbumin
chr3_-_196242233 0.17 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr22_+_38453207 0.17 ENST00000404072.3
ENST00000424694.1
PICK1
protein interacting with PRKCA 1
chr18_-_73139589 0.16 ENST00000382638.3
ENST00000584508.1
ENST00000579022.1
SMIM21
small integral membrane protein 21
chr12_+_60058458 0.15 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr6_+_125524785 0.15 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr10_-_15762124 0.15 ENST00000378076.3
ITGA8
integrin, alpha 8
chr20_+_42143136 0.15 ENST00000373134.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr6_+_111408698 0.15 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr8_+_128426535 0.15 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr13_+_46039037 0.14 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr16_+_29674540 0.14 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr14_-_107219365 0.14 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr4_+_141264597 0.13 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr17_+_39994032 0.13 ENST00000293303.4
ENST00000438813.1
KLHL10
kelch-like family member 10
chr1_+_74701062 0.13 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr12_-_5352315 0.13 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr2_-_207023918 0.13 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr8_+_24241789 0.13 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr5_+_3596168 0.12 ENST00000302006.3
IRX1
iroquois homeobox 1
chr12_-_21810765 0.12 ENST00000450584.1
ENST00000350669.1
LDHB
lactate dehydrogenase B
chr3_+_63953415 0.12 ENST00000484332.1
ATXN7
ataxin 7
chr9_-_21239978 0.12 ENST00000380222.2
IFNA14
interferon, alpha 14
chr16_-_33647696 0.11 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9
Uncharacterized protein
chr12_-_95397442 0.11 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr11_-_19223523 0.11 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr18_-_13915530 0.11 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr21_-_35899113 0.11 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr12_-_21810726 0.11 ENST00000396076.1
LDHB
lactate dehydrogenase B
chr16_-_75301886 0.11 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr3_-_139195350 0.11 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr2_-_55277436 0.10 ENST00000354474.6
RTN4
reticulon 4
chr6_-_133084580 0.10 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2
vanin 2
chr4_+_15341442 0.10 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr5_-_78281775 0.10 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr5_+_80529104 0.10 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
CKMT2
creatine kinase, mitochondrial 2 (sarcomeric)
chr3_+_67048721 0.09 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr10_-_118032697 0.09 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.6 2.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.5 1.4 GO:0002384 hepatic immune response(GO:0002384)
0.4 1.5 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.3 0.9 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.3 0.3 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543)
0.3 0.9 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 0.8 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 0.8 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.9 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.2 0.8 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.2 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.2 3.8 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2 0.5 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.8 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 0.5 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.0 GO:0030578 PML body organization(GO:0030578)
0.1 3.1 GO:0032060 bleb assembly(GO:0032060)
0.1 1.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.7 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.2 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.3 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0007619 courtship behavior(GO:0007619)
0.0 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.9 GO:0051775 response to redox state(GO:0051775)
0.0 3.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.1 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 2.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 3.3 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.4 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 1.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.8 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 2.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 5.4 GO:0001533 cornified envelope(GO:0001533)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 3.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 3.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.5 1.4 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.3 3.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.9 GO:0035501 MH1 domain binding(GO:0035501)
0.2 0.9 GO:0004802 transketolase activity(GO:0004802)
0.2 0.8 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 0.5 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 3.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.1 0.5 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.5 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.9 GO:0019841 retinol binding(GO:0019841)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.8 PID AURORA A PATHWAY Aurora A signaling
0.1 1.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 3.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling